Research Topics
| Wei ZhangSummaryAffiliation: Illinois Institute of Technology Country: USA Publications
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Detail Information
Publications
Probing genomic diversity and evolution of Escherichia coli O157 by single nucleotide polymorphismsWei Zhang
Foodborne and Diarrheal Diseases Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Genome Res 16:757-67. 2006..Functional characterization of nucleotide polymorphisms should shed new insights on the evolution, epidemiology, and pathogenesis of STEC O157 and related pathogens...
Identification of a new gene encoding EPSPs with high glyphosate resistance from the metagenomic libraryDan Jin
College of Life Sciences, Key Laboratory of Bio resources and Eco environment, The Ministry of Education, Sichuan University, 610064, Chengdu, China
Curr Microbiol 55:350-5. 2007..A His-tagged RD fusion protein was produced into E. coli to characterize the enzymatic properties of the RD EPSP protein...
Variation in virulence among clades of Escherichia coli O157:H7 associated with disease outbreaksShannon D Manning
Microbial Evolution Laboratory, National Food Safety and Toxicology Center, Michigan State University, East Lansing, MI 48824, USA
Proc Natl Acad Sci U S A 105:4868-73. 2008..The ability to detect and rapidly genotype O157 strains belonging to such lineages is important and will have a significant impact on both disease diagnosis and treatment guidelines...
Probing the pan-genome of Listeria monocytogenes: new insights into intraspecific niche expansion and genomic diversificationXiangyu Deng
National Center for Food Safety and Technology, Illinois Institute of Technology, Summit, Illinois 60501, USA
BMC Genomics 11:500. 2010..Two of these lineages predominantly cause human sporadic and epidemic infections, whereas the third lineage has never been implicated in human disease outbreaks despite its overall conservation of many known virulence factors...
Efficient oligonucleotide probe selection for pan-genomic tiling arraysAdam M Phillippy
Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA
BMC Bioinformatics 10:293. 2009..Prior microarrays have included only a single strain per array or the conserved sequences of gene families. These arrays omit potentially important genes and sequence variants from the pan-genome...
Functional analysis of ycfR and ycfQ in Escherichia coli O157:H7 linked to outbreaks of illness associated with fresh produceKaiping Deng
U S Food and Drug Administration, National Center for Food Safety and Technology, 6502 S Archer Rd, Summit Argo, IL 60501, USA
Appl Environ Microbiol 77:3952-9. 2011..These findings suggest that gene regulation may be a mechanism by which E. coli O157:H7 strain Sakai could survive in the postharvest processing environment...
Transcriptomic responses of Salmonella enterica serovars Enteritidis and Typhimurium to chlorine-based oxidative stressSiyun Wang
National Center for Food Safety and Technology, Illinois Institute of Technology, Summit Argo, IL 60501, USA
Appl Environ Microbiol 76:5013-24. 2010..enterica resistant or susceptible to certain types of environmental stresses, which in turn promotes the development of more effective hurdle interventions to reduce the risk of S. enterica contamination in the food supply...
Transcriptomic response of Listeria monocytogenes during the transition to the long-term-survival phaseJia Wen
Department of Food Science, Pennsylvania State University, University Park, Pennsylvania 16802, USA
Appl Environ Microbiol 77:5966-72. 2011..94), as the LTS cells rapidly resume metabolic activities and transit back to log phase with decreased baro- and thermotolerance...
A novel gene detection method based on period-3 propertyLun Huang
Department of Electrical and Computer Engineering, Illinois Institute of Technology, Chicago, 60616, USA
Conf Proc IEEE Eng Med Biol Soc 2009:3857-60. 2009..These approaches result in improved computational techniques for the solution of useful problems in genomic information science and technology...
