Michele Markstein

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster
    Jian Quan Ni
    Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02175, USA
    Nat Methods 5:49-51. 2008
  2. ncbi Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes
    Michele Markstein
    Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nat Genet 40:476-83. 2008
  3. ncbi Immunity regulatory DNAs share common organizational features in Drosophila
    Kate Senger
    Department of Molecular and Cellular Biology, Division of Genetics and Development, University of California, Berkeley, Berkeley, CA 94720, USA
    Mol Cell 13:19-32. 2004
  4. ncbi A regulatory code for neurogenic gene expression in the Drosophila embryo
    Michele Markstein
    Department of Molecular and Cellular Biology, Division of Genetics and Development, 401 Barker Hall, University of California, Berkeley, CA 94720, USA
    Development 131:2387-94. 2004
  5. ncbi Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo
    Michele Markstein
    Department of Molecular and Cell Biology, Division of Genetics and Development, 401 Barker Hall, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 99:763-8. 2002
  6. ncbi Decoding cis-regulatory DNAs in the Drosophila genome
    Michele Markstein
    Department of Molecular Cell Biology, Division of Genetics and Development, 401 Barker Hall, University of California, Berkeley, California 94720, USA
    Curr Opin Genet Dev 12:601-6. 2002
  7. ncbi Whole-genome analysis of dorsal-ventral patterning in the Drosophila embryo
    Angelike Stathopoulos
    Department of Molecular and Cell Biology, Division of Genetics and Development, 401 Barker Hall, University of California, Berkeley, Berkeley, CA 94720, USA
    Cell 111:687-701. 2002

Detail Information

Publications7

  1. ncbi Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster
    Jian Quan Ni
    Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02175, USA
    Nat Methods 5:49-51. 2008
    ..To avoid this problem, we have developed a transgenic RNA interference vector based on the phiC31 site-specific integration method...
  2. ncbi Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes
    Michele Markstein
    Department of Genetics and Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nat Genet 40:476-83. 2008
    ..The generality of our approach makes it adaptable to other model systems to identify and modify loci for optimal transgene expression...
  3. ncbi Immunity regulatory DNAs share common organizational features in Drosophila
    Kate Senger
    Department of Molecular and Cellular Biology, Division of Genetics and Development, University of California, Berkeley, Berkeley, CA 94720, USA
    Mol Cell 13:19-32. 2004
    ..Aspects of this "regulatory code" are essential for the immune response. These results suggest that immunity regulatory DNAs contain constrained organizational features, which may be a general property of eukaryotic enhancers...
  4. ncbi A regulatory code for neurogenic gene expression in the Drosophila embryo
    Michele Markstein
    Department of Molecular and Cellular Biology, Division of Genetics and Development, 401 Barker Hall, University of California, Berkeley, CA 94720, USA
    Development 131:2387-94. 2004
    ..We discuss the prospects for deciphering regulatory codes that link primary DNA sequence information with predicted patterns of gene expression...
  5. ncbi Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo
    Michele Markstein
    Department of Molecular and Cell Biology, Division of Genetics and Development, 401 Barker Hall, University of California, Berkeley, CA 94720, USA
    Proc Natl Acad Sci U S A 99:763-8. 2002
    ..These results suggest that bioinformatics can be used to identify novel target genes and associated regulatory DNAs in a gene network...
  6. ncbi Decoding cis-regulatory DNAs in the Drosophila genome
    Michele Markstein
    Department of Molecular Cell Biology, Division of Genetics and Development, 401 Barker Hall, University of California, Berkeley, California 94720, USA
    Curr Opin Genet Dev 12:601-6. 2002
    ..These methods change the way that cis-DNAs will be analyzed in future studies and offer the promise of unraveling complex gene networks...
  7. ncbi Whole-genome analysis of dorsal-ventral patterning in the Drosophila embryo
    Angelike Stathopoulos
    Department of Molecular and Cell Biology, Division of Genetics and Development, 401 Barker Hall, University of California, Berkeley, Berkeley, CA 94720, USA
    Cell 111:687-701. 2002
    ..The new Dorsal target genes and enhancers represent one of the most extensive gene networks known for any developmental process...