Research Topics
Species | Lu WangSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Calcium intake and risk of cardiovascular disease: a review of prospective studies and randomized clinical trialsLu Wang
Division of Preventive Medicine, Department of Medicine, Brigham and Womens Hospital, Boston, MA 02215, USA
Am J Cardiovasc Drugs 12:105-16. 2012..More prospective cohort studies and large-scale randomized trials are needed to further evaluate the risks or benefits of calcium supplementation on CVD endpoints as the primary pre-specified outcome...
Fruit and vegetable intake and the risk of hypertension in middle-aged and older womenLu Wang
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Am J Hypertens 25:180-9. 2012..We therefore assessed the prospective association between baseline intake of fruits and vegetables and the risk of hypertension in a large cohort of middle-aged and older women...
The consumption of lycopene and tomato-based food products is not associated with the risk of type 2 diabetes in womenLu Wang
Division of Aging, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
J Nutr 136:620-5. 2006..Our study found little evidence for an association between dietary intake of lycopene or lycopene-containing foods and the risk of type 2 DM...
Systematic review: Vitamin D and calcium supplementation in prevention of cardiovascular eventsLu Wang
Brigham and Women s Hospital and Harvard School of Public Health, Boston, Massachusetts 02215, USA
Ann Intern Med 152:315-23. 2010..Vitamin D and calcium may affect the cardiovascular system independently and interactively...
Plasma lycopene, other carotenoids, and the risk of type 2 diabetes in womenLu Wang
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Am J Epidemiol 164:576-85. 2006..91 (95% CI: 0.46, 1.81) for beta-cryptoxanthin, and 1.35 (95% CI: 0.68, 2.69) for lutein/zeaxanthin. There was no prospective association between baseline plasma carotenoids and the risk of type 2 diabetes in middle-aged and older women...
Dietary intake of selected flavonols, flavones, and flavonoid-rich foods and risk of cancer in middle-aged and older womenLu Wang
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
Am J Clin Nutr 89:905-12. 2009..Flavonoids may protect against cancer development through several biological mechanisms. However, epidemiologic studies on dietary flavonoids and cancer risk have yielded inconsistent results...
Whole- and refined-grain intakes and the risk of hypertension in womenLu Wang
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
Am J Clin Nutr 86:472-9. 2007..Prospective studies linking whole- and refined-grain intakes with the risk of hypertension, a major cardiovascular disease risk factor, remain limited...
Meat intake and the risk of hypertension in middle-aged and older womenLu Wang
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
J Hypertens 26:215-22. 2008....
Relationship between retinal arteriolar narrowing and myocardial perfusion: multi-ethnic study of atherosclerosisLu Wang
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
Hypertension 51:119-26. 2008..This finding suggests that retinal arteriolar narrowing may serve as a marker of coronary microvascular disease...
Alcohol consumption, weight gain, and risk of becoming overweight in middle-aged and older womenLu Wang
Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
Arch Intern Med 170:453-61. 2010..Alcohol consumption is a source of energy intake that may contribute to body weight gain and development of obesity. However, previous studies of this relationship have been limited, with inconsistent results...
Associations of plasma carotenoids with risk factors and biomarkers related to cardiovascular disease in middle-aged and older womenLu Wang
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
Am J Clin Nutr 88:747-54. 2008..Cardiovascular disease (CVD) risk factors may potentially influence plasma concentrations of carotenoids. However, data on the association of plasma carotenoids with CVD related biomarkers are only limited...
Circulating inflammatory and endothelial markers and risk of hypertension in white and black postmenopausal womenLu Wang
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Clin Chem 57:729-36. 2011..However, epidemiologic studies have yet to compare multiple corresponding biomarkers in relation to risk of hypertension, particularly in multiethnic populations...
Dietary fatty acids and the risk of hypertension in middle-aged and older womenLu Wang
900 Commonwealth Ave East, Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
Hypertension 56:598-604. 2010....
Erythrocyte fatty acid composition is associated with the risk of hypertension in middle-aged and older womenLu Wang
Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA, USA
J Nutr 141:1691-7. 2011..However, after controlling for obesity-related metabolic factors, the associations remained significant only for the PS ratio...
