Research Topics
| James P DunnSummaryAffiliation: Johns Hopkins University Country: USA Publications
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Publications
Mycophenolate mofetil therapy for inflammatory eye diseaseJennifer E Thorne
Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Ophthalmology 112:1472-7. 2005..To evaluate treatment outcomes with mycophenolate mofetil in patients with inflammatory eye disease...
Retinal vascular occlusion in patients infected with human immunodeficiency virusJames P Dunn
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Retina 25:759-66. 2005..To describe the clinical features of retinal vascular occlusions (macrovasculopathy) and the proportion of affected patients with human immunodeficiency virus (HIV) infection...
Review of immunosuppressive drug therapy in uveitisJames P Dunn
Department of Ophthalmology, Division of Ocular Immunology, The Wilmer Eye Institute, The Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
Curr Opin Ophthalmol 15:293-8. 2004..This review was undertaken to highlight recent clinical advances in the treatment of severe noninfectious uveitis...
Multifocal choroiditis with panuveitis and punctate inner choroidopathy: comparison of clinical characteristics at presentationSanjay R Kedhar
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Retina 27:1174-9. 2007..To compare the clinical characteristics at presentation of multifocal choroiditis with panuveitis (MFCPU) and punctate inner choroidopathy (PIC)...
Juvenile idiopathic arthritis-associated uveitis: incidence of ocular complications and visual acuity lossJennifer E Thorne
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Am J Ophthalmol 143:840-846. 2007....
Incidence of cystoid macular edema after cataract surgery in patients with and without uveitis using optical coherence tomographyMarie Lyne Belair
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Ophthalmol 148:128-35.e2. 2009..To determine the incidence of cystoid macular edema (CME) after cataract surgery among eyes with and without uveitis using optical coherence tomography (OCT) and to determine risk factors for postoperative CME among eyes with uveitis...
A method of reporting macular edema after cataract surgery using optical coherence tomographyStephen J Kim
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA 30322, USA
Retina 28:870-6. 2008..To validate a method of reporting postcataract macular edema (ME) using optical coherence tomography (OCT)...
Loss of visual field among patients with birdshot chorioretinopathyJennifer E Thorne
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Ophthalmol 145:23-28. 2008..To describe the prevalence and incidence of loss of visual field among patients with birdshot chorioretinopathy (BSCR) and to describe the effect of therapy on such field loss in these patients...
Clinical characteristics and outcomes of cytomegalovirus retinitis in persons without human immunodeficiency virus infectionIrene C Kuo
Department of Ophthalmology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
Am J Ophthalmol 138:338-46. 2004..To describe the characteristics and outcomes of patients with cytomegalovirus (CMV) retinitis in the absence of human immunodeficiency virus (HIV) infection...
Incidence of cytomegalovirus (CMV) retinitis in second eyes of patients with the acquired immune deficiency syndrome and unilateral CMV retinitisJohn H Kempen
Department of Ophthalmology, The Johns Hopkins University School of Medicine, 550 North Broadway, Suite 700, Baltimore, MD 21205, USA
Am J Ophthalmol 139:1028-34. 2005..To evaluate the risk and risk factors for developing cytomegalovirus (CMV) retinitis in previously uninvolved second eyes among patients with unilateral CMV retinitis...
Course of cytomegalovirus retinitis in the era of highly active antiretroviral therapy: five-year outcomesDouglas A Jabs
Department of Ophthalmology, The Mount Sinai School of Medicine, New York, New York, USA
Ophthalmology 117:2152-61.e1-2. 2010..To describe the 5-year outcomes of patients with cytomegalovirus (CMV) retinitis and AIDS in the era of highly active antiretroviral therapy (HAART)...
Comparison of antimetabolite drugs as corticosteroid-sparing therapy for noninfectious ocular inflammationAnat Galor
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Ophthalmology 115:1826-32. 2008..To compare the relative effectiveness and side effect profiles of antimetabolite drugs in the treatment of noninfectious ocular inflammation...
