Susan Santangelo

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Paternal age increases the risk for autism in an Iranian population sample
    Roksana Sasanfar
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Mol Autism 1:2. 2010
  2. ncbi A discordant sib-pair linkage analysis of age-related macular degeneration
    Susan L Santangelo
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, USA
    Ophthalmic Genet 26:61-7. 2005
  3. ncbi What is known about autism: genes, brain, and behavior
    Susan L Santangelo
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    Am J Pharmacogenomics 5:71-92. 2005
  4. ncbi A QTL genome scan of the metabolic syndrome and its component traits
    Matthew B McQueen
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    BMC Genet 4:S96. 2003
  5. ncbi A genomewide scan for age-related macular degeneration provides evidence for linkage to several chromosomal regions
    Johanna M Seddon
    Ophthalmology Epidemiology Unit, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Am J Hum Genet 73:780-90. 2003
  6. ncbi Association between microdeletion and microduplication at 16p11.2 and autism
    Lauren A Weiss
    Autism Consortium, Boston, USA
    N Engl J Med 358:667-75. 2008
  7. ncbi A genome-wide linkage and association scan reveals novel loci for autism
    Lauren A Weiss
    Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Nature 461:802-8. 2009
  8. ncbi The genetics of age-related macular degeneration: a review of progress to date
    Stephen Haddad
    Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, 02114, USA
    Surv Ophthalmol 51:316-63. 2006
  9. ncbi Autism and serotonin transporter gene polymorphisms: a systematic review and meta-analysis
    Christine H Huang
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Med Genet B Neuropsychiatr Genet 147:903-13. 2008
  10. ncbi Examination of NRCAM, LRRN3, KIAA0716, and LAMB1 as autism candidate genes
    Holli B Hutcheson
    Center for Human Genetics Research and Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37027, USA
    BMC Med Genet 5:12. 2004

Research Grants

  1. Mapping Genes for Neurocognitive Endophenotypes
    Susan Santangelo; Fiscal Year: 2007

Detail Information

Publications12

  1. ncbi Paternal age increases the risk for autism in an Iranian population sample
    Roksana Sasanfar
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Mol Autism 1:2. 2010
    ..Parental age has been shown to be associated with many disorders, such as schizophrenia, childhood cancer and fetal death. However, results from studies of parental age and autism are inconsistent...
  2. ncbi A discordant sib-pair linkage analysis of age-related macular degeneration
    Susan L Santangelo
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, USA
    Ophthalmic Genet 26:61-7. 2005
    ..Our prior genome scan in 511 affected sib-pairs and other relative pairs identified significant or suggestive linkage signals on chromosomes 1, 2, 3, 6, 8, 10, 12, 16, and 22...
  3. ncbi What is known about autism: genes, brain, and behavior
    Susan L Santangelo
    Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    Am J Pharmacogenomics 5:71-92. 2005
    ..The application of new techniques in autism research is being proposed, including the investigation of abnormal regulation of gene expression, proteomics, and the use of MRI and postmortem analysis of the brain...
  4. ncbi A QTL genome scan of the metabolic syndrome and its component traits
    Matthew B McQueen
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    BMC Genet 4:S96. 2003
    ..We used genotype and phenotype data from the Framingham Heart Study to perform a full-genome scan for quantitative trait loci underlying the metabolic syndrome...
  5. ncbi A genomewide scan for age-related macular degeneration provides evidence for linkage to several chromosomal regions
    Johanna M Seddon
    Ophthalmology Epidemiology Unit, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Am J Hum Genet 73:780-90. 2003
    ..00001. The consistency of many of the other signals across both two-point and multipoint, as well as parametric and nonparametric, analyses indicate several other regions worthy of follow-up...
  6. ncbi Association between microdeletion and microduplication at 16p11.2 and autism
    Lauren A Weiss
    Autism Consortium, Boston, USA
    N Engl J Med 358:667-75. 2008
    ..Autism spectrum disorder is a heritable developmental disorder in which chromosomal abnormalities are thought to play a role...
  7. ncbi A genome-wide linkage and association scan reveals novel loci for autism
    Lauren A Weiss
    Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Nature 461:802-8. 2009
    ..The linkage regions reported here provide targets for rare variation screening whereas the discovery of a single novel association demonstrates the action of common variants...
  8. ncbi The genetics of age-related macular degeneration: a review of progress to date
    Stephen Haddad
    Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, 02114, USA
    Surv Ophthalmol 51:316-63. 2006
    ..Among these, apolipoprotein E (APOE) may be a minor risk locus. Additional genes will likely be identified, and future studies should explore the potential interactions of these genes with other genes as well as environmental factors...
  9. ncbi Autism and serotonin transporter gene polymorphisms: a systematic review and meta-analysis
    Christine H Huang
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Am J Med Genet B Neuropsychiatr Genet 147:903-13. 2008
    ....
  10. ncbi Examination of NRCAM, LRRN3, KIAA0716, and LAMB1 as autism candidate genes
    Holli B Hutcheson
    Center for Human Genetics Research and Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, TN 37027, USA
    BMC Med Genet 5:12. 2004
    ....
  11. ncbi Meta-analysis of genome scans of age-related macular degeneration
    Sheila A Fisher
    Department of Medical and Molecular Genetics, Guy s, King s and St Thomas School of Medicine, King s College London, London SE1 9RT, UK
    Hum Mol Genet 14:2257-64. 2005
    ..Several of the regions identified here showed only weak evidence for linkage in the individual studies. These results will help prioritize regions for future positional and functional candidate gene studies in AMD...
  12. ncbi Intergenerational transmission of tobacco use and dependence: a transdisciplinary perspective
    Edmond D Shenassa
    Brown Medical School, Centers for Behavioral and Preventive Medicine, Providence, RI 02903, USA
    Nicotine Tob Res 5:S55-69. 2003
    ..Research gaps that exist between scientific disciplines are highlighted, and some directions for future research are suggested...

Research Grants5

  1. Mapping Genes for Neurocognitive Endophenotypes
    Susan Santangelo; Fiscal Year: 2007
    ....