Hyungshin Yim

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation
    Hyungshin Yim
    Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Ave, Cambridge, MA 02138, USA
    Mol Cell Biol 29:2609-21. 2009
  2. ncbi Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase
    Hyungshin Yim
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 107:19742-7. 2010
  3. ncbi Regulation of the final stage of mitosis by components of the pre-replicative complex and a polo kinase
    Hyungshin Yim
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA
    Cell Cycle 10:1374-7. 2011

Detail Information

Publications3

  1. ncbi Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation
    Hyungshin Yim
    Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Ave, Cambridge, MA 02138, USA
    Mol Cell Biol 29:2609-21. 2009
    ..Our data suggest that Plk1 is required for cell cycle progression not only in mitosis but also for DNA synthesis, maintenance of DNA integrity, and prevention of cell death...
  2. ncbi Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase
    Hyungshin Yim
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Proc Natl Acad Sci U S A 107:19742-7. 2010
    ..These results suggest that Plk1-mediated phosphorylation of Cdc6 promotes the interaction of Cdc6 and Cdk1, leading to the attenuation of Cdk1 activity, release of separase, and subsequent anaphase progression...
  3. ncbi Regulation of the final stage of mitosis by components of the pre-replicative complex and a polo kinase
    Hyungshin Yim
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA
    Cell Cycle 10:1374-7. 2011
    ..Here we discuss how pre-replicative complex factors are connected with Plk1 and affect mitotic exit...