Research Topics
| Gary FraserSummaryAffiliation: Loma Linda University Country: USA Publications
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Publications
Vegetarian diets: what do we know of their effects on common chronic diseases?Gary E Fraser
Department of Epidemiology and Biostatistics, Loma Linda University, Loma Linda, CA, USA
Am J Clin Nutr 89:1607S-1612S. 2009..Although vegetarian diets are healthful and are associated with lower risk of several chronic diseases, different types of vegetarians may not experience the same effects on health...
Reliability of serum and urinary isoflavone estimatesGary E Fraser
Department of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA
Biomarkers 15:135-9. 2010..These results suggest that fasting morning serum isoflavone estimates will provide a poor index of long-term soy intake, but that overnight urinary estimates perform much better...
Regression calibration when foods (measured with error) are the variables of interest: markedly non-Gaussian data with many zeroesGary E Fraser
Department of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, California, USA
Am J Epidemiol 175:325-31. 2012..Irrespective of fit, linear regression calibration in this situation at least approximately corrects bias. More complex linear calibration equations that improve fit may increase power over that of uncalibrated regressions...
Validation of self-reported anthropometrics in the Adventist Health Study 2Maira Bes-Rastrollo
Dept of Preventive Medicine and Public Health, School of Medicine, University of Navarra, Pamplona, Spain
BMC Public Health 11:213. 2011..The objective of this study was to evaluate the validity of self-reported anthropometrics in the Adventist Health Study 2 (AHS-2)...
Missing data in a long food frequency questionnaire: are imputed zeroes correct?Gary E Fraser
Department of Epidemiology and Biostatistics, Loma Linda University, Loma Linda, CA, USA
Epidemiology 20:289-94. 2009..Missing data are a common problem in nutritional epidemiology. Little is known of the characteristics of these missing data, which makes it difficult to conduct appropriate imputation...
A multivariate method for measurement error correction using pairs of concentration biomarkersGary E Fraser
Department of Adventist Health Study 2, Loma Linda University, Loma Linda, CA 92350, USA
Ann Epidemiol 17:64-73. 2007..Measurement error is a pervasive problem in behavioral epidemiology, and available methods of correction all have generally untenable assumptions. We propose a multivariate method with more realistic assumptions...
Guided multiple imputation of missing data: using a subsample to strengthen the missing-at-random assumptionGary Fraser
Loma Linda University, Loma Linda, California, USA
Epidemiology 18:246-52. 2007....
Comparing self-reported disease outcomes, diet, and lifestyles in a national cohort of black and white Seventh-day AdventistsSusanne Montgomery
Loma Linda University, School of Public Health, 1709 Nichol Hall, Loma Linda, CA 92373, USA
Prev Chronic Dis 4:A62. 2007..This paper focuses on some preliminary baseline analyses of responses from the first group of participants recruited for AHS-2...
Foods and food groups associated with the incidence of colorectal polyps: the Adventist Health StudyYessenia M Tantamango
Department of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, Loma Linda, California 92350, USA
Nutr Cancer 63:565-72. 2011..These associations showed a dose-response effect. High frequency of consumption of cooked green vegetables, dried fruit, legumes, and brown rice was associated with a decreased risk of colorectal polyps...
The contribution of soul and Caribbean foods to nutrient intake in a sample of Blacks of US and Caribbean descent in the Adventist Health Study-2: a pilot studyJabar A Akbar
School of Public Health, Dept of Health Services, University of California, Los Angeles, California, USA
Ethn Dis 17:244-9. 2007..To evaluate the dietary contribution of culturally preferred foods in a population of Black Seventh-Day Adventists from the eastern and southern United States in order to improve the standard food frequency questionnaire...
Effects of meat consumption and vegetarian diet on risk of wrist fracture over 25 years in a cohort of peri- and postmenopausal womenDonna L Thorpe
Department of Physical Therapy, School of Allied Health Professions, Loma Linda University, Loma Linda, CA 92350, USA
Public Health Nutr 11:564-72. 2008..However, other studies have raised a question regarding the adequacy of protein in such a diet...
Feasibility of running clinics to collect biological specimens in a nationwide cohort study--Adventist Health Study-2Jacqueline Chan
Department of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA
Ann Epidemiol 17:454-7. 2007..Therefore, the feasibility of collecting biological specimens from a nationally dispersed cohort (Adventist Health Study-2) was tested...