Survival and heat resistance of Salmonella enterica and Escherichia coli O157:H7 in peanut butterYingshu He
Institute for Food Safety and Health, Illinois Institute of Technology, 6502 South Archer Road, Bedford Park, IL 60501, USA
Appl Environ Microbiol 77:8434-8. 2011..High carbohydrate content in peanut butter and low incubation temperature resulted in higher levels of bacterial survival during storage but lower levels of bacterial resistance to heat treatment...
Transcriptome sequencing of Salmonella enterica serovar Enteritidis under desiccation and starvation stress in peanut oilXiangyu Deng
Institute for Food Safety and Health, Illinois Institute of Technology, 6502 S Archer Rd, Bedford Park, IL 60501, USA
Food Microbiol 30:311-5. 2012..In addition, non-coding RNAs may also play roles in Salmonella desiccation stress response. This is the first report of using RNA-seq technology in characterizing bacterial transcriptomes in a food matrix...
Transcriptomic response of Escherichia coli O157:H7 to oxidative stressSiyun Wang
National Center for Food Safety and Technology, Illinois Institute of Technology, Chicago, Illinois, USA
Appl Environ Microbiol 75:6110-23. 2009....
Multi-virulence-locus sequence typing identifies single nucleotide polymorphisms which differentiate epidemic clones and outbreak strains of Listeria monocytogenesYi Chen
Department of Food Science, The Pennsylvania State University, University Park, PA 16802, USA
J Clin Microbiol 45:835-46. 2007..monocytogenes. SNPs in virulence genes appear to be excellent molecular markers for the epidemiological investigation of epidemics and outbreaks caused by L. monocytogenes...
Evaluation of genetic variation contributing to differences in gene expression between populationsWei Zhang
Department of Medicine, The University of Chicago, Chicago, IL 60637, USA
Am J Hum Genet 82:631-40. 2008..We also provide an evaluation of the contributions of genetic variation and nongenetic factors to the population differences in gene expression...
Identification and molecular analysis of the highly pathogenic duck hepatitis virus type 1 in Hubei province of ChinaXin Jin
College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, People s Republic of China
Res Vet Sci 85:595-8. 2008..The new-identified JX strain was grouped into one lineage with A66 and C80 strains, which were also isolated from China...
The PIT1 gene polymorphisms were associated with chicken growth traitsQinghua Nie
Department of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, Guangzhou 510642, Guangdong, China
BMC Genet 9:20. 2008..In this study, five reported polymorphisms (MR1-MR5) of the PIT1 gene were genotyped in a full sib F2 resource population to evaluate their effects on growth, carcass and fatty traits in chickens...
Gene expression in the developing diaphragm: significance for congenital diaphragmatic herniaRobin D Clugston
University of Alberta, Department of Physiology, Edmonton, Alberta, Canada
Am J Physiol Lung Cell Mol Physiol 294:L665-75. 2008....
Genetic analysis of attractin homologsWill P Walker
Department of Biomedical Sciences, Cornell University, Ithaca, New York 14853, USA
Genesis 45:744-56. 2007..Thus, the two genes are redundant from the perspective of gain-of-function but not loss-of-function mutations...
Genome-wide association analyses of expression phenotypesGary K Chen
Department of Epidemiology and Biostatistics, Institute for Human Genetics, University of California at San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
Genet Epidemiol 31:S7-S11. 2007..Finally, for datasets with small sample sizes but a large number of features like the Genetic Analysis Workshop 15 dataset, machine learning approaches may be more practical than traditional parametric approaches...
Immunoproteomics of extracellular proteins of Chinese virulent strains of Streptococcus suis type 2Wei Zhang
Key Laboratory of Animal Disease Diagnostic and Immunology, Ministry of Agriculture, Nanjing Agricultural University, Nanjing, China
Proteomics 7:4468-76. 2007..Genes for six of the differentially expressed proteins were found in both virulent strains, and of those were present in the avirulent stain...
