Research Topics
Genomes and GenesSpecies | Stuart J SchnittSummaryAffiliation: Harvard University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Breast cancer prognostic classification in the molecular era: the role of histological gradeEmad A Rakha
Department of Histopathology, Nottingham City Hospital NHS Trust, Nottingham University, Nottingham, UK
Breast Cancer Res 12:207. 2010....- Declining recurrence among ductal carcinoma in situ patients treated with breast-conserving surgery in the community settingLaurel A Habel
Division of Research, Kaiser Permanente, Northern California, 2000 Broadway, Oakland, CA 94612, USA
Breast Cancer Res 11:R85. 2009..The aims of this study were to examine the use and impact of these therapies on risk of recurrence among ductal carcinoma in situ patients diagnosed and treated in the community setting... - Benign breast disease and breast cancer risk: morphology and beyondStuart J Schnitt
Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
Am J Surg Pathol 27:836-41. 2003..Additional information derived from clinicopathologic follow-up studies, epidemiologic studies, and molecular and genetic studies will provide new insights into benign breast disease and breast cancer risk... - Local outcomes in ductal carcinoma in situ based on patient and tumor characteristicsStuart J Schnitt
Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
J Natl Cancer Inst Monogr 2010:158-61. 2010.... - Classification and prognosis of invasive breast cancer: from morphology to molecular taxonomyStuart J Schnitt
Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Mod Pathol 23:S60-4. 2010.... - Clinging carcinoma: an American perspectiveStuart J Schnitt
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
Semin Diagn Pathol 27:31-6. 2010.... - The diagnosis and management of pre-invasive breast disease: flat epithelial atypia--classification, pathologic features and clinical significanceStuart J Schnitt
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
Breast Cancer Res 5:263-8. 2003..Additional studies are needed to better understand the biological nature and clinical significance of these lesions... - The transition from ductal carcinoma in situ to invasive breast cancer: the other side of the coinStuart J Schnitt
Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
Breast Cancer Res 11:101. 2009..The potential roles of myoepithelial cells and of stromal-epithelial interaction are of particular interest in this regard... - The influence of family history on breast cancer risk in women with biopsy-confirmed benign breast disease: results from the Nurses' Health StudyLaura C Collins
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
Cancer 107:1240-7. 2006..However, the influence of a positive family history (FH) on breast cancer risk among women with biopsy-confirmed BBD is less certain... - Relationship between clinical and pathologic features of ductal carcinoma in situ and patient age: an analysis of 657 patientsLaura C Collins
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue Boston, MA 02215, USA
Am J Surg Pathol 33:1802-8. 2009..Whether these features contribute to the higher local recurrence risk in young women with DCIS treated with the breast-conserving therapy requires further study... - Intake of fiber and nuts during adolescence and incidence of proliferative benign breast diseaseXuefen Su
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, 3rd Floor, Boston, MA 02115, USA
Cancer Causes Control 21:1033-46. 2010..We examined the association between adolescent fiber intake and proliferative BBD, a marker of increased breast cancer risk, in the Nurses' Health Study II... - Expression of IGF1R in normal breast tissue and subsequent risk of breast cancerRulla M Tamimi
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Breast Cancer Res Treat 128:243-50. 2011..Further studies to confirm these findings are necessary... - Lobule type and subsequent breast cancer risk: results from the Nurses' Health StudiesHeather J Baer
Division of General Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
Cancer 115:1404-11. 2009..Lobules in normal breast tissue can be classified based on their degree of development, which may affect their susceptibility to carcinogenesis. However, few epidemiologic studies to date have addressed this... - Columnar cell lesions and subsequent breast cancer risk: a nested case-control studySarah A Aroner
Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
Breast Cancer Res 12:R61. 2010..However, the risk of subsequent breast cancer associated with the presence of CCL in a benign breast biopsy is poorly understood... - Comparison of molecular phenotypes of ductal carcinoma in situ and invasive breast cancerRulla M Tamimi
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA
Breast Cancer Res 10:R67. 2008..The purpose of this study was to compare the prevalence of these distinct molecular subtypes among cases of DCIS and invasive breast cancer... - COX-2 expression predicts worse breast cancer prognosis and does not modify the association with aspirinMichelle D Holmes
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
Breast Cancer Res Treat 130:657-62. 2011..The survival benefit associated with aspirin use did not differ by COX-2 status. COX-2 breast cancer expression is associated with worse prognosis. If aspirin truly impacts breast cancer survival, then it is not solely via COX-2... - High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancerSandro Santagata
Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115
Proc Natl Acad Sci U S A 108:18378-83. 2011..The findings indicate that HSF1 should be evaluated prospectively as an independent prognostic indicator in ER-positive breast cancer. HSF1 may ultimately be a useful therapeutic target in cancer... - Basal cytokeratin and epidermal growth factor receptor expression are not predictive of BRCA1 mutation status in women with triple-negative breast cancersLaura C Collins
Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
Am J Surg Pathol 33:1093-7. 2009..However, whether or not expression of biomarkers characteristic of basal-like breast cancers helps to define a subset of women with triple-negative breast cancers who are likely to harbor BRCA1 mutations is an unresolved issue... - Androgen receptor expression and breast cancer survival in postmenopausal womenRong Hu
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Clin Cancer Res 17:1867-74. 2011..However, the association between tumor AR status and breast cancer survival is uncertain. Hence, we examined the association between AR status and breast cancer survival in the Nurses' Health Study (NHS)... - Magnitude and laterality of breast cancer risk according to histologic type of atypical hyperplasia: results from the Nurses' Health StudyLaura C Collins
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
Cancer 109:180-7. 2007..Atypical hyperplasia (AH) in a benign breast biopsy is associated with an increased breast cancer risk. However, the influence of the histologic type of AH on the magnitude and laterality of breast cancer risk is poorly defined... - Benign breast disease, recent alcohol consumption, and risk of breast cancer: a nested case-control studyRulla M Tamimi
Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Breast Cancer Res 7:R555-62. 2005.... - A prospective study of conservative surgery without radiation therapy in select patients with Stage I breast cancerMay Lim
Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
Int J Radiat Oncol Biol Phys 65:1149-54. 2006..0 cm or more. These results suggest that with the possible exception of elderly women with comorbid conditions, radiation therapy after BCS remains standard treatment... - Outcome of patients with ductal carcinoma in situ untreated after diagnostic biopsy: results from the Nurses' Health StudyLaura C Collins
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
Cancer 103:1778-84. 2005..Studies of patients with ductal carcinoma in situ (DCIS) "treated" by diagnostic biopsy alone have been rare, but provide important opportunities to gain insights into the natural history of these lesions... - Genetic variation and circulating levels of IGF-I and IGFBP-3 in relation to risk of proliferative benign breast diseaseXuefen Su
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Int J Cancer 126:180-90. 2010..These results suggest that genetic variants and circulating levels of IGFBP-3 may play a role in the early stage of breast carcinogenesis... - Adherence to long-term surveillance mammography among women with ductal carcinoma in situ treated with breast-conserving surgeryLarissa Nekhlyudov
Department of Ambulatory Care and Prevention, Harvard Medical School Harvard Pilgrim Health Care, 133 Brookline Ave, 6th Floor, Boston, MA 02215, USA
J Clin Oncol 27:3211-6. 2009..CONCLUSION Surveillance mammography after BCS among insured women with DCIS often did not occur yearly and declined over time after treatment. Patients and providers must remain vigilant about surveillance after BCS... - Ten-Year Risk of Diagnostic Mammograms and Invasive Breast Procedures After Breast-Conserving Surgery for DCISLarissa Nekhlyudov
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 133 Brookline Ave, 6th Floor, Boston, MA 02215
J Natl Cancer Inst 104:614-21. 2012..The frequency of ongoing diagnostic breast evaluations should be included in discussions about treatment... - Prevalence and predictors of loss of wild type BRCA1 in estrogen receptor positive and negative BRCA1-associated breast cancersNadine Tung
Division of Hematology Oncology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Breast Cancer Res 12:R95. 2010.... - Potential role of tissue microarrays for the study of biomarker expression in benign breast disease and normal breast tissueLaura C Collins
Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Appl Immunohistochem Mol Morphol 17:438-41. 2009..Whether or not TMAs may also be a potentially useful platform for assessing biomarkers in benign proliferative breast lesions (BPBL) and normal breast tissue has not been previously studied in detail... - Traditional breast cancer risk factors in relation to molecular subtypes of breast cancerRulla M Tamimi
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
Breast Cancer Res Treat 131:159-67. 2012..Identifying risk factors for less common subtypes such as luminal B, HER2-type and basal-like tumors has important implications for prevention of these more aggressive subtypes... - Estrogen receptor positive breast cancers in BRCA1 mutation carriers: clinical risk factors and pathologic featuresNadine Tung