Cohort profile: The Adventist Health Study-2 (AHS-2)Terry L Butler
School of Public Health, Loma Linda University, Loma Linda, California 9235, USA
Int J Epidemiol 37:260-5. 2008
Regional differences in attitudes that may affect health behavior and willingness to participate in research among Black Seventh-day AdventistsAndy Lampkin
School of Religion, Loma Linda, California, USA
Ethn Dis 19:439-46. 2009..To identify the attitudes and perceptions of Black Seventh-day Adventists regarding health research and the healthcare system in two regions of the United States...
Validation of soy protein estimates from a food-frequency questionnaire with repeated 24-h recalls and isoflavonoid excretion in overnight urine in a Western population with a wide range of soy intakesKaren Jaceldo-Siegl
Adventist Health Study 2, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA
Am J Clin Nutr 87:1422-7. 2008..Evidence of the benefits of soy on cancer risk in Western populations is inconsistent, in part because of the low intake of soy in these groups...
Serum 25-hydroxyvitamin D status of vegetarians, partial vegetarians, and nonvegetarians: the Adventist Health Study-2Jacqueline Chan
Adventist Health Study 2, School of Public Health, Loma Linda University Loma Linda, CA, USA
Am J Clin Nutr 89:1686S-1692S. 2009....
Type of vegetarian diet, body weight, and prevalence of type 2 diabetesSerena Tonstad
Department of Health Promotion and Education, School of Public Health, Loma Linda University, Loma Linda, California, USA
Diabetes Care 32:791-6. 2009..We assessed the prevalence of type 2 diabetes in people following different types of vegetarian diets compared with that in nonvegetarians...
Validation of nutrient intake using an FFQ and repeated 24 h recalls in black and white subjects of the Adventist Health Study-2 (AHS-2)Karen Jaceldo-Siegl
Department of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA
Public Health Nutr 13:812-9. 2010..To validate a 204-item quantitative FFQ for measurement of nutrient intake in the Adventist Health Study-2 (AHS-2)...
Determinants of serum 25 hydroxyvitamin D levels in a nationwide cohort of blacks and non-Hispanic whitesJacqueline Chan
Department of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, 24785 Stewart St, Loma Linda, CA 92350, USA
Cancer Causes Control 21:501-11. 2010..This will allow a regression calibration approach to determine s25(OH)D levels replacing the more costly method of collection and analysis of blood samples...
Traumatic experiences, major life stressors, and self-reporting a physician-given fibromyalgia diagnosisMark G Haviland
Department of Psychiatry, Loma Linda University School of Medicine, Loma Linda, CA, USA
Psychiatry Res 177:335-41. 2010..We recommend that researchers investigate the relationship between stress and fibromyalgia in concert with genetic and biomarker studies...
Correlates of perceived pain-related restrictions among women with fibromyalgiaPeter Przekop
Department of Psychiatry, Loma Linda University School of Medicine, Loma Linda, California 92350, USA
Pain Med 11:1698-706. 2010..To identify correlates of perceived pain-related restrictions in a community sample of women with fibromyalgia...
Recruiting black Americans in a large cohort study: the Adventist Health Study-2 (AHS-2) design, methods and participant characteristicsR Patti Herring
Department of Health Promotion and Education, Loma Linda University, School of Public Health, 24951 North Circle Drive, Nichol Hall 1410, Loma Linda, CA 92350, USA
Ethn Dis 20:437-43. 2010..This paper describes the study design, recruitment methods, response rates, and characteristics of Blacks in the AHS-2, thus providing insights about effective strategies to recruit Blacks to participate in research studies...
The effect of vigorous physical activity and risk of wrist fracture over 25 years in a low-risk survivor cohortDonna L Thorpe
Department of Physical Therapy, School of Allied Health Professions, Loma Linda University, Loma Linda, CA 92350, USA
J Bone Miner Metab 24:476-83. 2006..61; 95% CI, 0.43, 0.87). In this cohort of women with a relatively low incidence of wrist fracture, higher levels of physical activity at baseline were protective against risk of fracture during 25 years of follow-up...
A search for truth in dietary epidemiologyGary E Fraser
Department of Epidemiology and Biostatistics, Loma Linda University, Loma Linda, CA 92350, USA
Am J Clin Nutr 78:521S-525S. 2003..Regression calibration methods that use carefully selected biological surrogates (correlates) of the dietary factor of interest in the calibration study seem to use more realistic assumptions...
Water, other fluids, and fatal coronary heart disease: the Adventist Health StudyJacqueline Chan
Adventist Health Studies, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA
Am J Epidemiol 155:827-33. 2002..Fluid intake as a putative coronary heart disease risk factor may deserve further consideration in other populations or using other study designs...