A comparative study on the phylogenetic diversity of culturable actinobacteria isolated from five marine sponge speciesHaitao Zhang
Marine Bioproducts Engineering Group, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China
Antonie Van Leeuwenhoek 93:241-8. 2008..Sponge species have been demonstrated here to vary as sources of culturable actinobacterial diversity, and the methods for sampling such diversity presented may be useful for improved sampling of such diversity...
Single-nucleotide polymorphisms at the TP53-binding or responsive promoter regions of BAX and BCL2 genes and risk of squamous cell carcinoma of the head and neckKexin Chen
Department of Epidemiology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Carcinogenesis 28:2008-12. 2007..Our data suggest that the risk of SCCHN may be associated with these two SNPs of BAX and BCL2 promoter regions, particularly among TP53 heterozygotes. Larger studies are needed to validate these findings...
Random local neighbor joining: a new method for reconstructing phylogenetic treesWei Zhang
Institute of Bioinformatics and Systems Biology, MOE Key Laboratory of Bioinformatics, State Key Laboratory of Biomembrane and Membrane Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, China
Mol Phylogenet Evol 47:117-28. 2008..Thus, the number of different topologies and the proportion of "most frequent topology" can be used as auxiliary criteria to evaluate reliability of a phylogenetic tree...
A single residue mutation of 5-enoylpyruvylshikimate-3-phosphate synthase in Pseudomonas stutzeri enhances resistance to the herbicide glyphosateAimin Liang
College of Biological Sciences, China Agricultural University, Beijing 100094, PR China
Biotechnol Lett 30:1397-401. 2008..The effect of the single residue mutation on glyphosate resistance was also analyzed using a computer-based three-dimensional model...
The Arabidopsis MutS homolog AtMSH5 is required for normal meiosisXiaoduo Lu
School of Life Sciences, Lanzhou University, Lanzhou 730000, China
Cell Res 18:589-99. 2008..Taken together, the evidence indicates that AtMSH5 promotes homologous recombination through facilitating chiasma formation during prophase I in Arabidopsis...
Genome-wide analysis of the cyclin family in Arabidopsis and comparative phylogenetic analysis of plant cyclin-like proteinsGuanfang Wang
Department of Biology and the Huck Institutes of Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, USA
Plant Physiol 135:1084-99. 2004..Our study provides an opportunity to rapidly assess the position of plant cyclin genes in terms of evolution and classification, serving as a guide for further functional study of plant cyclins...
Culture-independent nested PCR method reveals high diversity of actinobacteria associated with the marine sponges Hymeniacidon perleve and Sponge spYanjuan Xin
Marine Bioproducts Engineering Group, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China
Antonie Van Leeuwenhoek 94:533-42. 2008..The presence of Acidimicrobium and mycobacteria within two sponges can lay the groundwork for attempts to culture these interesting bacteria for industrial applications...
Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 geneFederico Innocenti
Department of Medicine, The University of Chicago, Chicago, IL 60637, USA
Pharmacogenet Genomics 18:683-97. 2008..The genetic basis of interindividual variability in UGT2B7 function is unknown. This study aimed to discover novel gene variants of functional significance...
Y chromosome haplogroups may confer susceptibility to partial AZFc deletions and deletion effect on spermatogenesis impairmentYuan Yang
Department of Medical Genetics, West China Hospital, West China Medical School and State Key Laboratory of Biotherapy, Sichuan University, Gaopeng Street, Keyuan Road 4, Chengdu, Sichuan 610041, People s Republic of China
Hum Reprod 23:2167-72. 2008..With this in mind, we investigated the possible association between Y chromosome haplogroups and predisposition to partial AZFc deletions and their effect on spermatogenesis in a Chinese population...
High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinomaXiao Dong Zhu
Liver Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai 200032, China
J Clin Oncol 26:2707-16. 2008..To investigate prognostic values of the intratumoral and peritumoral expression of macrophage colony-stimulating factors (M-CSF) in hepatocellular carcinoma (HCC) patients after curative resection...
