Flavio Mantelli

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Functions of ocular surface mucins in health and disease
    Flavio Mantelli
    Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Curr Opin Allergy Clin Immunol 8:477-83. 2008
  2. ncbi Mucin-type O-glycans in tears of normal subjects and patients with non-Sjögren's dry eye
    Ana Guzman-Aranguez
    Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 50:4581-7. 2009
  3. ncbi Association of cell surface mucins with galectin-3 contributes to the ocular surface epithelial barrier
    PABLO ARGUESO
    Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA
    J Biol Chem 284:23037-45. 2009
  4. ncbi Glycogene expression in conjunctiva of patients with dry eye: downregulation of Notch signaling
    Flavio Mantelli
    Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 50:2666-72. 2009
  5. ncbi Antiadhesive character of mucin O-glycans at the apical surface of corneal epithelial cells
    Mika Sumiyoshi
    Schepens Eye Research Institute and the Department of Ophthalmology, Harvard Medical School, 20 Staniford Street, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 49:197-203. 2008
  6. ncbi Conjunctival mucin deficiency in complete androgen insensitivity syndrome (CAIS)
    Flavio Mantelli
    Interdisciplinary Center for Biomedical Research CIR Laboratory of Ophthalmology, Campus Bio Medico University of Rome, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 245:899-902. 2007
  7. ncbi Itchy-dry eye associated with polycystic ovary syndrome
    Stefano Bonini
    Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University Campus Bio Medico of Rome, Rome, Italy
    Am J Ophthalmol 143:763-771. 2007
  8. ncbi MUC5AC overexpression in tear film of neonates
    Flavio Mantelli
    Interdisciplinary Center for Biomedical Research Laboratory of Ophthalmology, Campus Bio Medico University of Rome, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 245:1377-81. 2007
  9. ncbi Clinical grading of vernal keratoconjunctivitis
    Stefano Bonini
    Department of Ophthalmology, University of Rome Campus Bio Medico, Rome, Italy
    Curr Opin Allergy Clin Immunol 7:436-41. 2007

Collaborators

Detail Information

Publications9

  1. ncbi Functions of ocular surface mucins in health and disease
    Flavio Mantelli
    Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Curr Opin Allergy Clin Immunol 8:477-83. 2008
    ..The purpose of the present review is to describe new concepts on the role of mucins in the protection of corneal and conjunctival epithelia and to identify alterations of mucins in ocular surface diseases...
  2. ncbi Mucin-type O-glycans in tears of normal subjects and patients with non-Sjögren's dry eye
    Ana Guzman-Aranguez
    Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 50:4581-7. 2009
    ..This study was conducted to identify the repertoire of O-glycans in the tear film and the glycosyltransferases associated with their biosynthesis, in normal subjects and patients with non-Sjögren's dry eye...
  3. ncbi Association of cell surface mucins with galectin-3 contributes to the ocular surface epithelial barrier
    PABLO ARGUESO
    Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA
    J Biol Chem 284:23037-45. 2009
    ..Taken together, these results suggest that galectin-3 plays a key role in maintaining mucosal barrier function through carbohydrate-dependent interactions with cell surface mucins...
  4. ncbi Glycogene expression in conjunctiva of patients with dry eye: downregulation of Notch signaling
    Flavio Mantelli
    Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 50:2666-72. 2009
    ..This study aimed to identify the repertoire of genes (glycogenes) involved in biosynthesis of glycoconjugates in conjunctiva of normal subjects and patients with dry eye...
  5. ncbi Antiadhesive character of mucin O-glycans at the apical surface of corneal epithelial cells
    Mika Sumiyoshi
    Schepens Eye Research Institute and the Department of Ophthalmology, Harvard Medical School, 20 Staniford Street, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 49:197-203. 2008
    ..The purpose of this study was to evaluate the contribution of mucin O-glycans to the antiadhesive character of human corneal-limbal epithelial (HCLE) cells...
  6. ncbi Conjunctival mucin deficiency in complete androgen insensitivity syndrome (CAIS)
    Flavio Mantelli
    Interdisciplinary Center for Biomedical Research CIR Laboratory of Ophthalmology, Campus Bio Medico University of Rome, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 245:899-902. 2007
    ..Decreased mucin levels contribute in explaining the tear film instability in CAIS and should be considered an additional cause of dry eye in sex steroid hormone pathology...
  7. ncbi Itchy-dry eye associated with polycystic ovary syndrome
    Stefano Bonini
    Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University Campus Bio Medico of Rome, Rome, Italy
    Am J Ophthalmol 143:763-771. 2007
    ..The authors aimed to define the ocular symptomatology of women with polycystic ovaries and hyperandrogenism...
  8. ncbi MUC5AC overexpression in tear film of neonates
    Flavio Mantelli
    Interdisciplinary Center for Biomedical Research Laboratory of Ophthalmology, Campus Bio Medico University of Rome, Rome, Italy
    Graefes Arch Clin Exp Ophthalmol 245:1377-81. 2007
    ..However, tear-film stability is not only based on the integrity of the lipid layer, but also reflects properties of the underlying mucus layer. Characteristics of the neonatal mucus tear-film layer have not yet been described...
  9. ncbi Clinical grading of vernal keratoconjunctivitis
    Stefano Bonini
    Department of Ophthalmology, University of Rome Campus Bio Medico, Rome, Italy
    Curr Opin Allergy Clin Immunol 7:436-41. 2007
    ..Furthermore, a new grading system of vernal keratoconjunctivitis based on the severity of the disease is proposed. Different treatment options are discussed based on the clinical grade of vernal keratoconjunctivitis...