K D Mandl

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi An unsupervised classification method for inferring original case locations from low-resolution disease maps
    John S Brownstein
    Children s Hospital Informatics Program at the Harvard MIT Division of Health Sciences and Technology, 1 Autumn St, Boston, MA, USA
    Int J Health Geogr 5:56. 2006
  2. ncbi Re-identification of home addresses from spatial locations anonymized by Gaussian skew
    Christopher A Cassa
    Children s Hospital Informatics Program, Children s Hospital Boston, Boston, MA, USA
    Int J Health Geogr 7:45. 2008
  3. ncbi A software tool for creating simulated outbreaks to benchmark surveillance systems
    Christopher A Cassa
    Children s Hospital Informatics Program, Children s Hospital Boston, Boston, MA 02115, USA
    BMC Med Inform Decis Mak 5:22. 2005
  4. ncbi Time series modeling for syndromic surveillance
    Ben Y Reis
    Children s Hospital Informatics Program, Boston, Massachusetts, USA
    BMC Med Inform Decis Mak 3:2. 2003
  5. ncbi Real time spatial cluster detection using interpoint distances among precise patient locations
    Karen L Olson
    Children s Hospital Informatics Program, Children s Hospital Boston, Boston, Massachusetts, USA
    BMC Med Inform Decis Mak 5:19. 2005
  6. ncbi Implementing syndromic surveillance: a practical guide informed by the early experience
    Kenneth D Mandl
    Children s Hospital Informatics Program, Division of Emergency Medicine, Center for Biopreparedness, Children s Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    J Am Med Inform Assoc 11:141-50. 2004
  7. ncbi Integrating medical informatics and health services research: the need for dual training at the clinical health systems and policy levels
    Kenneth D Mandl
    Division of Emergency Medicine, Children s Hospital, Boston, Massachusetts 02115, USA
    J Am Med Inform Assoc 9:127-32. 2002
  8. ncbi Indivo: a personally controlled health record for health information exchange and communication
    Kenneth D Mandl
    Children s Hospital Informatics Program at the Harvard MIT Division of Health Sciences and Technology, Boston, MA, USA
    BMC Med Inform Decis Mak 7:25. 2007
  9. ncbi Syndromic surveillance: the effects of syndrome grouping on model accuracy and outbreak detection
    Ben Y Reis
    Children s Hospital Boston, Boston, MA, USA
    Ann Emerg Med 44:235-41. 2004
  10. ncbi A context-sensitive approach to anonymizing spatial surveillance data: impact on outbreak detection
    Christopher A Cassa
    Children s Hospital Boston, Informatics Program Mandl Group, 1 Autumn Street, 721, Boston, MA 02215 5362 USA
    J Am Med Inform Assoc 13:160-5. 2006

Research Grants

  1. Surveillance and health promotion informatics at work
    Kenneth Mandl; Fiscal Year: 2006
  2. Disease Surveillance in Real Time: Geotemporal Methods
    Kenneth Mandl; Fiscal Year: 2009

Detail Information

Publications75

  1. ncbi An unsupervised classification method for inferring original case locations from low-resolution disease maps
    John S Brownstein
    Children s Hospital Informatics Program at the Harvard MIT Division of Health Sciences and Technology, 1 Autumn St, Boston, MA, USA
    Int J Health Geogr 5:56. 2006
    ..In this report, a method is presented to evaluate whether patient privacy is being breached in the publication of low-resolution disease maps...
  2. ncbi Re-identification of home addresses from spatial locations anonymized by Gaussian skew
    Christopher A Cassa
    Children s Hospital Informatics Program, Children s Hospital Boston, Boston, MA, USA
    Int J Health Geogr 7:45. 2008
    ..If several such versions are available, each can be used to incrementally refine estimates of the original geocoded location...
  3. ncbi A software tool for creating simulated outbreaks to benchmark surveillance systems
    Christopher A Cassa
    Children s Hospital Informatics Program, Children s Hospital Boston, Boston, MA 02115, USA
    BMC Med Inform Decis Mak 5:22. 2005
    ..One approach to benchmarking outbreak detection performance is to create semi-synthetic datasets containing authentic baseline patient data (noise) and injected artificial patient clusters, as signal...
