Research Topics
Species | Martha PavlakisSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Renal allograft failure predictors after PAK transplantation: results from the New England Collaborative Association of Pancreas ProgramsMartha Pavlakis
Department of Medicine, Division of Nephrology, The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Transplantation 89:1347-53. 2010..The reasons for kidney allograft failure subsequent to pancreas after kidney (PAK) are multifactorial; therefore, we examined these factors to identify a meaningful risk assessment that could assist in patient selection...- Transplantation for type 1 diabetes: whole organ pancreas and islet cellsMartha Pavlakis
Beth Israel Deaconess Medical Center, The Transplant Center, 110 Francis Street, 7th Floor, Boston, MA 02215, USA
Curr Diab Rep 6:473-8. 2006..Beta-cell transplantation continues to evolve, with considerable improvement in results over the past two decades, and is a cost-effective option for select patients with type 1 diabetes... - Mycophenolate mofetil versus sirolimus as an adjunct to calcineurin inhibition after renal transplantationMartha Pavlakis
Medicine at Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Nat Clin Pract Nephrol 2:558-9. 2006 - Pancreas and islet cell transplantation in diabetesMartha Pavlakis
Department of Medicine, Boston, Masachusetts, USA
Curr Opin Endocrinol Diabetes Obes 14:146-50. 2007..The following review of the field of whole organ pancreas and islet cell transplantation for type 1 diabetes mellitus is timely and relevant, since new findings and outcomes in both fields have emerged in the recent past... - New-onset diabetes after transplantationMartha Pavlakis
Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Curr Diab Rep 5:300-4. 2005..Evaluation of patient risk for post-transplant diabetes mellitus and its complications is an important consideration in initial selection and subsequent modification of the immunosuppressive regimen... - Resolved: in minimizing kidney transplant immunosuppression, steroids should go before calcineurin inhibitors: conMartha Pavlakis
Kidney Transplantation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
J Am Soc Nephrol 18:3028-30. 2007 - Live kidney donation: a 36-year-old woman hoping to donate a kidney to her motherMartha Pavlakis
Harvard Medical School, and Beth Israel Deaconess Medical Center, 110 Francis St, Boston, MA 02215, USA
JAMA 305:592-9. 2011..Evaluation and eligibility of live kidney donors and their short- and long-term risks are discussed... - Timing of sirolimus conversion influences recovery of renal function in liver transplant recipientsChristin C Rogers
Department of Pharmacy, Beth Israel Deaconess Medical Center, Boston, MA, USA
Clin Transplant 23:887-96. 2009..The only improvement in the LC group was from conversion to the three-month time point. We conclude that EC to SRL results in a profound improvement in eGFR that begins at three months and is sustained beyond one yr... - Evaluation of native kidney recovery after simultaneous liver-kidney transplantationJean M Francis
Department of Medicine, Boston University Medical Center, Boston, MA, USA
Transplantation 93:530-5. 2012..Identifying predictors of native kidney function recovery after SLK requires an accurate measure of the relative function of all three kidneys in patients with SLK... - On the intraoperative molecular status of renal allografts after vascular reperfusion and clinical outcomesYingyos Avihingsanon
Department of Medicine Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA, USA
J Am Soc Nephrol 16:1542-8. 2005..The transcriptional profiling data provide absolutely essential data to the predictive models, particularly with respect to AR and renal function 6 mo posttransplantation... - Outcomes with conversion from calcineurin inhibitors to sirolimus after renal transplantation in the context of steroid withdrawal or steroid continuationOgo I Egbuna
The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Transplantation 88:684-92. 2009..A number of studies have suggested that conversion from calcineurin inhibitors (CNI) to sirolimus (SRL) can improve graft function in renal transplant patients. None of these studies has converted patients to SRL in the absence of steroids... - Gene expression profiling of the donor kidney at the time of transplantation predicts clinical outcomes 2 years after transplantationGabor Bodonyi-Kovacs
Transplant Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
Hum Immunol 71:451-5. 2010..This post hoc analysis demonstrates that hypothesis-driven, targeted polymerase chain reaction profiling of gene expression in the donor kidney at the time of engraftment can predict 2-year post-transplantation clinical outcomes... - A cross-sectional study of fatigue and sleep quality before and after kidney transplantationJames R Rodrigue
The Transplant Institute, Beth Israel Deaconess Center for Transplant Outcomes and Quality Improvement and Medical Center, Harvard Medical School, Boston, MA 02215, USA
Clin Transplant 25:E13-21. 2011..Fatigue and sleep disturbances are common before and after KTx, and study findings have important implications for their assessment and management... - Practices and barriers in long-term living kidney donor follow-up: a survey of U.S. transplant centersDidier A Mandelbrot
The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Transplantation 88:855-60. 2009.... - Donor postextubation hypotension and age correlate with outcome after donation after cardiac death transplantationKaren J Ho
Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Transplantation 85:1588-94. 2008..We hypothesized that donor postextubation parameters, including duration and severity of hemodynamic instability or hypoxia might be a better predictor of subsequent graft function... - Older living donors provide excellent quality kidneys: a single center experience (older living donors)Scott R Johnson
