Research Topics
| Li-Ru ZhaoSummaryAffiliation: Louisiana State University Health Sciences Center Country: USA Publications
| Collaborators
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Detail Information
Publications
Stem cell factor and granulocyte colony-stimulating factor reduce ?-amyloid deposits in the brains of APP/PS1 transgenic miceBin Li
Department of Neurology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA
Alzheimers Res Ther 3:8. 2011..The purpose of the present study is to determine whether SCF+G-CSF can reduce the burden of ?-amyloid deposits in a mouse model of AD...- Beneficial effects of hematopoietic growth factor therapy in chronic ischemic stroke in ratsLi Ru Zhao
Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, Ill, USA
Stroke 38:2804-11. 2007..We have previously observed that SCF and G-CSF have neuroprotective and functional effects on acute brain ischemia. In the present study, the beneficial effects of SCF and G-CSF on chronic brain ischemia were determined... - Multiphoton microscope imaging: the behavior of neural progenitor cells in the rostral migratory streamLi Ru Zhao
Department of Neurology, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Chicago, IL 60611, USA
Neurosci Lett 425:83-8. 2007..Cell-cell contacts and microenvironmental changes influence NPC behavior in the RMS. This study may provide insights to help in understanding NPC biology... - Brain repair by hematopoietic growth factors in a rat model of strokeLi Ru Zhao
Department of Neurology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
Stroke 38:2584-91. 2007..We determined whether receptors for SCF and G-CSF exist in the brain and whether exogenous SCF and G-CSF are beneficial to brain repair after brain ischemia... - Hematopoietic growth factors pass through the blood-brain barrier in intact ratsLi Ru Zhao
Department of Neurology, Northwestern University, Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60611, USA
Exp Neurol 204:569-73. 2007..This observation will help in further exploring the physiological role of peripheral SCF and G-CSF in the brain and therapeutic possibility to chronic stroke... - Synthetic fibronectin peptide exerts neuroprotective effects on transient focal brain ischemia in ratsLi Ru Zhao
Department of Neurosurgery, University of Minnesota Medical School, Minneapolis, MN 55455, USA
Brain Res 1054:1-8. 2005..These data indicate that the peptide PRARIY exerts its neuroprotective effects via supporting neural cell survival rather than anti-leukocyte recruitment following brain ischemia/reperfusion injury... - Dual function of Sox1 in telencephalic progenitor cellsLixin Kan
Department of Neurology, Northwestern University Feinberg School of Medicine, 303 E Chicago Ave, Ward 10 233, Chicago, IL 60611 3008, USA
Dev Biol 310:85-98. 2007.... - Brain self-protection: the role of endogenous neural progenitor cells in adult brain after cerebral cortical ischemiaBin Li
Department of Neurology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA
Brain Res 1327:91-102. 2010..This study provides insights into the contribution of endogenous NSCs/NPCs to brain self-protection in adult brain after ischemia injury... - Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of ratsLi-Ru Zhao
Department of Neurosurgery, University of Minnesota, 55455, USA
Exp Neurol 174:11-20. 2002..The observed functional improvement might have been mediated by proteins secreted by transplanted hMSCs, which could have upregulated host brain plasticity in response to experimental stroke... - Immunohistochemical identification of multipotent adult progenitor cells from human bone marrow after transplantation into the rat brainLi-Ru Zhao
Department of Neurosurgery, University of Minnesota Medical School, Lions Research Building, Room 421, 2001 Sixth Street S.E, Minneapolis 55455, USA
Brain Res Brain Res Protoc 11:38-45. 2003..Here, we report a simple, effective and reproducible method of tissue preparation and fixation that results in the immunohistochemical labeling of transplanted and host cells... - Sox1 acts through multiple independent pathways to promote neurogenesisLixin Kan
Department of Neurology, Northwestern University s Feinberg School of Medicine, Chicago, IL 60611 3008, USA
Dev Biol 269:580-94. 2004..These observations suggest that Sox1 works through multiple independent pathways to promote neuronal cell fate determination and differentiation... - Tauroursodeoxycholic acid improves the survival and function of nigral transplants in a rat model of Parkinson's diseaseWei-Ming Duan
Department of Neurosurgery, University of Minnesota Medical School, Minneapolis 55455, USA
Cell Transplant 11:195-205. 2002..These data demonstrate that pretreatment of the cell suspension with TUDCA can reduce apoptosis and increase the survival of grafted cells, resulting in an improvement of behavioral recovery... - The role of stem cell factor and granulocyte-colony stimulating factor in brain repair during chronic strokeChun Shu Piao
Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130, USA
J Cereb Blood Flow Metab 29:759-70. 2009..These data suggest that SCF+G-CSF treatment can enhance repair of brain damage during chronic stroke by mobilizing BMSCs, and promoting the contribution of bone marrow-derived cells to angiogenesis and neurogenesis... - Postischemic exercise attenuates whereas enriched environment has certain enhancing effects on lesion-induced subventricular zone activation in the adult ratMila Komitova
The Arvid Carlsson Institute at the Institute of Clinical Neuroscience, Medicinaregatan 11, Box 432, 405 30 Goteborg, Sweden
Eur J Neurosci 21:2397-405. 2005..It may be concluded that in contrast to enriched environment, exercise during the first postischemic week might be detrimental for regenerative processes initiated in the SVZ after stroke...