Research Topics
Species | Peter HauserSummaryCountry: USA Publications
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Publications
A prospective study of the incidence and open-label treatment of interferon-induced major depressive disorder in patients with hepatitis CP Hauser
Portland VA Medical Center, Behavioral Health and Neurosciences Division, NW Hepatitis C Field Based Resource Center Oregon Health and Sciences University, Portland, OR 97201, USA
Mol Psychiatry 7:942-7. 2002..SSRIs, in particular citalopram, are an effective treatment for IFN-induced depression in HCV patients...
Antiviral completion rates and sustained viral response in hepatitis C patients with and without preexisting major depressive disorderPeter Hauser
Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, OR 97202, USA
Psychosomatics 50:500-5. 2009..Despite evidence suggesting that the majority of patients with hepatitis C virus (HCV) have psychiatric and substance use disorders, patients with these comorbidities have historically been excluded from antiviral therapy for HCV...
Antiviral therapy completion and response rates among hepatitis C patients with and without schizophreniaMarilyn Huckans
Department of Psychiatry, Oregon Health and Science University, Portland, Oregon, USA
Schizophr Bull 36:165-72. 2010..Despite disproportionately high rates of hepatitis C (HCV) among patients with severe mental illness, to date, there is scant empirical data available regarding antiviral therapy outcomes within this population...
The influence of antiviral therapy on psychiatric symptoms among patients with hepatitis C and schizophreniaMarilyn Huckans
Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, OR, USA
Antivir Ther 15:111-9. 2010..The aim of this study was to determine whether antiviral therapy is associated with higher rates of psychiatric symptoms in patients with schizophrenia (SCHZ)...
Interferon alpha therapy for hepatitis C: treatment completion and response rates among patients with substance use disordersMarilyn S Huckans
Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, USA
Subst Abuse Treat Prev Policy 2:4. 2007....
Prophylactic antidepressant treatment in patients with hepatitis C on antiviral therapy: a double-blind, placebo-controlled trialBenjamin J Morasco
Behavioral Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR 97239, USA
Psychosomatics 51:401-8. 2010..Approximately one-third of patients undergoing interferon-? (IFN-?) therapy for treatment of the hepatitis C virus (HCV) develop major depression, which decreases functioning and may lead to the reduction or discontinuation of treatment...
Predictors of pain intensity and pain functioning in patients with the hepatitis C virusBenjamin J Morasco
Northwest Hepatitis C Resource Center and Mental Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR 97239, USA
Gen Hosp Psychiatry 32:413-8. 2010..To examine the relationships among biological and psychological variables with pain intensity and pain functioning in patients with the hepatitis C virus (HCV)...
Depression comorbidity and antidepressant use in veterans with chronic hepatitis C: results from a retrospective chart reviewJulie A Nelligan
Northwest Hepatitis C Resource Center, Behavioral Health and Clinical Neurosciences Division, Portland Department of Veterans Affairs VA Medical Center, Oregon Health and Science University, Portland, Oregon 97207, USA
J Clin Psychiatry 69:810-6. 2008..In this study we characterize the prevalence and severity of co-morbid depression, as well as antidepressant and other psychotropic prescribing patterns, in a sample of U.S. veterans with HCV...
Relapse to opioid use after treatment of chronic hepatitis C with pegylated interferon and ribavirinAnnette M Matthews
Portland VA Medical Center, 3710 S.W. U.S. Veteran Hospital Rd, P.O. Box 1035 (V3MHC, Portland, OR 97202, USA
Am J Psychiatry 163:1342-7; quiz 1479. 2006
Management of hepatitis C disease among VA patients with schizophrenia and substance use disordersMarilyn S Huckans
Northwest Hepatitis C Resource Center, Portland Veterans Affairs Medical Center, and Department of Psychiatry at Oregon Health and Science University 97239, USA
Psychiatr Serv 57:403-6. 2006....
The cognitive effects of hepatitis C in the presence and absence of a history of substance use disorderMarilyn Huckans
Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, Oregon 97239, USA
J Int Neuropsychol Soc 15:69-82. 2009..Results indicate that chronic HCV is associated with cognitive impairment in the absence of a history of SUD. The most robust deficits appear to be in verbal learning and reasoning/mental flexibility. (JINS, 2009, 15, 69-82.)...
Pain, substance use disorders and opioid analgesic prescription patterns in veterans with hepatitis CAshlee J Whitehead
Northwest Hepatitis C Resource Center, Portland, OR, USA
J Pain Symptom Manage 36:39-45. 2008..13.4 days, P<0.001). These data demonstrate that pain and SUD diagnoses were common among HCV+ patients, and that opioids were frequently prescribed. Co-occurring SUD was not associated with indicators of prescription opioid misuse...
Psychiatric and substance use disorders comorbidities in veterans with hepatitis C virus and HIV coinfectionBret E Fuller
Mental Health Division, Portland Veterans Affairs Medical Center, Portland, Oregon 97210, USA
Curr Opin Psychiatry 22:401-8. 2009..This review covers timely research relative to comorbid conditions that are common in this population including psychiatric diagnoses, substance use disorders and neurocognitive problems...
