Research Topics
| Yohan KimSummaryAffiliation: La Jolla Institute for Allergy and Immunology Country: USA Publications
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Detail Information
Publications
Peptide binding predictions for HLA DR, DP and DQ moleculesPeng Wang
La Jolla Institute for Allergy and Immunology, La Jolla, USA
BMC Bioinformatics 11:568. 2010..This reflects a significant gap in knowledge as HLA DP and DQ molecules are presumably equally important, and have only been studied less because they are more difficult to handle experimentally...- Derivation of an amino acid similarity matrix for peptide: MHC binding and its application as a Bayesian priorYohan Kim
Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, USA
BMC Bioinformatics 10:394. 2009..Our aim is to quantify this measure of similarity to improve peptide:MHC binding prediction methods. This should help compensate for holes and bias in the sequence space coverage of existing peptide binding datasets... - Locally defined protein phylogenetic profiles reveal previously missed protein interactions and functional relationshipsYohan Kim
Department of Chemistry and Biochemistry, University of California at San Diego, La Jolla, California 92093-0505, USA
Proteins 62:1115-24. 2006..Thus, the Multiple-Profile method can be used with other methods to determine functional relationships on a genome scale with wider coverage... - Towards defining molecular determinants recognized by adaptive immunity in allergic disease: an inventory of the available dataKerrie Vaughan
The Immune Epitope Database IEDB, La Jolla Institute for Allergy and Immunology LIAI, La Jolla, CA 92037, USA
J Allergy (Cairo) 2010:628026. 2010..Finally, our analysis also underscores that only a handful of epitopes have thus far been investigated for their immunotherapeutic potential... - Immune epitope database analysis resource (IEDB-AR)Qing Zhang
Immune Epitope Database and Analysis Resource IEDB AR, La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA
Nucleic Acids Res 36:W513-8. 2008..New functionalities have been added to most of the previously implemented tools, and a total of eight new tools were added, including two B-cell epitope prediction tools, four T-cell epitope prediction tools and two analysis tools... - Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human populationJason A Greenbaum
Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA
Proc Natl Acad Sci U S A 106:20365-70. 2009..These results are consistent with reports about disease incidence, severity, and mortality rates associated with human S-OIV... - Definition of epitopes and antigens recognized by vaccinia specific immune responses: their conservation in variola virus sequences, and use as a model system to study complex pathogensAlessandro Sette
Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA
Vaccine 27:G21-6. 2009..Finally, we find that the vast majority of VACV epitopes are conserved in variola virus (VARV), thus suggesting that the epitopes defined herein also have relevance for the efficacy of VACV as a smallpox vaccine... - Applications for T-cell epitope queries and tools in the Immune Epitope Database and Analysis ResourceYohan Kim
La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA
J Immunol Methods 374:62-9. 2011..We address common questions and concerns faced by users, and identify patterns of usage that have proven successful... - Inferring functional information from domain co-evolutionYohan Kim
Department of Chemistry and Biochemistry, University of California at San Diego, La Jolla, CA 92093, USA
Bioinformatics 22:40-9. 2006..Furthermore, co-evolving regions of proteins detected by our method enable us to make hypotheses about their specific functions, many of which are supported by existing biochemical studies...