Research Topics
| F DominiciSummaryAffiliation: Johns Hopkins Bloomberg School of Public Health Country: USA Publications
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Detail Information
Publications
Testing the harvesting hypothesis by time-domain regression analysis. I: baseline analysisKaren Fung
Department of Mathematics and Statistics, University of Windsor, Windsor, Ontario, Canada
J Toxicol Environ Health A 68:1137-54. 2005..If pollution affects mortality in the frail pool more than entrants, larger effects will occur at shorter time scales...
Risk models for particulate air pollutionFrancesca Dominici
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
J Toxicol Environ Health A 66:1883-9. 2003
Model selection and health effect estimation in environmental epidemiologyFrancesca Dominici
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Epidemiology 19:558-60. 2008..This is true especially when model choice and estimation are performed on the same data. The development of appropriate statistical tools remains an open area of investigation...
Revised analyses of the National Morbidity, Mortality, and Air Pollution Study: mortality among residents of 90 citiesFrancesca Dominici
Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
J Toxicol Environ Health A 68:1071-92. 2005..The findings of the updated analysis with regard to spatial heterogeneity across the 90 cities were unchanged from the original analyses...
Hierarchical bivariate time series models: a combined analysis of the effects of particulate matter on morbidity and mortalityFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, 615 N Wolfe Street, The Johns Hopkins University, Baltimore, MD 21205 3179, USA
Biostatistics 5:341-60. 2004..We illustrate this prediction using New York as an example...
Fine particulate air pollution and hospital admission for cardiovascular and respiratory diseasesFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
JAMA 295:1127-34. 2006..5 microm in aerodynamic diameter [PM2.5]) is limited. Results from the new national monitoring network for PM2.5 make possible systematic research on health risks at national and regional scales...
Airborne particulate matter and mortality: timescale effects in four US citiesFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Epidemiol 157:1055-65. 2003..These analyses provide additional evidence that associations between particle indexes and mortality do not imply only an advance in the timing of death by a few days for frail individuals...
National maps of the effects of particulate matter on mortality: exploring geographical variationFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland 21205 3179, USA
Environ Health Perspect 111:39-44. 2003....
Smooth quantile ratio estimation with regression: estimating medical expenditures for smoking-attributable diseasesFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, The Johns Hopkins University Baltimore, MD 21205 3179, USA
Biostatistics 6:505-19. 2005..Using a simulation study, we compare frequentist properties of two-part regression SQUARE with maximum likelihood estimators for the log-transformed expenditures...
On the use of generalized additive models in time-series studies of air pollution and healthFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205 3179, USA
Am J Epidemiol 156:193-203. 2002..The authors found that pooled NMMAPS estimates were very similar under the first and third methods but were biased upward under the second method...
Does the effect of PM10 on mortality depend on PM nickel and vanadium content? A reanalysis of the NMMAPS dataFrancesca Dominici
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21215, USA
Environ Health Perspect 115:1701-3. 2007..They found that average concentrations of nickel or vanadium in PM2.5 (PM with aerodynamic diameter < 2.5 microm) positively modified the lag-1 day association between PM10 and all-cause mortality...
Invited commentary: air pollution and health-what can we learn from a hierarchical approach?Francesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, 615 North Wolfe Street, Room E4138, Baltimore, MD 21205, USA
Am J Epidemiol 155:11-5; discussion 16. 2002
Bayesian semiparametric analysis of developmental toxicology dataF Dominici
Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland 21205, USA
Biometrics 57:150-7. 2001....
Particulate air pollution and mortality in the United States: did the risks change from 1987 to 2000?Francesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Epidemiol 166:880-8. 2007..The methodology presented can be used to track the health effects of air pollution routinely on regional and national scales...
Combining contingency tables with missing dimensionsF Dominici
Department of Biostatistics, The Johns Hopkins University, Baltimore, Maryland 21205 3179, USA
Biometrics 56:546-53. 2000....
Methodological challenges and contributions in disaster epidemiologyFrancesca Dominici
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkinds University, Baltimore, MD 21205, USA
Epidemiol Rev 27:9-12. 2005
Exposure measurement error in time-series studies of air pollution: concepts and consequencesS L Zeger
Johns Hopkins University, School of Public Health, Baltimore, Maryland, USA
Environ Health Perspect 108:419-26. 2000..Finally, we summarize open questions regarding measurement error and suggest the kind of additional data necessary to address them...