  4. ncbi Time series modeling for syndromic surveillance
    Ben Y Reis
    Children s Hospital Informatics Program, Boston, Massachusetts, USA
    BMC Med Inform Decis Mak 3:2. 2003
    ..Unfortunately, systematic methods for determining the expected number of (ED) visits on a particular day have not yet been well established. We present here a generalized methodology for developing models of expected ED visit rates...
  5. ncbi Real time spatial cluster detection using interpoint distances among precise patient locations
    Karen L Olson
    Children s Hospital Informatics Program, Children s Hospital Boston, Boston, Massachusetts, USA
    BMC Med Inform Decis Mak 5:19. 2005
    ....
  6. ncbi Implementing syndromic surveillance: a practical guide informed by the early experience
    Kenneth D Mandl
    Children s Hospital Informatics Program, Division of Emergency Medicine, Center for Biopreparedness, Children s Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    J Am Med Inform Assoc 11:141-50. 2004
    ....
  7. ncbi Integrating medical informatics and health services research: the need for dual training at the clinical health systems and policy levels
    Kenneth D Mandl
    Division of Emergency Medicine, Children s Hospital, Boston, Massachusetts 02115, USA
    J Am Med Inform Assoc 9:127-32. 2002
    ..This paper provides a brief exploration of 1) existing successful collaborations between health services researchers and informaticians and 2) needs and opportunities for additional joint work in several core research areas...
  8. ncbi Indivo: a personally controlled health record for health information exchange and communication
    Kenneth D Mandl
    Children s Hospital Informatics Program at the Harvard MIT Division of Health Sciences and Technology, Boston, MA, USA
    BMC Med Inform Decis Mak 7:25. 2007
    ..Indivo (formerly PING) is an open source, open standards PCHR with an open application programming interface (API)...
  9. ncbi Syndromic surveillance: the effects of syndrome grouping on model accuracy and outbreak detection
    Ben Y Reis
    Children s Hospital Boston, Boston, MA, USA
    Ann Emerg Med 44:235-41. 2004
    ..We seek to study the effects of different syndrome grouping methods on model accuracy, a key factor in the outbreak-detection performance of syndromic surveillance systems...
  10. ncbi A context-sensitive approach to anonymizing spatial surveillance data: impact on outbreak detection
    Christopher A Cassa
    Children s Hospital Boston, Informatics Program Mandl Group, 1 Autumn Street, 721, Boston, MA 02215 5362 USA
    J Am Med Inform Assoc 13:160-5. 2006
    ..Further, we measure the impact of the skew on detection of spatial clustering as measured by a spatial scanning statistic...
  11. ncbi AEGIS: a robust and scalable real-time public health surveillance system
    Ben Y Reis
    Children s Hospital Informatics Program at the Harvard MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, MA 02115, USA
    J Am Med Inform Assoc 14:581-8. 2007
    ..The report includes a description of the evolution of the design over time in response to the challenges of a regional and national integration environment...
  12. ncbi A susceptible-infected model of early detection of respiratory infection outbreaks on a background of influenza
    Mojdeh Mohtashemi
    MITRE Corporation, Bedford, MA, USA
    J Theor Biol 241:954-63. 2006
    ..The proposed methodology can be applied to a broad range of influenza-like infectious diseases, whether naturally occurring or a result of bioterrorism, and thus can be an integral component of a real-time surveillance system...
  13. ncbi Effect of computed tomography on patient management and costs in children with suspected appendicitis
    B M Pena
    Department of Medicine, Division of Emergency Medicine, Children s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Pediatrics 104:440-6. 1999
    ..We sought to establish effective and efficient strategies for using CT to diagnose and manage children with possible appendicitis...
  14. ncbi A self-scaling, distributed information architecture for public health, research, and clinical care
    Andrew J McMurry
    Children s Hospital Informatics Program at the Harvard MIT Division of Health Sciences and Technology, 300 Longwood Ave, Enders Room 150, Boston, MA 02115, USA
    J Am Med Inform Assoc 14:527-33. 2007
    ..This study sought to define a scalable architecture to support the National Health Information Network (NHIN). This architecture must concurrently support a wide range of public health, research, and clinical care activities...
  15. ncbi Notifying emergency department patients of negative test results: pitfalls of passive communication
    Ron Keren
    Department of Medicine, Children s Hospital, Boston, MA, USA
    Pediatr Emerg Care 19:226-30. 2003
    ..Thus, positive throat culture results are communicated actively and negative results are communicated passively. We sought to determine the effectiveness and safety of such a system...