Identification of genetic variants and gene expression relationships associated with pharmacogenes in humansRong Stephanie Huang
Section of Hematology Oncology, Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
Pharmacogenet Genomics 18:545-9. 2008..Our objective was to identify single nucleotide polymorphisms (SNPs) that potentially affected the expression of these genes or potential SNP-gene interactions involved to improve our understanding of genetic effects on drug therapy...
Nitrogen fixation island and rhizosphere competence traits in the genome of root-associated Pseudomonas stutzeri A1501Yongliang Yan
Biotechnology Research Institute, National Key Facility for Crop Gene Resources and Genetic Improvement, Chinese Academy of Agricultural Sciences, Beijing 100081, China
Proc Natl Acad Sci U S A 105:7564-9. 2008....
Evolution from heterozygous to homozygous KIT mutation in gastrointestinal stromal tumor correlates with the mechanism of mitotic nondisjunction and significant tumor progressionLei L Chen
Department of Internal Medicine, Division of Hematology Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA
Mod Pathol 21:826-36. 2008....
Gene cloning and expression analysis of ubiquitin derived from Musca domesticaQian Ren
School of Life Sciences, Shandong University, Jinan, Shandong 250100, China
Arch Insect Biochem Physiol 68:89-99. 2008..After infection with gram-negative and gram-positive bacteria, Mub(S27) transcript level was upregulated. Mub(S27) transcript level was also regulated by heat or cold stress...
Polymorphisms in microRNA targets: a gold mine for molecular epidemiologyKexin Chen
Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Hospital and Institute, Tianjin 300060, People s Republic of China
Carcinogenesis 29:1306-11. 2008..The biological relevance of these polymorphisms in predicted microRNA-binding sites is beginning to be examined in large case-control studies...
Mutation screening and association study of the TSSK4 Gene in Chinese infertile men with impaired spermatogenesisDan Su
Department of Medical Genetics, West China Hospital, Sichuan University, Renmin Nanlu, Chengdu, 610041, China
J Androl 29:374-8. 2008..Our investigation of TSSK4, a potentially important testicular gene, in Chinese infertile and control men identified the association of some single nucleotide polymorphisms in this gene with male infertility...
Genetic diversity and drug resistance of human immunodeficiency virus type 1 (HIV-1) strains circulating in ShanghaiPing Zhong
Department of AIDS and STD, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China
AIDS Res Hum Retroviruses 23:847-56. 2007..It is believed that this information may help to guide recommendations for diagnostic assays, vaccine design, and antiretroviral regimen strategies in China...
Analysis of bacterial foodborne disease outbreaks in China between 1994 and 2005Shijie Wang
Food Science and Technology College of Agriculture University of Hebei, Baoding, China
FEMS Immunol Med Microbiol 51:8-13. 2007..We hope that this review can be compared to reviews from other regions of the world, in an attempt to prevent future outbreaks from occurring...
The common variant N372H in BRCA2 gene may be associated with idiopathic male infertility with azoospermia or severe oligozoospermiaA Zhoucun
Department of Medical Genetics, West China Hospital, Sichuan University, and Division of Human Morbid Genomics, National Key Laboratory of Biotherapy, Chengdu 610041, PR China
Eur J Obstet Gynecol Reprod Biol 124:61-4. 2006..To explore the possible association between the common single nucleotide polymorphism N372H in human breast cancer susceptibility gene 2 (BRCA2) and the idiopathic male infertility with azoospermia or severe oligozoospermia...
Multi-virulence-locus sequence typing clarifies epidemiology of recent listeriosis outbreaks in the United StatesYi Chen
Department of Food Science, The Pennsylvania State University, University Park, PA 16802, USA
J Clin Microbiol 43:5291-4. 2005..MVLST demonstrated high epidemiological relevance and indicated that the two outbreaks were the result of one epidemic...
