Research Topics
| Milo A PuhanSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
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Detail Information
Publications
Expansion of the prognostic assessment of patients with chronic obstructive pulmonary disease: the updated BODE index and the ADO indexMilo A Puhan
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Lancet 374:704-11. 2009..We assessed the calibration of the BODE index, updated it to improve its calibration, and developed and validated a simplified index for use in primary-care settings...
Discussing study limitations in reports of biomedical studies- the need for more transparencyMilo A Puhan
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Mail room E6153, Baltimore, MD 21205, USA
Health Qual Life Outcomes 10:23. 2012..Instead of perceiving acknowledgment of limitations negatively, authors, reviewers and editors should recognize the potential of a frank and unbiased discussion of study limitations that should not jeopardize acceptance of manuscripts...
Self-efficacy instruments for patients with chronic diseases suffer from methodological limitations--a systematic reviewAnja Frei
Department of General Practice and Health Services Research, University Hospital of Zurich, Switzerland
Health Qual Life Outcomes 7:86. 2009..Our aim was to systematically identify all existing self-efficacy scales for five major chronic diseases and to assess their development and validation process...
ICE COLD ERIC--International collaborative effort on chronic obstructive lung disease: exacerbation risk index cohorts--study protocol for an international COPD cohort studyLara Siebeling
Department of General Practice, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
BMC Pulm Med 9:15. 2009..The objective of this study is to develop and validate a practical COPD disease risk index that predicts the clinical course of COPD in primary care patients with GOLD stages 2-4...
Interviewer versus self-administered health-related quality of life questionnaires - does it matter?Milo A Puhan
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Health Qual Life Outcomes 9:30. 2011....
Excess mortality in patients with AIDS in the era of highly active antiretroviral therapy: temporal changes and risk factorsMilo A Puhan
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Clin Infect Dis 51:947-56. 2010..We assessed temporal changes in excess mortality and elucidated risk factors for excess mortality in patients with AIDS diagnosed in the era of highly active antiretroviral therapy (HAART)...
The minimal important difference of exercise tests in severe COPDM A Puhan
Dept of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Eur Respir J 37:784-90. 2011..0-2.4 W), 3.2 W (95% CI 3.0-3.4 W), 3.2 W (95% CI 3.0-3.4 W) and 3.3 W (95% CI 3.0-3.5 W), while distribution-based estimates were 5.3 and 5.5 W. We suggest a MID of 26 ± 2 m for 6MWD and 4 ± 1 W for MCEC for patients with severe COPD...
Inhaled drugs to reduce exacerbations in patients with chronic obstructive pulmonary disease: a network meta-analysisMilo A Puhan
Horten Centre for patient oriented research and knowledge transfer, University of Zurich, Switzerland
BMC Med 7:2. 2009..Therefore we assessed, using a network meta-analytic technique, the relative effectiveness of the common inhaled drug regimes used to reduce exacerbations in patients with COPD...
The standard gamble showed better construct validity than the time trade-offMilo A Puhan
Horten Centre, University of Zurich, Switzerland
J Clin Epidemiol 60:1029-33. 2007..There is little evidence for the relative cross-sectional validity of the standard gamble (SG) and time trade-off (TTO). We compared these preference-based instruments in patients with Irritable Bowel Syndrome (IBS)...
Relative responsiveness of the Chronic Respiratory Questionnaire, St. Georges Respiratory Questionnaire and four other health-related quality of life instruments for patients with chronic lung diseaseMilo A Puhan
Horten Centre, University of Zurich, Switzerland
Respir Med 101:308-16. 2007..The objective of this study was to compare the responsiveness of the Chronic Respiratory Questionnaire (CRQ), the St. Georges Respiratory Questionnaire (SGRQ) and four other HRQL instruments...
Interval versus continuous high-intensity exercise in chronic obstructive pulmonary disease: a randomized trialMilo A Puhan
University of Zurich, Zurich, Switzerland
Ann Intern Med 145:816-25. 2006....
Combining scores from different patient reported outcome measures in meta-analyses: when is it justified?Milo A Puhan
Horten Centre, University of Zurich, Switzerland
Health Qual Life Outcomes 4:94. 2006....
Respiratory rehabilitation after acute exacerbation of COPD may reduce risk for readmission and mortality -- a systematic reviewMilo A Puhan
Horten Centre, University of Zurich, Switzerland
Respir Res 6:54. 2005..To study whether respiratory rehabilitation after acute exacerbation improves prognosis and health status compared to usual care, we quantified its effects using meta-analyses...
