B V Howard

Summary

Country: USA

Publications

  1. ncbi Diabetes-specific genetic effects on obesity traits in American Indian populations: the Strong Heart Family Study
    Nora Franceschini
    Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA
    BMC Med Genet 9:90. 2008
  2. ncbi Genetic and other factors determining mannose-binding lectin levels in American Indians: the Strong Heart Study
    Lyle G Best
    Missouri Breaks Industries Research Inc, Timber Lake, SD, USA
    BMC Med Genet 10:5. 2009
  3. ncbi Progression of coronary calcification in healthy postmenopausal women
    Judith Hsia
    Department of Medicine, The George Washington University, Washington, DC 20037, USA
    BMC Cardiovasc Disord 4:21. 2004
  4. ncbi Effect of lower targets for blood pressure and LDL cholesterol on atherosclerosis in diabetes: the SANDS randomized trial
    Barbara V Howard
    MedStar Research Institute, 6495 New Hampshire Ave, Suite 201, Hyattsville, MD 20783, USA
    JAMA 299:1678-89. 2008
  5. ncbi Coronary heart disease risk equivalence in diabetes depends on concomitant risk factors
    Barbara V Howard
    MedStar Research Institute, Washington, DC, USA
    Diabetes Care 29:391-7. 2006
  6. ncbi C-Reactive protein, insulin resistance, and metabolic syndrome in a population with a high burden of subclinical infection: insights from the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study
    Barbara V Howard
    MedStar Research Institute, Hyattsville, Maryland, USA
    Diabetes Care 31:2312-4. 2008
  7. ncbi Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial
    Barbara V Howard
    MedStar Research Institute Howard University, Washington, DC, USA
    JAMA 295:655-66. 2006
  8. ncbi Low-fat dietary pattern and weight change over 7 years: the Women's Health Initiative Dietary Modification Trial
    Barbara V Howard
    MedStar Research Institute, Washington, DC, USA
    JAMA 295:39-49. 2006
  9. ncbi A genetic and epidemiologic study of cardiovascular disease in Alaska natives (GOCADAN): design and methods
    Barbara V Howard
    MedStar Research Institute, Washington, DC, USA
    Int J Circumpolar Health 64:206-21. 2005
  10. ncbi Obesity and dyslipidemia
    Barbara V Howard
    MedStar Research Institute, 6495 New Hampshire Avenue, Suite 201, Hyattsville, MD 20783, USA
    Endocrinol Metab Clin North Am 32:855-67. 2003

Research Grants

  1. Genetics of Coronary Artery Disease in Alaska Natives (*
    Barbara Howard; Fiscal Year: 2006
  2. Cardiovascular Disease in Pima Indians
    Barbara Howard; Fiscal Year: 2007

Detail Information

Publications105 found, 100 shown here

  1. ncbi Diabetes-specific genetic effects on obesity traits in American Indian populations: the Strong Heart Family Study
    Nora Franceschini
    Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA
    BMC Med Genet 9:90. 2008
    ..1.4)...
  2. ncbi Genetic and other factors determining mannose-binding lectin levels in American Indians: the Strong Heart Study
    Lyle G Best
    Missouri Breaks Industries Research Inc, Timber Lake, SD, USA
    BMC Med Genet 10:5. 2009
    ..The genetic control of MBL2 expression is complex and genetic background effects in specific populations are largely unknown...
  3. ncbi Progression of coronary calcification in healthy postmenopausal women
    Judith Hsia
    Department of Medicine, The George Washington University, Washington, DC 20037, USA
    BMC Cardiovasc Disord 4:21. 2004
    ..This study prospectively evaluated rates and determinants of progression of coronary artery calcium score in a group of healthy postmenopausal women...
  4. ncbi Effect of lower targets for blood pressure and LDL cholesterol on atherosclerosis in diabetes: the SANDS randomized trial
    Barbara V Howard
    MedStar Research Institute, 6495 New Hampshire Ave, Suite 201, Hyattsville, MD 20783, USA
    JAMA 299:1678-89. 2008
    ..Individuals with diabetes are at increased risk for cardiovascular disease (CVD), but more aggressive targets for risk factor control have not been tested...
  5. ncbi Coronary heart disease risk equivalence in diabetes depends on concomitant risk factors
    Barbara V Howard
    MedStar Research Institute, Washington, DC, USA
    Diabetes Care 29:391-7. 2006
    ..Diabetes has been defined as a coronary heart disease (CHD) risk equivalent, and more aggressive treatment goals have been proposed for diabetic patients...
  6. ncbi C-Reactive protein, insulin resistance, and metabolic syndrome in a population with a high burden of subclinical infection: insights from the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study
    Barbara V Howard
    MedStar Research Institute, Hyattsville, Maryland, USA
    Diabetes Care 31:2312-4. 2008
    ..To explore relationships between C-reactive protein (CRP), subclinical infection, insulin resistance, and metabolic syndrome...
  7. ncbi Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial
    Barbara V Howard
    MedStar Research Institute Howard University, Washington, DC, USA
    JAMA 295:655-66. 2006
    ..Multiple epidemiologic studies and some trials have linked diet with cardiovascular disease (CVD) prevention, but long-term intervention data are needed...
  8. ncbi Low-fat dietary pattern and weight change over 7 years: the Women's Health Initiative Dietary Modification Trial
    Barbara V Howard
    MedStar Research Institute, Washington, DC, USA
    JAMA 295:39-49. 2006
    ....