Fine particulate air pollution and mortality in 20 U.S. cities, 1987-1994J M Samet
Department of Epidemiology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
N Engl J Med 343:1742-9. 2000..Although these findings have helped lead to a tightening of air-quality standards, their validity with respect to public health has been questioned...
Mortality in the Medicare population and chronic exposure to fine particulate air pollution in urban centers (2000-2005)Scott L Zeger
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Environ Health Perspect 116:1614-9. 2008..5 microm in aerodynamic diameter (PM(2.5)) because few studies have been carried out and the cohorts have not been representative...
Fine particulate matter and mortality: a comparison of the six cities and American Cancer Society cohorts with a medicare cohortSorina E Eftim
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Epidemiology 19:209-16. 2008..5) on mortality. Using Medicare data, we assessed the association of PM2.5 with mortality for the same locations included in these studies...
Time-series studies of particulate matterMichelle L Bell
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Annu Rev Public Health 25:247-80. 2004....
Protecting human health from air pollution: shifting from a single-pollutant to a multipollutant approachFrancesca Dominici
Department of Biostatistics, Harvard University School of Public Health, Boston, MA 02115, USA
Epidemiology 21:187-94. 2010..quot; Although there is general agreement that multipollutant approaches are desirable, the challenges of implementing them are vast...
Trends in air pollution and mortality: an approach to the assessment of unmeasured confoundingHolly Janes
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Epidemiology 18:416-23. 2007..5 and mortality at the local scale. If the association at the national scale is set aside, there is little evidence of an association between 12-month exposure to PM2.5 and mortality...
Treatment effects of maternal micronutrient supplementation vary by percentiles of the birth weight distribution in rural NepalJoanne Katz
Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205 2103, USA
J Nutr 136:1389-94. 2006..Future analytic approaches to estimating benefits of maternal supplementation on birth weight should examine whether there is a constant or variable treatment effect across the distribution of birth weight...
Coarse particulate matter air pollution and hospital admissions for cardiovascular and respiratory diseases among Medicare patientsRoger D Peng
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
JAMA 299:2172-9. 2008..5) have been studied extensively over the last decade. Evidence concerning the health risks of the coarse fraction of greater than 2.5 microm and 10 microm or less in aerodynamic diameter (PM10-2.5) is limited...
New problems for an old design: time series analyses of air pollution and healthJonathan M Samet
Johns Hopkins Bloomberg School of Public Health, Department of Epidemiology, Baltimore, MD 21205, USA
Epidemiology 14:11-2. 2003
State-of-the-science workshop report: issues and approaches in low-dose-response extrapolation for environmental health risk assessmentRonald H White
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Environ Health Perspect 117:283-7. 2009....
Emergency admissions for cardiovascular and respiratory diseases and the chemical composition of fine particle air pollutionRoger D Peng
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Environ Health Perspect 117:957-63. 2009..5) (particulate matter <or= 2.5 microm in aerodynamic diameter) as the indicator. Evidence regarding the toxicity of the chemical components of the PM(2.5) mixture is limited...
Determinants of hair nicotine concentrations in nonsmoking women and children: a multicountry study of secondhand smoke exposure in homesSungroul Kim
Institute for Global Tobacco Control, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Cancer Epidemiol Biomarkers Prev 18:3407-14. 2009..The association between children's exposure to secondhand tobacco smoke at home and hair nicotine concentration was stronger among younger children and children with longer exposure at home...
Reproducible epidemiologic researchRoger D Peng
Biostatistics Department, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street E3535, Baltimore, MD 21205, USA
Am J Epidemiol 163:783-9. 2006..They also propose methods for reproducible research and implement them by use of a case study in air pollution and health...
Estimating treatment efficacy over time: a logistic regression model for binary longitudinal outcomesLeena Choi
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Stat Med 24:2789-805. 2005....
Seasonal analyses of air pollution and mortality in 100 US citiesRoger D Peng
Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, 6125 North Wolfe Street, Baltimore, MD 21205, USA
Am J Epidemiol 161:585-94. 2005..These results provide useful information for understanding particle toxicity and guiding future analyses of particle constituent data...
