Research Topics
| Spencer S LiuSummaryAffiliation: Hospital for Special Surgery Country: USA Publications
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Detail Information
Publications
Association of perioperative use of nonsteroidal anti-inflammatory drugs with postoperative myocardial infarction after total joint replacementSpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery, and Weill College of Medicine of Cornell University, New York, NY 10021, USA
Reg Anesth Pain Med 37:45-50. 2012..Thus, we performed this single-center observational cohort study to determine any association between NSAID use and postoperative myocardial infarction (POMI)...
Incidence of unintentional intraneural injection and postoperative neurological complications with ultrasound-guided interscalene and supraclavicular nerve blocksS S Liu
Hospital for Special Surgery, Weill Cornell Medical College, New York, USA
Anaesthesia 66:168-74. 2011..Intraneural injection occurred in 42 patients (17%; 95% CI 12-22%). No patient suffered from postoperative neurological complications (0%; 95% CI 0-1.6%) at follow-up...
Efficacy of continuous wound catheters delivering local anesthetic for postoperative analgesia: a quantitative and qualitative systematic review of randomized controlled trialsSpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery and the Weill College of Medicine of Cornell University, New York, NY 10021, USA
J Am Coll Surg 203:914-32. 2006
Effect of postoperative analgesia on major postoperative complications: a systematic update of the evidenceSpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery and the Weill College of Medicine of Cornell University, New York, New York 10021, USA
Anesth Analg 104:689-702. 2007..Few individual clinical trials have had sufficient subject numbers to definitively determine the effects of postoperative analgesia on major outcomes...
Trends in mortality, complications, and demographics for primary hip arthroplasty in the United StatesSpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, NY, USA
Int Orthop 33:643-51. 2009..Multiple temporal changes in outcomes and demographics for THA were found. These changes have implications for clinical care and allocation of health resources...
Ultrasound-guided regional anesthesia and analgesia: a qualitative systematic reviewSpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery and Weill Medical College of Cornell University, New York, NY 10021, USA
Reg Anesth Pain Med 34:47-59. 2009..However, ultrasound was not inferior for efficacy, did not increase risk, and offers other potential patient-oriented benefits. All RCTs are rather small, thus completion of large RCTs and case series are encouraged to confirm findings...
A prospective, randomized, controlled trial comparing ultrasound versus nerve stimulator guidance for interscalene block for ambulatory shoulder surgery for postoperative neurological symptomsSpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery, Weill College of Medicine of Cornell University, 535 East 70th St, New York City, NY 10021, USA
Anesth Analg 109:265-71. 2009....
Uncomplicated removal of epidural catheters in 4365 patients with international normalized ratio greater than 1.4 during initiation of warfarin therapySpencer S Liu
Department of Anesthesiology, Cornell University, New York, NY, USA
Reg Anesth Pain Med 36:231-5. 2011..However, these guidelines are based primarily on expert consensus, and there is controversy regarding this recommendation as being "too conservative."..
Evidence basis for ultrasound-guided block characteristics: onset, quality, and durationSpencer S Liu
Departments of Anesthesiology, Hospital for Special Surgery, Weill College of Medicine of Cornell University, New York, NY 10021, USA
Reg Anesth Pain Med 35:S26-35. 2010..This systematic review summarizes existing evidence for superior onset, quality, and duration of block for ultrasound (US) guidance versus other techniques for nerve localization...
Risk of postoperative hypoxemia in ambulatory orthopedic surgery patients with diagnosis of obstructive sleep apnea: a retrospective observational studySpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery, Weill College of Medicine of Cornell University, 535 East 70th Street, New York, NY 10021, USA
Patient Saf Surg 4:9. 2010..Our OSA patients undergoing ambulatory-type orthopedic procedures are monitored overnight in the PACU, thus we reviewed patient records to determine incidence of complications...
Prospective survey of patient-controlled epidural analgesia with bupivacaine and hydromorphone in 3736 postoperative orthopedic patientsSpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery, 535 E 70th St, New York, NY 10021, USA
Reg Anesth Pain Med 35:351-4. 2010..Hydromorphone has potential advantages, yet there are no data to establish its efficacy and safety. Thus, we prospectively monitored our patients receiving PCEA with bupivacaine combined with hydromorphone after orthopedic surgery...
