Research Topics
| M J MessinaSummaryAffiliation: Loma Linda University Country: USA Publications
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Publications
Insights gained from 20 years of soy researchMark Messina
Department of Nutrition, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA
J Nutr 140:2289S-2295S. 2010..Finally, other than allergic reactions, there is almost no credible evidence to suggest traditional soyfoods exert clinically relevant adverse effects in healthy individuals when consumed in amounts consistent with Asian intake...- An overview of the health effects of isoflavones with an emphasis on prostate cancer risk and prostate-specific antigen levelsMark Messina
Loma Linda University, School of Public Health, Department of Nutrition, Loma Linda, CA 92350, USA
J AOAC Int 89:1121-34. 2006.... - The role of soy in vegetarian dietsMark Messina
Department of Nutrition, School of Public Health, Loma Linda University, Loma Linda, California, USA
Nutrients 2:855-88. 2010..Based on the soy intake associated with health benefits in the epidemiologic studies and the benefits noted in clinical trials, optimal adult soy intake would appear to be between two and four servings per day... - Estimated Asian adult soy protein and isoflavone intakesMark Messina
Department ofNutrition, School of PublicHealth, Loma Linda University, Loma Linda, CA, USA
Nutr Cancer 55:1-12. 2006..Evidence suggests that < or =10% of the Asian population consumes as much as 25 g of soy protein or 100 mg of isoflavones per day. The applicability of these findings for making soy intake recommendations for non-Asians is discussed... - Addressing the soy and breast cancer relationship: review, commentary, and workshop proceedingsMark Messina
Department of Nutrition, School of Public Health, Loma Linda University, Loma Linda, CA, USA
J Natl Cancer Inst 98:1275-84. 2006..This paper summarizes the workshop findings and recommendations. The primary research recommendation is that the impact of isoflavones on breast tissue needs to be evaluated at the cellular level in women at high risk for breast cancer... - Soy isoflavones, estrogen therapy, and breast cancer risk: analysis and commentaryMark J Messina
Nutrition Matters, Inc, 439 Calhoun Street, Port Townsend, WA 98368, USA
Nutr J 7:17. 2008.... - The endometrial effects of isoflavones: a discussion paperMark Messina
Complement Ther Clin Pract 14:212-4. 2008 - Investigating the optimal soy protein and isoflavone intakes for women: a perspectiveMark Messina
Department of Nutrition, School of Public Health, Loma Linda University, Loma Linda, CA, USA
Womens Health (Lond Engl) 4:337-56. 2008..In addition, an intake of 25 g/day soy protein can be specifically used as the recommendation for cholesterol reduction... - Perspectives on the soy-breast cancer relationMark Messina
Department of Nutrition, School of Public, Health, Loma Linda University, Loma Linda, CA, USA
Am J Clin Nutr 89:1673S-1679S. 2009.... - Early intake appears to be the key to the proposed protective effects of soy intake against breast cancerMark Messina
Loma Linda University, Loma Linda, California, USA
Nutr Cancer 61:792-8. 2009.... - Soybean isoflavone exposure does not have feminizing effects on men: a critical examination of the clinical evidenceMark Messina
Department of Nutrition, School of Public Health, Loma Linda University, Loma Linda, California 92350, USA
Fertil Steril 93:2095-104. 2010..To critically evaluate the clinical evidence, and when not available, the animal data, most relevant to concerns that isoflavone exposure in the form of supplements or soy foods has feminizing effects on men... - A brief historical overview of the past two decades of soy and isoflavone researchMark Messina
Department of Nutrition, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA
J Nutr 140:1350S-4S. 2010..More recently, in vitro and animal research has raised questions about the safety of isoflavone exposure for certain subsets of the population, although the human data are largely inconsistent with these concerns... - Effects of soy protein and soybean isoflavones on thyroid function in healthy adults and hypothyroid patients: a review of the relevant literatureMark Messina
Department of Nutrition, School of Public Health, Loma Linda University, California, USA
Thyroid 16:249-58. 2006..Therefore, it is important for soy food consumers to make sure their intake of iodine is adequate... - Legumes and soybeans: overview of their nutritional profiles and health effectsM J Messina
Nutrition Matters, Inc, Townsend, WA 98368, USA
Am J Clin Nutr 70:439S-450S. 1999..Given the nutrient profile and phytochemical contribution of beans, nutritionists should make a concerted effort to encourage the public to consume more beans in general and more soyfoods in particular... - Efficacy of soyfoods and soybean isoflavone supplements for alleviating menopausal symptoms is positively related to initial hot flush frequencyMark Messina
Department of Nutrition, Loma Linda University, Loma Linda, CA 92350, USA