Chromosome-encoded gene cluster for the metabolic pathway that converts aniline to TCA-cycle intermediates in Delftia tsuruhatensis AD9Quanfeng Liang
Department of Microbiology, Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 12 Zhongguancun Nandajie, Beijing 100081, P R China
Microbiology 151:3435-46. 2005..The tad gene cluster showed significant similarity in nucleotide sequence and genetic organization to the plasmid-encoded aniline degradation gene cluster of Pseudomonas putida UCC22...
MDR1 genotype do not influence the absorption of a single oral dose of 100 mg talinolol in healthy Chinese malesWei xia Zhang
Pharmacogenetics Research Institute, Institute of Clinical Pharmacology, Central South University, Changsha, Hunan 410078, China
Clin Chim Acta 359:46-52. 2005..We investigated the linkage between SNPs in exon 12 (C1236T), exon 21 (G2677T/A) and exon 26 (C3435T) of MDR1, and explored the effect of linked polymorphism on the absorption of talinolol after a single oral dose of 100 mg...
Multiplex PCR assay simplifies serotyping and sequence typing of Listeria monocytogenes associated with human outbreaksWei Zhang
Department of Food Science, Pennsylvania State University, University Park, Pennsylvania 16802 2504, USA
J Food Prot 68:1907-10. 2005..monocytogenes similar to pulsed-field gel electrophoresis analysis...
The Arabidopsis ROCK-N-ROLLERS gene encodes a homolog of the yeast ATP-dependent DNA helicase MER3 and is required for normal meiotic crossover formationChangbin Chen
Department of Biology and the Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA
Plant J 43:321-34. 2005....
Phylogenetic analysis and developmental expression of thymosin-beta4 gene in amphioxusXiangwei Huang
Department of Biology, Shandong University, Shandong, Jinan, 250100, People's Republic of China
Dev Genes Evol 215:364-8. 2005..These results are interpreted to mean that thymosin-beta4 genes might play a conserved role in the patterning of chordate embryos and functions in adults...
[The haplotypes of three single nucleotide polymorphisms in caspase-3 gene in Han nationality of Zhejiang province in China.]Yun Xie
Institute of Pathology and Forensic Medicine and Research Center of Environment Genomics, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310006 P. R. China
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 21:633-5. 2004....
Growing genetic regulatory networks from seed genesRonaldo F Hashimoto
Department of Electrical Engineering, Texas A and M University, College Station, TX, USA 77843, USA
Bioinformatics 20:1241-7. 2004..AVAILABILITY: Software for the seed-growing algorithm will be available at the website for Probabilistic Boolean Networks: http://www2.mdanderson.org/app/ilya/PBN/PBN.htm..
Preferential reduction of dicentrics in reciprocal exchanges due to the combination of the size of broken chromosome segments by radiationWei Zhang
National Institute for Radiological Protection and Nuclear Safety, Chinese Center for Disease Control and Prevention, 100088 Beijing, China
J Hum Genet 48:531-4. 2003..It was suggested that there was a special mechanism causing preferential reduction of dicentrics in reciprocal exchanges originated from the heteromorphic size of broken chromosomes in the last combination...
Rhodocista pekingensis sp. nov., a cyst-forming phototrophic bacterium from a municipal wastewater treatment plantDemin Zhang
Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, PR China
Int J Syst Evol Microbiol 53:1111-4. 2003..The major cellular quinone was Q-9. The DNA G + C content of cells was 68.8 mol%. The type strain of Rhodocista pekingensis is 3-pT (=AS 1.2194T=JCM 11689T)...
Rhodopseudomonas faecalis sp. nov., a phototrophic bacterium isolated from an anaerobic reactor that digests chicken faecesDemin Zhang
Institute of Microbiology, Chinese Academy of Sciences, Beijing 100080, P.R. China
Int J Syst Evol Microbiol 52:2055-60. 2002..Therefore, the name Rhodopseudomonas faecalis sp. nov. was proposed for the new isolates. The type strain is gc(T) ( = AS1.2176(T) = JCM 11668(T))...
