Research Topics
Species | Amy S ColwellSummaryAffiliation: Massachusetts General Hospital Country: USA Publications
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Publications
An inferolateral approach to nipple-sparing mastectomy: optimizing mastectomy and reconstructionAmy S Colwell
Mass General Hospital, Boston, MA 02114, USA
Ann Plast Surg 65:140-3. 2010..The incision allows adequate access and hides the scar on anterior view, thus optimizing both the mastectomy and reconstruction. In patients with a preexisting lateral scar, this may be the incision of choice...- Fetal wound healingAmy S Colwell
Department of Surgery, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Front Biosci 8:s1240-8. 2003..Further research may reveal novel genes essential to scarless repair that can be manipulated in the adult wound and thus ameliorate scar... - Near-infrared spectroscopy in autologous breast reconstructionAmy S Colwell
Division of Plastic Surgery, Massachusetts General Hospital, 15 Parkman Street, Boston, MA 02114, USA
Clin Plast Surg 38:301-7. 2011..This article focuses on the available data for one new technology, near-infrared spectroscopy, and its current use in clinical practice... - Near-infrared spectroscopy measures tissue oxygenation in free flaps for breast reconstructionAmy S Colwell
Department of Surgery, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
Plast Reconstr Surg 121:344e-345e. 2008 - Mastopexy techniques after massive weight loss: an algorithmic approach and review of the literatureAmy S Colwell
Division of Plastic Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Ann Plast Surg 63:28-33. 2009..This article offers an algorithmic approach to treat breast ptosis in the MWL patient based on breast volume, axillary tissue, desired scar location, and preferred surgical technique... - Low scar abdominoplasty with inferior positioning of the umbilicusAmy S Colwell
Division of Plastic Surgery, Mass General Hospital, Boston, MA 02114, USA
Ann Plast Surg 64:639-44. 2010..In conclusion, lower abdominoplasty with inferior umbilical positioning is an excellent choice for the middle age, postpartum woman with excess abdominal skin and full length diastasis recti but a normal body mass index... - Current concepts in post-bariatric body contouringAmy S Colwell
Division of Plastic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Obes Surg 20:1178-82. 2010..The author sought to review key concepts in patient selection, technical advancements, and post-operative care in body contouring following weight loss surgery... - Fetal and adult fibroblasts have similar TGF-beta-mediated, Smad-dependent signaling pathwaysAmy S Colwell
Department of Surgery, Division of Plastic Surgery, Children's Surgical Research Program, Tissue Regeneration Laboratory, Stanford, Calif. 94305-5148, USA
Plast Reconstr Surg 117:2277-83. 2006..This suggests that scarless healing is likely not mediated by different Smad-dependent transcriptional responses to TGF-beta isoforms in the fetal E17 fibroblast... - Wnt-4 expression is increased in fibroblasts after TGF-beta1 stimulation and during fetal and postnatal wound repairAmy S Colwell
Department of Surgery, Division of Plastic Surgery, Children's Surgical Research Program, Stanford, Calif. 94305-5148, USA
Plast Reconstr Surg 117:2297-301. 2006..CONCLUSION: The authors' data suggest that TGF-beta directly increases Wnt-4 expression in fetal and postnatal fibroblasts and that Wnt-4 is increased in both fetal and postnatal repair... - Early-gestation fetal scarless wounds have less lysyl oxidase expressionAmy S Colwell
Department of Surgery, Division of Plastic Surgery, Children s Surgical Research Program, Tissue Regeneration Laboratory, Stanford, Calif 94305 5148, USA
Plast Reconstr Surg 118:1125-9; discussion 1130-1. 2006..Lysyl oxidase cross-links collagen and elastin. Because cross-linking likely influences collagen architecture, the authors compared lysyl oxidase expression during scarless and scarring fetal dermal wound repair... - Keratinocytes modulate fetal and postnatal fibroblast transforming growth factor-beta and Smad expression in co-cultureAmy S Colwell