Division of Hematology Oncology, Beth Israel Deaconess Medical Center, Brookline Avenue, Boston, MA 02215, USA
Breast Cancer Res 12:R12. 2010..We undertook a study to assess the clinical factors that predict for an estrogen receptor positive (ER+) breast cancer in BRCA1 mutation carriers and to characterize the pathologic features of these tumors... - Androgen receptor expression in breast cancer in relation to molecular phenotype: results from the Nurses' Health StudyLaura C Collins
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
Mod Pathol 24:924-31. 2011..Our findings raise the possibility that targeting the androgen receptor pathway may represent a novel therapeutic approach to the management of patients with basal-like cancers... - Clinical outcome of triple negative breast cancer in BRCA1 mutation carriers and noncarriersLarissa J Lee
Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, Massachusetts, USA
Cancer 117:3093-100. 2011..The clinical outcome of women with and without BRCA1 mutations who had TN breast cancer treated with conventional chemotherapy were compared... - Phenotypic alterations in ductal carcinoma in situ-associated myoepithelial cells: biologic and diagnostic implicationsJustin B Hilson
Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Am J Surg Pathol 33:227-32. 2009..This observation should be taken into consideration when selecting MEC markers to help distinguish in situ from invasive breast carcinomas... - Thyroid transcription factor-1 expression in breast carcinomasJudith Robens
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
Am J Surg Pathol 34:1881-5. 2010..We conclude that a small proportion of breast carcinomas show TTF-1 expression. Therefore, the presence of TTF-1 immunoreactivity in a carcinoma cannot by itself be used to exclude the possibility of a breast origin... - Epithelial and stromal cathepsin K and CXCL14 expression in breast tumor progressionCelina G Kleer
Department of Pathology, University of Michigan Cancer Center, Ann Arbor, Michigan, USA
Clin Cancer Res 14:5357-67. 2008..To evaluate the expression of cathepsin K (CTSK) and CXCL14 in stromal and epithelial cells in human breast tumor progression... - DNA repair protein biomarkers associated with time to recurrence in triple-negative breast cancerBrian M Alexander
Dana Farber Brigham and Women s Cancer Center Department of Radiation Oncology, Harvard Medical School, Boston, Massachusetts, USA
Clin Cancer Res 16:5796-804. 2010.... - Phenotypic alterations in myoepithelial cells associated with benign sclerosing lesions of the breastJustin B Hilson
Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
Am J Surg Pathol 34:896-900. 2010..This needs to be taken into consideration when selecting myoepithelial markers to help distinguish benign sclerosing lesions from invasive breast cancer... - Columnar cell lesions of the breastStuart J Schnitt
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115, U.S.A
Adv Anat Pathol 10:113-24. 2003..Recent studies have begun to provide insights into the biological nature and clinical significance of these lesions. In this article, we review the current state of knowledge and propose a simplified scheme for their classification... - Ductal carcinoma in situ with basal-like phenotype: a possible precursor to invasive basal-like breast cancerBradley B Bryan
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
Mod Pathol 19:617-21. 2006.... - Evolution of breast-conserving therapy for localized breast cancerStuart J Schnitt
Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
J Clin Oncol 26:1395-6. 2008 - p63 Immunocytochemistry improves accuracy of diagnosis with fine-needle aspiration of the breastAnthony M Harton
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
Am J Clin Pathol 128:80-5. 2007..When used in conjunction with morphologic examination, p63 immunostaining may be useful to categorize cases problematic by Papanicolaou staining... - Prospective study of wide excision alone for ductal carcinoma in situ of the breastJulia S Wong
Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
J Clin Oncol 24:1031-6. 2006..It has been hypothesized that wide excision alone with margins > or = 1 cm may be adequate treatment for small, grade 1 or 2 ductal carcinoma in situ (DCIS). To test this hypothesis, we conducted a prospective, single-arm trial... - Early life factors and incidence of proliferative benign breast diseaseHeather J Baer
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 14:2889-97. 2005..These results indicate that premenopausal women who were heavier at young ages have lower incidence of proliferative benign breast disease, consistent with previous findings for breast cancer... - Intracystic papillary carcinomas of the breast: a reevaluation using a panel of myoepithelial cell markersLaura C Collins
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
Am J Surg Pathol 30:1002-7. 2006.... - Clinical and pathologic features of ductal carcinoma in situ associated with the presence of flat epithelial atypia: an analysis of 543 patientsLaura C Collins
Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Mod Pathol 20:1149-55. 2007.... - HER2 protein overexpression in estrogen receptor-positive ductal carcinoma in situ of the breast: frequency and implications for tamoxifen therapyLaura C Collins
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