  9. ncbi A genetic and epidemiologic study of cardiovascular disease in Alaska natives (GOCADAN): design and methods
    Barbara V Howard
    MedStar Research Institute, Washington, DC, USA
    Int J Circumpolar Health 64:206-21. 2005
    ..Data from this study will contribute to the delivery of health-care and prevention of CVD in Alaska Eskimos and other populations...
  10. ncbi Obesity and dyslipidemia
    Barbara V Howard
    MedStar Research Institute, 6495 New Hampshire Avenue, Suite 201, Hyattsville, MD 20783, USA
    Endocrinol Metab Clin North Am 32:855-67. 2003
    ..In addition, obese individuals should be targeted for intense lipid-lowering therapy, when necessary...
  11. ncbi Risk of cardiovascular disease by hysterectomy status, with and without oophorectomy: the Women's Health Initiative Observational Study
    Barbara V Howard
    MedStar Research Institute, Washington, DC, USA
    Circulation 111:1462-70. 2005
    ..This study compared CVD risk factors and rates between postmenopausal women who had and had not undergone hysterectomy, with or without oophorectomy...
  12. ncbi Insulin resistance and weight gain in postmenopausal women of diverse ethnic groups
    B V Howard
    MedStar Research Institute, Washington, DC 20783, USA
    Int J Obes Relat Metab Disord 28:1039-47. 2004
    ..This study was conducted to examine the influence of insulin resistance on weight change in postmenopausal women of various ethnic groups...
  13. ncbi Postmenopausal hormone therapy is associated with atherosclerosis progression in women with abnormal glucose tolerance
    Barbara V Howard
    MedStar Research Institute, 6495 New Hampshire Ave, Suite 201, Hyattsville, MD 20783, USA
    Circulation 110:201-6. 2004
    ..In this study, we hypothesized that PHT would have a worse effect on disease among women with AGT...
  14. ncbi Cardiovascular disease prevalence and its relation to risk factors in Alaska Eskimos
    Barbara V Howard
    MedStar Research Institute, Hyattsville, MD, USA
    Nutr Metab Cardiovasc Dis 20:350-8. 2010
    ..This article explores CVD prevalence and its relation to risk factors in Alaska Eskimos...
  15. ncbi The women's health initiative: a potential resource for future studies of autoimmune diseases
    Barbara V Howard
    Autoimmunity 37:265-8. 2004
    ..Given the time and expense devoted to the Women's Health initiative and these other studies, it would be of great value if researchers interested in a wide variety of chronic diseases would make use of these rich sources of data...
  16. ncbi Low-fat dietary pattern and lipoprotein risk factors: the Women's Health Initiative Dietary Modification Trial
    Barbara V Howard
    MedStar Research Institute, Hyattsville, MD 20782, USA
    Am J Clin Nutr 91:860-74. 2010
    ..The Women's Health Initiative Dietary Modification Trial tested the effects on chronic disease of a dietary pattern lower in fat and higher in vegetables, fruit, and grains...
  17. ncbi Dietary fat as a risk factor for type 2 diabetes
    Barbara V Howard
    MedStar Research Institute, Washington, District of Columbia 20010, USA
    Ann N Y Acad Sci 967:324-8. 2002
    ..The most important recommendation may be for health-care providers to carefully assess diabetes risk in their patients and institute dietary changes on an individual basis as needed to achieve and maintain body weight...
  18. ncbi Rising tide of cardiovascular disease in American Indians. The Strong Heart Study
    B V Howard
    Medlantic Research Institute and Washington Hospital Center, Washington, DC, USA
    Circulation 99:2389-95. 1999
    ..The Strong Heart Study was initiated to investigate CVD and its risk factors in American Indians in 13 communities in Arizona, Oklahoma, and South/North Dakota...
  19. ncbi Adverse effects of diabetes on multiple cardiovascular disease risk factors in women. The Strong Heart Study
    B V Howard
    Medlantic Research Institute, Washington, DC 20010 2933, USA
    Diabetes Care 21:1258-65. 1998
    ..We compared diabetes-associated differences in CVD risk factors in men and women in the Strong Heart Study, a population-based study of CVD and its risk factors in American Indians...
  20. ncbi Glycemic control in diabetic American Indians. Longitudinal data from the Strong Heart Study
    D Hu
    MedStar Research Institute, Washington, DC 20010, USA
    Diabetes Care 22:1802-7. 1999
    ....
  21. ncbi Sex may modify the effects of macronutrient intake on metabolic syndrome and insulin resistance in American Indians: the strong heart study
    Sigal Eilat-Adar
    MedStar Research Institute, Hyattsville, MD, USA
    J Am Diet Assoc 108:794-802. 2008
    ..Diet has been related to several characteristics of metabolic syndrome (MSDR) and insulin resistance, which carry an increased risk for diabetes and heart disease...
  22. ncbi LDL cholesterol as a strong predictor of coronary heart disease in diabetic individuals with insulin resistance and low LDL: The Strong Heart Study
    B V Howard
    MedStar Research Institute and Washington Hospital Center, Washington, DC 20010, USA
    Arterioscler Thromb Vasc Biol 20:830-5. 2000
    ..These results support recent recommendations for aggressive control of LDL cholesterol in diabetic individuals, with a target level of <100 mg/dL...