Optic neuropathy complicating multifocal choroiditis and panuveitisJennifer E Thorne
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Ophthalmol 143:721-3. 2007..To describe the clinical characteristics of patients with optic neuropathy complicating multifocal choroiditis and panuveitis (MFCPU)...
Vogt-Koyanagi-Harada disease: clinical outcomesIrina Bykhovskaya
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Ophthalmol 140:674-8. 2005..08; P = .04, respectively). CONCLUSION: VKH disease may result in substantial visual impairment. The use of oral corticosteroid or immunosuppressive drug therapy may reduce the risk of vision loss during the follow-up period...
Evaluation of the United States public health service guidelines for discontinuation of anticytomegalovirus therapy after immune recovery in patients with cytomegalovirus retinitisJanet T Holbrook
Center for Clinical Trials, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21232, USA
Am J Ophthalmol 152:628-637.e1. 2011....
Mortality risk for patients with cytomegalovirus retinitis and acquired immune deficiency syndromeJohn H Kempen
Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
Clin Infect Dis 37:1365-73. 2003....
Periocular triamcinolone acetonide injections for cystoid macular edema complicating noninfectious uveitisHenry A Leder
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Ophthalmol 152:441-448.e2. 2011..To describe the effectiveness of periocular corticosteroid injections in the treatment of cystoid macular edema (CME) complicating noninfectious uveitis...
Risk of cataract development among children with juvenile idiopathic arthritis-related uveitis treated with topical corticosteroidsJennifer E Thorne
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Ophthalmology 117:1436-41. 2010..We sought to investigate the risk of cataract development among patients with juvenile idiopathic arthritis (JIA)-associated uveitis treated with topical corticosteroids...
Multifocal choroiditis with panuveitis incidence of ocular complications and of loss of visual acuityJennifer E Thorne
Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Ophthalmology 113:2310-6. 2006..To estimate the incidences of ocular complications and vision loss in patients with multifocal choroiditis with panuveitis (MFCPU) and to describe the association between therapy and the incidences thereof...
Ganciclovir implant in the treatment of cytomegalovirus retinitisMargaret Chang
The Wilmer Eye Institute, The Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
Expert Rev Med Devices 2:421-7. 2005..In addition, the implant provides no protection against second-eye or visceral cytomegalovirus retinitis infections. This review summarizes the clinical indications for and complications associated with the ganciclovir implant...
Incidence and management of cataract after retinal detachment repair with silicone oil in immune compromised patients with cytomegalovirus retinitisAngelo P Tanna
Department of Ophthalmology, Northwestern University Medical School, Chicago, Illinois, USA
Am J Ophthalmol 136:1009-15. 2003..To determine the incidence of and risk factors for cataract and to describe the visual outcomes of cataract surgery in eyes with cytomegalovirus-related retinal detachments repaired with silicone oil...
Complications of ganciclovir implant surgery in patients with cytomegalovirus retinitis: the Ganciclovir Cidofovir Cytomegalovirus Retinitis TrialJames P Dunn
Department of Ophthalmology, Wilmer Eye Institute, The Johns Hopkins University School of Medicine, 550 North Broadway, Baltimore, MD 21205, USA
Retina 24:41-50. 2004..Vitreous hemorrhage was the most commonly observed complication and resolved in all cases...
Long-term preservation of vision in progressive outer retinal necrosis treated with combination antiviral drugs and highly active antiretroviral therapyStephen J Kim
The Johns Hopkins Hospital, The Wilmer Eye Institute, Ophthalmology, Baltimore 21205, USA
Ocul Immunol Inflamm 15:425-7. 2007..To report the successful long-term treatment of varicella zoster virus-associated progressive outer retinal necrosis (VZV-PORN) with aggressive antiviral combination drugs along with highly active antiretroviral therapy (HAART)...
Birdshot retinochoroidopathy: ocular complications and visual impairmentJennifer E Thorne
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, MD 21250, USA
Am J Ophthalmol 140:45-51. 2005..To describe the incidence of vision loss and of ocular complications attributable to birdshot retinochoroidopathy and to describe the association between therapy and the incidence thereof...