Mod Pathol 18:615-20. 2005..Whether or not HER2 overexpression is associated with a diminished response to tamoxifen in patients with ER-positive DCIS will require investigation in clinical outcome studies... - Genetic and phenotypic characteristics of pleomorphic lobular carcinoma in situ of the breastYunn Yi Chen
Department of Pathology, University of California San Francisco, California 94143, USA
Am J Surg Pathol 33:1683-94. 2009..However, clinical follow-up studies will be required to define the natural history and most appropriate management of these lesions... - Molecular subtypes of breast cancer in relation to paclitaxel response and outcomes in women with metastatic disease: results from CALGB 9342Lyndsay N Harris
Dana Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA
Breast Cancer Res 8:R66. 2006..We analyzed data from CALGB 9342, which tested three doses of paclitaxel in women with advanced disease, to determine whether response and outcomes differed according to HER2, hormone receptor, and p53 status... - Nodal stage classification for breast carcinoma: improving interobserver reproducibility through standardized histologic criteria and image-based trainingRoderick R Turner
Department of Pathology, Saint John s Health Center, 1328 Twenty Second St, Santa Monica, CA 90404, USA
J Clin Oncol 26:258-63. 2008..We sought to determine whether a set of clearly defined histologic criteria could lead to reproducible nodal classification by pathologists... - Alcohol consumption and incidence of benign breast diseaseCelia Byrne
Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School Boston, Massachusetts 02115, USA
Cancer Epidemiol Biomarkers Prev 11:1369-74. 2002..However, greater alcohol consumption earlier in life (ages 18-22 years) was associated with higher proliferative BBD rates, suggesting that timing of exposure may be relevant to disease incidence... - Mammographic breast density and subsequent risk of breast cancer in postmenopausal women according to tumor characteristicsLusine Yaghjyan
Department of Surgery, Division of Public Health Sciences, Washington University in St Louis School of Medicine, St Louis, MO, USA
J Natl Cancer Inst 103:1179-89. 2011..We aimed to determine whether the associations between breast density and subsequent breast cancer varied by tumor characteristics... - Diagnostic agreement in the evaluation of image-guided breast core needle biopsies: results from a randomized clinical trialLaura C Collins
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
Am J Surg Pathol 28:126-31. 2004..89, 95% confidence interval 0.86-0.92). CONCLUSIONS: The level of diagnostic agreement in interpretation of breast CNB is extremely high among pathologists and is comparable to that seen for open surgical biopsy... - Adolescent diet and incidence of proliferative benign breast diseaseHeather J Baer
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
Cancer Epidemiol Biomarkers Prev 12:1159-67. 2003..05). Vegetable fat, vitamin E, and fiber intakes during adolescence were inversely associated with risk of proliferative BBD in this population. Confirmation of these associations may suggest a means for prevention of breast cancer... - Bimodal frequency distribution of estrogen receptor immunohistochemical staining results in breast cancer: an analysis of 825 casesLaura C Collins
Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Am J Clin Pathol 123:16-20. 2005..The overwhelming majority of breast cancers are either completely ER- or unambiguously ER+, and cases with weak ER immunostaining are rare... - Nonmalignant lesions in breast core needle biopsies: to excise or not to excise?Timothy W Jacobs
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
Am J Surg Pathol 26:1095-110. 2002..These include atypical ductal hyperplasia, lobular neoplasia (atypical lobular hyperplasia and lobular carcinoma in situ), papillary lesions, radial scars, fibroepithelial lesions, mucocele-like lesions, and columnar cell lesions... - Estrogen receptor testing of breast cancer in current clinical practice: what's the question?Stuart J Schnitt
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
J Clin Oncol 24:1797-9. 2006 - Outcome after breast-conserving therapy for patients with stage I or II mucinous, medullary, or tubular breast carcinomaSarah A Thurman
Department of Radiation Oncology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Int J Radiat Oncol Biol Phys 59:152-9. 2004..To evaluate the site of first failure of patients with early-stage tubular, mucinous, and medullary breast carcinoma after breast-conserving therapy and compare their results with those of patients with infiltrating ductal carcinoma (IDC)... - Molecular definition of breast tumor heterogeneityMichail Shipitsin
Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
Cancer Cell 11:259-73. 2007..Our data suggest prognostic relevance of CD44+ cells and therapeutic targeting of distinct tumor cell populations... - A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasionMichael Overholtzer
Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
Cell 131:966-79. 2007.... - Images in pathology. Conversation between needle biopsiesStuart J Schnitt
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