  16. ncbi The personal internetworked notary and guardian
    A Riva
    Children's Hospital Informatics Program, Division of Endocrinology, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
    Int J Med Inform 62:27-40. 2001
    ..In addition to the basic architecture, we describe tools to populate the patient's record with data from hospital databases and the first testbed applications we are deploying...
  17. ncbi Time to detection of positive cultures in 28- to 90-day-old febrile infants
    R L Kaplan
    Division of Emergency Medicine, Children s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Pediatrics 106:E74. 2000
    ..To determine the time to detection of positive blood, urine, and cerebrospinal fluid (CSF) cultures among febrile 28- to 90-day-old infants...
  18. ncbi Effect of environmental factors on the spatio-temporal patterns of influenza spread
    K M L Charland
    Children s Hospital Informatics Program at the Harvard MIT Division of Health Sciences and Technology, Boston, MA, USA
    Epidemiol Infect 137:1377-87. 2009
    ..027 to -0.0032). Future studies may elucidate biological mechanisms intrinsically linked to solar radiation that contribute to epidemic timing in temperate regions...
  19. ncbi Four strategies for the management of esophageal coins in children
    J V Soprano
    Division of Emergency Medicine, Children s Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA
    Pediatrics 105:e5. 2000
    ..To compare clinical outcomes and costs under 4 strategies for the management of esophageal coins in children...
  20. ncbi Costs and effectiveness of ultrasonography and limited computed tomography for diagnosing appendicitis in children
    B M Pena
    Department of Medicine, Division of Emergency Medicine, Children s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Pediatrics 106:672-6. 2000
    ..A protocol of ultrasonography (US) followed by computed tomography with rectal contrast (CTRC) has been shown to be 94% accurate in the diagnosis of acute appendicitis in children...
  21. ncbi Parent-driven technology for decision support in pediatric emergency care
    Andrew M Fine
    Division of Emergency Medicine, Children s Hospital, Boston, USA
    Jt Comm J Qual Patient Saf 35:307-15. 2009
    ....
  22. ncbi Adverse drug events in the outpatient setting: an 11-year national analysis
    Florence T Bourgeois
    Division of Emergency Medicine, Children s Hospital Boston, MA 02115, USA
    Pharmacoepidemiol Drug Saf 19:901-10. 2010
    ..Population level estimates of outpatient ADEs are limited. Our objective was to provide national estimates and characterizations of outpatient ADEs and determine risk factors associated with these events...
  23. ncbi Outcome reporting among drug trials registered in ClinicalTrials.gov
    Florence T Bourgeois
    Division of Emergency Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Ann Intern Med 153:158-66. 2010
    ..Clinical trial registries are in widespread use to promote transparency around trials and their results...
  24. ncbi The tell-tale heart: population-based surveillance reveals an association of rofecoxib and celecoxib with myocardial infarction
    John S Brownstein
    Children s Hospital Informatics Program at the Harvard MIT Division of Health Sciences and Technology, Boston, Massachusetts, United States of America
    PLoS ONE 2:e840. 2007
    ..COX-2 selective inhibitors are associated with myocardial infarction (MI). We sought to determine whether population health monitoring would have revealed the effect of COX-2 inhibitors on population-level patterns of MI...
  25. ncbi The value of patient self-report for disease surveillance
    Florence T Bourgeois
    Division of Emergency Medicine, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    J Am Med Inform Assoc 14:765-71. 2007
    ..To determine the accuracy of self-reported information from patients and families for use in a disease surveillance system...
  26. ncbi Patients treated at multiple acute health care facilities: quantifying information fragmentation
    Fabienne C Bourgeois
    Division of General Pediatrics, Children s Hospital Boston, Boston, MA 02115, USA
    Arch Intern Med 170:1989-95. 2010
    ..We sought to quantify, at the population level, the burden of fragmentation in the acute care setting across the state of Massachusetts by measuring the rates at which individuals seek care across multiple sites...
  27. ncbi An epidemiological network model for disease outbreak detection
    Ben Y Reis
    Children s Hospital Informatics Program, Harvard MIT Division of Health Sciences and Technology, Children s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Med 4:e210. 2007
    ..As a result, public-health crises and major public events threaten to undermine health-surveillance systems at the very times they are needed most...
