Research Topics
| Alan D WoolfSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Safety evaluation and adverse events monitoring by poison control centers: a framework for herbs & dietary supplementsAlan D Woolf
Harvard Medical School, and Program in Environmental Medicine, Children's Hospital, Boston, MA 02115, USA
Clin Toxicol (Phila) 44:617-22. 2006
The severity of toxic reactions to ephedra: comparisons to other botanical products and national trends from 1993-2002Alan D Woolf
Division of General Pediatrics, Children s Hospital, Boston, Massachusetts 02115, USA
Clin Toxicol (Phila) 43:347-55. 2005..This study's purpose was to compare toxicity from botanical products containing ephedra to nonephedra products...
Update on the clinical management of childhood lead poisoningAlan D Woolf
Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA
Pediatr Clin North Am 54:271-94, viii. 2007..It includes current thinking on the clinical management and prevention of childhood lead poisoning...
Childhood lead poisoning in 2 families associated with spices used in food preparationAlan D Woolf
Pediatric Environmental Health Subspecialty Unit, Children s Hospital, 300 Longwood Ave, Boston, MA 02115, USA
Pediatrics 116:e314-8. 2005..Families traveling abroad should be aware of the potential health risks associated with the purchase and use of spices that have not been tested for purity...
Infantile lead poisoning from an Asian tongue powder: a case report & subsequent public health inquiryAlan D Woolf
Department of Medicine, Children s Hospital, Boston, Massachusetts 02115, USA
Clin Toxicol (Phila) 46:841-4. 2008..Lead poisoning from novel environmental sources continues to present a challenge to clinicians who treat infants and children...
Use of complementary and alternative therapies in childrenA D Woolf
Division of General Pediatrics, Department of Medicine, Children s Hospital and Harvard University, Boston, Massachusetts, USA
Clin Pharmacol Ther 87:155-7. 2010....
Preserving the United States's poison control systemAlan D Woolf
Department of Medicine, Children s Hospital, Boston 02115, USA
Clin Toxicol (Phila) 49:284-6. 2011..The funding of United States's poison control centers is threatened. The following Commentary argues for support of the current outstanding poison control system by presenting the evidence for its cost-effectiveness...
Lead poisoning from use of bronze drinking vessels during the late Chinese Shang dynasty: an in vitro experimentAlan D Woolf
Department of Medicine, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
Clin Toxicol (Phila) 48:757-61. 2010..The contribution of lead leaching from such vessels into the fermented grain wines drunk by the Chinese nobility in ancient times has not been previously estimated...
Dietary supplements: inpatient policies in US children's hospitalsPaula Gardiner
Osher Institute, Harvard Medical School, Boston, Massachusetts, USA
Pediatrics 121:e775-81. 2008..We undertook this study to describe pediatric hospital policies regarding dietary supplements...
Herbal remedies and children: do they work? Are they harmful?Alan D Woolf
Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA
Pediatrics 112:240-6. 2003..This article reviews principles for the clinician to keep in mind while investigating the literature on herbal medicine and addressing the use of herbal medicines with parents...
Environmental evaluation of a child with developmental disabilityJaved Hussain
Pediatric Environmental Health Center, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
Pediatr Clin North Am 54:47-62, viii. 2007..A detailed environmental history and physical examination may help clarify whether there is a plausible relationship between an environmental toxicant and a child's disability...
Views of pediatric health care providers on the use of herbs and dietary supplements in childrenAlan D Woolf
Division of General Pediatrics, Children's Hospital, Boston, MA 02115, USA
Clin Pediatr (Phila) 44:579-87. 2005..The provision of more postgraduate educational opportunities to learn about herbs and dietary supplements may alleviate some practitioners' concerns about their own competency in discussing HDS with families in their practice...
Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste siteRobert O Wright
Harvard School of Public Health, USA
Neurotoxicology 27:210-6. 2006..No other significant relationships were found. These results suggest the need to study further the neuropsychological correlates of developmental exposure to Mn and As, particularly as a mixture...
