Research Topics
| C J DiskinSummaryAffiliation: Kathleen D. Schaum and Associates Country: USA Publications
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Detail Information
Publications
Does the hyperfiltration of minoxidil result in increased proteinuria and loss of renoprotection conferred by angiotensin inhibition?Charles J Diskin
HNDT, Auburn University, Opelika, AL 36801, USA
Kidney Blood Press Res 29:54-9. 2006....
Will the addition of pentoxifylline reduce proteinuria in patients with diabetic glomerulosclerosis refractory to maximal doses of both an angiotensin-converting enzyme inhibitor and an angiotensin receptor blocker?Charles J Diskin
Hypertension, Nephrology, Dialysis and Transplantation Clinic, Auburn University, Opelika, AL 36801, USA
J Nephrol 20:410-6. 2007....
Beyond anemia: the clinical impact of the physiologic effects of erythropoietinCharles J Diskin
Department of Hypertension, Nephrology, Dialysis and Transplantation, Auburn University, Opelika, Alabama 36801, USA
Semin Dial 21:447-54. 2008..We will review what is known about the physiology of this plasma factor that, it is now clear, is more than just an erythrocyte production factor...
Removal of methotrexate by peritoneal dialysis and hemodialysis in a single patient with end-stage renal diseaseCharles J Diskin
HNDT, Auburn University, Opelika, Alabama 36801, USA
Am J Med Sci 332:156-8. 2006..Measurements of total methotrexate levels were made before, during, and after sequential peritoneal and hemodialysis treatments...
Can acidosis and hyperphosphataemia result in increased erythropoietin dosing in haemodialysis patients?Charles J Diskin
Hypertension, Nephrology, Dialysis and Transplantation Clinic, Auburn University, Opelika, Alabama 36801, USA
Nephrology (Carlton) 11:394-9. 2006....
Acute renal failure due to a primary renal B-cell lymphomaCharles J Diskin
Hypertension, Nephrology, Dialysis and Transplantation Clinic, Auburn University
Am J Kidney Dis 50:885-9. 2007
Gustatory sweating recurring on peritoneal dialysis but resolving during periods of hemodialysisCharles J Diskin
Hypertension, Nephrology, Dialysis and Transplantation Clinic, Auburn University, Opelika, Alabama 36801, USA
Hemodial Int 12:230-2. 2008..Treatment with topical glycopyrrolate may be safe and effective given every third day if clonidine is ineffective...
Effect of phosphate binders upon TSH and L-thyroxine dose in patients on thyroid replacementCharles J Diskin
Department of Hypertension, Nephrology, Dialysis, Transplantation, Auburn University, Opelika, AL 36801, USA
Int Urol Nephrol 39:599-602. 2007....
Creatinine and glomerular filtration rate: evolution of an accommodationCharles J Diskin
Hypertension, Nephrology, Dialysis, and Transplantation Clinic, Auburn University, Building 21, 121 N 20th Street, Opelika, AL 36801, USA
Ann Clin Biochem 44:16-9. 2007....
Is systemic heparin a risk factor for catheter-related sepsis in dialysis patients? An evaluation of various biofilm and traditional risk factorsCharles J Diskin
Auburn University, Opelika, Ala 36801, USA
Nephron Clin Pract 107:c128-32. 2007..Intravenous iron and heparin are thought to promote the formation of biofilm. Both are commonly employed during hemodialysis treatments which might affect the incidence of catheter-related sepsis...
The role of the nephrologist in the treatment of lupus nephritisCharles J Diskin
Hypertension, Nephrology, Dialysis, and Transplantation Clinic, Auburn University, Opelika, AL 36801, USA
Nat Clin Pract Nephrol 3:E1. 2007
Malignancy-related hypercalcemia developing on a bisphosphonate but responding to calcitoninCharles J Diskin
Auburn University, Opelika, AL 36801, USA
Clin Lung Cancer 8:434-5. 2007..Intravenous calcitonin produced a dramatic decrease within 12 hours and normal serum calcium within 24 hours of treatment. Calcitonin might be useful for hypercalcemia of malignancy resistant to bisphosphonates...
Recurrent metabolic alkalosis and elevated troponins after crack cocaine use in a hemodialysis patientCharles J Diskin
HNDT, Auburn University, Bldg 21, 121 N 20th Street, Opelika, AL 36801, USA
Clin Exp Nephrol 10:156-8. 2006..The metabolic alkalosis did not recur after counseling and abstention from cocaine...