Effect on body weight of a free 76 Kilojoule (320 calorie) daily supplement of almonds for six monthsGary E Fraser
Center for Health Research, School of Public Health, Loma Linda University, California 92350, USA
J Am Coll Nutr 21:275-83. 2002..We tested the hypothesis that a free daily supplement (averaging 76 kJ) of almonds for six months, with no dietary advice, would not change body weight...
Comparison of adipose tissue fatty acids with dietary fatty acids as measured by 24-hour recall and food frequency questionnaire in Black and White Adventists: the Adventist Health StudySynnøve F Knutsen
Department of Epidemiology and Biostatistics, Loma Linda University School of Public Health, CA 92350, USA
Ann Epidemiol 13:119-27. 2003..The FFQ was specially designed for use in a cohort of Seventh-day Adventists. In preparation for a large cohort study investigating the effect of diet on risk of colon, prostate and breast cancer...
Does low meat consumption increase life expectancy in humans?Pramil N Singh
Department of Epidemiology and Biostatistics, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA
Am J Clin Nutr 78:526S-532S. 2003..Since meat products represent a major source of protein in the Western diet, findings on whether meat intake significantly contributes to the burden of fatal disease have important clinical and public health implications...
Correlations between estimated and true dietary intakesGary E Fraser
Center for Health Research, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA
Ann Epidemiol 14:287-95. 2004..It is unclear how well questionnaire or so-called reference methods of dietary assessment correlate with true dietary intake. We develop a method to estimate such correlations...
Long-term almond supplementation without advice on food replacement induces favourable nutrient modifications to the habitual diets of free-living individualsKaren Jaceldo-Siegl
Department of Nutrition, School of Public Health, Loma Linda University, CA 92350, USA
Br J Nutr 92:533-40. 2004..A daily supplement of almonds can induce favourable nutrient modifications for chronic disease prevention to an individual's habitual diet...
Correlations between estimated and true dietary intakes: using two instrumental variablesGary E Fraser
Department of Epidemiology and Biostatistics, Loma Linda University, Loma Linda, CA 92313, USA
Ann Epidemiol 15:509-18. 2005..We describe a new application of the method of triads that allows an estimate of the correlation between a dietary questionnaire measure (Q) and true intake (T)...
Recruiting blacks to the Adventist health study: Do follow-up phone calls increase response rates?La Shawnta Bell
Loma Linda University School of Public Health, Loma Linda, CA 92350, USA
Ann Epidemiol 15:667-72. 2005..This difference in response by ethnic group was statistically significant (p < 0.01). CONCLUSION: Follow-up phone calls improved response rates among black subjects only...
Dietary risk factors for ovarian cancer: the Adventist Health Study (United States)Fatemeh Kiani
Department of Epidemiology and Biostatistics, Loma Linda University, Loma Linda, CA, 92350, USA
Cancer Causes Control 17:137-46. 2006..002), and also with higher fruit consumption (p < 0.01). A weak protective association was found with low fat, but not whole milk. Little confounding was observed between these foods...
Understanding the challenges in recruiting blacks to a longitudinal cohort study: the Adventist health studyPatti Herring
Department of Health Promotion and Education, Loma Linda University School of Public Health, Loma Linda, California, USA
Ethn Dis 14:423-30. 2004....
Commentary: Protection from stroke by eating animal foods? Surely not!Gary Fraser
Loma Linda University, Loma Linda, CA 92350, USA
Int J Epidemiol 32:543-5. 2003
Dietary fiber and risk of coronary heart disease: a pooled analysis of cohort studiesMark A Pereira
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN55454, USA
Arch Intern Med 164:370-6. 2004..The purpose of this study was to conduct a pooled analysis of dietary fiber and its subtypes and risk of coronary heart disease...
A pooled analysis of 12 cohort studies of dietary fat, cholesterol and egg intake and ovarian cancerJeanine M Genkinger
Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
Cancer Causes Control 17:273-85. 2006..Results for histologic subtypes were similar. Overall, fat, cholesterol and egg intakes were not associated with ovarian cancer risk. The positive association for saturated fat intake at very high intakes merits further investigation...
Dairy products and ovarian cancer: a pooled analysis of 12 cohort studiesJeanine M Genkinger
Department of Nutrition, Harvard School of Public Health, Room 339, Building 2, 665 Huntington Avenue, Boston, Massachusetts 02115, USA
Cancer Epidemiol Biomarkers Prev 15:364-72. 2006..Although case-control studies have reported conflicting results for dairy foods and lactose, several cohort studies have shown positive associations between skim milk, lactose, and ovarian cancer...
Intakes of vitamins A, C and E and folate and multivitamins and lung cancer: a pooled analysis of 8 prospective studiesEunyoung Cho
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Int J Cancer 118:970-8. 2006..The results generally did not differ across studies or by sex, smoking habits and lung cancer cell type. In conclusion, these data do not support the hypothesis that intakes of vitamins A, C and E and folate reduce lung cancer risk...