A prospective survey of patient-controlled epidural analgesia with bupivacaine and clonidine after total hip replacement: a pre- and postchange comparison with bupivacaine and hydromorphone in 1,000 patientsSpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery and Weill Cornell Medical College of Cornell University, 535 East 70th Street, New York, NY 10021, USA
Anesth Analg 113:1213-7. 2011..We performed this prospective survey to evaluate analgesia and the side effect profile in total hip replacement patients before and after a systematic change from PCEA with bupivacaine/hydromorphone to bupivacaine/clonidine...
Modeling cost of ultrasound versus nerve stimulator guidance for nerve blocks with sensitivity analysisSpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery, 535 E 70th St, New York, NY 10021, USA
Reg Anesth Pain Med 35:57-63. 2010..Sensitivity analysis allows modeling of different scenarios and determination of the relative importance of each cost input for a given scenario...
The effect of analgesic technique on postoperative patient-reported outcomes including analgesia: a systematic reviewSpencer S Liu
Department of Anesthesiology, The Hospital of Special Surgery, and the Cornell Weill Medical Center, New York, New York, USA
Anesth Analg 105:789-808. 2007..We performed a systematic review to examine the effect of postoperative analgesia on patient-reported outcomes...
A prospective clinical registry of ultrasound-guided regional anesthesia for ambulatory shoulder surgerySpencer S Liu
Department of Anesthesiology, Hospital for Special Surgery, 535 East 70th St, New York, NY 10021, USA
Anesth Analg 111:617-23. 2010..Furthermore, ultrasound-guided supraclavicular block is a novel approach for shoulder anesthesia that may have less risk for neurological symptoms than interscalene block...
Effects of perioperative central neuraxial analgesia on outcome after coronary artery bypass surgery: a meta-analysisSpencer S Liu
Department of Anesthesiology, Virginia Mason Medical Center and the University of Washington, Seattle, Washington 98111, USA
Anesthesiology 101:153-61. 2004..Perioperative central neuraxial analgesia may improve outcome after coronary artery bypass surgery due to attenuation of stress response and superior analgesia...
Comparison of ropivacaine-fentanyl patient-controlled epidural analgesia with morphine intravenous patient-controlled analgesia for perioperative analgesia and recovery after open colon surgeryRobert B Steinberg
Department of Anesthesiology, Baystate Medical Center, Tufts University School of Medicine, Springfield, MA 01199, USA
J Clin Anesth 14:571-7. 2002..002), but time until discharge was similar between groups. CONCLUSIONS: Ropivacaine-fentanyl PCEA provides superior analgesia, reduced opioid requirement, and more rapid recovery after colon surgery...
Demographics, outcomes, and risk factors for adverse events associated with primary and revision total hip arthroplasties in the United StatesStavros G Memtsoudis
Department of Anesthesiology, Hospital for Special Surgery Weill Medical College of Cornell University, New York, NY, USA
Am J Orthop (Belle Mead NJ) 39:E72-7. 2010..Additional studies are warranted to determine causal relationships...
A comparison of regional versus general anesthesia for ambulatory anesthesia: a meta-analysis of randomized controlled trialsSpencer S Liu
Department of Anesthesiology, Virginia Mason Medical Center, Seattle, WA 98111, USA
Anesth Analg 101:1634-42. 2005..Other factors, such as unsuitable discharge criteria and limitations of meta-analysis, may explain this discrepancy...
Cerebral oximetry desaturation during shoulder surgery performed in a sitting position under regional anesthesiaJacques T YaDeau
Department of Anesthesiology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY 10021, USA
Can J Anaesth 58:986-92. 2011..Hypotension in the sitting position may reduce cerebral perfusion and oxygenation. We prospectively determined the incidence of cerebral oximetry (rSO2) desaturation in seated patients undergoing ambulatory shoulder arthroscopy...
