Research Topics | James J PekarSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
A brief introduction to functional MRIJames J Pekar
Johns Hopkins University School of Medicine, USA
IEEE Eng Med Biol Mag 25:24-6. 2006
Different activation dynamics in multiple neural systems during simulated drivingVince D Calhoun
Division of Psychiatric Neuro Imaging, Department of Psychiatry, Johns Hopkins University, Baltimore, Maryland 21205, USA
Hum Brain Mapp 16:158-67. 2002..Increases in cerebellar and occipital areas, presumably related to complex visuomotor integration, are activated during driving but not associated with driving speed...
On the relationship between seed-based and ICA-based measures of functional connectivitySuresh E Joel
Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Magn Reson Med 66:644-57. 2011..We present a simple simulation and an experiment on visuomotor activity that highlight this relationship between the two methods...
Physiological origin for the BOLD poststimulus undershoot in human brain: vascular compliance versus oxygen metabolismJun Hua
Russell H Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
J Cereb Blood Flow Metab 31:1599-611. 2011..Using a biophysical model, their relative contributions were estimated to be 19.7±15.9% and 78.7±18.6%, respectively...
Transient neural activity in human parietal cortex during spatial attention shiftsSteven Yantis
Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
Nat Neurosci 5:995-1002. 2002..This result suggests that activation of the parietal cortex is associated with a discrete signal to shift spatial attention, and is not the source of a signal to continuously maintain the current attentive state...
Functional magnetic resonance imaging based on changes in vascular space occupancyHanzhang Lu
Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Magn Reson Med 50:263-74. 2003..Arguments supporting a better gray matter localization for the VASO-fMRI approach compared to BOLD are provided...
Effect of inflow of fresh blood on vascular-space-occupancy (VASO) contrastManus J Donahue
Russell H Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Magn Reson Med 61:473-80. 2009..4% +/- 0.2%) than short-TR data (DeltaS/S = -2.2% +/- 0.2%), implying that cerebral blood flow or transit-state effects may influence VASO contrast at short TR...
Tract probability maps in stereotaxic spaces: analyses of white matter anatomy and tract-specific quantificationKegang Hua
Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Neuroimage 39:336-47. 2008..Excellent correlation was found between the automated and the individual tractography-based results. This tool allows efficient initial screening of the status of multiple white matter tracts...
Differential brain activation in anorexia nervosa to Fat and Thin words during a Stroop taskGraham W Redgrave
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Neuroreport 19:1181-5. 2008..Mechanisms underlying attentional bias in anorexia nervosa likely differ under conditions of positive and negative valence. This paradigm is a promising tool to examine neural mediation of emotional response in anorexia nervosa...
Functional brain changes in presymptomatic Huntington's diseaseSarah A J Reading
Department of Psychiatry, Johns Hopkins University, Baltimore, MD 21287, USA
Ann Neurol 55:879-83. 2004..In the setting of normal cognitive performance, presymptomatic HD subjects had significantly and specifically less activation in the left anterior cingulate cortex (BA 24, 32) compared with matched controls...
Functional brain correlates of response time variability in childrenDaniel J Simmonds
Kennedy Krieger Institute, Baltimore, MD 21205, USA
Neuropsychologia 45:2147-57. 2007....
Theoretical and experimental investigation of the VASO contrast mechanismManus J Donahue
Russell H. Morgan Department of Radiology and Radiological Sciences, Division of MR Research, Johns Hopkins University, Baltimore, Maryland 21205, USA
Magn Reson Med 56:1261-73. 2006..Thus, many competing effects contribute to VASO contrast and care should be taken during interpretation...
Meta-analysis of Go/No-go tasks demonstrating that fMRI activation associated with response inhibition is task-dependentDaniel J Simmonds
Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205, USA
Neuropsychologia 46:224-32. 2008....
fMRI evidence that the neural basis of response inhibition is task-dependentStewart H Mostofsky
Developmental Cognitive Neurology, Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205, USA
Brain Res Cogn Brain Res 17:419-30. 2003....
Functional magnetic resonance imaging evidence for abnormalities in response selection in attention deficit hyperactivity disorder: differences in activation associated with response inhibition but not habitual motor responseStacy J Suskauer
Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205, USA
J Cogn Neurosci 20:478-93. 2008....
A method for multitask fMRI data fusion applied to schizophreniaVince D Calhoun
Olin Neuropsychiatry Research Center, Institute of Living, Hartford, Connecticut 06106, USA
Hum Brain Mapp 27:598-610. 2006..It thus provides a way to integrate and probe brain networks using a variety of tasks and may increase our understanding of coordinated brain networks and the impact of pathology upon them...
Atypical motor and sensory cortex activation in attention-deficit/hyperactivity disorder: a functional magnetic resonance imaging study of simple sequential finger tappingStewart H Mostofsky
Kennedy Krieger Institute, Baltimore, MD 21205, USA
Biol Psychiatry 59:48-56. 2006..Functional magnetic resonance imaging (fMRI) was used to determine whether differences in brain activation during sequential finger tapping are present in children with ADHD compared with typically developing control subjects...
Alcohol intoxication effects on simulated driving: exploring alcohol-dose effects on brain activation using functional MRIVince D Calhoun
Olin Neuropsychiatry Research Center, Institute of Living, Hartford, CT, USA
Neuropsychopharmacology 29:2097-17. 2004..The fMRI data also suggest that the deficits observed in alcohol intoxication may be modulated primarily through OF/anterior cingulate, motor and cerebellar regions as opposed to attentional areas in frontoparietal cortex...
An account of the discrepancy between MRI and PET cerebral blood flow measures. A high-field MRI investigationManus J Donahue
The Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, Johns Hopkins University, Baltimore, MD, USA
NMR Biomed 19:1043-54. 2006..The recent availability of MRI field strengths of 3.0 T and higher will facilitate the use of MRI-based CBF measurements in the clinic...