  23. ncbi Risk factor clustering in the insulin resistance syndrome and its relationship to cardiovascular disease in postmenopausal white, black, hispanic, and Asian/Pacific Islander women
    Barbara V Howard
    MedStar Research Institute, Washington, DC, USA
    Metabolism 52:362-71. 2003
    ..0434) and strongly in black women (P =.0095). Components of the IR syndrome appear to be associated with CVD in postmenopausal women, although the magnitude of these relationships differed by ethnicity...
  24. ncbi Dietary patterns are linked to cardiovascular risk factors but not to inflammatory markers in Alaska Eskimos
    Sigal Eilat-Adar
    MedStar Research Institute, Hyattsville, MD 20783, USA
    J Nutr 139:2322-8. 2009
    ..Programs are needed to encourage the availability of healthy food choices for those not able to obtain traditional foods...
  25. ncbi Diabetes mellitus and impaired fasting glucose in Alaska Eskimos: the Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) study
    E A Carter
    Department of Epidemiology and Statistics, MedStar Research Institute, 6495 New Hampshire Avenue, Suite 201, Hyattsville, MD 20783, USA
    Diabetologia 49:29-35. 2006
    ..The high prevalence of IFG indicates that diabetes may become increasingly problematic in this population. Abdominal obesity in women may help explain why diabetes prevalence differs according to sex...
  26. ncbi Prevalence of smoking and its relationship with carotid atherosclerosis in Alaskan Eskimos of the Norton Sound region: the GOCADAN study
    David J Kaufman
    Johns Hopkins University, Washington, DC, USA
    Nicotine Tob Res 10:483-91. 2008
    ..The high prevalence of smoking and low rates of cessation in this population demonstrate an urgent need for smoking prevention and cessation programs among Alaskan Eskimos of the Norton Sound region and other Alaska Native groups...
  27. ncbi Diabetes and cardiovascular disease
    B V Howard
    MedStar Research Institute, 108 Irving Street, NW, Annex 5, Washington, DC 20010, USA
    Curr Atheroscler Rep 2:476-81. 2000
    ..LDL cholesterol and albuminuria should be the targets of preventive strategies, and promising new areas such as cytokines, growth factor, and the role of infection should be further explored...
  28. ncbi Effects of isolated post-challenge hyperglycemia on mortality in American Indians: the Strong Heart Study
    Weiquan Lu
    MedStar Research Institute and Washington Hospital Center, Washington, DC 20010, USA
    Ann Epidemiol 13:182-8. 2003
    ..The magnitude of mortality risk associated with IPH is intermediate between diabetes and IFG. Because those with IPH are at high risk for diabetes, American Indians with IPH should be targeted for diabetes prevention...
  29. ncbi Alcohol intake and glycemia in American Indians: the strong heart study
    Weiquan Lu
    MedStar Research Institute and Washington Hospital Center, Washington, DC, USA
    Metabolism 52:129-35. 2003
    ..Thus, alcohol intake does not appear to be a determinant of diabetes risk in this population...
  30. ncbi Effects of glycaemic control on cardiovascular disease in diabetic American Indians: the Strong Heart Study
    W Q Lu
    MedStar Research Institute, Hyattsville, MD, and Washington Hospital Center, Washington, DC, USA
    Diabet Med 21:311-7. 2004
    ..CONCLUSIONS: These findings highlight the importance of risk factors, such as high blood pressure and dyslipidaemia, in increasing CVD risk in those with diabetes...
  31. ncbi Non-HDL cholesterol as a predictor of cardiovascular disease in type 2 diabetes: the strong heart study
    Weiquan Lu
    MedStar Research Institute and Washington Hospital Center, Washington, DC, USA
    Diabetes Care 26:16-23. 2003
    ..CONCLUSIONS: This study suggests that non-HDL cholesterol index may be particularly useful in predicting CVD risk in patients with diabetes...
  32. ncbi Incidence rates and predictors of diabetes in those with prediabetes: the Strong Heart Study
    Hong Wang
    MedStar Health Research Institute, Hyattsville, MD, USA
    Diabetes Metab Res Rev 26:378-85. 2010
    ..In this article, diabetes risk factors and incidence rates in American Indians (AI) with prediabetes are examined...
  33. ncbi Physical activity and diabetes risk in postmenopausal women
    Judith Hsia
    Department of Medicine, George Washington University, Washington, DC, USA
    Am J Prev Med 28:19-25. 2005
    ..To evaluate the hypothesis that physical activity independently predicts type 2 diabetes risk in postmenopausal African-American, Hispanic, Asian, and Caucasian women...
  34. ncbi Accuracy of lipoprotein lipids and apoproteins in predicting coronary heart disease in diabetic American Indians. The Strong Heart Study
    Dongsheng Hu
    From MedStar Research Institute and Washington Hospital Center, Washington, DC 20010, USA
    Ann Epidemiol 12:79-85. 2002
    ..Although the values for all lipoprotein lipids and apoproteins and their ratios were not large enough to definitely predict CHD, they can be used as screening tools for CHD in diabetic American Indians...
  35. ncbi Metabolic syndrome and coronary angiographic disease progression: the Women's Angiographic Vitamin & Estrogen trial
    Judith Hsia
    Department of Medicine, George Washington University, Washington, DC, USA
    Am Heart J 146:439-45. 2003
    ....