Value of supplemental interventions to enhance the effectiveness of physical exercise during respiratory rehabilitation in COPD patients. A systematic reviewMilo A Puhan
University of Zurich, Horten Centre, Switzerland
Respir Res 5:25. 2004..The aim of this research was to assess randomised controlled trials (RCTs) testing the additional benefit of supplemental interventions during respiratory rehabilitation in COPD patients...
A randomized trial of ways to describe test accuracy: the effect on physicians' post-test probability estimatesMilo A Puhan
University of Zurich, Zurich, Switzerland
Ann Intern Med 143:184-9. 2005..Some people believe that likelihood ratios provide diagnostic information that is more useful than sensitivity and specificity estimates...
Self-administration and standardisation of the chronic respiratory questionnaire: a randomised trial in three German-speaking countriesMilo A Puhan
Horten Centre, University of Zurich, Postfach Nord, CH 8091 Zurich, Switzerland
Respir Med 98:342-50. 2004..Taken these results into consideration, researchers in COPD, in particular those in German-language countries can utilise any one of four CRQ formats that have proved both valid and responsive...
More medical journals should inform their contributors about three key principles of graph constructionMilo A Puhan
Horten Centre, University of Zurich, 8091 Zurich, Switzerland
J Clin Epidemiol 59:1017-22. 2006..To identify key principles of graph construction and to review guidance on graph construction provided by medical journals...
Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary diseaseMilo A Puhan
Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 Wolfe Street, Mail room W5010, Baltimore, MD, USA, 21205
Cochrane Database Syst Rev 10:CD005305. 2011..However, in unstable COPD patients who have recently suffered an exacerbation, the effects of pulmonary rehabilitation are less established...
Where is the supporting evidence for treating mild to moderate chronic obstructive pulmonary disease exacerbations with antibiotics? A systematic reviewMilo A Puhan
Horten Centre for patient oriented research and knowledge transfer, University of Zurich, Switzerland
BMC Med 6:28. 2008..Our aim was to study the evolvement of evidence from placebo-controlled and head-to-head trials on the effects of antibiotics for the treatment of mild to moderate exacerbations of chronic obstructive pulmonary disease...
The standard gamble demonstrated lower reliability than the feeling thermometerMilo A Puhan
Horten Center, University of Zurich, Zurich, Switzerland
J Clin Epidemiol 58:458-65. 2005..Investigators should use appropriate reliability statistics when addressing related issues...
Network meta-analysis-highly attractive but more methodological research is neededTianjing Li
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21212, USA
BMC Med 9:79. 2011..Since this commentary reflects the discussion at that meeting, it is not intended to provide an overview of the field...
Recruitment barriers in a randomized controlled trial from the physicians' perspective: a postal surveyAnne Spaar
Horten Centre for patient oriented research and knowledge transfer, University of Zurich, Switzerland
BMC Med Res Methodol 9:14. 2009..Therefore, our aim was to conduct a postal survey among recruiting physicians of a multi-center trial to weigh barriers according to their impact on recruitment...
High prevalence of potential biases threatens the interpretation of trials in patients with chronic diseaseDaniela Vollenweider
Division of General Internal Medicine, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
BMC Med 9:73. 2011..Our aim was to assess such aspects of trial design and analysis for four prevalent chronic diseases...
Didgeridoo playing as alternative treatment for obstructive sleep apnoea syndrome: randomised controlled trialMilo A Puhan
Horten Centre, University of Zurich, 8091 Zurich, Switzerland
BMJ 332:266-70. 2006..CONCLUSION: Regular didgeridoo playing is an effective treatment alternative well accepted by patients with moderate obstructive sleep apnoea syndrome. Trial registration ISRCTN: 31571714...
Do citizens have minimum medical knowledge? A surveyLucas M Bachmann
Horten Centre for Patient Oriented Research, University of Zurich, Postfach Nord, Zurich, Switzerland
BMC Med 5:14. 2007..We tested to what degree Swiss adult citizens satisfy this criterion for MMK and whether people with medical experience have acquired better knowledge than those without...
The impact of complications on costs of major surgical procedures: a cost analysis of 1200 patientsRené Vonlanthen
Department of Surgery Horten Center for Patient Oriented Research, University Hospital Zurich, Zurich, Switzerland Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD
Ann Surg 254:907-13. 2011..To assess the impact of postoperative complications on full in-hospital costs per case...