Understanding the pathophysiology of hemodialysis access problems as a prelude to developing innovative therapiesCharles J Diskin
Hypertension, Nephrology, Dialysis and Transplantation Clinic, Auburn University, Opelika, AL 36801, USA
Nat Clin Pract Nephrol 4:628-38. 2008..Currently available drugs that interfere with metalloproteinases could prevent the formation of aneurysms, and bacterial quorum sensing offers a promising target for the prevention of biofilm infection in hemodialysis catheters...
The prevalence and meaning of eosinophilia in renal diseases on a nephrology consultation serviceCharles J Diskin
Department of Hypertension, Nephrology, Dialysis and Transplantation, Auburn University, Opelika, AL 36801, USA
Nephrol Dial Transplant 26:2549-58. 2011....
Observe and be guarded: the development and rupture of an abdominal aortic mycotic aneurysm in an afebrile hemodialysis patient with normal angiogram, and CT scan, and sterile blood culturesCharles J Diskin
Auburn University Hypertension, Nephrology, 122 N 20th Street, Opelika, AL 36802, USA
Clin Exp Nephrol 8:388-91. 2004..After a discussion of pathophysiology, we offer some insight into why so few mycotic aneurysms are reported in the hemodialysis population...
Toward the optimal clinical use of the fraction excretion of solutes in oliguric azotemiaCharles J Diskin
Hypertension, Nephrology, Dialysis, and Transplantation Clinic, Auburn University, Opelika, AL 36801, USA
Ren Fail 32:1245-54. 2010..We review the tubular physiology of these solutes and show how the differences in tubular physiology might be exploited to develop a strategy for their optimal clinical use...
The use of new concepts in vascular physiology and pharmacology to improve hemodialysis access outcomesC J Diskin
Departments of Hypertention, Nephrology, Dialysis and Transplantion, Auburn University, Opelika, AL 36801, USA
Minerva Urol Nefrol 62:387-410. 2010..Large prospective randomized studies will be needed to determine the true benefit...
Can the combination of calcium and parathormone levels above K/DOQI guidelines be used as a marker of adynamic bone disease in African Americans?Charles J Diskin
Hypertension, Nephrology, Dialysis and Transplantation Clinic, Auburn University, Bldg 21, 121 N 20th Street, Opelika, AL 36801, USA
Int Urol Nephrol 43:1127-32. 2011..Calcium levels above K/DOQI guidelines therefore may signal a need to stop parathyroid suppression...
Novel insights into the pathobiology of the vascular access - do they translate into improved care?Charles J Diskin
Hypertension, Nephrology, Dialysis and Transplantation, Auburn University, Opelika, Ala, USA
Blood Purif 29:216-29. 2010..Implications for possible future interventions based on these novel concepts are offered, and the significance of improving our understanding of the pathobiology is emphasized...
Recurrent hyponatremia after intrathecal methotrexate not related to antidiuretic hormone: is a natriuretic peptide activated?Charles Diskin
Hypertension, Nephrology, Dialysis and Transplantation Clinic, Auburn University, Opelika, AL 36801, USA
Am J Med Sci 331:37-9. 2006..We speculate that a central nervous system natriuretic peptide may be involved in the pathogenesis of the naturesis following intrathecal methotrexate...
Lessons from single cell organisms: insights into the antimicrobial and toxic effects of peritoneal dialysate basesCharles J Diskin
Department of Hypertension, Nephrology, Dialysis and Transplantation, Auburn University, Opelika, AL 36801, USA
Ther Apher Dial 14:127-35. 2010..While our knowledge base in this area is still evolving, an improved understanding of the biochemical basis of both the antibacterial effect and toxicity of the salts of carboxylic acids in peritoneal dialysate can only prove useful...
Can omeprazole reduce the incidence of hypercalcemia in dialysis patients using calcium containing phosphate binders?Charles J Diskin
Hypertension, Nephrology, Dialysis and Transplantation, Auburn University, Opelika, Alabama 36801, USA
J Nephrol 23:438-43. 2010..We chose to investigate whether the use of omeprazole could reduce the incidence of hypercalcemia in dialysis patients who could not afford expensive non-calciumbased phosphate binders...
de Ketham revisited: a modern-day urine wheelCharles J Diskin
Hypertension, Nephrology, Dialysis and Transplantation Clinic, Auburn University, Opelika, Ala, USA
Med J Aust 189:658-9. 2008..In honour of de Ketham, a modern urine wheel is presented, which may be a useful diagnostic tool for present-day physicians...