  36. ncbi Relationship of high and low ankle brachial index to all-cause and cardiovascular disease mortality: the Strong Heart Study
    Helaine E Resnick
    Department of Epidemiology, MedStar Research Institute, Hyattsville, Md 20873, USA
    Circulation 109:733-9. 2004
    ..The associations of low (<0.90) and high (>1.40) ankle brachial index (ABI) with risk of all-cause and cardiovascular disease (CVD) mortality have not been examined in a population-based setting...
  37. ncbi Decreased GFR estimated by MDRD or Cockcroft-Gault equation predicts incident CVD: the strong heart study
    Nawar M Shara
    Department of Biostatistics, Epidemiology, Outcomes, and Data Management, MedStar Research Institute, Hyattsville, Maryland, USA
    J Nephrol 22:373-80. 2009
    ..The ability of estimated GFR (eGFR) to predict CVD events during 5-10 years of follow-up is assessed using data from the Strong Heart Study (SHS), a large cohort with a high prevalence of diabetes...
  38. ncbi Incidence of lower-extremity amputation in American Indians: the Strong Heart Study
    Helaine E Resnick
    Department of Epidemiology and Statistics, MedStar Research Institute, 6495 New Hampshire Ave, Suite 201, Hyattsville, MD 20783, USA
    Diabetes Care 27:1885-91. 2004
    ..To define incidence and predictors of nontraumatic lower-extremity amputation (LEA) in a diverse cohort of American Indians with diabetes...
  39. ncbi Evaluation of the American Heart Association cardiovascular disease prevention guideline for women
    Judith Hsia
    George Washington University, Washington, DC, USA
    Circ Cardiovasc Qual Outcomes 3:128-34. 2010
    ..We assigned Women's Health Initiative participants to risk categories as described in the guideline and evaluated clinical event rates within and between strata...
  40. ncbi Validation of self-report of rheumatoid arthritis and systemic lupus erythematosus: The Women's Health Initiative
    Brian T Walitt
    Georgetown University, Washington, DC, USA
    J Rheumatol 35:811-8. 2008
    ..Our objective was to determine the most effective and efficient means to validate self-reported rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) in the WHI...
  41. ncbi Cross-sectional associations of resistin, coronary heart disease, and insulin resistance
    Mary Susan Burnett
    Cardiovascular Research Institute, MedStar Research Institute, Washington, DC 20010, USA
    J Clin Endocrinol Metab 91:64-8. 2006
    ..Recently, resistin was found to be present in atherosclerotic lesions in apoE(-/-) mice. Resistin may be associated with inflammation and atherosclerosis in humans; however, the role of resistin in human disease remains controversial...
  42. ncbi Effects of postmenopausal hormone therapy on rheumatoid arthritis: the women's health initiative randomized controlled trials
    Brian Walitt
    Washington Hospital Center, Washington, DC 20010, USA
    Arthritis Rheum 59:302-10. 2008
    ..To study the effects of postmenopausal hormone therapy (PHT) on the incidence and severity of rheumatoid arthritis (RA)...
  43. ncbi Relationship between glycemic control and depression among American Indians in the Strong Heart Study
    DARREN CALHOUN
    MedStar Research Institute, Hyattsville, MD 20783, USA
    J Diabetes Complications 24:217-22. 2010
    ..To examine the relationship between depression and glycemic control in the Strong Heart Study (SHS), a longitudinal study of cardiovascular disease in American Indians...
  44. ncbi Effect of weight change on natural history of pelvic organ prolapse
    Bela I Kudish
    Department of Obstetrics and Gynecology, Washington Hospital Center, Washington, DC, USA
    Obstet Gynecol 113:81-8. 2009
    ..To evaluate the relationship between change in weight and pelvic organ prolapse (POP) progression/regression in women during a 5-year period...
  45. ncbi Relation of lower-extremity amputation to all-cause and cardiovascular disease mortality in American Indians: the Strong Heart Study
    Helaine E Resnick
    Department of Epidemiology and Statistics, MedStar Research Institute, 6495 New Hampshire Ave, Suite 201, Hyattsville, MD 20783
    Diabetes Care 27:1286-93. 2004
    ..To compare risk of all-cause and cardiovascular disease (CVD) mortality in people with a lower-extremity amputation (LEA) attributable to diabetes and people without an LEA...
  46. ncbi Coronary artery calcification in black women and white women
    Charanjit Khurana
    Division of Cardiology, The George Washington University, Washington, DC, USA
    Am Heart J 145:724-9. 2003
    ..Ethnicity was not an independent predictor of coronary calcification...
  47. ncbi Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease in nondiabetic american indians: the Strong Heart Study
    Helaine E Resnick
    MedStar Research Institute, Hyattsville, MD 20783, USA
    Diabetes Care 26:861-7. 2003
    ..Whether IR and MS predict CVD independently of diabetes and other CVD risk factors is not known. This study examines whether IR and/or presence of MS are independently associated with CVD in nondiabetic American Indians (AI)...
  48. ncbi Diabetes and sleep disturbances: findings from the Sleep Heart Health Study
    Helaine E Resnick
    MedStar Research Institute, Hyattsville, Maryland 20783, USA
    Diabetes Care 26:702-9. 2003
    ..To test the hypothesis that diabetes is independently associated with sleep-disordered breathing (SDB), and in particular that diabetes is associated with sleep abnormalities of a central, rather than obstructive, nature...