Prevalence of liver disease in veterans with bipolar disorder or schizophreniaBret E Fuller
Portland Veterans Affairs Medical Center, Portland, OR 97210, USA
Gen Hosp Psychiatry 33:232-7. 2011..To assess the prevalence of three liver diseases [hepatitis C virus (HCV), nonalcoholic fatty liver disease and alcohol-induced cirrhosis] in patients (veterans) with/without schizophrenia/schizoaffective disorder and bipolar disorder...
Screening for depression in patients with hepatitis C using the Beck Depression Inventory-II: do somatic symptoms compromise validity?Alexander L Patterson
Mental Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR, USA
Gen Hosp Psychiatry 33:354-62. 2011..The objective of the study was to evaluate the validity of the Beck Depression Inventory-II (BDI-II) when used to measure depression in patients with hepatitis C virus (HCV)...
Psychiatric and substance use disorders in individuals with hepatitis C: epidemiology and managementJennifer M Loftis
Department of Psychiatry, Oregon Health and Science University, Portland, Oregon, USA
Drugs 66:155-74. 2006....
Hepatitis C testing and infection rates in bipolar patients with and without comorbid substance use disordersAnnette M Matthews
Northwest Hepatitis C Resource Center, and Behaviorual Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR 97202, USA
Bipolar Disord 10:266-70. 2008..Our hypothesis was that HCV antibody testing rates and HCV prevalence would be higher in the BD, SUD, and DD groups than the control group...
Integrated hepatitis C virus treatment: addressing comorbid substance use disorders and HIV infectionMarilyn S Huckans
Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, OR 97239, USA
AIDS 19:S106-15. 2005..Increased infection rates among patients with SUD also warrant integration of HCV and HIV screening and testing into mental health and addiction programmes...
Addressing tri-morbidity (hepatitis C, psychiatric disorders, and substance use): the importance of routine mental health screening as a component of a comanagement model of careMarian Fireman
Northwest Hepatitis C Resource Center and Behavioral Health and Neurosciences Division, Portland, OR 97239, USA
Clin Infect Dis 40:S286-91. 2005..Comanagement treatment models involving mental health care may expand the pool of patients eligible to receive treatment with IFN, as well as enhance treatment outcomes...
Association of interferon-alpha-induced depression and improved treatment response in patients with hepatitis CJennifer M Loftis
Portland VA Medical Center, Behavioral Health and Clinical Neurosciences Division, OR, USA
Neurosci Lett 365:87-91. 2004..In conclusion, our findings suggest that IFN-alpha-induced MDD may be a predictor of a positive response to IFN-alpha therapy, or an indication of optimal dosing...
Administration of pegylated interferon-alpha-2a or -2b does not induce sickness behavior in Lewis ratsJennifer M Loftis
Behavioral Health and Clinical Neurosciences Division, Portland VA Medical Center, 3710 SW US Veteran s Hospital Road, Portland, OR 97239, USA
Psychoneuroendocrinology 31:1289-94. 2006..Collectively, our data suggest that Lewis rats are likely not a useful model to study IFN-induced depression...
The phenomenology and treatment of interferon-induced depressionJennifer M Loftis
Behavioral Health and Clinical Neurosciences Division, Portland VA Medical Center, Portland, OR, USA
J Affect Disord 82:175-90. 2004..Screening and monitoring, ideally using symptom rating scales for depression, and early antidepressant treatment intervention appear necessary to optimize IFN therapy for the majority of patients...
Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1beta and tumor necrosis factor-alphaJennifer M Loftis
Behavioral Health and Clinical Neurosciences Division, Portland VA Medical Center, Department of Psychiatry, Oregon Health and Science University, Portland, OR 97239, USA
Neurosci Lett 430:264-8. 2008..Future studies should investigate how inflammatory mediators play a role in the expression of specific depressive symptoms in patients with chronic infection. Patients with HCV represent an interesting model to examine this relationship...
Treatment outcomes in depression: comparison of remote treatment through telepsychiatry to in-person treatmentPaul E Ruskin
VA Capitol Network Mental Illness Research Education and Clinical Center, Baltimore, MD, USA
Am J Psychiatry 161:1471-6. 2004....
Appreciation of research information in patients with bipolar disorderSahana Misra
Portland Veterans Affairs Medical Center, Portland, OR, USA
Bipolar Disord 10:635-46. 2008..We compared the abilities of euthymic and manic bipolar patients to appreciate and make voluntary decisions regarding research participation...
Psychiatric management of the hepatitis C patientMuhamad Aly Rifai
Northwest Hepatitis C Resource Center, Portland VA Medical Center, Behavioral Health and Clinical Neurosciences Division, PO Box 1034 P3MHADM, Portland, OR 97239, USA
Curr Treat Options Gastroenterol 9:508-19. 2006..In this review, we discuss the process of pretreatment assessment of patients with HCV and psychiatric illness and specifically address IFN- and RBV-induced depression in patients receiving HCV treatment...
Neuropsychiatric side effects of HCV therapy and their treatment: focus on IFN alpha-induced depressionPeter Hauser
Oregon Health Science University, and Behavioral Health and Clincial Neurosciences Division, Portland VA Medical Center, 97239, USA
Gastroenterol Clin North Am 33:S35-50. 2004....
