James J Pekar

Summary

Affiliation: Johns Hopkins University
Country: USA

Publications

  1. ncbi A brief introduction to functional MRI
    James J Pekar
    Johns Hopkins University School of Medicine, USA
    IEEE Eng Med Biol Mag 25:24-6. 2006
  2. ncbi Different activation dynamics in multiple neural systems during simulated driving
    Vince D Calhoun
    Division of Psychiatric Neuro Imaging, Department of Psychiatry, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Hum Brain Mapp 16:158-67. 2002
  3. ncbi On the relationship between seed-based and ICA-based measures of functional connectivity
    Suresh E Joel
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    Magn Reson Med 66:644-57. 2011
  4. ncbi Physiological origin for the BOLD poststimulus undershoot in human brain: vascular compliance versus oxygen metabolism
    Jun Hua
    Russell H Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Cereb Blood Flow Metab 31:1599-611. 2011
  5. ncbi Transient neural activity in human parietal cortex during spatial attention shifts
    Steven Yantis
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
    Nat Neurosci 5:995-1002. 2002
  6. ncbi Functional magnetic resonance imaging based on changes in vascular space occupancy
    Hanzhang Lu
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 50:263-74. 2003
  7. ncbi Effect of inflow of fresh blood on vascular-space-occupancy (VASO) contrast
    Manus J Donahue
    Russell H Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 61:473-80. 2009
  8. ncbi Tract probability maps in stereotaxic spaces: analyses of white matter anatomy and tract-specific quantification
    Kegang Hua
    Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 39:336-47. 2008
  9. ncbi Differential brain activation in anorexia nervosa to Fat and Thin words during a Stroop task
    Graham W Redgrave
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Neuroreport 19:1181-5. 2008
  10. ncbi Functional brain changes in presymptomatic Huntington's disease
    Sarah A J Reading
    Department of Psychiatry, Johns Hopkins University, Baltimore, MD 21287, USA
    Ann Neurol 55:879-83. 2004

