Research Topics
| Jonathan E SevranskySummaryAffiliation: Johns Hopkins University Country: USA Publications
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Detail Information
Publications
Critical care trial design and interpretation: a primerJonathan E Sevransky
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA
Crit Care Med 38:1882-9. 2010..Knowledge of basic principles of clinical trial design and interpretation will assist the clinician in better applying the results of these studies into clinical practice...
Mortality in sepsis versus non-sepsis induced acute lung injuryJonathan E Sevransky
Division of Pulmonary and Critical Care, Johns Hopkins University, 5501 Hopkins Bayview Circle Baltimore, MD 21224 USA
Crit Care 13:R150. 2009..Sepsis-induced acute lung injury (ALI) has been reported to have a higher case fatality rate than other causes of ALI. However, differences in the severity of illness in septic vs. non-septic ALI patients might explain this finding...
Pulmonary vs nonpulmonary sepsis and mortality in acute lung injuryJonathan E Sevransky
Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
Chest 134:534-8. 2008..Acute lung injury (ALI) is a frequent complication of sepsis. It is unclear if a pulmonary vs nonpulmonary source of sepsis affects mortality in patients with sepsis-induced ALI...
Hemodynamic goals in randomized clinical trials in patients with sepsis: a systematic review of the literatureJonathan E Sevransky
Department of Pulmonary Critical Care Medicine, Johns Hopkins University, 5501 Hopkins Bayview Circle, Baltimore, MD 21224, USA
Crit Care 11:R67. 2007..Patients with sepsis suffer high morbidity and mortality. We sought to conduct a systematic review of the literature to evaluate the association between hemodynamic goals of therapy and patient outcomes...
Human immunodeficiency virus infection and hospital mortality in acute lung injury patientsPedro A Mendez-Tellez
Department of Anesthesiology and Critical Care Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD, USA
Crit Care Med 38:1530-5. 2010..To evaluate the impact of human immunodeficiency virus infection on hospital mortality in patients with acute lung injury and to evaluate predictors of mortality among acute lung injury patients with human immunodeficiency virus...
Long-term mortality and quality of life in sepsis: a systematic reviewBradford D Winters
Departments of Anesthesiology and Critical Care Medicine and Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Crit Care Med 38:1276-83. 2010..Whether patients with sepsis have similar long-term mortality and quality-of-life effects is unclear...
Mechanical ventilation in sepsis-induced acute lung injury/acute respiratory distress syndrome: an evidence-based reviewJonathan E Sevransky
Division of Pulmonary and Critical Care, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Crit Care Med 32:S548-53. 2004..Weaning protocols should be in place that include spontaneous breathing trials and criteria for initiating such trials. The role of high-frequency oscillatory ventilation and airway pressure release ventilation in ARDS is uncertain...
Granulocyte colony-stimulating factor has differing effects comparing intravascular versus extravascular models of sepsisJonathan E Sevransky
Division of Pulmonary and Critical Care Medicine, Johns Hopkins Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Trauma 57:618-25. 2004..Extrapolated clinically, a proinflammatory agent like G-CSF may be most beneficial with sepsis related primarily to a compartmentalized extravascular site of infection...
A 39-year-old man with hip pain and respiratory failureKelly E Dooley
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224-6801, USA
Chest 121:1345-9. 2002
Patient and intensive care unit organizational factors associated with low tidal volume ventilation in acute lung injuryNsikak J Umoh
Department of Surgery, Geisinger Medical Center, Danville, PA, USA
Crit Care Med 36:1463-8. 2008..Within the intensive care unit (ICU) setting, low tidal volume ventilation (LTVV) in patients with acute lung injury (ALI) significantly decreases mortality. However, LTVV has not achieved widespread adoption...
