Research Topics
| Mepur H RavindranathSummaryAffiliation: John Wayne Cancer Institute Country: USA Publications
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Detail Information
Publications
Serum total gangliosides and TA90-IC levels: novel immunologic markers in colorectal cancerCarlos A Perez
Laboratory of Glyco-Immunotherapy, John Wayne Cancer Institute, Santa Monica, California 90404-23023, USA
Cancer J 8:55-61. 2002..The potential prognostic significance of TA90-IC status in advanced disease warrants further investigation...- Anticancer therapeutic potential of soy isoflavone, genisteinMepur H Ravindranath
Laboratory of Glycoimmunotherapy, John Wayne Cancer Institute, 2200 Santa Monica Blvd, Santa Monica, CA 90404 2302, USA
Adv Exp Med Biol 546:121-65. 2004..Several biotechnological firms in Japan, Australia and in the United States (e.g., Nutrilite) manufacture genistein as a natural supplement under quality controlled and assured conditions... - Immunogenic gangliosides in human ovarian carcinomaMepur H Ravindranath
Laboratory of Glycoimmunotherapy, John Wayne Cancer Institute at Saint John s Health Center, 2200 Santa Monica Boulevard, Santa Monica, CA 90404 2302, USA
Biochem Biophys Res Commun 353:251-8. 2007..The significance of the endogenous IgM response to GD1a may be to eliminate this immunosuppressive-ganglioside from the tumor-microenvironment... - Endogenous immune response to gangliosides in patients with confined prostate cancerMepur H Ravindranath
Laboratory of Glycoimmunotherapy, John Wayne Cancer Institute, Santa Monica, CA 90404, USA
Int J Cancer 116:368-77. 2005.... - Significance of endogenous augmentation of antiganglioside IgM in cancer patients: potential tool for early detection and management of cancer therapyMepur H Ravindranath
Department of Glycoimmunotherapy, John Wayne Cancer Institute, 2200 Santa Monica Blvd, Santa Monica, CA 90404 2302, USA
Ann N Y Acad Sci 1107:212-22. 2007..This tailored approach to immunotherapy could be incorporated in postoperative adjuvant protocols... - Glycoimmunomics of human cancer: current concepts and future perspectivesMepur H Ravindranath
Department of Glycoimmunotherapy, John Wayne Cancer Institute, Saint John s Health Center, Santa Monica, CA 90404 2302, USA
Future Oncol 3:201-14. 2007..This review describes the unique immunomics of tumor-associated glycoantigens and explains why the field of glycoimmunomics may yield clinically important biomarkers and treatments for the management of human cancer... - Gangliosides of organ-confined versus metastatic androgen-receptor-negative prostate cancerMepur H Ravindranath
Laboratory of Glycoimmunotherapy, John Wayne Cancer Institute, 2200 Santa Monica Blvd, Santa Monica, CA 90404 2302, USA
Biochem Biophys Res Commun 324:154-65. 2004..G2a-reactive ganglioside, two alkali-susceptible, and three alkali-resistant GMR17-reactive gangliosides makes HH870 a potential component of a polyvalent-vaccine for active-specific immunotherapy of CaP... - Human antiganglioside autoantibodies: validation of ELISAMepur H Ravindranath
Laboratory of Glycoimmunotherapy, John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404 2302, USA
Ann N Y Acad Sci 1050:229-42. 2005..The validated protocol also must include a simple formula to estimate titers for several replicas. Finally, antibody titers must be converted to natural logs for statistical appraisal... - Cryosurgical ablation of liver tumors in colon cancer patients increases the serum total ganglioside level and then selectively augments antiganglioside IgMMepur H Ravindranath
Laboratory of Glycoimmunotherapy, John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404 2302, USA
Cryobiology 45:10-21. 2002..The post-CSA decline in the STG level correlated with the increase in the antibodies, suggesting a homeostatic role of the antibodies... - Serum anti-ganglioside IgM antibodies in soft tissue sarcoma: clinical prognostic implicationsCarlos A Perez
Department of Glycoimmunotherapy, Roy E. Coats Research Laboratories, John Wayne Cancer Institute at Saint John's Health Center, Santa Monica, California 90404-2302, USA
Cancer J 8:384-94. 2002..Anti-GD1a and anti-GT1b IgM titers predicted survival and may be of therapeutic and prognostic value in the management of soft tissue sarcoma... - Ganglioside signatures of primary and nodal metastatic melanoma cell lines from the same patientMepur H Ravindranath
Department of Glycoimmunotherapy, John Wayne Cancer Institute, Santa Monica, California, USA
Melanoma Res 18:47-55. 2008..The cell lines from thyroid, spleen and jejunum expressed O-AcGD2. In all metastatic melanoma cell lines GD1a is more prevalent than GD3, suggesting that GD1a may be a major melanoma-ganglioside... - Serum total ganglioside level correlates with clinical course in melanoma patients after immunotherapy with therapeutic cancer vaccineMepur H Ravindranath
Laboratory of GlycolImmunotherapy, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, California 90404, USA
J Immunother 26:277-85. 2003..The data suggest that sTG level could be a potential tool for assessing the response to immunotherapy in melanoma patients by week 24... - Increased levels of gangliosides in the plasma and ascitic fluid of patients with advanced ovarian cancerAlessandro D Santin
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
BJOG 111:613-8. 2004..Secretion of gangliosides may play an important role in the inhibition of anti-tumour immune function commonly observed in advanced ovarian cancer... - Monitoring response to treatment in melanoma patients: potential of a serum glycomic markerSenthamil R Selvan
Cell Biology Laboratory, Hoag Cancer Center, Newport Beach, CA 92663, USA
Int J Cancer 122:1374-83. 2008..Clinical correlations of sTG indicate that sTG-downregulating therapy may be an effective treatment strategy for melanoma...