  49. ncbi Cardiovascular risk associated with the metabolic syndrome
    Robert S Lindsay
    MedStar Research Institute, 110 Irving Street, Washington Hospital Center, Washington, DC 20010, USA
    Curr Diab Rep 4:63-8. 2004
    ....
  50. ncbi Diabetes and cardiovascular disease
    Helaine E Resnick
    MedStar Research Institute, 108 Irving Street NW, Washington, DC 20010, USA
    Annu Rev Med 53:245-67. 2002
    ....
  51. ncbi Utility of a surrogate measure of insulin resistance in American Indians: the Strong Heart Study
    Helaine E Resnick
    MedStar Research Institute, Washington, DC, USA
    Ethn Dis 12:523-9. 2002
    ....
  52. ncbi Dietary fat and diabetes: a consensus view
    Barbara V Howard
    MedStar Research Institute, Hyattsville, Maryland 20783, USA
    Am J Med 113:38S-40S. 2002
    ....
  53. ncbi Dyslipidemia of the metabolic syndrome
    Giacomo Ruotolo
    Penn Medical Laboratory, MedStar Research Institute, 108 Irving Street NW, Washington, DC 20010, USA
    Curr Cardiol Rep 4:494-500. 2002
    ....
  54. ncbi Comparison of estimated glomerular filtration rates and albuminuria in predicting risk of coronary heart disease in a population with high prevalence of diabetes mellitus and renal disease
    Nawar M Shara
    MedStar Health Research Institute, Hyattsville, Maryland, USA
    Am J Cardiol 107:399-405. 2011
    ..In conclusion, this enhanced calculator should be useful in estimating CHD risk in populations with high prevalence of diabetes and renal disease...
  55. ncbi Women's angiographic vitamin and estrogen trial: design and methods
    Judith Hsia
    Department of Medicine, George Washington University, Washington, DC, USA
    Control Clin Trials 23:708-27. 2002
    ..Quantitative coronary angiography was performed at baseline and repeated after projected mean follow-up of 3 years...
  56. ncbi Assessing the impact of different imputation methods on serial measures of renal function: the Strong Heart Study
    N M Shara
    Department of Epidemiology and Statistics, MedStar Research Institute, Hyattsville, Maryland, USA
    Kidney Int 71:701-5. 2007
    ..For both Scr and eGFR, the AV method provided the most favorable results in predicting CVD risk, regardless of the rate of missing data...
  57. ncbi Prevalence and persistence of antibodies to herpes viruses, Chlamydia pneumoniae and Helicobacter pylori in Alaskan Eskimos: the GOCADAN Study
    J Zhu
    MedStar Research Institute, Penn Medical Laboratory, Washington, DC 20010, USA
    Clin Microbiol Infect 12:118-22. 2006
    ..Over 70% of individuals had antibodies to at least three of the five pathogens tested. The study demonstrated the high prevalence and lifelong persistence of multiple antibodies, suggesting chronic infections among Alaskan Eskimos...
  58. ncbi Lipoprotein management in patients with cardiometabolic risk: consensus statement from the American Diabetes Association and the American College of Cardiology Foundation
    John D Brunzell
    Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, and the Northwest Lipid Laboratory, University of Washington, Seattle, Washington, USA
    Diabetes Care 31:811-22. 2008
  59. ncbi Lipoprotein management in patients with cardiometabolic risk: consensus conference report from the American Diabetes Association and the American College of Cardiology Foundation
    John D Brunzell
    Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, Northwest Lipid Laboratory, University of Washington, Seattle, Washington, USA
    J Am Coll Cardiol 51:1512-24. 2008
  60. ncbi Compliance with National Cholesterol Education Program dietary and lifestyle guidelines among older women with self-reported hypercholesterolemia. The Women's Health Initiative
    Judith Hsia
    Department of Medicine, George Washington University, Washington, DC, USA
    Am J Med 113:384-92. 2002
    ..Dietary therapy remains the first line of treatment for patients with high blood cholesterol levels. Among free-living persons, compliance with National Cholesterol Education Program (NCEP) dietary recommendations is uncertain...
  61. ncbi Dietary calcium is associated with body mass index and body fat in American Indians
    Sigal Eilat-Adar
    MedStar Research Institute, Hyattsville, MD 20783, USA
    J Nutr 137:1955-60. 2007
    ..No relation between calcium intake and BMI or PBF was observed in NHANES III participants. Our data may be used to develop nutritional interventions aimed at weight control in culturally appropriate clinical trials...
  62. ncbi Hemoglobin A1c, fasting glucose, and cardiovascular risk in a population with high prevalence of diabetes: the strong heart study
    Hong Wang
    MedStar Health Research Institute, Hyattsville, MD, USA
    Diabetes Care 34:1952-8. 2011
    ..We compared A1C and fasting plasma glucose (FPG) in predicting cardiovascular disease (CVD) in a population with widespread obesity and diabetes...
  63. ncbi Changes in cardiovascular disease risk factors among American Indians. The Strong Heart Study
    Thomas K Welty
    Aberdeen Area Tribal Chairmen's Health Board, Rapid City, SD, USA
    Ann Epidemiol 12:97-106. 2002
    ..CONCLUSIONS: Improvements in management and prevention of hypertension, diabetes, renal disease, and obesity, and programs to further reduce smoking and alcohol abuse, are urgently needed...