Dietary intake of dairy products, calcium, and vitamin D and the risk of hypertension in middle-aged and older womenLu Wang
Division of Preventive Medicine, Harvard School of Public Health, Boston, Mass, USA harvard edu
Hypertension 51:1073-9. 2008....
Physical activity and weight gain preventionI Min Lee
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
JAMA 303:1173-9. 2010..In 2008, federal guidelines recommended at least 150 minutes per week (7.5 metabolic equivalent [MET] hours per week) of moderate-intensity activity for "substantial health benefits."..
Comparison of interleukin-6 and C-reactive protein for the risk of developing hypertension in womenHoward D Sesso
Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215 1204, USA
Hypertension 49:304-10. 2007..In models simultaneously examining IL-6 and CRP, only CRP remained strongly associated with an increased risk of hypertension...
Tomato-based food products are related to clinically modest improvements in selected coronary biomarkers in womenHoward D Sesso
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
J Nutr 142:326-33. 2012..5 servings/wk of tomato-based food products had clinically modest but significant improvements in TC, the TC:HDL cholesterol ratio, and hemoglobin A1c but not other coronary biomarkers...
Physical activity and the risk of becoming overweight or obese in middle-aged and older womenKathryn A Britton
Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Obesity (Silver Spring) 20:1096-103. 2012..In conclusion, higher amounts of total LTPA should be encouraged to prevent obesity. Among those willing to participate in vigorous LTPA, and for whom such activities are not contraindicated, vigorous LPTA should be encouraged...
Estimating individual-level exposure to airborne polycyclic aromatic hydrocarbons throughout the gestational period based on personal, indoor, and outdoor monitoringHyunok Choi
Columbia Center for Children s Environmental Health, Mailman School of Public Health, Columbia University, New York, New York, USA
Environ Health Perspect 116:1509-18. 2008....
Associations of the beta-fibrinogen Hae III and factor XIII Val34Leu gene variants with venous thrombosisMary Cushman
Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05446, USA
Thromb Res 121:339-45. 2007..The factor XIII Val34Leu (100 G-->T) and beta-fibrinogen Hae III (-455 G-->A) gene variants have been associated with reduced risk of venous thrombosis, but not in all studies...
Protein C, antithrombin, and venous thromboembolism incidence: a prospective population-based studyAaron R Folsom
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
Arterioscler Thromb Vasc Biol 22:1018-22. 2002..Attributable risk estimates suggest that low protein C levels account for approximately 2.5% of venous thromboembolic events in the ARIC population...
Fibrin fragment D-dimer and the risk of future venous thrombosisMary Cushman
Laboratory for Clinical Biochemistry Research and Department of Medicine, University of Vermont, Colchester, VT 05446, USA
Blood 101:1243-8. 2003..D-dimer is strongly and positively related to the occurrence of future venous thrombosis...
Coronary risk factors and myocardial perfusion in asymptomatic adults: the Multi-Ethnic Study of Atherosclerosis (MESA)Lu Wang
Division of Epidemiology, School of Public Health, School of Medicine, University of Minnesota, Minneapolis, Minnesota, USA
J Am Coll Cardiol 47:565-72. 2006..Our study results imply that changes in coronary vascular reactivity, in response to risk factors, may be detected in adults without symptomatic CHD...
Coronary artery calcification and myocardial perfusion in asymptomatic adults: the MESA (Multi-Ethnic Study of Atherosclerosis)Lu Wang
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
J Am Coll Cardiol 48:1018-26. 2006..Myocardial perfusion could be impaired by or manifest the progression to subclinical coronary atherosclerosis in the absence of clinical CHD...
Impacts of passive smoking on learning and memory ability of mouse offsprings and intervention by antioxidantsJie Yang
Chinese Center for Disease Control and Prevention, Beijing 100050, China
Biomed Environ Sci 21:144-9. 2008..To determine the impact of passive smoking and the protective effect of antioxidants such as vitamin E and quercetin on learning and memory ability of mouse offsprings...
Variability of myocardial blood flow measurements by magnetic resonance imaging in the multi-ethnic study of atherosclerosisMichael Jerosch-Herold
Department of Radiology, School of Public Health, University of Minnesota, Minneapolis, MN, USA
Invest Radiol 43:155-61. 2008..The purpose of this study was to assess the longitudinal variability for resting and hyperemic MBFs in the Multi-Ethnic Study of Atherosclerosis...