Papillary conjunctivitis associated with Kikuchi diseaseAnat Galor
Division of Ocular Immunology, Johns Hopkins University, Baltimore, MD 21287, USA
Cornea 27:944-6. 2008..To describe a case of papillary conjunctivitis associated with Kikuchi-Fujimoto disease (KFD)...
Smoking as a risk factor for cystoid macular edema complicating intermediate uveitisJennifer E Thorne
Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
Am J Ophthalmol 145:841-6. 2008..To describe risk factors for the presence of cystoid macular edema (CME) among patients presenting with intermediate uveitis...
Risk factors for ocular complications and poor visual acuity at presentation among patients with uveitis associated with juvenile idiopathic arthritisFasika Woreta
Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Ophthalmol 143:647-55. 2007..To describe the frequencies of and risk factors for ocular complications and poor visual acuity at presentation in a cohort of patients with juvenile idiopathic arthritis (JIA)-associated uveitis...
Cancer-associated retinopathy with retinal periphlebitis in a patient with ovarian cancerStephen J Kim
Department of Ophthalmology, Vanderbilt University, Nashville, Tennessee 37232, USA
Ocul Immunol Inflamm 18:107-9. 2010..To describe a case of cancer-associated retinopathy (CAR) due to ovarian cancer presenting with retinal periphlebitis and a negative-type pattern electroretinogram (ERG)...
Transient band keratopathy associated with ocular inflammation and systemic hypercalcemiaAnat Galor
The Wilmer Eye Institute, Department of Ophthalmology, The Johns Hopkins University School of Medicine
Clin Ophthalmol 2:645-7. 2008..To report a case of visually significant band keratopathy associated with ocular inflammation and systemic hypercalcemia which markedly decreased in severity after treatment of these underlying factors...
Acute posterior multifocal placoid pigment epitheliopathy associated with a systemic necrotizing vasculitisCynthia T Hsu
Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Retina 23:64-8. 2003....
Risk of vision loss in patients with cytomegalovirus retinitis and the acquired immunodeficiency syndromeJohn H Kempen
Department of Ophthalmology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
Arch Ophthalmol 121:466-76. 2003..To characterize the effect of cytomegalovirus (CMV) retinitis and its treatment on visual acuity in patients with the acquired immunodeficiency syndrome...
Bilateral cryptococcal choroiditisHoward F Fine
The Wilmer Eye Institute, Baltimore, MD 21205, USA
Arch Ophthalmol 122:1726-7. 2004
Cytomegalovirus retinitis in 2003James P Dunn
Hopkins HIV Rep 15:8-11. 2003
Comparability of two fundus photograph reading centers in grading cytomegalovirus retinitis progressionLarry D Hubbard
Department of Ophthalmology and Visual Sciences, The University of Wisconsin Medical School, Madison Wisconsin 53711 1068, USA
Am J Ophthalmol 137:426-34. 2004..To compare grading of cytomegalovirus retinitis progression by two different fundus photograph reading centers (FPRCs)...
Discovery of triazolinone non-nucleoside inhibitors of HIV reverse transcriptaseZachary K Sweeney
Roche Palo Alto LLC, 3431 Hillview Avenue, Palo Alto, CA 94304, USA
Bioorg Med Chem Lett 18:4348-51. 2008..Pharmacokinetic studies indicated that inhibitor 7e has good bioavailability in rats. Several fragments of inhibitor 7c were prepared, and the binding of these compounds to HIV-RT was analyzed by surface plasmon resonance spectroscopy...
Sarcoidosis and scleritisJames P Dunn
Ocul Immunol Inflamm 12:85-6. 2004
Preclinical evaluation of a novel episcleral cyclosporine implant for ocular graft-versus-host diseaseHyuncheol Kim
National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892-1863, USA
Invest Ophthalmol Vis Sci 46:655-62. 2005....