The effect of single-injection femoral nerve block versus continuous femoral nerve block after total knee arthroplasty on hospital length of stay and long-term functional recovery within an established clinical pathwayFrancis V Salinas
Department of Anesthesiology, Virginia Mason Medical Center, Seattle, Washington 9810, USA
Anesth Analg 102:1234-9. 2006..The lack of effect provided by increased duration of analgesia (from CFNB) after TKA may now have minimal impact on hospital LOS and long-term functional recovery in the contemporary healthcare environment within the United States...
Performance characteristics and validation of the Opioid-Related Symptom Distress Scale for evaluation of analgesic side effects after orthopedic surgeryJacques T YaDeau
Department of Anesthesiology, Hospital for Special Surgery, Weill Cornell Medical College, 535 East 70th St, New York, NY 10021, USA
Anesth Analg 113:369-77. 2011..Additional validation studies were suggested. We investigated performance characteristics and validity of the ORSDS for postoperative analgesia after 4 types of anesthetic and analgesic regimens...
Effects of Bispectral Index monitoring on ambulatory anesthesia: a meta-analysis of randomized controlled trials and a cost analysisSpencer S Liu
Departments of Anesthesiology, Virginia Mason Medical Center, University of Washington, Seattle, Washington, USA
Anesthesiology 101:311-5. 2004..Use of Bispectral Index (BIS) monitoring for titration of general anesthesia may allow use of less anesthetics, reduction in side effects, and faster patient recovery...
Concurrent expansion of plasma volume and left ventricular end-diastolic volume in patients after rapid infusion of 5% albumin and lactated Ringer's solutionFrancis V Salinas
Department of Anesthesiology, Virginia Mason Medical Center, Seattle, WA, USA
J Clin Anesth 18:510-4. 2006..1% + 0.8%/min vs -0.4% + 0.2%/min; P = 0.006). CONCLUSIONS: Intravenous fluids increased LVEDV to a lesser extent and duration than did plasma volume expansion. Monitoring of LVEDV was a poor guide for fluid administration to maximize CI...
Where in the world is ASRA AcutePOP?Spencer S Liu
Department of Anesthesiology, Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, USA
Reg Anesth Pain Med 34:269-74. 2009..Development of a Web site and applications continues, and a demonstration is planned for the ASRA 2009 meeting...
Anesthesia and analgesia for colon surgerySpencer S Liu
Department of Anesthesiology, Virginia Mason Medical Center, Seattle, WA, USA
Reg Anesth Pain Med 29:52-7. 2004
Prospective comparison of continuous femoral nerve block with nonstimulating catheter placement versus stimulating catheter-guided perineural placement in volunteersFrancis V Salinas
Department of Anesthesiology, Virginia Mason Medical Center, 1100 9th Avenue, B2 AN, Seattle, WA 98101, USA
Reg Anesth Pain Med 29:212-20. 2004..Stimulating catheter-guided perineural placement may potentially increase the success rate and quality of continuous femoral nerve block as compared with a nonstimulating catheter technique. These hypotheses have not been rigorously tested...
Nerve stimulator versus ultrasound guidance for placement of popliteal catheters for foot and ankle surgeryDaniel Maalouf
Department of Anesthesiology, Hospital for Special Surgery, New York, NY 10021, USA
J Clin Anesth 24:44-50. 2012..To determine whether ultrasound guidance improves the quality of continuous popliteal block when compared with a nerve stimulator after major foot and ankle surgery...
Addition of pregabalin to multimodal analgesic therapy following ankle surgery: a randomized double-blind, placebo-controlled trialJacques T YaDeau
From the Department of Anesthesiology Hospital for Special Surgery, Weill Cornell Medical College Department of Anesthesiology, NYU Langone Medical Center, New York, NY Department of Anesthesiology, University of Texas Health Science Center, Houston, TX and Department of Orthopedic Surgery, Hospital for Special Surgery, Weill Cornell Medical College, NewYork, NY
Reg Anesth Pain Med 37:302-7. 2012..Secondary outcomes included measures of opioid and pregabalin adverse effects...
Perioperative pulmonary outcomes in patients with sleep apnea after noncardiac surgeryStavros Memtsoudis
Department of Anesthesiology, Hospital for Special Surgery, Weill Medical College of Cornell University, 535 East 70th St, New York, NY 10021, USA
Anesth Analg 112:113-21. 2011....
