Research Topics
| John J SimSummaryAffiliation: Kaiser Permanente Country: USA Publications
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Detail Information
Publications
Plasma renin activity (PRA) levels and antihypertensive drug use in a large healthcare systemJohn J Sim
Division of Nephrology and Hypertension, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, USA
Am J Hypertens 25:379-88. 2012..To evaluate the heterogeneity of hypertension and the medication burden associated with it, we investigated medication usage in relation to PRA among hypertensive patients within a large ethnically diverse organization...
Indinavir-induced nephrolithiasis three and one-half years after cessation of indinavir therapyJulie Huynh
Division of Nephrology and Hypertension, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA
Int Urol Nephrol 43:571-3. 2011..5 years after discontinuing indinavir. We use this case to illustrate the pathophysiology of indinavir stones and hypothesize how they can occur years after discontinuation by discussing the pharmacokinetics of the drug...
Association of plasma renin activity and aldosterone-renin ratio with prevalence of chronic kidney disease: the Kaiser Permanente Southern California cohortJohn J Sim
Division of Nephrology and Hypertension, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California 90027, USA
J Hypertens 29:2226-35. 2011....
Positive relationship of sleep apnea to hyperaldosteronism in an ethnically diverse populationJohn J Sim
Division of Nephrology and Hypertension, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA
J Hypertens 29:1553-9. 2011..Approximately, 50-60% of patients with sleep apnea have hypertension. To explore a mechanism of this relationship, we compared its prevalence in a hypertensive population with and without hyperaldosteronism...
Review article: Managing sleep apnoea in kidney diseasesJohn J Sim
Division of Nephrology and Hypertension, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA, USA
Nephrology (Carlton) 15:146-52. 2010..SA may vary in form and aetiology depending on type or stage of CKD. Based on these associations, we discuss our rationale for recommendations on screening and management of SA specific to the CKD population...
Vitamin D deficiency and anemia: a cross-sectional studyJohn J Sim
Division of Nephrology and Hypertension, Kaiser Permanente Los Angeles Medical Center, 4700 Sunset Blvd, 2nd Floor Nephrology, Los Angeles, CA 90027, USA
Ann Hematol 89:447-52. 2010..Future randomized studies are warranted to examine whether vitamin D directly affects erythropoiesis...
Sleep apnea in early and advanced chronic kidney disease: Kaiser Permanente Southern California cohortJohn J Sim
Division of Nephrology and Hypertension, Kaiser Permanente Los Angeles Medical Center, 4700 Sunset Blvd, Los Angeles, CA 90027, USA
Chest 135:710-6. 2009..This study sought to determine whether an association exists between SA and early stages of chronic kidney disease (CKD) where SA may represent an important comorbidity and potential risk factor in kidney disease...
Vitamin D supplementation and recombinant human erythropoietin utilization in vitamin D-deficient hemodialysis patientsVictoria A Kumar
Southern California Permanente Medical Group, Los Angeles Medical Center, Los Angeles, California, USA
J Nephrol 24:98-105. 2011..We sought to examine the impact of ergocalciferol (ERGO) on recombinant human erythropoietin (EPO) use in a cohort of 25-OH vitamin D (25-D)-deficient hemodialysis (HD) patients...
Sleep apnea and hypertension: prevalence in chronic kidney diseaseJohn J Sim
Division of Nephrology and Hypertension, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA 90027, USA
J Clin Hypertens (Greenwich) 9:837-41. 2007..33-1.39) more prevalent in patients with SA and CKD compared with patients with SA without CKD. The high prevalence of HTN in patients with SA and CKD suggests the need for evaluation of SA in patients with concurrent HTN and CKD...
25-hydroxyvitamin D levels and hypertension ratesSimran K Bhandari
Division of Nephrology and Hypertension, Kaiser Permanente Los Angeles Medical Center, 4700 Sunset Boulevard, Los Angeles, CA 90027, USA
J Clin Hypertens (Greenwich) 13:170-7. 2011..This retrospective analysis raises the question of whether supplementing to optimal vitamin D levels can prevent or improve hypertension...
Comparison of outcomes of peritoneal dialysis catheters placed by the fluoroscopically guided percutaneous method versus directly visualized surgical methodMelissa A Rosenthal
Department of Medicine, Division of Nephrology and Hypertension, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California 90027, USA
J Vasc Interv Radiol 19:1202-7. 2008..To compare complications in catheters placed by the fluoroscopically guided percutaneous method versus directly visualized surgery...
Prevalence of nondiabetic renal disease in diabetic patientsTam T Pham
Kaiser Permanente, Los Angeles Medical Center, Los Angeles, Calif 90027, USA
Am J Nephrol 27:322-8. 2007..Our aim was to evaluate the prevalence of nondiabetic renal disease (NDRD) in patients with type 2 diabetes mellitus to determine common clinical indicators suggestive of NDRD...
Dietary omega-3 fatty acid, ratio of omega-6 to omega-3 intake, inflammation, and survival in long-term hemodialysis patientsNazanin Noori
Harold Simmons Center for Chronic Disease Research and Epidemiology, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Torrance, CA, USA
Am J Kidney Dis 58:248-56. 2011..We hypothesized that the anti-inflammatory benefits of higher dietary intake of omega-3 compared with omega-6 polyunsaturated fatty acids may modulate the inflammatory processes and decrease death risk...