Fruits, vegetables and lung cancer: a pooled analysis of cohort studiesStephanie A Smith-Warner
Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
Int J Cancer 107:1001-11. 2003..However, we cannot rule out the possibility that our results are due to residual confounding by smoking. The primary focus for reducing lung cancer incidence should continue to be smoking prevention and cessation...
A cohort study found that earlier and longer Seventh-day Adventist church membership was associated with reduced male mortalityIvar Heuch
Department of Mathematics, University of Bergen, Johannes Bruns Gate 12, N 5008 Bergen, Norway
J Clin Epidemiol 58:83-91. 2005..The purpose of this study was to estimate relative mortality rates among persons joining the church in adult life compared with members of the same age who joined in childhood...
Dairy foods, calcium, and colorectal cancer: a pooled analysis of 10 cohort studiesEunyoung Cho
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
J Natl Cancer Inst 96:1015-22. 2004..Studies in animals have suggested that calcium may reduce the risk of colorectal cancer. However, results from epidemiologic studies of intake of calcium or dairy foods and colorectal cancer risk have been inconclusive...
Meat and dairy food consumption and breast cancer: a pooled analysis of cohort studiesStacey A Missmer
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115 6096, USA
Int J Epidemiol 31:78-85. 2002..Our objective was to evaluate the risk of breast cancer associated with meat and dairy food consumption and to assess whether non-dietary risk factors modify the relation...
Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohortsPaul Knekt
National Public Health Institute, Helsinki, Finland
Am J Clin Nutr 80:1508-20. 2004..Epidemiologic studies have suggested a lower risk of coronary heart disease (CHD) at higher intakes of fruit, vegetables, and whole grain. Whether this association is due to antioxidant vitamins or some other factors remains unclear...
Height, body mass index, and ovarian cancer: a pooled analysis of 12 cohort studiesLeo J Schouten
Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, The Netherlands
Cancer Epidemiol Biomarkers Prev 17:902-12. 2008..Although many studies have investigated the association between anthropometry and ovarian cancer risk, results have been inconsistent...
Black art posters, an incentive to increase study enrollment among Blacks in a large cohort studyAntronette K Yancey
Department of Health Services, UCLA School of Public Health, Los Angeles, CA 90095, USA
Prev Med 46:370-3. 2008..Black art posters were offered to replace or augment the established $10 incentive for questionnaire completion in a longitudinal cohort study...
Fruits, vegetables, and colon cancer risk in a pooled analysis of 14 cohort studiesAnita Koushik
Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
J Natl Cancer Inst 99:1471-83. 2007..Statistical power to examine associations by colon site has been limited in previous studies...
Fruits and vegetables and ovarian cancer risk in a pooled analysis of 12 cohort studiesAnita Koushik
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 14:2160-7. 2005..Associations for total fruits and vegetables were similar for different histologic types. These results suggest that fruit and vegetable consumption in adulthood has no important association with the risk of ovarian cancer...
Dietary fat and risk of lung cancer in a pooled analysis of prospective studiesStephanie A Smith-Warner
Harvard School of Public Health, Department of Nutrition, Boston, Massachusetts 02115, USA
Cancer Epidemiol Biomarkers Prev 11:987-92. 2002..These data do not support an important relation between fat or cholesterol intakes and lung cancer risk. The means to prevent this important disease remains avoidance of smoking...
Specificity in dietary population researchGary E Fraser
Ann Epidemiol 17:208. 2007
Research Grants
- CANCER EPIDEMIOLOGY IN ADVENTISTS--A LOW RISK GROUPGary Fraser; Fiscal Year: 2007..S. and Canada from a uniquely informative population. As originally planned it is during the coming Years 06-10 that this outstanding resource will provide answers to the questions posed. ..
- Biological and Psychosocial Manifestations of ReligionGary Fraser; Fiscal Year: 2007..This study should further current understanding of how various manifestations of religion positively and negatively affect physical and mental health. ..
- CANCER EPIDEMIOLOGY IN ADVENTISTS--A LOW RISK GROUPGary Fraser; Fiscal Year: 2006..This larger study will provide much greater statistical power, more accurate and documented exposure assessment, and will also include a large cohort of black Adventists. ..
- CANCER EPIDEMIOLOGY IN ADVENTISTS--A LOW RISK GROUPGary Fraser; Fiscal Year: 2005..This larger study will provide much greater statistical power, more accurate and documented exposure assessment, and will also include a large cohort of black Adventists. ..