Department of Surgery, Division of Plastic Surgery, Children s Surgical Research Program, Tissue Regeneration Laboratory, Stanford, CA 94305 5148, USA
Plast Reconstr Surg 119:1440-5. 2007..The authors hypothesized that keratinocytes may differentially modulate expression of key growth factors expressed during wound healing in fetal and postnatal fibroblasts... - An in vivo mouse excisional wound model of scarless healingAmy S Colwell
Department of Surgery, Division of Plastic Surgery, Children's Surgical Research Program, Stanford, Calif. 94305-5148, USA
Plast Reconstr Surg 117:2292-6. 2006..The knowledge gained may be used to manipulate scarring in the adult to produce a more fetal-like wound... - Retrospective review of 331 consecutive immediate single-stage implant reconstructions with acellular dermal matrix: indications, complications, trends, and costsAmy S Colwell
Boston, Mass From the Division of Plastic Surgery, Massachusetts General Hospital, Harvard Medical School
Plast Reconstr Surg 128:1170-8. 2011..Immediate single-stage direct-to-implant breast reconstruction with acellular dermal matrix optimizes aesthetics by preserving the mastectomy skin envelope. The authors report trends, early complications, and costs... - Identification of differentially regulated genes in fetal wounds during regenerative repairAmy S Colwell
Division of Plastic Surgery, Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA
Wound Repair Regen 16:450-9. 2008..Our data suggest that multiple gene products may be necessary for the coordination of skin regeneration during wound repair in the fetus... - Transforming growth factor-beta, Smad, and collagen expression patterns in fetal and adult keratinocytesAmy S Colwell
Department of Surgery, Division of Plastic Surgery, Children s Surgical Research Program, Tissue Regeneration Laboratory, Stanford University, Stanford, CA 94305 5148, USA
Plast Reconstr Surg 119:852-7. 2007.... - Mammalian fetal organ regenerationAmy S Colwell
Department of Surgery, Pediatric Surgical Research Laboratory, Stanford University School of Medicine, 257 Campus Drive, Stanford, CA 94305-5148, USA
Adv Biochem Eng Biotechnol 93:83-100. 2005..Identification of more key genes involved in skin regeneration may have implications in adult skin wounds and repair in other organ systems... - Increased angiogenesis and expression of vascular endothelial growth factor during scarless repairAmy S Colwell
Department of Surgery, Division of Plastic Surgery, Stanford University School of Medicine, Stanford, Calif 94305-5148, USA
Plast Reconstr Surg 115:204-12. 2005..VEGF expression quickly elevates during scarless compared with scarring repair, which likely contributes to the more rapid scarless fetal repair rate. Similar numbers of new ves-sels are formed during scarless and scarring fetal repair... - Skin wounds in the MRL/MPJ mouse heal with scarAmy S Colwell
Department of Surgery, Division of Plastic Surgery, Pediatric Surgery Research Laboratory, Stanford University Medical School, Stanford, California 94305-5148, USA
Wound Repair Regen 14:81-90. 2006..In conclusion, in contrast to wound healing in the ear, MRL/MpJ mouse dorsal cutaneous wounds heal similarly to C57bl/6 and Balb/c mice with dermal collagen deposition and scar formation... - Improving shape and symmetry in mastopexy with autologous or cadaveric dermal slingsAmy S Colwell
Division of Plastic Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA, USA
Ann Plast Surg 61:138-42. 2008..In conclusion, internal dermal slings improve shape, breast projection, and base width in select patients undergoing mastopexy. An algorithm based on quantity and quality of native skin is provided... - Optimization of patient safety in postbariatric body contouring: a current reviewAmy S Colwell
Division of Plastic Surgery, Massachusetts General Hospital, Boston, MA, USA
Aesthet Surg J 28:437-42. 2008..Postoperative management is optimized by the development of clinical pathways involving the surgeon, patient, and support staff... - Breast augmentation after reduction mammaplasty: getting the size rightAmy S Colwell
