Research Topics
Genomes and Genes | Guohong LiSummaryAffiliation: Louisiana State University Health Sciences Center Country: USA Publications
Research Grants
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Detail Information
Publications
Periostin mediates vascular smooth muscle cell migration through the integrins alphavbeta3 and alphavbeta5 and focal adhesion kinase (FAK) pathwayGuohong Li
Department of Neurosurgery, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA, United States
Atherosclerosis 208:358-65. 2010..These results reveal a mechanism whereby PN mediates vascular SMC migration through an interaction with alphaV-integrins (mainly alphanubeta3) and subsequent activation of FAK pathway...
Crucial role of CD40 signaling in vascular wall cells in neointimal formation and vascular remodeling after vascular interventionsZifang Song
Department of Neurosurgery, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA
Arterioscler Thromb Vasc Biol 32:50-64. 2012..Because CD40 and TRAF6 are expressed not only in leukocytes but also in vascular cells, we examined the role of CD40 contributed by vascular wall cells in neointimal formation after carotid ligation in an atherogenic environment...
CD40 is essential in the upregulation of TRAF proteins and NF-kappaB-dependent proinflammatory gene expression after arterial injuryZifang Song
Vascular Biology and Stroke Research Laboratory, Department of Neurosurgery, LSU Health Science Center in Shreveport, Shreveport, Louisiana, United States of America
PLoS ONE 6:e23239. 2011..Our findings firmly established the role for CD40 in neointima formation in 2 distinct injury models...
Phosphatidylinositol-3-kinase gamma plays a central role in blood-brain barrier dysfunction in acute experimental strokeRong Jin
Department of Neurosurgery, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA 71130, USA
Stroke 42:2033-44. 2011..This study was conducted to investigate the role of the PI3K? in the blood-brain barrier dysfunction and brain damage induced by focal cerebral ischemia/reperfusion...
Role of specific microRNAs in regulation of vascular smooth muscle cell differentiation and the response to injuryZifang Song
Department of Neurosurgery, LSU Health Science Center, Shreveport, LA, USA
J Cardiovasc Transl Res 3:246-50. 2010..Here, we review recent advance regarding functions of specific miRNAs in vasculature and discuss possible mechanisms by which miRNAs modulate proliferation and differentiation of VSMCs...
Phosphoinositide 3-kinase-gamma expression is upregulated in brain microglia and contributes to ischemia-induced microglial activation in acute experimental strokeRong Jin
Department of Neurosurgery, Vascular Biology and Stroke Research Laboratory, Louisiana State University Health Sciences Center, Shreveport, LA, USA
Biochem Biophys Res Commun 399:458-64. 2010..The results suggest that PI3Kgamma is an ischemia-responsive gene in brain microglia and contributes to ischemia-induced microglial activation and expansion...
MicroRNA expression and function in cardiac ischemic injuryShiyong Yu
Department of Neurosurgery, LSU Health Science Center, Shreveport, LA 71130, USA
J Cardiovasc Transl Res 3:241-5. 2010....
Research Grants
- Mechanisms of CD40/CD40L in vascular injury and repairGuohong Li; Fiscal Year: 2010..The results obtained will provide novel insights into the mechanisms of restenosis and promise to provide valuable information for the development of novel therapeutic strategies to prevent and treat vascular disease in humans. ..
