Research Topics
| Lynn D CornellSummaryAffiliation: Massachusetts Institute of Technology Country: USA Publications
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Detail Information
Publications
Pseudotumors due to IgG4 immune-complex tubulointerstitial nephritis associated with autoimmune pancreatocentric diseaseLynn D Cornell
Departments of Pathology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
Am J Surg Pathol 31:1586-97. 2007....
IgG4-related tubulointerstitial nephritisLynn D Cornell
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA
Kidney Int 78:951-3. 2010..Notably, some cases may be mass-forming. Recognition of this specific type of TIN can guide appropriate patient therapy...
Proliferative glomerulonephritis with monoclonal IgG deposits recurs in the allograftSamih H Nasr
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
Clin J Am Soc Nephrol 6:122-32. 2011..Proliferative GN with monoclonal IgG deposits (PGNMID) is a newly described entity resembling immune complex GN. Its potential to recur in the allograft is undefined...
Association of kidney function and metabolic risk factors with density of glomeruli on renal biopsy samples from living donorsAndrew D Rule
Division of Nephrology and Hypertension, Mayo Clinic, 200 First St SW, Rochester, MN 55905
Mayo Clin Proc 86:282-90. 2011..To test the hypothesis that kidney function and metabolic risk factors are associated with glomerular density on renal biopsy samples from healthy adults...
C1q deposition in the renal allograft: a report of 24 casesSamar M Said
Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Mod Pathol 23:1080-8. 2010..The rate of preceding infection and the prevalence of proteinuria seem to be similar to the renal transplant recipients in general. Most cases show mesangial hypercellularity or no glomerular changes on light microscopy...
Fibrillary glomerulonephritis: a report of 66 cases from a single institutionSamih H Nasr
Mayo Clinic, Division of Anatomic Pathology, Hilton 10 20, 200 First Street SW, Rochester, MN 55905, USA
Clin J Am Soc Nephrol 6:775-84. 2011..Most previously reported cases were idiopathic. To better define the clinical-pathologic spectrum and prognosis, we report the largest single-center series with the longest follow-up...
Renal monoclonal immunoglobulin deposition disease: a report of 64 patients from a single institutionSamih H Nasr
Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First Street SW, Hilton 10 20, Rochester, MN 55905, USA
Clin J Am Soc Nephrol 7:231-9. 2012..To better define the clinical-pathologic spectrum and prognosis of monoclonal immunoglobulin deposition disease (MIDD), this study reports the largest series...
Acquired glomerular lesions in patients with Down syndromeSamar M Said
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Hum Pathol 43:81-8. 2012..Renal biopsy is necessary to determine the type of glomerular lesion and appropriate treatment...
Myeloproliferative neoplasms cause glomerulopathySamar M Said
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA
Kidney Int 80:753-9. 2011..Greater awareness of this entity and larger studies are needed to define possible therapies...
Postinfectious glomerulonephritis in the elderlySamih H Nasr
Mayo Clinic, Division of Anatomic Pathology, Hilton 10 20, 200 First Street, SW, Rochester, MN 55905, USA
J Am Soc Nephrol 22:187-95. 2011..Prognosis for these older patients is poor, with fewer than 25% recovering full renal function...
Mass spectrometry-based proteomic diagnosis of renal immunoglobulin heavy chain amyloidosisSanjeev Sethi
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Clin J Am Soc Nephrol 5:2180-7. 2010..We also describe the clinicopathologic findings of four problematic cases of renal Ig heavy chain amyloidosis that required LMD/MS proteomic analysis for accurate typing of the amyloid...
Fibrosis with inflammation at one year predicts transplant functional declineWalter D Park
Department of Surgery, Division of Transplantation Surgery, Mayo Clinic, Rochester, Minnesota, USA
J Am Soc Nephrol 21:1987-97. 2010..Early interventions aimed at altering rejection-like inflammation may improve long-term survival of kidney allografts...
Diagnosis of IgG4-related tubulointerstitial nephritisYassaman Raissian
Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 1 Street SW, Rochester, MN 55905, USA
J Am Soc Nephrol 22:1343-52. 2011..When the disease manifests in the kidney, our data support diagnostic criteria that can distinguish IgG4-TIN from other types of TIN...
Distinctive pulmonary histopathology with increased IgG4-positive plasma cells in patients with autoimmune pancreatitis: report of 6 and 12 cases with similar histopathologyBijayee Shrestha
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Am J Surg Pathol 33:1450-62. 2009..The significance of increased IgG4+ cells in high proportion of RD cases merits further study as does overlap of RD and IgG4 disease...
The association between age and nephrosclerosis on renal biopsy among healthy adultsAndrew D Rule
Mayo Clinic, Rochester, Minnesota, USA
Ann Intern Med 152:561-7. 2010..Chronic kidney disease is common with older age and is characterized on renal biopsy by global glomerulosclerosis, tubular atrophy, interstitial fibrosis, and arteriosclerosis...
Dense deposit disease associated with monoclonal gammopathy of undetermined significanceSanjeev Sethi
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Am J Kidney Dis 56:977-82. 2010..Thus, DDD in some older patients may be a distinct clinicopathologic entity that represents an uncommon complication of MGUS...
Coronary artery disease from isolated non-H2-determined incompatibilities in transplanted mouse heartsPaul S Russell
Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
Transplantation 91:847-52. 2011..This report describes examples of coronary vascular disease occurring in transplanted mouse hearts involving isolated, non-H2-determined incompatibilities...
Crystalline nephropathy due to 2,8-dihydroxyadeninuria: an under-recognized cause of irreversible renal failureSamih H Nasr
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
Nephrol Dial Transplant 25:1909-15. 2010..Only rare cases of DHA nephrolithiasis have been reported from the USA. Herein, we report three American patients who developed DHA crystalline nephropathy leading to end-stage renal disease (ESRD) with recurrence in the allograft...
Antibody-mediated rejection following transplantation from an HLA-identical siblingCarrie A Grafft
Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
Nephrol Dial Transplant 25:307-10. 2010..A biopsy for allograft dysfunction suggested AMR, but DSA could not be detected. Treatment for rejection was transiently successful. Undetectable minor histocompatibility antibodies may have contributed...