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Ann Plast Surg 60:372-4. 2008..Breast augmentation may improve body image in patients with small breasts after reduction... - Occult breast carcinoma in reduction mammaplasty specimens: 14-year experienceAmy S Colwell
Department of Surgery, Brigham and Women's Hospital, Boston, Mass 02115, USA
Plast Reconstr Surg 113:1984-8. 2004..Pathological diagnosis was guided by gross specimen evaluation in two patients and specimen radiography in one patient. Reduction mammaplasty has a small but definite risk of finding cancer in the resection specimen... - Inferolateral AlloDerm hammock for implant coverage in breast reconstructionKarl H Breuing
Department of Surgery, Division of Plastic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Ann Plast Surg 59:250-5. 2007..We have been using an inferolateral AlloDerm hammock as an inferior extension of the pectoralis major muscle to provide a mechanical barrier between the implant and skin and to control implant position... - Lowering the postoperative high-riding nippleAmy S Colwell
Department of Surgery, Division of Plastic Surgery, Massachusetts General Hospital, and Beth Israel Deaconess Hospital, Harvard Medical School, Boston, MA, USA
Plast Reconstr Surg 120:596-9. 2007 - Autologous gluteal augmentation after massive weight loss: aesthetic analysis and role of the superior gluteal artery perforator flapAmy S Colwell
Division of Plastic Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Plast Reconstr Surg 119:345-56. 2007..The authors describe their technique of lower body lift with gluteal autologous augmentation using the superior gluteal artery perforator flap... - Immediate breast tissue expander-implant reconstruction with inferolateral AlloDerm hammock and postoperative radiation: a preliminary reportKarl H Breuing
Department of Surgery, Division of Plastic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Eplasty 9:e16. 2009..We hypothesized that the AlloDerm hammock may allow greater intraoperative volume expansion and potentially avoid the need for an autologous construct... - Hypertrophic scar fibroblasts have increased connective tissue growth factor expression after transforming growth factor-beta stimulationAmy S Colwell
Division of Plastic Surgery, Department of Surgery, Children's Surgical Research Program, Stanford University School of Medicine, Stanford, California, USA
Plast Reconstr Surg 116:1387-90; discussion 1391-2. 2005..These data suggest that blockage of CTGF activity may reduce pathologic scar formation... - Management of early groin vascular bypass graft infections with sartorius and rectus femoris flapsAmy S Colwell
Department of Surgery, Brigham and Women's Hospital, Boston, MA 02115, USA
Ann Plast Surg 52:49-53. 2004..Groin wounds healed in all patients without subsequent graft exposure, rupture, or pseudoaneurysm. Local wound therapy with staged debridement and muscle flaps is effective for most early localized graft infections... - The role of muscle flaps in pulmonary aspergillosisAmy S Colwell
Department of Surgery, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA
Plast Reconstr Surg 111:1147-50. 2003..Despite aggressive medical and surgical therapy, pulmonary aspergillosis has a poor prognosis... - Fat grafting to the breast revisited: safety and efficacyAmy S Colwell
Plast Reconstr Surg 121:701-2. 2008 - Fat grafting to the breast revisited: safety and efficacyAmy S Colwell
Plast Reconstr Surg 121:340-1. 2008 - Detection of perfusion disturbances in digit replantation using near-infrared spectroscopy and serial quantitative fluoroscopyAmy S Colwell
California Pacific Medical Center, San Francisco, CA 94114, USA
J Hand Surg [Am] 31:456-62. 2006..This noninvasive monitoring is easy, reliable, safe, and useful in postoperative monitoring of digit replantation. TYPE OF STUDY/LEVEL OF EVIDENCE: Diagnostic, Level I...
Research Grants
- Microarray Analysis of WoundsAMY COLWELL; Fiscal Year: 2004..We hypothesize these genes can be used to modulate the biology of adult wound healing. This first step will form our basis for developing treatment to induce scarless healing. ..