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinibJames Bean
Human Oncology and Pathogenesis Program, Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Proc Natl Acad Sci U S A 104:20932-7. 2007..Taken together, these data suggest that MET amplification occurs independently of EGFR(T790M) mutations and that MET may be a clinically relevant therapeutic target for some patients with acquired resistance to gefitinib or erlotinib...
A decade's studies on metastasis of hepatocellular carcinomaZhao You Tang
Liver Cancer Institute, Zhongshan Hospital, 136 Yi Xue Yuan Road, 200032, Shanghai, PR China
J Cancer Res Clin Oncol 130:187-96. 2004..The further elucidation of the mechanism underlying HCC metastasis will provide a more solid basis for the prediction and prevention of the metastatic recurrence of HCC...
MDM2 promoter polymorphism SNP309 contributes to tumor susceptibility: evidence from 21 case-control studiesZhibin Hu
Laboratory of Reproductive Medicine, Institute of Toxicology, Cancer Research Center of Nanjing Medical University, Nanjing 210029, China
Cancer Epidemiol Biomarkers Prev 16:2717-23. 2007..Further large studies incorporate quantitative detection of different p53-responsible environmental stresses, p53 mutation status, and also functional genetic variants in p53-MDM2-related genes are warranted...
A mathematical model of the cardiovascular system under exerciseLu Wang
Biomedical System Lab, School of Electrical Engineering and Telecommunications, University of New South Wales, UNSW Sydney, N S W 2052, Australia
Conf Proc IEEE Eng Med Biol Soc 2007:1014-7. 2007..Then the new model can estimate both cardiovascular variables and metabolic demand with its simulation results within the range of SD (Standard Deviation, N=10) of the experimental data...
Octreotide acts as an antitumor angiogenesis compound and suppresses tumor growth in nude mice bearing human hepatocellular carcinoma xenograftsWei Dong Jia
Department of General Surgery, Anhui Provincial Hospital, 4 Lu Jiang Road, 230001 Hefei, P R China
J Cancer Res Clin Oncol 129:327-34. 2003....
Plasma fatty acid composition and incidence of diabetes in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) StudyLu Wang
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
Am J Clin Nutr 78:91-8. 2003..Our findings with the use of this biomarker suggest indirectly that the dietary fat profile, particularly that of saturated fat, may contribute to the etiology of diabetes...
[Study on the relationship between polymorphism of insulin-receptor gene EXON2-2257 and insulin resistance in Chinese people]Lu Wang
Department of Epidemiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing 100005, China
Zhonghua Liu Xing Bing Xue Za Zhi 25:49-53. 2004..To understand the role of insulin-receptor gene in the development of insulin resistance on a population-based study in China...
Risk factors for postoperative complications after liver resectionHui Chuan Sun
Liver Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai 200032, China
Hepatobiliary Pancreat Dis Int 4:370-4. 2005..Liver resection is still a complicated operation with a high risk of postoperative morbidity. This study was undertaken to analyze the risk factors for postoperative complications after liver resection...
[Increases of intracranial pressure and changes of blood flow velocity due to acupressure, needle and laser needle acupuncture?]Gerhard Litscher
Biomedizintechnische Forschung in Anästhesie und Intensivmedizin, Medizinische Universitat Graz, Osterreich
Forsch Komplementarmed Klass Naturheilkd 12:190-5. 2005..Pressure on the acupoints St.7 and SJ.22 can lead to significant, reversible increases in intracranial pressure (ICP) in patients with elevated ICP...
Intensity modulated radiation therapy (IMRT) decreases acute skin toxicity for women receiving radiation for breast cancerGary M Freedman
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Am J Clin Oncol 29:66-70. 2006..Our hypothesis is that measures to decrease dose inhomogeneity within the breast and skin with IMRT will improve acute skin toxicity...
Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferationLei Wei
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, USA
Development 129:1705-14. 2002..These results reveal new biological functions for Rho family proteins as essential determinants of cell proliferation signals at looping and chamber maturation stages in mammalian cardiac development...