Multisite time-series studies versus cohort studies: methods, findings, and policy implicationsSorina Eftim
Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
J Toxicol Environ Health A 68:1191-205. 2005....
A case-crossover study of fine particulate matter air pollution and onset of congestive heart failure symptom exacerbation leading to hospitalizationJ M Symons
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
Am J Epidemiol 164:421-33. 2006....
Concentrations of vehicle-related air pollutants in an urban parking garageSung R Kim
Department of Environmental Health Sciences Rm W7014, Johns Hopkins School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
Environ Res 105:291-9. 2007..5-0.6%) coefficient was observed for light-trucks relative to cars. This study has public health relevance in providing a unique assessment of air pollution levels and source contribution for the urban parking garage...
Temperature and mortality among the elderly in the United States: a comparison of epidemiologic methodsRupa Basu
Departments of Epidemiology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland
Epidemiology 16:58-66. 2005..Our objective was to compare time-series and case-crossover analyses using varying referent periods (ie, unidirectional, ambidirectional, and time-stratified)...
Ambient air pollution alters heart rate regulation in aged miceJuan P Ramos-Bonilla
Department of Environmental Health Sciences, Johns Hopkins University School of Public Health, Baltimore, Maryland 21205, USA
Inhal Toxicol 22:330-9. 2010..Heart rate alterations associated with exposure to particulate matter (PM) and gaseous pollutants have been observed in epidemiological studies and animal experiments. Nevertheless, the time-lag of these associations is still unclear...
Asthma in older patients: factors associated with hospitalizationGregory B Diette
Department of Medicine, School of Medicine, Johns Hopkins University, Room 301, 1830 E Monument St, Baltimore, MD 21205, USA
Arch Intern Med 162:1123-32. 2002..Although older adults (> or =65 years) with asthma have higher rates of hospitalization and death from asthma than younger adults, the reasons for this are not known...
Randomized controlled trial of prenatal zinc supplementation and fetal bone growthMario Merialdi
Center for Human Nutrition, Bloomberg School of Public Health, The Johns Hopkins University, 615 North Wolfe Street, Room W2041, Baltimore, MD 21205, USA
Am J Clin Nutr 79:826-30. 2004....
Application of a propensity score approach for risk adjustment in profiling multiple physician groups on asthma careI-Chan Huang
Department of Health Policy and Management, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21205-1901, USA
Health Serv Res 40:253-78. 2005..Propensity score-based risk adjustment should be considered in studies examining quality comparisons...
Is risk-adjustor selection more important than statistical approach for provider profiling? Asthma as an exampleI-Chan Huang
Department of Health Policy and Management, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland 21205-1901, USA
Med Decis Making 25:20-34. 2005..Stakeholders employing provider profiling should pay careful attention to the selection of both variables and statistical approach used in risk-adjustment...
Outcomes of kidneys from donors after cardiac death: implications for allocation and preservationJ E Locke
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Am J Transplant 7:1797-807. 2007..These findings suggest that DCD <50 kidneys function like SCD kidneys and should not be viewed as marginal or ECD, and further, limiting CIT <12 h markedly reduces DGF...
Reduction of in-hospital mortality among California hospitals meeting Leapfrog evidence-based standards for abdominal aortic aneurysm repairBenjamin S Brooke
Department of Surgery, Division of Vascular Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Vasc Surg 47:1155-6; discussion 1163-4. 2008..The purpose of this study was to determine whether meeting these benchmarks correlated with improved patient outcomes over time...
Randomized controlled trial of prenatal zinc supplementation and the development of fetal heart rateMario Merialdi
Center for Human Nutrition, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, MD 21287, USA
Am J Obstet Gynecol 190:1106-12. 2004..No differences in motor activity were observed. CONCLUSION: Prenatal supplementation of zinc-deficient mothers may be beneficial to fetal neurobehavioral development...
Donor ethnicity influences outcomes following deceased-donor kidney transplantation in black recipientsJayme E Locke
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21205, USA
J Am Soc Nephrol 19:2011-9. 2008..41; 95% confidence interval 0.2 to 0.87; P = 0.02) among black recipients. These findings suggest that kidneys obtained from black donors after cardiac death may afford the best long-term survival for black recipients...