Int J Surg Pathol 11:117. 2003 - Association of hormone replacement therapy to estrogen and progesterone receptor status in invasive breast carcinomaWendy Y Chen
Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA
Cancer 101:1490-500. 2004.... - Radial scars of the breast and breast carcinomas have similar alterations in expression of factors involved in vascular stroma formationTimothy W Jacobs
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
Hum Pathol 33:29-38. 2002..These results suggest that a similar disturbance in stromal-epithelial interactions is present in both lesions... - Magnetic resonance imaging of the breast prior to biopsyDavid A Bluemke
Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
JAMA 292:2735-42. 2004..Breast magnetic resonance imaging (MRI) has been shown to have high sensitivity for cancer detection and is increasingly used following mammography to evaluate suspicious breast lesions... - Family history of breast cancer, age and benign breast diseasePenelope M Webb
Department of Social and Preventive Medicine, University of Queensland, Brisbane, Australia
Int J Cancer 100:375-8. 2002..This link adds weight to the belief that BBD with atypia is a precursor or marker lesion for breast cancer... - Interobserver reproducibility in the diagnosis of flat epithelial atypia of the breastFrances P O'Malley
Mount Sinai Hospital and University of Toronto, Toronto, Ontario, Canada
Mod Pathol 19:172-9. 2006..1-97.4%), than for determining its presence (90.4%: 95% CI, 79.9-96.7%). We conclude that the diagnosis of FEA and its distinction from CCLs without atypia is highly reproducible with the use of available diagnostic criteria... - Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancerLyndsay N Harris
Dana Farber Cancer Institute
Clin Cancer Res 13:1198-207. 2007.... - MRI detection of distinct incidental cancer in women with primary breast cancer studied in IBMC 6883Mitchell D Schnall
Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Surg Oncol 92:32-8. 2005..We report on the rate of MRI and mammography detection of foci of distinct incidental cancer in a prospective, multi center trial involving 426 women with confirmed breast cancer at 15 institutions in the US, Canada, and Germany... - Risk factors for local recurrence in patients with invasive breast cancer and negative surgical margins of excision. Where are we and where are we going?Stuart J Schnitt
Am J Clin Pathol 120:485-8. 2003 - (99m)Tc sestamibi breast imaging for the examination of patients with dense and fatty breasts: multicenter studyIraj Khalkhali
Harbor UCLA Medical Center, Torrance, CA, USA
Radiology 222:149-55. 2002..Scintimammography led to similar and significant changes in the posttest likelihood of cancer for both dense and fatty breasts. CONCLUSION: The diagnostic accuracy of scintimammography is not affected by breast density... - Added cancer yield of MRI in screening the contralateral breast of women recently diagnosed with breast cancer: results from the International Breast Magnetic Resonance Consortium (IBMC) trialConstance D Lehman
Department of Radiology, University of Washington, Seattle Cancer Care Alliance, Seattle, Washington 98109, USA
J Surg Oncol 92:9-15; discussion 15-6. 2005..To estimate the added cancer yield of magnetic resonance imaging (MRI) over mammography in the contralateral breast of patients with a recent diagnosis of breast cancer... - Screening women at high risk for breast cancer with mammography and magnetic resonance imagingConstance D Lehman
Department of Radiology, University of Washington, Seattle Cancer Care Alliance, Seattle, Washington 98109 1023, USA
Cancer 103:1898-905. 2005..The authors compared the performance of screening mammography versus magnetic resonance imaging (MRI) in women at genetically high risk for breast cancer... - HER-2 testing and trastuzumab therapy for metastatic breast cancer: a cost-effectiveness analysisElena B Elkin
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Ave, Box 44, New York, NY 10021, USA
J Clin Oncol 22:854-63. 2004..Several tests of varying accuracy and cost are available to identify candidates for trastuzumab. We estimated the cost-effectiveness of alternative HER-2 testing and trastuzumab treatment strategies... - A prospective study of diet and benign breast diseasePenelope M Webb
Queensland Institute of Medical Research, PO Royal Brisbane Hospital, Brisbane, Australia
Cancer Epidemiol Biomarkers Prev 13:1106-13. 2004..They do, however, raise the possibility that high caffeine intake may increase, and use of vitamin supplements may decrease risk of developing AH... - Standard for breast conservation therapy in the management of invasive breast carcinomaMonica Morrow
Northwestern University Medical School, Chicago, IL, USA
CA Cancer J Clin 52:277-300. 2002.... - Standard for the management of ductal carcinoma in situ of the breast (DCIS)Monica Morrow
Northwestern University Medical School, Chicago, IL, USA
CA Cancer J Clin 52:256-76. 2002.... - Diagnostic architectural and dynamic features at breast MR imaging: multicenter studyMitchell D Schnall
Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
Radiology 238:42-53. 2006..To prospectively determine the prevalence and predictive value of three-dimensional (3D) and dynamic breast magnetic resonance (MR) imaging and contrast material kinetic features alone and as part of predictive diagnostic models...