Enzyme and receptor antagonists for preventing toxicity from the gamma-hydroxybutyric acid precursor 1,4-butanediol in CD-1 miceLawrence S Quang
Division of Emergency Medicine, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
Ann N Y Acad Sci 965:461-72. 2002..However, pretreatment of CD-1 mice with NCS-382 alone produced prolonged failure of the rotarod test, an unexpected synergistic effect with 1,4-BD and presumably GHB, which has not previously been demonstrated...
Encephalopathy from lead poisoning masquerading as a flu-like syndrome in an autistic childMathew George
Harvard Medical Toxicology Program, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
Pediatr Emerg Care 26:370-3. 2010..43 micromol/L) (reference, <10 microg/dL or 0.483 micromol/L). As this case illustrates, prompt recognition is dependent on the skills and suspicions of an astute clinician, especially in the busy emergency department...
Increased blood lead levels in an adolescent girl from a retained bullet. A case reportSusan T Mahan
Department of Orthopaedic Surgery, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
J Bone Joint Surg Am 88:2726-9. 2006
4-methylpyrazole decreases 1,4-butanediol toxicity by blocking its in vivo biotransformation to gamma-hydroxybutyric acidLawrence S Quang
Division of Emergency Medicine, Children s Hospital Boston Harvard Medical School, Boston, Massachusetts, USA
Ann N Y Acad Sci 1025:528-37. 2004..In this murine model of 1,4-BD overdose, 4-MP conferred antidotal effects by inhibiting alcohol dehydrogenase-mediated biotransformation of 1,4-BD to gamma-hydroxybutyric acid...
Heavy metal and pesticide content in commonly prescribed individual raw Chinese Herbal MedicinesEric S J Harris
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA
Sci Total Environ 409:4297-305. 2011....
Introduction: children's health and the environmentAlan D Woolf
Harvard Medical School, Programin Environmental Medicine, Children's Hospital, Boston, Massachusetts 02115, USA
J Toxicol Clin Toxicol 40:447-8. 2002
Health hazards for children at workAlan D Woolf
Harvard Medical School, Program in Environmental Medicine, Children s Hospital, Boston, Massachusetts 02115, USA
J Toxicol Clin Toxicol 40:477-82. 2002..Solutions to this complex and intractable worldwide problem will also require infrastructure changes in the economic and social incentives to child labor, enlightened public health policies, and community-level advocacy and involvement...
Integration of complementary and alternative medicine in a major pediatric teaching hospital: an initial overviewEllen Silver Highfield
Center for Holistic Pediatric Education and Research, Division of General Pediatrics, Children s Hospital, Boston, MA 02115, USA
J Altern Complement Med 11:373-80. 2005..To describe the establishment of a multidisciplinary team of complementary and alternative medicine (CAM) providers and educators in an urban pediatric hospital and affiliated medical school...
Citrus aurantium used for weight loss by an adolescent with anorexia nervosaSusan Gray
Department of Medicine, Children's Hospital, Boston, Massachusetts 02115, USA
J Adolesc Health 37:414-5. 2005..Its adrenergic agonist properties may have masked bradycardia and hypotension while exacerbating her weight loss...
The ambulatory pediatric association fellowship in pediatric environmental health: a 5-year assessmentPhilip J Landrigan
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
Environ Health Perspect 115:1383-7. 2007..Evidence is mounting that environmental exposures contribute to causation of disease in children. Yet few pediatricians are trained to diagnose, treat, or prevent disease of environmental origin...
Elemental mercury exposure: an evidence-based consensus guideline for out-of-hospital managementE Martin Caravati
American Association of Poison Control Centers, Washington, District of Columbia, USA
Clin Toxicol (Phila) 46:1-21. 2008..11) Do not discard elemental mercury in household trash, plumbing drains, or sewer systems. Consult local authorities for the proper disposal of low-level elemental mercury-contaminated household items and thermometers (Grade D)...
Laboratory diagnosis of 1,4-BD and GHB overdose by routine urine organic acid analysisLawrence S Quang
Clin Toxicol (Phila) 43:321-3. 2005
Valproic acid poisoning: an evidence-based consensus guideline for out-of-hospital managementAnthony S Manoguerra
American Association of Poison Control Centers, Washington, District of Columbia 20016, USA
Clin Toxicol (Phila) 46:661-76. 2008..10) A benzodiazepine can be administered by EMS personnel if convulsions are present and if authorized by EMS medical direction, expressed by written treatment protocol or policy, or if there is direct medical oversight (Grade C)...