Division of Transplant Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Clin Transplant 19:600-6. 2005..The role of advanced age live donors remains controversial because of decline in glomerular filtration rate and perceived increased risks of perioperative complications... - Intensive care unit extubation does not preclude extrarenal organ recovery from donors after cardiac deathScott R Johnson
Division of Transplant Surgery, Department of Surgery, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
Transplantation 80:1244-50. 2005..We have sought to increase the utilization of both renal and extrarenal organs from donors after cardiac death (DCD), including DCD donors with ICU extubation... - Gender disparities in the live kidney donor evaluation processKathryn A Tuohy
Transplant Center, Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Transplantation 82:1402-7. 2006..CONCLUSION: Among potential donors approved for donation, females have been significantly more likely to donate than males. The introduction of LN at our center was associated with a decrease in the gender difference in kidney donation... - Social adaptability index predicts kidney transplant outcome: a single-center retrospective analysisJalaj Garg
Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Nephrol Dial Transplant 27:1239-45. 2012..It has been used in the past to define populations at higher risk for inferior clinical outcomes. The objective of this retrospective study was to evaluate the association of the SAI with renal transplant outcome... - Measuring the expectations of kidney donors: initial psychometric properties of the Living Donation Expectancies QuestionnaireJames R Rodrigue
The Transplant Center, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Transplantation 85:1230-4. 2008..0001), Personal Growth (P<0.01), Quid Pro Quo (P<0.0001), and Health Consequences (P<0.0001) expectations. The LDEQ has promise in evaluating donor candidates' expectations... - Spotting the owl: surreptitious cytomegalovirus disease in a renal transplant recipientJoshua L Tarkan
Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Clin Transplant 22:391-5. 2008..Potential pitfalls in making a prompt diagnosis are reviewed. The differential diagnosis of a large oral ulceration in a transplant recipient is broad, but should include CMV infection... - Impact of substance abuse on access to renal transplantationGurprataap S Sandhu
Division of Nephrology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
Transplantation 91:86-93. 2011..The goal of this project was to evaluate the association between recipient's substance abuse and renal transplant access in patients with end-stage renal disease (ESRD)... - A psychological intervention to improve quality of life and reduce psychological distress in adults awaiting kidney transplantationJames R Rodrigue
Center for Transplant Outcomes and Quality Improvement, The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA
Nephrol Dial Transplant 26:709-15. 2011..Effective psychological interventions to improve functioning in these areas are lacking... - Acute crescentic glomerulonephritis in a renal allograft: an unusual complication of fungal infectionOgo Egbuna
Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Am J Kidney Dis 50:468-70. 2007 - Spouse caregivers of kidney transplant patients: quality of life and psychosocial outcomesJames R Rodrigue
The Transplant Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
Prog Transplant 20:335-42; quiz 343. 2010..Little is known about the quality of life, caregiving strain, and psychosocial functioning of these caregivers... - Expression of protective genes in human renal allografts: a regulatory response to injury associated with graft rejectionYingyos Avihingsanon
Division of Immunology, Department of Medicine, Immunobiology Research Center, Harvard Medical School, Boston, MA 02215, USA
Transplantation 73:1079-85. 2002..Little is known of the pattern of expression of such protective genes and the implication thereof in clinical transplantation... - Determinants of hypofiltration during acute renal allograft rejectionAlkesh Jani
Division of Nephrology, Stanford University School of Medicine, Stanford, California, USA
J Am Soc Nephrol 13:773-8. 2002.... - Rupture of an infected liver cyst into the pericardium in a kidney transplant recipient with polycystic kidney diseaseOgo Egbuna
Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Am J Kidney Dis 49:851-3. 2007..We present the case of a renal transplant recipient with an infected dominant polycystic liver cyst that ruptured into the pericardium, leading to tamponade... - BK virus infection after non-renal transplantationMartha Pavlakis
Beth Israel Deaconess Hospital, Boston, Massachusetts, USA
Adv Exp Med Biol 577:185-9. 2006..While much of the subsequent research focuses on patients after renal transplantation, we will review PV impact in patients after bone marrow transplant (BMT) and those with non-renal solid organ transplants... - Activated intrarenal transcription of CTL-effectors and TGF-beta1 in children with focal segmental glomerulosclerosisJuergen Strehlau
Division of Immunology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
Kidney Int 61:90-5. 2002..0001). CONCLUSION: These results support the notion that immunologically mediated events contribute to the progressive renal damage seen in children with FSGS... - Diabetes after transplantation and sirolimus: what's the connection?Martha Pavlakis
J Am Soc Nephrol 19:1255-6. 2008 - Donor kidney exchangesFrancis L Delmonico
New England Organ Bank, Newton, MA, USA
Am J Transplant 4:1628-34. 2004..Thus, this approach also increases access to deceased donor kidneys for the remaining candidates on the list... - Do we know enough to mandate donor evaluation testing?Martha Pavlakis
Am J Transplant 8:466. 2008 - Reproduction and pregnancy in transplant recipients: current practicesDianne B McKay
Scripps Clinic and the Scripps Research Institute, La Jolla, Calif, USA
Prog Transplant 16:127-32. 2006....