[Relationship between polymorphisms of vitamin D receptor gene and familial aggregation of HBsAg carriers]Jing Shan
Institute of Hepatitis Research, Affiliated You an Hospital, Capital University of Medical Sciences, Beijing 100096, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 28:148-53. 2006..To determine whether -Taq I T/C and -Fok I C/T polymorphisms of vitamin D receptor (VDR) gene are associated with the familial aggregation of hepatitis B virus (HBV) infection...
The prognostic significance of preoperative plasma levels of osteopontin in patients with hepatocellular carcinomaHui Zhang
Liver Cancer Institute and Zhongshan Hospital, Institutes of Biomedical Science, Fudan University, 180 Feng Lin Road, Shanghai, 200032, China
J Cancer Res Clin Oncol 132:709-17. 2006..This suggests that the preoperative plasma OPN level can be used as a predictive marker for HCC recurrence and may be helpful to assess the prognosis of patients with HCC after surgery...
P48 is a predictive marker for outcome of postoperative interferon-alpha treatment in patients with hepatitis B virus infection-related hepatocellular carcinomaYong-Bing Qian
Liver Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai, China
Cancer 107:1562-9. 2006..CONCLUSIONS: P48 was useful as a predictive marker of outcome after postoperative IFN-alpha treatment in patients with HBV-related HCC...
Incidence and prognostic values of lymph node metastasis in operable hepatocellular carcinoma and evaluation of routine complete lymphadenectomyHui Chuan Sun
Live Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai, People s Republic of China
J Surg Oncol 96:37-45. 2007..To study lymph node metastasis (LNM) and prognosis in patients with operable hepatocellular carcinoma (HCC) as well as the value of routine complete lymphadenectomy. Few studies have been reported on LNM in patients with operable HCC...
Oxygen uptake estimation in humans during exercise using a Hammerstein modelSteven W Su
Human Performance Group, Biomedical Systems Lab, School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW 2052, Australia
Ann Biomed Eng 35:1898-906. 2007..Finally, a Hammerstein model was developed, which may be useful for implementing a control system for the regulation of oxygen uptake during treadmill exercises...
Change in pulse transit time and pre-ejection period during head-up tilt-induced progressive central hypovolaemiaGregory S H Chan
Biomedical Systems Laboratory, School of Electrical Engineering and Telecommunications, University of New South Wales, Sydney, NSW 2052, Australia
J Clin Monit Comput 21:283-93. 2007....
Positive serum hepatitis B e antigen is associated with higher risk of early recurrence and poorer survival in patients after curative resection of hepatitis B-related hepatocellular carcinomaHui Chuan Sun
Liver Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai 200032, China
J Hepatol 47:684-90. 2007..To study the impact of hepatitis B e antigen on tumor recurrence and patients' survival after curative resection of hepatocellular carcinoma...
[Analysis on possibilities of multi-spectral data for quantitative retrieving soil nutrition element contents]Lu Wang
Department of Earth Sciences, Nanjing University, Nanjing 210093, China
Huan Jing Ke Xue 28:1822-8. 2007....
Estimation of oxygen consumption for moderate exercises by using a Hammerstein modelSteven W Su
Human Performance Group, New South Wales Univ, Sydney, NSW, Australia
Conf Proc IEEE Eng Med Biol Soc 1:3427-30. 2006..Finally, a Hammerstein is achieved, which is useful for the control system design of oxygen uptake regulation during treadmill exercises...
Modelling and control for heart rate regulation during treadmill exerciseSteven W Su
Biomed Syst Lab, New South Wales Univ, Sydney, NSW, Australia
Conf Proc IEEE Eng Med Biol Soc 1:4299-302. 2006..Both conventional proportional-integral-derivative (PID) control and the proposed approaches have been employed for the controller design. The proposed algorithm achieves much better heart rate tracking performance...
High-throughput genotyping of single nucleotide polymorphisms using new biplex invader technologyMichael Olivier
Stanford Human Genome Center, Stanford University School of Medicine, 975 California Avenue, Palo Alto, CA 94305, USA
Nucleic Acids Res 30:e53. 2002..The biplex invader assay with its automated set-up and analysis offers a new efficient high-throughput genotyping platform that is suitable for association studies in large study cohorts...