  64. ncbi A longitudinal study of risk factors for incident albuminuria in diabetic American Indians: the Strong Heart Study
    Jiaqiong Xu
    Center for American Indian Health Research, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
    Am J Kidney Dis 51:415-24. 2008
    ..There have been no studies that use longitudinal data with more than 2 measurements and methods of longitudinal data analysis to identify risk factors for incident albuminuria over time more effectively...
  65. ncbi Incidence of diabetes in American Indians of three geographic areas: the Strong Heart Study
    Elisa T Lee
    Center for American Indian Health Research, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190, USA
    Diabetes Care 25:49-54. 2002
    ..To estimate incidence rates of diabetes and associated risk factors among participants of the Strong Heart Study...
  66. ncbi Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial
    Jacques E Rossouw
    Division of Women s Health Initiative, National Heart, Lung, and Blood Institute, 6705 Rockledge Dr, One Rockledge Ctr, Suite 300, Bethesda, MD 20817
    JAMA 288:321-33. 2002
    ..Despite decades of accumulated observational evidence, the balance of risks and benefits for hormone use in healthy postmenopausal women remains uncertain...
  67. ncbi Haptoglobin phenotype is an independent risk factor for cardiovascular disease in individuals with diabetes: The Strong Heart Study
    Andrew P Levy
    Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    J Am Coll Cardiol 40:1984-90. 2002
    ..The goal of this study was to determine if the haptoglobin phenotype was predictive of cardiovascular disease (CVD) in diabetic mellitus (DM)...
  68. ncbi Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women: a randomized controlled trial
    David D Waters
    Division of Cardiology, Room 5G1, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA
    JAMA 288:2432-40. 2002
    ..Hormone replacement therapy (HRT) and antioxidant vitamins are widely used for secondary prevention in postmenopausal women with coronary disease, but no clinical trials have demonstrated benefit to support their use...
  69. ncbi Heritability of carotid artery structure and function: the Strong Heart Family Study
    Kari E North
    Department of Epidemiology, University of North Carolina, Chapel Hill, USA
    Arterioscler Thromb Vasc Biol 22:1698-703. 2002
    ..23), and the augmentation index (h2<0.18). CONCLUSIONS: These results suggest that the additive effects of genes explain a moderate proportion of the variability of carotid artery structure and function...
  70. ncbi Albuminuria in recent-onset type 2 diabetes: the Strong Heart Study
    Jay M Sosenko
    University of Miami School of Medicine, Miami, Florida, USA
    Diabetes Care 25:1078-84. 2002
    ..We have used a prospective cohort study to examine this...
  71. ncbi Effects of insulin resistance and insulin secretion on the efficacy of interventions to retard development of type 2 diabetes mellitus: the DA Qing IGT and Diabetes Study
    Guangwei Li
    Department of Endocrinology, China-Japan Friendship Hospital, Yinghua Yeast Street, Caoyang District, Beijing 100029, People's Republic of China
    Diabetes Res Clin Pract 58:193-200. 2002
    ..CONCLUSION: Both IR and beta-cell function were predictors of diabetes in Chinese with IGT. Lifestyle intervention reduced the incidence of DM and these interventions were more effective in those with less IR...
  72. ncbi Effects of estrogen with and without progestin and obesity on symptomatic gastroesophageal reflux
    Zongli Zheng
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Gastroenterology 135:72-81. 2008
    ..An association between female hormones and symptomatic gastroesophageal reflux disease (GERD) and may be modified by obesity is suggested but not proven. Factors affecting GERD progression, however, are largely unknown...
  73. ncbi Does prevalence of the metabolic syndrome in women with coronary artery disease differ by the ATP III and IDF criteria?
    Todd M Brown
    Health Services Research Training Program, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Womens Health (Larchmt) 17:841-7. 2008
    ..Whether the IDF definition identifies a greater prevalence of the metabolic syndrome than the ATP III definition in women with coronary artery disease (CAD) is unknown...
  74. ncbi Validity of diabetes self-reports in the Women's Health Initiative: comparison with medication inventories and fasting glucose measurements
    Karen L Margolis
    HealthPartners Research Foundation, Minneapolis, MN 55440 1524, USA
    Clin Trials 5:240-7. 2008
    ..Therefore, we studied whether self-report of prevalent and incident diabetes in Women's Health Initiative (WHI) participants was concordant with other diagnostic evidence of diabetes...
  75. ncbi Lipoprotein(a) in American Indians is low and not independently associated with cardiovascular disease. The Strong Heart Study
    Wenyu Wang
    Center for American Indian Health Research, College of Public Health, University of Oklahoma, Oklahoma City, OK, USA
    Ann Epidemiol 12:107-14. 2002
    ..Lp(a) concentration is not an independent predictor of CVD among American Indians; it is higher in those who develop CVD because of its positive correlation with LDL, apoB, and FIB...
  76. ncbi A prospective study of the effect of hypertension and baseline blood pressure on cognitive decline and dementia in postmenopausal women: the Women's Health Initiative Memory Study
    Karen C Johnson
    Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, Tennesse 38163, USA
    J Am Geriatr Soc 56:1449-58. 2008
    ..To examine the relationship between baseline hypertension, blood pressure, and the development of cognitive decline in participants in the Women's Health Initiative Memory Study (WHIMS)...