  28. ncbi Medicine. Reestablishing the researcher-patient compact
    Isaac S Kohane
    Center for Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA
    Science 316:836-7. 2007
  29. ncbi Linking surveillance to action: incorporation of real-time regional data into a medical decision rule
    Andrew M Fine
    Division of Emergency Medicine, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    J Am Med Inform Assoc 14:206-11. 2007
    ..We incorporate data about recent local trends in meningitis epidemiology into a prediction model differentiating aseptic from bacterial meningitis...
  30. ncbi Early experiences with personal health records
    John D Halamka
    Beth Israel Deaconess Medical Center, Boston, MA, USA
    J Am Med Inform Assoc 15:1-7. 2008
    ..We describe our implementation challenges from 1999 to 2007 and postulate the evolving challenges we will face over the next five years...
  31. ncbi HealthMap: global infectious disease monitoring through automated classification and visualization of Internet media reports
    Clark C Freifeld
    Children s Hospital Informatics Program, Harvard MIT Division of Health Sciences and Technology, 300 Longwood Ave, Boston, MA 02115, USA
    J Am Med Inform Assoc 15:150-7. 2008
    ..Our objective is to address this challenge through the HealthMap.org Web application, an automated system for querying, filtering, integrating and visualizing unstructured reports on disease outbreaks...
  32. ncbi Evaluation of influenza prevention in the workplace using a personally controlled health record: randomized controlled trial
    Florence T Bourgeois
    Division of Emergency Medicine, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    J Med Internet Res 10:e5. 2008
    ..Health promotion programs using PCHRs can potentially be used in a variety of settings and target a large range of health issues...
  33. ncbi Acceptability of a personally controlled health record in a community-based setting: implications for policy and design
    Elissa R Weitzman
    Children s Hospital Informatics Program, One Autumn Street, Room 541, Boston, MA 02215, USA
    J Med Internet Res 11:e14. 2009
    ..Recently launched PCHR platforms include Google Health, Microsoft's HealthVault, and the Dossia platform, based on Indivo...
  34. ncbi Use of unstructured event-based reports for global infectious disease surveillance
    Mikaela Keller
    Harvard Massachusetts Institute of Technology Division of Health Sciences and Technology, Boston, USA
    Emerg Infect Dis 15:689-95. 2009
    ..Such development would further establish event-based monitoring as an invaluable public health resource that provides critical context and an alternative to traditional indicator-based outbreak reporting...
  35. ncbi Pediatric adverse drug events in the outpatient setting: an 11-year national analysis
    Florence T Bourgeois
    Children s Hospital Boston, Division of Emergency Medicine, 300 Longwood Ave, Boston, MA 02115, USA
    Pediatrics 124:e744-50. 2009
    ..We estimated the national incidence of pediatric ADEs requiring medical treatment, described the pediatric population seeking care for ADEs, and characterized the events in terms of patient symptoms and medications implicated...
  36. ncbi Whose personal control? Creating private, personally controlled health records for pediatric and adolescent patients
    Fabienne C Bourgeois
    Division of General Pediatrics, Children s Hospital Boston, Boston, MA 02115, USA
    J Am Med Inform Assoc 15:737-43. 2008
    ..Informed by our own operational involvement in the implementation of the Indivo PCHR, we provide a framework for understanding and addressing the challenges posed by child, adolescent, and family access to PCHRs...
  37. ncbi Longitudinal histories as predictors of future diagnoses of domestic abuse: modelling study
    Ben Y Reis
    Children s Hospital Informatics Program at the Harvard MIT, Division of Health Sciences and Technology, Children s Hospital Boston, Boston, MA, USA
    BMJ 339:b3677. 2009
    ..To determine whether longitudinal data in patients' historical records, commonly available in electronic health record systems, can be used to predict a patient's future risk of receiving a diagnosis of domestic abuse...
  38. ncbi Relative impact of influenza and respiratory syncytial virus in young children
    Florence T Bourgeois
    Division of Emergency Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Pediatrics 124:e1072-80. 2009
    ..We measured the relative impact of influenza and respiratory syncytial virus (RSV) infections in young children in terms of emergency department (ED) visits, clinical care requirements, and overall resource use...