Collaborators

Detail Information

Publications19

  1. ncbi A brief introduction to functional MRI
    James J Pekar
    Johns Hopkins University School of Medicine, USA
    IEEE Eng Med Biol Mag 25:24-6. 2006
  2. ncbi Different activation dynamics in multiple neural systems during simulated driving
    Vince D Calhoun
    Division of Psychiatric Neuro Imaging, Department of Psychiatry, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Hum Brain Mapp 16:158-67. 2002
    ..Increases in cerebellar and occipital areas, presumably related to complex visuomotor integration, are activated during driving but not associated with driving speed...
  3. ncbi On the relationship between seed-based and ICA-based measures of functional connectivity
    Suresh E Joel
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    Magn Reson Med 66:644-57. 2011
    ..We present a simple simulation and an experiment on visuomotor activity that highlight this relationship between the two methods...
  4. ncbi Physiological origin for the BOLD poststimulus undershoot in human brain: vascular compliance versus oxygen metabolism
    Jun Hua
    Russell H Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Cereb Blood Flow Metab 31:1599-611. 2011
    ..Using a biophysical model, their relative contributions were estimated to be 19.7±15.9% and 78.7±18.6%, respectively...
  5. ncbi Transient neural activity in human parietal cortex during spatial attention shifts
    Steven Yantis
    Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
    Nat Neurosci 5:995-1002. 2002
    ..This result suggests that activation of the parietal cortex is associated with a discrete signal to shift spatial attention, and is not the source of a signal to continuously maintain the current attentive state...
  6. ncbi Functional magnetic resonance imaging based on changes in vascular space occupancy
    Hanzhang Lu
    Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 50:263-74. 2003
    ..Arguments supporting a better gray matter localization for the VASO-fMRI approach compared to BOLD are provided...
  7. ncbi Effect of inflow of fresh blood on vascular-space-occupancy (VASO) contrast
    Manus J Donahue
    Russell H Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Magn Reson Med 61:473-80. 2009
    ..4% +/- 0.2%) than short-TR data (DeltaS/S = -2.2% +/- 0.2%), implying that cerebral blood flow or transit-state effects may influence VASO contrast at short TR...
  8. ncbi Tract probability maps in stereotaxic spaces: analyses of white matter anatomy and tract-specific quantification
    Kegang Hua
    Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuroimage 39:336-47. 2008
    ..Excellent correlation was found between the automated and the individual tractography-based results. This tool allows efficient initial screening of the status of multiple white matter tracts...
  9. ncbi Differential brain activation in anorexia nervosa to Fat and Thin words during a Stroop task
    Graham W Redgrave
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Neuroreport 19:1181-5. 2008
    ..Mechanisms underlying attentional bias in anorexia nervosa likely differ under conditions of positive and negative valence. This paradigm is a promising tool to examine neural mediation of emotional response in anorexia nervosa...
  10. ncbi Functional brain changes in presymptomatic Huntington's disease
    Sarah A J Reading
    Department of Psychiatry, Johns Hopkins University, Baltimore, MD 21287, USA
    Ann Neurol 55:879-83. 2004
    ..In the setting of normal cognitive performance, presymptomatic HD subjects had significantly and specifically less activation in the left anterior cingulate cortex (BA 24, 32) compared with matched controls...
  11. ncbi Functional brain correlates of response time variability in children
    Daniel J Simmonds
    Kennedy Krieger Institute, Baltimore, MD 21205, USA
    Neuropsychologia 45:2147-57. 2007
    ....
  12. ncbi Theoretical and experimental investigation of the VASO contrast mechanism
    Manus J Donahue
    Russell H. Morgan Department of Radiology and Radiological Sciences, Division of MR Research, Johns Hopkins University, Baltimore, Maryland 21205, USA
    Magn Reson Med 56:1261-73. 2006
    ..Thus, many competing effects contribute to VASO contrast and care should be taken during interpretation...
  13. ncbi Meta-analysis of Go/No-go tasks demonstrating that fMRI activation associated with response inhibition is task-dependent
    Daniel J Simmonds
    Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205, USA
    Neuropsychologia 46:224-32. 2008
    ....
  14. ncbi fMRI evidence that the neural basis of response inhibition is task-dependent
    Stewart H Mostofsky
    Developmental Cognitive Neurology, Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205, USA
    Brain Res Cogn Brain Res 17:419-30. 2003
    ....
  15. ncbi Functional magnetic resonance imaging evidence for abnormalities in response selection in attention deficit hyperactivity disorder: differences in activation associated with response inhibition but not habitual motor response
    Stacy J Suskauer
    Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205, USA
    J Cogn Neurosci 20:478-93. 2008
    ....
  16. ncbi A method for multitask fMRI data fusion applied to schizophrenia
    Vince D Calhoun
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
    Hum Brain Mapp 27:598-610. 2006
    ..It thus provides a way to integrate and probe brain networks using a variety of tasks and may increase our understanding of coordinated brain networks and the impact of pathology upon them...
  17. ncbi Atypical motor and sensory cortex activation in attention-deficit/hyperactivity disorder: a functional magnetic resonance imaging study of simple sequential finger tapping
    Stewart H Mostofsky
    Kennedy Krieger Institute, Baltimore, MD 21205, USA
    Biol Psychiatry 59:48-56. 2006
    ..Functional magnetic resonance imaging (fMRI) was used to determine whether differences in brain activation during sequential finger tapping are present in children with ADHD compared with typically developing control subjects...
  18. ncbi Alcohol intoxication effects on simulated driving: exploring alcohol-dose effects on brain activation using functional MRI
    Vince D Calhoun
    Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT, USA
    Neuropsychopharmacology 29:2097-17. 2004
    ..The fMRI data also suggest that the deficits observed in alcohol intoxication may be modulated primarily through OF/anterior cingulate, motor and cerebellar regions as opposed to attentional areas in frontoparietal cortex...
  19. ncbi An account of the discrepancy between MRI and PET cerebral blood flow measures. A high-field MRI investigation
    Manus J Donahue
    The Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University, Baltimore, MD, USA
    NMR Biomed 19:1043-54. 2006
    ..The recent availability of MRI field strengths of 3.0 T and higher will facilitate the use of MRI-based CBF measurements in the clinic...