Sequence and analysis of rice chromosome 4Qi Feng
National Center for Gene Research, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 500 Caobao Road, Shanghai 200233, China
Nature 420:316-20. 2002..By contrast, there is little conservation in gene order between rice and Arabidopsis...
Gene perturbation and intervention in probabilistic Boolean networksIlya Shmulevich
Cancer Genomics Laboratory, University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 85, Houston, TX 77030, USA
Bioinformatics 18:1319-31. 2002..We consider the general question of the potential effect of individual genes on the global dynamical network behavior, both from the view of random gene perturbation as well as intervention in order to elicit desired network behavior...
ASYMMETRIC LEAVES1, an Arabidopsis gene that is involved in the control of cell differentiation in leavesYue Sun
Shanghai Institute of Plant Physiology, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, China
Planta 214:694-702. 2002..High levels of AS1 expression were found in tissues with highly proliferative cells, which further suggests a role in cell division and early cell differentiation...
Single nucleotide polymorphisms of the gonadotrophin-regulated testicular helicase (GRTH) gene may be associated with the human spermatogenesis impairmentZhoucun A
Department of Medical Genetics, West China Hospital, Sichuan University, China
Hum Reprod 21:755-9. 2006..To test this hypothesis, we investigated the possible association between the variations of the GRTH gene and human spermatogenesis impairment...
The Arabidopsis thaliana PARTING DANCERS gene encoding a novel protein is required for normal meiotic homologous recombinationAsela J Wijeratne
Intercollege Graduate Program in Plant Physiology, The Pennsylvania State University, University Park, PA 16802, USA
Mol Biol Cell 17:1331-43. 2006..Comparison to other genes with limited sequence similarity raises the possibility that PTD may present a previously unknown function conserved in divergent eukaryotic organisms...
Genotypic and phenotypic characterization of Lactobacillus casei strains isolated from different ecological niches suggests frequent recombination and niche specificityHui Cai
Department of Food Science, 1605 Linden Dr, University of Wisconsin, Madison, WI 53706, USA
Microbiology 153:2655-65. 2007..casei. The L. casei population analysed in this study demonstrated both a high level of phenotypic and genotypic diversity, as well as specificity to different ecological niches...
Analysis of a genomic island housing genes for DNA S-modification system in Streptomyces lividans 66 and its counterparts in other distantly related bacteriaXinyi He
Laboratory of Microbial Metabolism and School of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai 200030, China
Mol Microbiol 65:1034-48. 2007..Comparison of dnd clusters in the 12 bacteria strongly suggests that these dnd-bearing elements might have evolved from a common ancestor similar to plasmid-originated chromosome II of Pseudoalteromonas haloplanktis TAC125...
Polymorphic TP53BP1 and TP53 gene interactions associated with risk of squamous cell carcinoma of the head and neckKexin Chen
Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Clin Cancer Res 13:4300-5. 2007....
The breeding of two polyploid rice lines with the characteristic of polyploid meiosis stabilityDeTian Cai
College of Life Science, Hubei University, Wuhan, 430062, China
Sci China C Life Sci 50:356-66. 2007..The selection of PMeS lines is the first step in polyploid rice breeding; their use will advance the progress of polyploid rice breeding, which will in turn offer a new way to breed super rice...
Developmental expression of amphioxus RACK1Xiangwei Huang
Institute of Developmental Biology, College of Life Science, China
Sci China C Life Sci 50:329-34. 2007..Its expression in cerebral vesicles and neural tubes was also weaker or disappeared. In the adult animal, AmphiRACK1 transcripts were detected in the epithelium of midgut diverticulus and gut, wheel organ, gill blood vessels and testis...
A genome-wide approach to identify genetic variants that contribute to etoposide-induced cytotoxicityR Stephanie Huang
Section of Hematology Oncology, Biostatistics Consulting Laboratory, Department of Health Studies, University of Chicago, Chicago, IL 60637, USA
Proc Natl Acad Sci U S A 104:9758-63. 2007..This unbiased method can be used to elucidate genetic variants contributing to a wide range of cellular phenotypes induced by chemotherapeutic agents...