  39. ncbi Surveillance Sans Frontières: Internet-based emerging infectious disease intelligence and the HealthMap project
    John S Brownstein
    Children's Hospital Informatics Program at the Harvard-MIT Division of Health Sciences and Technology, Boston, Massachusetts, United States of America
    PLoS Med 5:e151. 2008
  40. ncbi Pediatric population size is associated with geographic patterns of acute respiratory infections among adults
    John S Brownstein
    Division of Emergency Medicine, Children s Hospital Boston Children s Hospital Informatics Program at the Harvard MIT Division of Health Sciences and Technology, Boston, MA 02215, USA
    Ann Emerg Med 52:63-8. 2008
    ..We measure the association between proportion of children and specific pediatric age groups in a local population with the timing and rate of adult emergency department (ED) utilization for influenza and other acute respiratory infections...
  41. ncbi Use of population health data to refine diagnostic decision-making for pertussis
    Andrew M Fine
    Division of Emergency Medicine, Children s Hospital Boston and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Med Inform Assoc 17:85-90. 2010
    ..To improve identification of pertussis cases by developing a decision model that incorporates recent, local, population-level disease incidence...
  42. ncbi Sharing medical data for health research: the early personal health record experience
    Elissa R Weitzman
    Department of Pediatrics, Harvard Medical School, Boston, United States
    J Med Internet Res 12:e14. 2010
    ..Understanding consumer willingness to share data is critical to advancing this model...
  43. ncbi Integrating spatial epidemiology into a decision model for evaluation of facial palsy in children
    Andrew M Fine
    Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Arch Pediatr Adolesc Med 165:61-7. 2011
    ..To develop a novel diagnostic algorithm for Lyme disease among children with facial palsy by integrating public health surveillance data with traditional clinical predictors...
  44. ncbi The PING personally controlled electronic medical record system: technical architecture
    William W Simons
    Children s Hospital Informatics Program, Enders 1, 300 Longwood Avenue, Boston, MA 02115, USA
    J Am Med Inform Assoc 12:47-54. 2005
    ....
  45. ncbi Use of emergency department chief complaint and diagnostic codes for identifying respiratory illness in a pediatric population
    Allison J Beitel
    Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Pediatr Emerg Care 20:355-60. 2004
    ....
  46. ncbi Prolonged partial thromboplastin times in children with fever and petechiae without bacteremia or sepsis
    Ben M Willwerth
    Division of Pediatric Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Pediatr Emerg Care 19:244-7. 2003
    ..We attempted to validate this finding by comparing the PTTs of children with fever and petechiae who were neither septic nor bacteremic with those of children without fever and petechiae...
  47. ncbi Measuring outbreak-detection performance by using controlled feature set simulations
    Kenneth D Mandl
    Division of Emergency Medicine, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    MMWR Morb Mortal Wkly Rep 53:130-6. 2004
    ..The injected signal is defined by a controlled feature set of variable parameters, including size, shape, and duration...
  48. ncbi Factors affecting automated syndromic surveillance
    Ling Wang
    Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Boston, MA 02118, USA
    Artif Intell Med 34:269-78. 2005
    ..CONCLUSION: This study suggests that the integration of multiple data sources can significantly improve the detection accuracy of syndromic surveillance systems...
  49. ncbi Identifying pediatric age groups for influenza vaccination using a real-time regional surveillance system
    John S Brownstein
    Division of Emergency Medicine, Children s Hospital Boston, Harvard Medical School, Boston, MA 02215, USA
    Am J Epidemiol 162:686-93. 2005
    ..001). Study findings add to a growing body of support for a strategy to vaccinate children older than the currently targeted age of 6-23 months and specifically suggest that there may be value in vaccinating preschool-age children...
  50. ncbi The value of parental report for diagnosis and management of dehydration in the emergency department
    Stephen C Porter
    Division of Emergency Medicine, Children s Hospital, Boston, MA 02115, USA
    Ann Emerg Med 41:196-205. 2003
    ..We also sought to compare the reports of physical signs related to dehydration made by parents and nurses...
  51. ncbi Validation of syndromic surveillance for respiratory infections
    Florence T Bourgeois
    Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Ann Emerg Med 47:265.e1. 2006
    ..This study measures the value of respiratory data currently used in syndromic surveillance systems to detect respiratory infections by comparing it against criterion standard viral testing within a pediatric population...
