Research Topics
| Carla M CanusoSummaryAffiliation: Johnson and Johnson Pharmaceutical Research and Development Country: USA Publications
| Collaborators |
Detail Information
Publications
Predicting hospital admission and discharge with symptom or function scores in patients with schizophrenia: pooled analysis of a clinical trial extensionChris M Kozma
University of South Carolina, Columbia, SC, USA
Ann Gen Psychiatry 9:24. 2010..The purpose of this analysis was to evaluate relationships between hospital admission or discharge and scores for symptom or functioning in patients with schizophrenia...
Paliperidone extended-release for schizophrenia: effects on symptoms and functioning in acutely ill patients with negative symptomsC M Canuso
Ortho McNeil Janssen Scientific Affairs, LLC, 1125 Trenton Harbourton Road, Titusville, NJ 08560 0200, USA
Schizophr Res 113:56-64. 2009..Most patients with schizophrenia exhibit negative symptoms, even during acute episodes. These difficult-to-treat symptoms are often associated with poor functioning and outcomes...
Paliperidone extended-release: a review of efficacy and tolerability in schizophrenia, schizoaffective disorder and bipolar maniaCarla M Canuso
Johnson and Johnson Pharmaceutical Research and Development, LLC, Titusville, NJ 08560, USA
Expert Opin Pharmacother 11:2557-67. 2010..Additional data on its efficacy and safety, including that for additional indications, is emerging...
Paliperidone extended-release in schizoaffective disorder: a randomized, controlled study comparing a flexible dose with placebo in patients treated with and without antidepressants and/or mood stabilizersCarla M Canuso
Johnson and Johnson Pharmaceutical Research and Development, LLC, Titusville, NJ, USA
J Clin Psychopharmacol 30:487-95. 2010..Paliperidone ER improved psychotic and affective symptoms both as monotherapy and as an adjunct to MS/AD. No new safety findings were observed in this population...
A randomized, double-blind, placebo-controlled study of 2 dose ranges of paliperidone extended-release in the treatment of subjects with schizoaffective disorderCarla M Canuso
Johnson and Johnson Pharmaceutical Research and Development, LLC, 1125 Trenton Harbourton Rd E12604, Titusville, NJ 08560, USA
J Clin Psychiatry 71:587-98. 2010..This study was designed to assess efficacy and safety of paliperidone extended-release (ER) in patients with schizoaffective disorder...
Medication satisfaction in schizophrenia: a blinded-initiation study of paliperidone extended release in patients suboptimally responsive to risperidoneCarla M Canuso
Ortho McNeil Janssen Scientific Affairs, LLC, 1125 Trenton Harbourton Road A32404, Titusville, NJ 08560, USA
Int Clin Psychopharmacol 25:155-64. 2010..1%), constipation (7.6%), headache (7.6%) and somnolence (6.6%). Participants with schizophrenia who were suboptimally responsive to risperidone reported improved medication satisfaction after initiation of paliperidone ER...
Efficacy and safety of paliperidone extended-release in schizophrenia patients with prominent affective symptomsCarla M Canuso
Ortho McNeil Janssen Scientific Affairs, LLC, Titusville, NJ 08560 0200, USA
J Affect Disord 120:193-9. 2010..This post-hoc analysis evaluated the effects of paliperidone extended-release (ER) in patients with schizophrenia and prominent affective symptoms...
Paliperidone extended-release tablets in patients with recently diagnosed schizophreniaCarla M Canuso
Ortho McNeil Janssen Scientific Affairs, LLC, Titusville New Jersey, USA
Early Interv Psychiatry 4:64-78. 2010..Effective early and persistent antipsychotic treatment in recently diagnosed schizophrenia may positively impact long-term outcomes. Paliperidone extended-release (ER) was assessed in this population...
Paliperidone ER and oral risperidone in patients with schizophrenia: a comparative database analysisIbrahim Turkoz
Johnson and Johnson Pharmaceutical Research and Development, LLC, Titusville, New Jersey, USA
BMC Psychiatry 11:21. 2011..To compare the efficacy and tolerability of paliperidone extended-release (ER) with risperidone immediate-release using propensity score methodology...
Randomized, double-blind, placebo-controlled study of paliperidone extended-release and quetiapine in inpatients with recently exacerbated schizophreniaCarla M Canuso
Ortho McNeil Janssen Scientific Affairs, Titusville, NJ, USA
Am J Psychiatry 166:691-701. 2009..The authors compared paliperidone extended-release and quetiapine in patients with recently exacerbated schizophrenia requiring hospitalization...
Psychotic symptoms in patients with bipolar maniaCarla M Canuso
Ortho McNeil Janssen Scientific Affairs, L L C, Titusville, New Jersey 08560, United States
J Affect Disord 111:164-9. 2008..Psychosis has been identified in as many as 68% of patients with bipolar mania. This analysis identified psychotic symptoms in these patients...
Paliperidone extended-release tablets in schizophrenia patients previously treated with risperidoneCarla M Canuso
Ortho McNeil Janssen Scientific Affairs LLC, Titusville, NJ, USA
Int Clin Psychopharmacol 23:209-15. 2008..4% with placebo. In patients who had received risperidone previously but remained sufficiently symptomatic for enrollment, paliperidone ER was significantly more effective than placebo in reducing symptoms and producing functional gains...
Adjunctive risperidone in the treatment of generalized anxiety disorder: a double-blind, prospective, placebo-controlled, randomized trialGahan J Pandina
Johnson and Johnson Pharmaceutical Research and Development, Titusville, NJ, USA
Psychopharmacol Bull 40:41-57. 2007....
Risperidone for treatment-refractory major depressive disorder: a randomized trialRamy A Mahmoud
Ortho McNeil Janssen Scientific Affairs, Titusville, New Jersey, USA
Ann Intern Med 147:593-602. 2007..Major depressive disorder has high prevalence, morbidity, and mortality. Inadequate results with antidepressants have prompts addition of a nonstandard treatment (augmentation therapy)...
Direct and indirect effects of paliperidone extended-release tablets on negative symptoms of schizophreniaIbrahim Turkoz
Ortho McNeil Janssen Scientific, Affairs, LLC, Titusville, NJ, USA
Neuropsychiatr Dis Treat 4:949-58. 2008..1% inverse effect. Path analysis indicated that paliperidone ER has a direct effect on negative symptoms. Negative symptom improvement also was indirectly mediated via changes in positive and depressive symptoms...
