Alexander B Niculescu

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. ncbi Genomic studies of mood disorders -- the brain as a muscle?
    Alexander B Niculescu
    Institute of Psychiatric Research, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202 4887, USA
    Genome Biol 6:215. 2005
  2. ncbi PhenoChipping of psychotic disorders: a novel approach for deconstructing and quantitating psychiatric phenotypes
    Alexander B Niculescu
    Laboratory of Neurophenomics, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Am J Med Genet B Neuropsychiatr Genet 141:653-62. 2006
  3. ncbi Polypharmacy in oligopopulations: what psychiatric genetics can teach biological psychiatry
    Alexander B Niculescu
    Laboratory of Neurophenomics, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Psychiatr Genet 16:241-4. 2006
  4. ncbi Mindscape: a convergent perspective on life, mind, consciousness and happiness
    Alexander B Niculescu
    Indiana University School of Medicine, Institute of Psychiatric Research, 791 Union Drive, Indianapolis, IN 46202 4887, USA
    J Affect Disord 123:1-8. 2010
  5. ncbi Evidence for genetic association of RORB with bipolar disorder
    Casey L McGrath
    Department of Psychiatry, Laboratory of Neurophenomics, Indiana University School of Medicine, Indianapolis, IN, USA
    BMC Psychiatry 9:70. 2009
  6. ncbi Convergent integration of animal model and human studies of bipolar disorder (manic-depressive illness)
    Helen Le-Niculescu
    Department of Psychiatry, Indiana University School of Medicine, Indianapolis VA Medical Center, Indianapolis, IN 46202, USA
    Curr Opin Pharmacol 10:594-600. 2010

Detail Information

Publications6

  1. ncbi Genomic studies of mood disorders -- the brain as a muscle?
    Alexander B Niculescu
    Institute of Psychiatric Research, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202 4887, USA
    Genome Biol 6:215. 2005
    ..Similar molecular pathways, volumetric changes, and the effects of exercise on mood suggest a superficial analogy, and perhaps a deeper relationship, between muscle and brain functioning...
  2. ncbi PhenoChipping of psychotic disorders: a novel approach for deconstructing and quantitating psychiatric phenotypes
    Alexander B Niculescu
    Laboratory of Neurophenomics, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Am J Med Genet B Neuropsychiatr Genet 141:653-62. 2006
    ..Empirically derived clusterings of (endo)phenotypes and of patients will better serve genetic, pharmacological, and imaging research, as well as clinical practice...
  3. ncbi Polypharmacy in oligopopulations: what psychiatric genetics can teach biological psychiatry
    Alexander B Niculescu
    Laboratory of Neurophenomics, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Psychiatr Genet 16:241-4. 2006
    ..We propose that current developments in genetics and genomics point to an Early Low-Dose Rational Polypharmacy in Oligopopulations model for psychiatric pharmacotherapy...
  4. ncbi Mindscape: a convergent perspective on life, mind, consciousness and happiness
    Alexander B Niculescu
    Indiana University School of Medicine, Institute of Psychiatric Research, 791 Union Drive, Indianapolis, IN 46202 4887, USA
    J Affect Disord 123:1-8. 2010
    ....
  5. ncbi Evidence for genetic association of RORB with bipolar disorder
    Casey L McGrath
    Department of Psychiatry, Laboratory of Neurophenomics, Indiana University School of Medicine, Indianapolis, IN, USA
    BMC Psychiatry 9:70. 2009
    ..Here we report association studies between bipolar disorder and single-nucleotide polymorphisms (SNPs) in RORA and RORB...
  6. ncbi Convergent integration of animal model and human studies of bipolar disorder (manic-depressive illness)
    Helen Le-Niculescu
    Department of Psychiatry, Indiana University School of Medicine, Indianapolis VA Medical Center, Indianapolis, IN 46202, USA
    Curr Opin Pharmacol 10:594-600. 2010
    ..Such work in psychiatry can provide an example of how to address other genetically complex disorders, and in turn will benefit by incorporating concepts from other areas, such as cancer biology and diabetes...