  52. ncbi Efficacy of an educational Web site for educating physicians about bioterrorism
    Sarita Chung
    Children s Hospital Boston, Department of Pediatrics, Harvard Medical School, Boston, MA 02215, USA
    Acad Emerg Med 11:143-8. 2004
    ..To determine whether a Web-based educational intervention improves emergency physicians' knowledge about bioterrorism and to survey physicians' knowledge and sources of information on bioterrorism...
  53. ncbi Lumbar puncture ordering and results in the pediatric population: a promising data source for surveillance systems
    Amir Kimia
    Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Acad Emerg Med 13:767-73. 2006
    ..When normal patterns of laboratory test orders and results are modeled, aberrations can be detected. Because many test orders are available electronically well before results, atypical patterns of test ordering may signal outbreaks...
  54. ncbi Influenza and other respiratory virus-related emergency department visits among young children
    Florence T Bourgeois
    Division of Emergency Medicine, Children s Hospital Boston, 300 Longwood Ave, Boston, Massachusetts 02115, USA
    Pediatrics 118:e1-8. 2006
    ..This study provides city- and statewide population estimates of the burden of illness attributable to respiratory viruses for children receiving emergency department-based care for respiratory infections during the winter months...
  55. ncbi Empirical evidence for the effect of airline travel on inter-regional influenza spread in the United States
    John S Brownstein
    Children s Hospital Informatics Program at the Harvard MIT Division of Health Sciences and Technology, Boston, Massachusetts, USA
    PLoS Med 3:e401. 2006
    ..Here, we assess, with empirical data, the role of airline volume on the yearly inter-regional spread of influenza in the United States...
  56. ncbi Privacy protection versus cluster detection in spatial epidemiology
    Karen L Olson
    Children s Hospital Informatics Program, Harvard MIT Division of Health Sciences and Technology, Children s Hospital Boston, Boston, Mass 02215, USA
    Am J Public Health 96:2002-8. 2006
    ..We investigated the effect of varying degrees of address precision (exact latitude and longitude vs the center points of zip code or census tracts) on detection of spatial clusters of cases...
  57. ncbi Incorporating vaccine-preventable disease surveillance into the National Health Information Network: leveraging children's hospitals
    Andrew M Fine
    Division of Emergency Medicine, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
    Pediatrics 118:1431-8. 2006
    ..The purpose of this study was to assess the current practice and feasibility of developing a nationwide network of children's hospitals to conduct surveillance for vaccine preventable diseases...
  58. ncbi Wireless technology infrastructures for authentication of patients: PKI that rings
    Ulrich Sax
    Children s Hospital Informatics Program, 1 Autumn Street AU543, Boston, MA 02115, USA
    J Am Med Inform Assoc 12:263-8. 2005
    ..The authors propose harnessing this technology for the strong authentication of individuals by creating a registration authority and an authentication service, and examine the problems and promise of such a system...
  59. ncbi Using temporal context to improve biosurveillance
    Ben Y Reis
    Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 100:1961-5. 2003
    ..Furthermore, for increased robustness and performance, hybrid systems should be developed to capitalize on the complementary strengths of different types of temporal filters...
  60. ncbi Effects of a law against early postpartum discharge on newborn follow-up, adverse events, and HMO expenditures
    Jeanne M Madden
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    N Engl J Med 347:2031-8. 2002
    ..After the mandate, newborns were less likely to be examined as recommended on day 3 or 4. Because of changes in hospital prices, the two policies had minimal effects on HMO expenditures for hospital and home-based services...
  61. ncbi Newborn screening program practices in the United States: notification, research, and consent
    Kenneth D Mandl
    Children's Hospital Informatics Program, Division of Emergency Medicine, Children's Hospital, Boston, Massachusetts 02115, USA
    Pediatrics 109:269-73. 2002
    ....
  62. ncbi Parents as direct contributors to the medical record: validation of their electronic input
    S C Porter
    Divisions of Emergency Medicine and General Pediatrics, Informatics Program, Children s Hospital, Boston, MA 02115, USA
    Ann Emerg Med 35:346-52. 2000
    ..We assessed the validity and completeness of data in the past medical history (PMH) obtained electronically from parents and examined effects of the human-computer interface and sociodemographic variables on electronic parental report...