  77. ncbi Adherence to dietary recommendations for saturated fat, fiber, and sodium is low in American Indians and other U.S. adults with diabetes
    Sigal Eilat-Adar
    Zinman College for Physical Education and Sports, Wingate Institute, 42902 Netanya, Israel
    J Nutr 138:1699-704. 2008
    ..S. population of adults with diabetes and shows that for American Indians with diabetes, programs to decrease SFA and increase fiber intakes are warranted...
  78. ncbi The effect of estrogen use on levels of glucose and insulin and the risk of type 2 diabetes in american Indian postmenopausal women : the strong heart study
    Ying Zhang
    Center for American Indian Health Research, University of Oklahoma Health Sciences Center HSC, Oklahoma City, Oklahoma 73190, USA
    Diabetes Care 25:500-4. 2002
    ..To examine the associations between estrogen use and levels of insulin and glucose as well as the effect of estrogen use on the risk of type 2 diabetes...
  79. ncbi Incidence and risk factors for stroke in American Indians: the Strong Heart Study
    Ying Zhang
    Center for American Indian Health Research, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190, USA
    Circulation 118:1577-84. 2008
    ..There are few published data on the incidence of fatal and nonfatal stroke in American Indians. The aims of this observational study were to determine the incidence of stroke and to elucidate stroke risk factors among American Indians...
  80. ncbi Sugar and cardiovascular disease: A statement for healthcare professionals from the Committee on Nutrition of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association
    Barbara V Howard
    Circulation 106:523-7. 2002
  81. ncbi Calcium plus vitamin D supplementation and the risk of incident diabetes in the Women's Health Initiative
    Ian H De Boer
    Division of Nephrology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA
    Diabetes Care 31:701-7. 2008
    ..We examined the effect of calcium plus vitamin D supplementation on the incidence of drug-treated diabetes in postmenopausal women...
  82. ncbi Linkage analysis of factors underlying insulin resistance: Strong Heart Family Study
    Kari E North
    Department of Epidemiology, University of North Carolina, Chapel Hill, Bank of America Center, 137 E Franklin Street, Suite 306, NC 27514, USA
    Obes Res 13:1877-84. 2005
    ..The corroboration of existing QTLs will bring us closer to the identification of the functional genes that predispose to IR...
  83. ncbi Dietary intakes of nutrients thought to modify cardiovascular risk from three groups of American Indians: The Strong Heart Dietary Study, Phase II
    Jamie Stang
    Leadership Education and Training Program in Maternal and Child Health Nutrition, University of Minnesota, Minneapolis, USA
    J Am Diet Assoc 105:1895-903. 2005
    ..Dietary factors play a role in the development of CVD and associated comorbid conditions, yet surprisingly few data exist to describe the dietary intakes and nutritional adequacy of American Indian adults at risk for CVD...
  84. ncbi Association of albuminuria with systolic and diastolic left ventricular dysfunction in type 2 diabetes: the Strong Heart Study
    Jennifer E Liu
    Division of Cardiology, Box 222, New York Presbyterian Hospital Cornell Medical Center, 525 East 68th Street, New York, NY 10021, USA
    J Am Coll Cardiol 41:2022-8. 2003
    ..We sought to compare systolic and diastolic function in American Indians with diabetes mellitus (DM) based on albuminuria status...
  85. ncbi Relation of left ventricular hypertrophy to inflammation and albuminuria in adults with type 2 diabetes: the strong heart study
    Vittorio Palmieri
    Weill Medical College of Cornell University, New York, New York 10021, USA
    Diabetes Care 26:2764-9. 2003
    ..In the presence of microangiopathy, we found that the atherothrombotic risk profile associated with LVH was independent of BMI and possibly reflected the association of LVH with a higher degree of endothelial dysfunction...
  86. ncbi Combined postmenopausal hormone therapy and cardiovascular disease: toward resolving the discrepancy between observational studies and the Women's Health Initiative clinical trial
    Ross L Prentice
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Epidemiol 162:404-14. 2005
    ..These analyses have implications for both the design and the analysis of observational studies...
  87. ncbi Evidence for genetic factors underlying the insulin resistance syndrome in american indians
    Kari E North
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Obes Res 11:1444-8. 2003
    ..These results suggest that heredity explains a substantial proportion of the variability of the factors that underlie the insulin resistance syndrome in American Indians and that these factors are genetically independent...
  88. ncbi Electrocardiographic repolarization complexity and abnormality predict all-cause and cardiovascular mortality in diabetes: the strong heart study
    Peter M Okin
    Department of Medicine, Division of Cardiology, Cornell Medical Center, New York, New York, USA
    Diabetes 53:434-40. 2004
    ..32-3.12) predicted all-cause mortality. Computerized ECG measures of repolarization abnormality and complexity predict CV and all-cause mortality in type 2 diabetes, supporting their use to identify high-risk individuals with diabetes...
  89. ncbi Insulin, physical activity, and caloric intake in postmenopausal women: breast cancer implications
    Rowan T Chlebowski
    Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 90502, USA
    J Clin Oncol 22:4507-13. 2004
    ..However, there are few data on the relative contribution of physical activity, caloric intake, and BMI to fasting insulin levels...