Predicting patient-reported asthma outcomes for adults in managed careRobin A Yurk
Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA
Am J Manag Care 10:321-8. 2004..Risk models based on patient-reported data could be used to target individuals for intervention...
Prompt reduction in use of medications for comorbid conditions after bariatric surgeryJodi B Segal
Johns Hopkins University School of Medicine, 1830 E Monument St Room 8047, Baltimore, MD 21287, USA
Obes Surg 19:1646-56. 2009..We explored this by assessing the change in use of medications to treat diabetes mellitus, hypertension, and hyperlipidemia in the year following surgery...
Reduced incidence of gestational diabetes with bariatric surgeryAnne E Burke
Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Am Coll Surg 211:169-75. 2010..Our objective was to determine the association of bariatric surgery with the incidence of GDM and related complications...
Urinary biomarkers of 1,3-butadiene in environmental settings using liquid chromatography isotope dilution tandem mass spectrometryAmir Sapkota
Department of Environmental Health Sciences, Johns Hopkins University Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA
Chem Biol Interact 160:70-9. 2006....
The exposure-response curve for ozone and risk of mortality and the adequacy of current ozone regulationsMichelle L Bell
School of Forestry and Environmental Studies, Yale University, 205 Prospect Street, New Haven, CT 06511, USA
Environ Health Perspect 114:532-6. 2006..Interventions to further reduce O3 pollution would benefit public health, even in regions that meet current regulatory standards and guidelines...
On the relationship between time-series studies, dynamic population studies, and estimating loss of life due to short-term exposure to environmental risksRichard T Burnett
Biostatistics and Epidemiology Division, Safe Environments Directorate, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada
Environ Health Perspect 111:1170-4. 2003..Issues in extrapolating risk estimates based on time-series studies in one population to estimate the amount of life lost in another population are also discussed...
A meta-analysis of time-series studies of ozone and mortality with comparison to the national morbidity, mortality, and air pollution studyMichelle L Bell
Yale University, School of Forestry and Environmental Studies, New Haven, CT 06511, USA
Epidemiology 16:436-45. 2005..Although many time-series studies of ozone and mortality have identified positive associations, others have yielded null or inconclusive results, making the results of these studies difficult to interpret...
Underestimation of standard errors in multi-site time series studiesMichael J Daniels
Department of Statistics, University of Florida, Gainesville, Florida 32611, USA
Epidemiology 15:57-62. 2004..We found that variance underestimation as large as 40% had little effect on the national average...
Spatial and temporal variation in PM(2.5) chemical composition in the United States for health effects studiesMichelle L Bell
School of Forestry and Environmental Studies, Yale University, New Haven, Connecticut, USA
Environ Health Perspect 115:989-95. 2007..Although numerous studies have demonstrated links between particulate matter (PM) and adverse health effects, the chemical components of the PM mixture that cause injury are unknown...
Potential confounding of particulate matter on the short-term association between ozone and mortality in multisite time-series studiesMichelle L Bell
School of Forestry and Environmental Studies, Yale University, New Haven, Connecticut 06511, USA
Environ Health Perspect 115:1591-5. 2007..A critical question regarding the association between short-term exposure to ozone and mortality is the extent to which this relationship is confounded by ambient exposure to particles...
Effect modification by community characteristics on the short-term effects of ozone exposure and mortality in 98 US communitiesMichelle L Bell
School of Forestry and Environmental Studies, Yale University, New Haven, CT 06511
Am J Epidemiol 167:986-97. 2008..These differences may relate to underlying health status, differences in exposure, or other factors. Results show that some segments of the population may face higher health burdens of ozone pollution...
Ozone and short-term mortality in 95 US urban communities, 1987-2000Michelle L Bell
School of Forestry and Environmental Studies, Yale University, New Haven, Conn 06511, USA
JAMA 292:2372-8. 2004..Although numerous time-series studies have estimated associations between day-to-day variation in ozone levels and mortality counts, results have been inconclusive...
Bayesian model averaging in time-series studies of air pollution and mortalityDuncan C Thomas
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089 9011, USA
J Toxicol Environ Health A 70:311-5. 2007..This paper examines recent attempts to use BMA in air pollution studies to illustrate the potential benefits and limitations of the method...