  63. ncbi Ultrasonography and limited computed tomography in the diagnosis and management of appendicitis in children
    B M Garcia Peña
    Department of Medicine, Children s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    JAMA 282:1041-6. 1999
    ....
  64. ncbi Is it influenza or anthrax? A decision analytic approach to the treatment of patients with influenza-like illnesses
    Andrew M Fine
    Division of Emergency Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    Ann Emerg Med 43:318-28. 2004
    ..Our results help to highlight the importance of developing rapid and sensitive tests for anthrax and of developing improved surveillance and methods to calculate the previous probability of attacks...
  65. ncbi A Bayesian dynamic model for influenza surveillance
    Paola Sebastiani
    Department of Biostatistics, Boston University, Boston, MA, USA
    Stat Med 25:1803-16; discussion 1817-25. 2006
    ..Our findings show the importance of modelling the complex dynamics of data collected for influenza surveillance, and suggest that dynamic Bayesian networks could be suitable modelling tools for developing epidemic surveillance systems...
  66. ncbi Tectonic shifts in the health information economy
    Kenneth D Mandl
    Children's Hospital Informatics Program at the Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Children's Hospital Boston, Boston, USA
    N Engl J Med 358:1732-7. 2008
  67. ncbi Effects on breastfeeding of changes in maternity length-of-stay policy in a large health maintenance organization
    Jeanne M Madden
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts 02215, USA
    Pediatrics 111:519-24. 2003
    ..CONCLUSIONS: Early postpartum discharge with outpatient breastfeeding support and a home visitor program has no adverse effects on initiation or continuation of breastfeeding...
  68. ncbi Patient-centered design of an information management module for a personally controlled health record
    Colin M Sox
    Department of Pediatrics, Boston Medical Centre and Boston University School of Medicine, Boston, 02118, USA
    J Med Internet Res 12:e36. 2010
    ....
  69. ncbi Length-of-stay policies and ascertainment of postdischarge problems in newborns
    Jeanne M Madden
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts 02215, USA
    Pediatrics 113:42-9. 2004
    ..quot;Ascertainment bias" may have confounded findings in previous reports that raised concerns about the safety of early discharge...
  70. ncbi Running outside the baseline: impact of the 2004 Major League Baseball postseason on emergency department use
    Ben Y Reis
    Ann Emerg Med 46:386-7. 2005
  71. ncbi Roundtable on bioterrorism detection: information system-based surveillance
    William B Lober
    University of Washington, Seattle, Washington, USA
    J Am Med Inform Assoc 9:105-15. 2002
    ..A mailing list server for these ongoing efforts may be found at http://bt.cirg.washington.edu...
  72. ncbi Automated real time constant-specificity surveillance for disease outbreaks
    Shannon C Wieland
    Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA 02139 4307, USA
    BMC Med Inform Decis Mak 7:15. 2007
    ..The usefulness of outbreak detection strategies depends on their specificity; the false alarm rate affects the interpretation of alarms...
  73. ncbi Effect of an imaging protocol on clinical outcomes among pediatric patients with appendicitis
    Barbara M Garcia Peña
    Department of Emergency Medicine, Miami Children s Hospital, Miami, Florida 33155, USA
    Pediatrics 110:1088-93. 2002
    ..We sought to determine the impact of the US-CT protocol on changes in perforation and negative appendectomy rates...
  74. ncbi Density-equalizing Euclidean minimum spanning trees for the detection of all disease cluster shapes
    Shannon C Wieland
    Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA 02139 4307, USA
    Proc Natl Acad Sci U S A 104:9404-9. 2007
    ..Sensitivity and accuracy comparisons with the prevailing cluster detection method show that the method performs similarly on approximately circular historical clusters and greatly improves detection for noncircular clusters...
  75. ncbi No place to hide--reverse identification of patients from published maps
    John S Brownstein
    N Engl J Med 355:1741-2. 2006

Research Grants14

  1. Surveillance and health promotion informatics at work
    Kenneth Mandl; Fiscal Year: 2006
    ..Secondary outcomes will be impact on rates of self-reported illness, and on knowledge, attitudes and beliefs about influenza. The formative evaluation will occur in two test beds, a major US corporation and a Canadian Province. ..
  2. Disease Surveillance in Real Time: Geotemporal Methods
    Kenneth Mandl; Fiscal Year: 2009
    ..Once these methods are established, they can be applied to any other meaningful set of syndromes. ..