Continuous plexus and peripheral nerve blocks for postoperative analgesiaSpencer S Liu
Department of Anesthesiology, Virginia Mason Medical Center, Seattle, Washington 98111, USA
Anesth Analg 96:263-72. 2003
Stroke, regional anesthesia in the sitting position, and hypotension: a review of 4169 ambulatory surgery patientsJacques T YaDeau
Department of Anesthesiology, Weill Cornell Medical Center, New York, NY, USA
Reg Anesth Pain Med 36:430-5. 2011....
Methodological quality of randomized controlled trials of postoperative epidural analgesia: validation of the Epidural Analgesia Trial Checklist as a specific instrument to evaluate methodologySpencer S Liu
Department of Anesthesiology, Hospital of Special Surgery, Cornell Weill Medical Center, New York, NY, USA
Reg Anesth Pain Med 35:549-55. 2010..Current instruments for evaluating the quality of methodology are generic; thus, we also developed a specific assessment tool named Epidural Analgesia Trial Checklist (EATC)...
Hyperbaric spinal levobupivacaine: a comparison to racemic bupivacaine in volunteersElizabeth A Alley
Department of Anesthesiology, Virginia Mason Medical Center, Seattle, Washington 98111, USA
Anesth Analg 94:188-93, table of contents. 2002..IMPLICATIONS: Hyperbaric spinal levobupivacaine has equivalent clinical efficacy to hyperbaric spinal bupivacaine over the 4-12-mg ranges...
Efficacy of postoperative epidural analgesia: a meta-analysisBrian M Block
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
JAMA 290:2455-63. 2003..CONCLUSION: Epidural analgesia, regardless of analgesic agent, location of catheter placement, and type and time of pain assessment, provided better postoperative analgesia compared with parenteral opioids...
Gender and post-dural puncture headacheChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, MD 21287, USA
Anesthesiology 105:613-8. 2006..44-0.67). Although the authors found that nonpregnant female subjects seem to have a higher incidence of post-dural puncture headache than males, the etiology behind these findings is not clear from the current meta-analysis...
Continuous local anesthetic wound infusion to improve postoperative outcome: back to the periphery?Henrik Kehlet
Anesthesiology 107:369-71. 2007
A lovely idea: forming an ASRA Acute Postoperative Pain (AcutePOP) databaseSpencer S Liu
Reg Anesth Pain Med 31:291-3. 2006
Acute post-surgical pain management: a critical appraisal of current practice, December 2-4, 2005James P Rathmell
University of Vermont College of Medicine, Burlington, VT 05403, USA
Reg Anesth Pain Med 31:1-42. 2006..This manuscript details those opinions and presents a critical analysis of the existing evidence supporting new and emerging techniques used to control postsurgical pain...
Does continuous peripheral nerve block provide superior pain control to opioids? A meta-analysisJeffrey M Richman
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland, USA
Anesth Analg 102:248-57. 2006..001). CPNB analgesia, regardless of catheter location, provided superior postoperative analgesia and fewer opioid-related side effects when compared with opioid analgesia...
Efficacy of postoperative patient-controlled and continuous infusion epidural analgesia versus intravenous patient-controlled analgesia with opioids: a meta-analysisChristopher L Wu
Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, Baltimore, Maryland 21287, USA
Anesthesiology 103:1079-88; quiz 1109-10. 2005....
Spinal anaesthesia: local anaesthetics and adjuncts in the ambulatory settingFrancis V Salinas
Department of Anaesthesiology, Virginia Mason Medical Center, 1100 Ninth Avenue B2-AN, Seattle, WA 98111, USA
Best Pract Res Clin Anaesthesiol 16:195-210. 2002..Controversies regarding the possible lower risk of TNS with newer spinal anaesthetic techniques and new discharge criteria are reviewed. The final section provides technical pearls to optimize ambulatory spinal anaesthetic outcomes...
An intensive, structured clinical trial can markedly reduce length of stay after abdominal aortic surgerySpencer S Liu
Anesthesiology 97:1025; author reply 1029-31. 2002