2001 Annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance SystemToby L Litovitz
Am J Emerg Med 20:391-452. 2002
Atypical antipsychotic medication poisoning: an evidence-based consensus guideline for out-of-hospital managementDaniel J Cobaugh
American Association of Poison Control Centers, Washington, District of Columbia, USA
Clin Toxicol (Phila) 45:918-42. 2007..12) Depending on the specific circumstances, follow-up calls should be made to determine outcome at appropriate intervals based on the clinical judgment of the poison center staff (Grade D)...
Methylphenidate poisoning: an evidence-based consensus guideline for out-of-hospital managementElizabeth J Scharman
American Association of Poison Control Centers, Washington, District of Columbia 20016, USA
Clin Toxicol (Phila) 45:737-52. 2007....
Camphor Poisoning: an evidence-based practice guideline for out-of-hospital managementAnthony S Manoguerra
American Association of Poison Control Centers, Washington, District of Columbia 20016, USA
Clin Toxicol (Phila) 44:357-70. 2006..It is unlikely that symptoms will progress once the patient is removed from the exposure environment (Grade D)...
Acetaminophen poisoning: an evidence-based consensus guideline for out-of-hospital managementRichard C Dart
American Association of Poison Control Centers, Washington, District of Columbia 20016, USA
Clin Toxicol (Phila) 44:1-18. 2006..However, the effects of other drugs might require referral to an emergency department in accordance with the poison center's normal triage criteria. 2) The use of cimetidine as an antidote is not recommended (Grade A)...
Calcium channel blocker ingestion: an evidence-based consensus guideline for out-of-hospital managementKent R Olson
American Association of Poison Control Centers, 3201 New Mexico Ave, NW, Suite 330, Washington, DC 20016, USA
Clin Toxicol (Phila) 43:797-822. 2005..7) Depending on the specific circumstances, follow-up calls should be made to determine outcome at appropriate intervals based on the clinical judgment of the poison center staff (Grade D)...
Ethylene glycol exposure: an evidence-based consensus guideline for out-of-hospital managementE Martin Caravati
American Association of Poison Control Centers, Washington, DC 20016, USA
Clin Toxicol (Phila) 43:327-45. 2005..This referral should be guided by local poison center procedures and community resources (Grade D). (11) The administration of alcohol, fomepizole, thiamine, or pyridoxine is not recommended in the out-of-hospital setting (Grade D)...
Long-acting anticoagulant rodenticide poisoning: an evidence-based consensus guideline for out-of-hospital managementE Martin Caravati
American Association of Poison Control Centers, Washington, District of Columbia 20016, USA
Clin Toxicol (Phila) 45:1-22. 2007..11) Patients with dermal exposures should be decontaminated by washing the skin with mild soap and water (Grade D). 12) The administration of vitamin K is not recommended prior to evaluation for coagulopathy (Grade D)...
Salicylate poisoning: an evidence-based consensus guideline for out-of-hospital managementPeter A Chyka
American Association of Poison Control Centers, Washington, District of Columbia 20016, USA
Clin Toxicol (Phila) 45:95-131. 2007....
Tricyclic antidepressant poisoning: an evidence-based consensus guideline for out-of-hospital managementAlan D Woolf
American Association of Poison Control Centers, Washington, District of Columbia, USA
Clin Toxicol (Phila) 45:203-33. 2007..12) For TCA-associated convulsions, benzodiazepines are recommended (Grade D). 13) Flumazenil is not recommended for patients with TCA poisoning (Grade D)...
Dextromethorphan poisoning: an evidence-based consensus guideline for out-of-hospital managementPeter A Chyka
American Association of Poison Control Centers, Washington, District of Columbia, USA
Clin Toxicol (Phila) 45:662-77. 2007..11) Carefully ascertain by history whether other drugs, such as acetaminophen, were involved in the incident and assess the risk for toxicity or for a drug interaction...
Home visiting and childhood lead poisoning preventionAlan D Woolf
Pediatrics 117:2328-9; author reply 2329-30. 2006
