Research Topics
| K S KornmanSummaryAffiliation: Interleukin Genetics Country: USA Publications
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Detail Information
Publications
Diagnostic and prognostic tests for oral diseases: practical applicationsKenneth S Kornman
Interleukin Genetics, 135 Beaver Street, Third Floor, Waltham, MA 02452, USA
J Dent Educ 69:498-508. 2005..The use of diagnostic and prognostic tests and their application to the assessment and management of dental caries and periodontitis are the focus of this review...
Mapping the pathogenesis of periodontitis: a new lookKenneth S Kornman
Interleukin Genetics, 135 Beaver Street, Waltham, MA 02452, USA
J Periodontol 79:1560-8. 2008..It is hoped that improved conceptual models of pathogenesis will assist in focusing new research and speed the translation of new data into practical applications...
Interleukin-1 genotype-selective inhibition of inflammatory mediators by a botanical: a nutrigenetics proof of conceptKenneth Kornman
Interleukin Genetics, Waltham, Massachusetts, USA
Nutrition 23:844-52. 2007....
Interleukin 1 genetics, inflammatory mechanisms, and nutrigenetic opportunities to modulate diseases of agingKenneth S Kornman
Interleukin Genetics Incorporated, Waltham, MA 02452, USA
Am J Clin Nutr 83:475S-483S. 2006..One of the most practical applications of nutritional modulation of chronic disease may be nutrients that regulate the expression of key inflammatory genes...
Genetic variations and inflammation: a practical nutrigenomics opportunityKenneth S Kornman
Interleukin Genetics, Waltham, MA 02452, USA
Nutrition 20:44-9. 2004
Candidate genes as potential links between periodontal and cardiovascular diseasesK S Kornman
Interleukin Genetics, Inc, Waltham, Massachusetts, USA
Ann Periodontol 6:48-57. 2001..This review will consider biological mechanisms and genes that may be reasonable candidates for an etiological mechanism that influences the clinical characteristics of both periodontal disease and cardiovascular disease...
Patients are not equally susceptible to periodontitis: does this change dental practice and the dental curriculum?K S Kornman
Interleukin Genetics, Inc, Waltham, MA 02452, USA
J Dent Educ 65:777-84. 2001..This review will discuss the evidence that supports the change in our knowledge and understanding of periodontal disease. The question now becomes at what point, and how, do we integrate this new knowledge into the dental curriculum?..
Interleukin-1 genotypes and the association between periodontitis and cardiovascular diseaseK S Kornman
Interleukin Genetics, Inc, San Antonio, Texas, USA
J Periodontal Res 34:353-7. 1999..Studies of IL-1 gene polymorphisms, atherosclerotic plaque instability and cardiovascular clinical events are in progress. Hypothetical models are presented to explain how IL-1 genetic factors may be involved in cardiovascular disease...
Bringing light to the heat: "inflammation and periodontal diseases: a reappraisal"Kenneth S Kornman
Interleukin Genetics, Waltham, MA, USA
J Periodontol 79:1313. 2008
C-reactive protein levels are influenced by common IL-1 gene variationsPeter Berger
Division of Cardiovascular Disease, Mayo Clinic, Rochester, Minnesota 55905, USA
Cytokine 17:171-4. 2002..These data indicate that IL-1 gene polymorphisms known to affect the inflammatory response are highly related to plasma levels of CRP and fibrinogen in patients referred for coronary angiography...
Nutritional genomics in practice: where do we begin?Ruth M DeBusk
J Am Diet Assoc 105:589-98. 2005..The future of dietetics is unquestionably intertwined with nutritional genomics...
Inflammation and factors that may regulate inflammatory responseThomas E Van Dyke
Department of Periodontology and Oral Biology, Boston University Goldman School of Dental Medicine, 100 E Newton Street, Boston, MA 02118, USA
J Periodontol 79:1503-7. 2008..Greater understanding of the complex pathways involved in inflammation may provide alternative therapeutic strategies to combat inflammation and chronic diseases potentially arising from it...
Host modulation as a therapeutic strategy in the treatment of periodontal diseaseK S Kornman
Medical Science Systems, Inc, and The University of Texas Health Science Center at San Antonio, USA
Clin Infect Dis 28:520-6. 1999..Improved knowledge of bacterium-host interactions and of the processes leading to tissue destruction will help to identify targets for host modulation to reduce periodontitis in selected situations...
IL-1 gene polymorphism and smoking as risk factors for peri-implant bone loss in a well-maintained populationAndreas Feloutzis
Department of Periodontology, University of Berne, Switzerland
Clin Oral Implants Res 14:10-7. 2003....
IL1B gene promoter haplotype pairs predict clinical levels of interleukin-1beta and C-reactive proteinJohn Rogus
Interleukin Genetics Inc, 135 Beaver Street, Waltham, MA, 02452, USA
Hum Genet 123:387-98. 2008..These findings may apply to other inducible genes and could provide a logical framework for exploring disease risk related to genetic variability in pathogenic mediators...
Single nucleotide polymorphisms in the human interleukin-1B gene affect transcription according to haplotype contextHongmin Chen
Interleukin Genetics Inc, 135 Beaver Street, Waltham, MA 02452, USA
Hum Mol Genet 15:519-29. 2006..This finding underlines the importance of understanding the haplotype structure of populations used for genetic studies and may be especially important in the functional analysis of genetic variation across gene regulatory regions...
Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular eventsSotirios Tsimikas
Division of Cardiovascular Diseases, University of California, San Diego, CA, USA
J Lipid Res 48:425-33. 2007..In conclusion, IgG and IgM OxLDL biomarkers have divergent associations with CAD in univariate analysis but are not independent predictors of CAD or clinical events...