  90. ncbi Combined echocardiographic left ventricular hypertrophy and electrocardiographic ST depression improve prediction of mortality in American Indians: the Strong Heart Study
    Peter M Okin
    Division of Cardiology, Department of Medicine, Cornell Medical Center, 525 East 68th Street, New York, NY 10021, USA
    Hypertension 43:769-74. 2004
    ..These findings support the value of combining Echo-LVH and ECG-STD to improve risk stratification. These findings require verification in other populations...
  91. ncbi Associations of postmenopausal hormone therapy with markers of hemostasis and inflammation and lipid profiles in diabetic and nondiabetic american Indian women: the strong heart study
    Ying Zhang
    Center for American Indian Health Research, University of Oklahoma HSC, Oklahoma City, Oklahoma 73190, USA
    J Womens Health (Larchmt) 13:155-63. 2004
    ..To examine the associations of postmenopausal hormone therapy (PHT) with indicators of hemostasis and inflammation and with lipid profiles in American Indian women and to determine if diabetes modifies these associations...
  92. ncbi Left atrial systolic force and cardiovascular outcome. The Strong Heart Study
    Marcello Chinali
    Department of Medicine, New York Presbyterian Hospital-Weill Medical College of Cornell University, New York, New York 10021, USA
    Am J Hypertens 18:1570-6; discussion 1577. 2005
    ....
  93. ncbi Risk factors for arterial hypertension in adults with initial optimal blood pressure: the Strong Heart Study
    Giovanni de Simone
    Weill Medical College, Cornell University, New York, NY 10021, USA
    Hypertension 47:162-7. 2006
    ..Possible implications of these findings for primary cardiovascular prevention should be tested in prospective studies...
  94. ncbi A longitudinal study of hypertension risk factors and their relation to cardiovascular disease: the Strong Heart Study
    Wenyu Wang
    Center for American Indian Health Research, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA
    Hypertension 47:403-9. 2006
    ..74 times higher risk of developing hypertension/cardiovascular disease than normotensive participants. Age, diabetes, and macro/microalbuminuria were independently significant risk factors of both hypertension and cardiovascular disease...
  95. ncbi The metabolic syndrome in American Indians: the strong heart study
    Marie Russell
    Phoenix Indian Medical Center, Phoenix, AZ, USA
    J Cardiometab Syndr 2:283-7. 2007
    ..Furthermore, MS may carry a risk beyond that of single risk factors. Identifying MS in American Indians and treating the factors that comprise it may reduce risk of both diabetes and cardiovascular disease in this population...
  96. ncbi Fatty acid consumption and metabolic syndrome components: the GOCADAN study
    Sven O E Ebbesson
    Norton Sound Health Corp, Nome, AK, USA
    J Cardiometab Syndr 2:244-9. 2007
    ..Consumption of long-chain omega-3 FAs from marine sources may improve certain MS components, and thus may reduce risk for cardiovascular disease. High consumption of saturated FAs and trans-FAs may have an adverse effect on MS...
  97. ncbi Leukocyte count as a predictor of cardiovascular events and mortality in postmenopausal women: the Women's Health Initiative Observational Study
    Karen L Margolis
    Hennepin County Medical Center, and Berman Center for Outcomes and Clinical Research, 825 S Eighth Street, Minneapolis, MN 55404, USA
    Arch Intern Med 165:500-8. 2005
    ..Our objective was to describe the relation between the baseline white blood cell (WBC) count and future CVD events and mortality in postmenopausal women...
  98. ncbi Insulin sensitivity and insulin secretion determined by homeostasis model assessment and risk of diabetes in a multiethnic cohort of women: the Women's Health Initiative Observational Study
    Yiqing Song
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Diabetes Care 30:1747-52. 2007
    ..However, prospective data regarding its relation to diabetes risk in ethnically diverse populations are limited...
  99. ncbi Aging and the prevalence of cardiovascular disease risk factors in older American Indians: the Strong Heart Study
    Dorothy A Rhoades
    Native Elder Research Center, University of Colorado Health Sciences Center, Denver, CO, USA
    J Am Geriatr Soc 55:87-94. 2007
    ..To describe longitudinal changes in the prevalence of major cardiovascular disease (CVD) risk factors in aging American Indians...
  100. ncbi Prediction of coronary heart disease in a population with high prevalence of diabetes and albuminuria: the Strong Heart Study
    Elisa T Lee
    Center for American Indian Health Research, College of Public Health, University of Oklahoma Health Sciences Center, PO Box 26901, Oklahoma City, OK 73190, USA
    Circulation 113:2897-905. 2006
    ....
  101. ncbi Impact of obesity on cardiac geometry and function in a population of adolescents: the Strong Heart Study
    Marcello Chinali
    Department of Medicine, New York Presbyterian Hospital-Weill Medical College of Cornell University, New York, New York, USA
    J Am Coll Cardiol 47:2267-73. 2006
    ....

Research Grants4

  1. Genetics of Coronary Artery Disease in Alaska Natives (*
    Barbara Howard; Fiscal Year: 2006
    ..GOCADAN will lead the valuable therapeutic and prevention strategies for this and other populations in the United States and the world, where the epidemics of obesity, diabetes, and CVD are increasing rapidly. ..
  2. Cardiovascular Disease in Pima Indians
    Barbara Howard; Fiscal Year: 2007
    ..SHS is valuable because it provides information on how diabetes leads to diseases of the heart and blood vessels that will be useful in many populations who now have high rates of diabetes. ..