J Med Food 6:1-11. 2003.... - Gaining insight into the health effects of soy but a long way still to go: commentary on the fourth International Symposium on the Role of Soy in Preventing and Treating Chronic DiseaseMark Messina
Nutrition Matters, Inc, Port Townsend, WA 98368, USA
J Nutr 132:547S-551S. 2002..If this modest amount of soy protein were to be incorporated in the American diet, it would represent only approximately 15% of total U. S. protein intake... - Skeletal benefits of soy isoflavones: a review of the clinical trial and epidemiologic dataMark Messina
Department of Nutrition, School of Public Health, Loma Linda University, Loma Linda, California, USA
Curr Opin Clin Nutr Metab Care 7:649-58. 2004..The purpose of this review is to evaluate the clinical and epidemiologic studies relevant to the hypothesis that isoflavones promote bone health... - Soy for breast cancer survivors: a critical review of the literatureM J Messina
Nutrition Matters, Inc, Port Townsend, WA 98368, USA
J Nutr 131:3095S-108S. 2001..Consequently, if breast cancer patients enjoy soy products, it seems reasonable for them to continue to use them... - Introduction to and perspectives from the Fifth International Symposium on the Role of Soy in Preventing and Treating Chronic DiseaseMark Messina
Nutrition Matters, Inc, Port Townsend, WA 98368, USA
J Nutr 134:1205S-1206S. 2004 - Report on the 8th International Symposium on the Role of Soy in Health Promotion and Chronic Disease Prevention and TreatmentMark Messina
Nutrition Matters, Port Townsend, WA 98368, USA
J Nutr 139:796S-802S. 2009..The majority of presentations at the Tokyo symposium focused on isoflavones. In this article, the major findings presented at the symposium are highlighted, and commentary about those findings and related background is provided... - Effect of two types of soy milk and dairy milk on plasma lipids in hypercholesterolemic adults: a randomized trialChristopher D Gardner
Stanford Prevention Research Center, Department of Medicine, Stanford University Medical School, Stanford, CA, USA
J Am Coll Nutr 26:669-77. 2007..To compare the effects of two commercially available soy milks (one made using whole soy beans, the other using soy protein isolate) with low-fat dairy milk on plasma lipid, insulin, and glucose responses... - Introduction and satellite session at the fourth International Symposium on the Role of Soy in Preventing and Treating Chronic DiseaseStephen Barnes
Department of Pharmacology and Toxicology, University of Alabama at Birmingham, AL 35294, USA
J Nutr 132:545S-546S. 2002 - Isoflavone supplements do not affect thyroid function in iodine-replete postmenopausal womenBonnie Bruce
Division of Immunology and Rheumatology, Department of Medicine, Stanford University, Palo Alto, CA 94304, USA
J Med Food 6:309-16. 2003..These results indicate that in this group of healthy iodine-replete subjects, soy isoflavones do not adversely affect thyroid function... - Not all soy products are created equal: caution needed in interpretation of research resultsJohn W Erdman
Department of Food Science and Human Nutrition, University of Illinois, Urbana, IL 61801, USA
J Nutr 134:1229S-1233S. 2004..Efforts are needed by all to reduce the public confusion by adapting standardized approaches to the reporting of data. This paper provides a framework for both standardization of nomenclature and appropriate interpretation of data... - Conclusion that isoflavones exert estrogenic effects on breast tissue and may raise breast cancer risk unfoundedMark Messina
Mol Nutr Food Res 52:299-300. 2008 - The safety and benefits of soybean isoflavones. A natural alternative to conventional hormone therapy?Mark Messina
Menopause 14:958; author reply 958-9. 2007 - Western soy intake is too low to produce health effectsMark Messina
Am J Clin Nutr 80:528-9; author reply 529-30. 2004 - Hypoglycemic effects of isoflavones unprovenMark Messina
J Womens Health (Larchmt) 14:468-9; author reply 470. 2005 - Resolving the soy-breast cancer controversyMark Messina
J Am Diet Assoc 106:363-4. 2006 - Effect of soy protein on testosterone levelsMark Messina
Cancer Epidemiol Biomarkers Prev 16:2795; author reply 2795-6. 2007 - Soy, garlic, and ginkgo biloba: their potential role in cardiovascular disease prevention and treatmentChristopher D Gardner
Stanford Center for Research in Disease Prevention, Stanford University Medical School, 730 Welch Road, Suite B, Palo Alto, CA 94304 1583, USA
Curr Atheroscler Rep 5:468-75. 2003..And for each there is at least some level of disagreement or controversy. The focus of this review is on results from recent human clinical trials... - Protein and legume intake and prostate cancer mortality in Puerto Rican menEllen Smit
School of Community Health, Portland State University, Portland, OR 97201, USA
Nutr Cancer 58:146-52. 2007..Thus, we find no association between legumes or protein intake and prostate cancer mortality in this longitudinal cohort study of PR men... - Need to establish threshold soy protein intake for cholesterol reductionMark Messina
Am J Clin Nutr 81:942-3. 2005