A hypothesis: can erythropoietin administration affect the severity of retinopathy in diabetic patients with renal failure?Charles J Diskin
Auburn University, 2609 Village Professional Drive, Opelika, AL 36801, USA
Am J Med Sci 334:260-4. 2007..Therefore, we chose to examine whether severity and progression of diabetic retinopathy has been accelerated by the administration of recombinant erythropoietin to patients with chronic renal failure...
Massive increase in proteinuria after the introduction of midodrine in an elderly patient-a case reportCharles J Diskin
HNDT, Auburn University, Opelika, AL 36801, USA
Nephrol Dial Transplant 21:1988. 2006
Minoxidil use in proteinuric renal diseaseCharles J Diskin
Acta Med Croatica 62:93. 2008
More on case 7-2006Charles J Diskin
N Engl J Med 355:1502-3; author reply 1503. 2006
Heparin and biofilm: is this the risk factor for catheter-related sepsis?Charles J Diskin
Am J Kidney Dis 52:197-8; author reply 198. 2008
Hemoglobin targets versus oxygen delivery: is it time for a new paradigm?Charles J Diskin
Blood Purif 25:280; author reply 280. 2007
Erythropoietin levels and androgens use: what is their relationship in the correction of anemia?Charles J Diskin
Arch Intern Med 167:309. 2007
The contribution of nutrition to the protective value of high plasma aldosterone concentrations in hemodialysis patientsCharles J Diskin
Hypertens Res 30:751-2; author reply 752-4. 2007
Multiple mechanisms for abnormal selenium levels and vascular disease in renal failureCharles J Diskin
Am J Kidney Dis 47:924; author reply 924-5. 2006
Notes on angiotensin inhibition and vascular access survival: time for randomized controlled trialsCharles J Diskin
Nephrol Dial Transplant 21:823; author reply 824. 2006
R wave increases after hemodialysis revisitedCharles J Diskin
Ann Noninvasive Electrocardiol 11:198-9. 2006
A change of reason: medicine and the scientific revolutionCharles J Diskin
Arch Intern Med 166:369-70; author reply 370. 2006
Looking backward: a review of the treatment of systemic lupus erythematosus in end-stage renal disease after a quarter of centuryCharles J Diskin
Nephrol Dial Transplant 21:1739. 2006
Vascular access cannulation and the end of religion: is it time or our own human variables that determine success?Charles J Diskin
Nephrol Dial Transplant 20:2010-1; author reply 2011. 2005
Pharmacologic intervention to prevent hemodialysis vascular access thrombosis: the next generation of treatment?Charles J Diskin
Kidney Int 67:2505. 2005
The clinical significance of aldosterone in ESRD: Part IICharles J Diskin
Nephrol Dial Transplant 19:1331-2; author reply 1332. 2004
Creatinine and GFR: an imperfect marriage of convenienceCharles J Diskin
Nephrol Dial Transplant 21:3338-9. 2006
Electrocardiographic R wave increases after hemodialysis: round IIICharles J Diskin
Saudi J Kidney Dis Transpl 19:648-50; author reply 650. 2008
Peritoneal dialysis in patients with liver cirrhosis and/or ascitesCharles J Diskin
Wien Klin Wochenschr 118:435; author reply 435-6. 2006
Is it time to reexamine KDOQI aluminum guidelines?Charles J Diskin
Am J Kidney Dis 48:876-7. 2006
Heparin, biofilm, and catheter-related sepsisCharles J Diskin
Diagn Microbiol Infect Dis 61:80; author reply 80-81. 2008
Is the timing of thallium injection in relation to hemodialysis treatments important?Charles J Diskin
Ther Apher Dial 11:241; author reply 242. 2007
An understanding of trace metal physiology as an aid to interpretation of clearance studies by artificial organsCharles J Diskin
Nephrol Dial Transplant 23:1462; author reply 1462-3. 2008
Hitting the target but missing the goal? Hemoglobin targets versus oxygen deliveryCharles J Diskin
Am J Kidney Dis 50:344; author reply 344. 2007
Analgesic use in hemodialysis patients: Osler at the bedside and computer-generated dataCharles J Diskin
Kidney Int 67:378-9; author reply 379. 2005