Phylogenetic analysis and expression pattern of the AmphiCaBP-like gene from amphioxus, encoding a novel member of the calmodulin-like subfamilyBaojun Li
Life Science School, Institute of Developmental Biology, Shandong University, China
DNA Seq 18:228-34. 2007..In adult amphioxus, the transcripts are found in the epithelial cells of the gut and midgut diverticulus, the wall of coelom, the branchia, the neural cord and gonads...
The 1p-encoded protein stathmin and resistance of malignant gliomas to nitrosoureasTeri T B Ngo
Surgical and Molecular Neuro oncology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
J Natl Cancer Inst 99:639-52. 2007....
Characterization of frequently deleted 6q locus in prostate cancerMei Sun
Center for Prostate Disease Research, Department of Surgery, Uniformed Services University of the Health Sciences, Rockville, Maryland 20832, USA
DNA Cell Biol 25:597-607. 2006..1, and deletions of this locus are frequently associated with prostate tumorigenesis. In the light of emerging role of noncoding RNAs in cancer biology including CaP, future investigations of 6qTSG11 locus is warranted...
Single nucleotide polymorphism C677T in the methylenetetrahydrofolate reductase gene might be a genetic risk factor for infertility for Chinese men with azoospermia or severe oligozoospermiaZhou Cun A
Department of Medical Genetics, West China Hospital, Sichuan University, Chengdu 610041, China
Asian J Androl 9:57-62. 2007....
Culturable actinobacteria from the marine sponge Hymeniacidon perleve: isolation and phylogenetic diversity by 16S rRNA gene-RFLP analysisHaitao Zhang
Marine Bioproducts Engineering Group, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China
Antonie Van Leeuwenhoek 90:159-69. 2006..The dominant genus was Streptomyces, which represented 74% of the isolates. Three of the strains identified are candidates for new species...
Cloning, chromosome mapping and expression analysis of an R2R3-MYB gene under-expressed in maize hybridChuanli Ju
National Maize Improvement Center of China, China Agricultural University, Yuanmingyuan West Road, Haidian, 100094 Beijing, China
Mol Biol Rep 33:103-10. 2006..A possible role of ZmMYBL1 and its relation to maize heterosis were discussed based on these results...
Effect of SLCO1B1 genetic polymorphism on the pharmacokinetics of nateglinideWei Zhang
Pharmacogenetics Research Institute, Institute of Clinical Pharmacology, Central South University, Changsha, Hunan, PR China
Br J Clin Pharmacol 62:567-72. 2006..Our objective was to assess the association between single nucleotide polymorphisms (SNPs) of SLCO1B1 and the pharmacokinetics of nateglinide...
Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese malesWei Zhang
Pharmacogenetics Research Institute, Institute of Clinical Pharmacology, Central South University, Changsha, Hunan 410078, P R China
Clin Chim Acta 373:99-103. 2006..Our objective was to determine the association between the most frequent single nucleotide polymorphisms (SNPs) of the BCRP (421C>A) and the pharmacokinetics of rosuvastatin...
A novel microsatellite within intron 8 in caspase10 gene in Chinese of Han nationalityYue-fang Ye
Institute of Pathology and Forensic Medicine and Research Center of Environment Enomics, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310006, P.R. China
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 23:16-8. 2006..The significance of the microsatellite in CASP10 gene in Chinese of Han nationality remains to be elucidated...
NYD-SP6, a novel gene potentially involved in regulating testicular development/spermatogenesisJunhua Xiao
Laboratory of Reproduction Medicine, Nanjing Medical University, Nanjing, 210029, People s Republic of China
Biochem Biophys Res Commun 291:101-10. 2002..Taken together, these results suggest that the putative protein of NYD-SP6 may play an important role in stimulating transcription involved in testicular development and/or spermatogenesis...
