Research Topics
| Grace M LeeSummaryAffiliation: Harvard Medical School and Harvard Pilgrim Health Care Country: USA Publications
Research Grants
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Detail Information
Publications
Uptake of meningococcal conjugate vaccine among adolescents in large managed care organizations, United States, 2005: demand, supply and seasonalitySuchita A Lorick
Immunization Services Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
BMC Infect Dis 9:175. 2009..A post hoc analysis was conducted to compare seasonal uptake patterns of MCV4 with polysaccharide meningococcal (MPSV4) and tetanus diphtheria (Td) vaccines...- Adolescent immunizations: missed opportunities for preventionGrace M Lee
Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
Pediatrics 122:711-7. 2008.... - Preferences for health outcomes associated with Group A Streptococcal disease and vaccinationGrace M Lee
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, 133 Brookline Avenue, Boston, MA 02215, USA
Health Qual Life Outcomes 8:28. 2010..g. averted GAS disease vs. vaccine adverse events)... - Epidemiology and risk factors for Staphylococcus aureus colonization in children in the post-PCV7 eraGrace M Lee
Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA, USA
BMC Infect Dis 9:110. 2009..aureus and MRSA colonization in young children in the context of widespread use of PCV7; and (2) examine risk factors for S. aureus colonization in the post-PCV7 era, including the absence of vaccine-type S. pneumoniae colonization... - Gaps in vaccine financing for underinsured children in the United StatesGrace M Lee
Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
JAMA 298:638-43. 2007..In 2000, approximately 14% of children were underinsured for vaccines in the United States... - Quality of life for children and adolescents: impact of HIV infection and antiretroviral treatmentGrace M Lee
Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Pilgrim Health Care, Harvard Medical School, Boston, Massachusetts, USA
Pediatrics 117:273-83. 2006..HIV/AIDS mortality rates in the United States are declining; pediatric HIV has become a chronic disease, with quality of life (QoL) outcomes assuming greater importance... - Cost effectiveness of pertussis vaccination in adultsGrace M Lee
Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts 02215, USA
Am J Prev Med 32:186-193. 2007..Newly available data on pertussis incidence were used to evaluate the cost effectiveness of one-time adult vaccination and adult vaccination with decennial boosters... - H1N1 and seasonal influenza vaccine safety in the vaccine safety datalink projectGrace M Lee
Center for Child Health Care Studies, Department of Population Medicine, Children s Hospital Boston, Boston, Massachusetts, USA
Am J Prev Med 41:121-8. 2011..A robust influenza immunization program in the U.S. requires ongoing monitoring of potential adverse events associated with vaccination... - Health-state valuations for pertussis: methods for valuing short-term health statesGrace M Lee
Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, 133 Brookline Ave, 6th Floor, Boston, MA 02215, USA
Health Qual Life Outcomes 3:17. 2005..S. Our objectives were: (1) to describe patient valuations of pertussis disease and vaccination; and (2) to compare valuations for short-term and long-term health states associated with pertussis... - Pertussis in adolescents and adults: should we vaccinate?Grace M Lee
Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, Massachusetts 02215, USA
Pediatrics 115:1675-84. 2005..Combined acellular pertussis vaccines for adolescents and adults are available in Canada, Australia, and Germany and may soon be considered for use in the United States... - Illness transmission in the home: a possible role for alcohol-based hand gelsGrace M Lee
Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, Massachusetts 02215, USA
Pediatrics 115:852-60. 2005..We also sought to examine potential predictors of reduced illness transmission in the home in a secondary analysis... - Societal costs and morbidity of pertussis in adolescents and adultsGrace M Lee
Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, Boston, MA 02215, USA
Clin Infect Dis 39:1572-80. 2004.... - Adverse events after administration of tetanus-diphtheria-acellular pertussis vaccine to healthcare workersThomas J Sandora
Division of Infectious Diseases, Department of Laboratory Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
Infect Control Hosp Epidemiol 30:389-91. 2009..Systemic adverse events were more common among healthcare workers aged less than 30 years. These findings provide guidance for counseling of healthcare workers who receive Tdap vaccine... - Influenza vaccination in adolescents with high-risk conditionsMari M Nakamura
Department of Ambulatory Care and Prevention, Children s Hospital Boston, Boston, Massachusetts 02115, USA
Pediatrics 122:920-8. 2008..We assessed influenza vaccination rates from 1992 to 2002, individual continuity of vaccination, and missed opportunities for vaccination in adolescents with high-risk conditions... - Acute care and antibiotic seeking for upper respiratory tract infections for children in day care: parental knowledge and day care center policiesJennifer F Friedman
Harvard Pediatric Health Services Research Fellowship Program, The Children's Hospital, Boston, MA, USA
Arch Pediatr Adolesc Med 157:369-74. 2003.... - Near real-time vaccine safety surveillance with partially accrued dataSharon K Greene
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
Pharmacoepidemiol Drug Saf 20:583-90. 2011..We describe practical solutions to these challenges, which were adopted by the VSD Project during pandemic and seasonal influenza vaccine safety surveillance in 2009/2010... - Burden and economic cost of group A streptococcal pharyngitisElizabeth Pfoh
Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Ave, Boston, MA 02215, USA
Pediatrics 121:229-34. 2008..Our aim was to describe the morbidity, medical costs, and nonmedical costs associated with group A streptococcal pharyngitis in school-aged children... - A randomized, controlled trial of a multifaceted intervention including alcohol-based hand sanitizer and hand-hygiene education to reduce illness transmission in the homeThomas J Sandora
Division of Infectious Diseases, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
Pediatrics 116:587-94. 2005..The objective of this study was to determine whether a multifactorial campaign centered on increasing alcohol-based hand sanitizer use and hand-hygiene education reduces illness transmission in the home... - Child care center policies and practices for management of ill childrenJennifer F Friedman
Harvard Pediatric Health Services Research Fellowship Program, Children s Hospital Boston, Boston, MA, USA
Ambul Pediatr 4:455-60. 2004.... - Pneumococcal carriage and antibiotic resistance in young children before 13-valent conjugate vaccinePeter C Wroe
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA
Pediatr Infect Dis J 31:249-54. 2012.... - Tetanus-diphtheria-acellular pertussis vaccination of adults in the USACourtney A Gidengil
Division of Infectious Diseases, Children s Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Expert Rev Vaccines 7:621-34. 2008..Further research is needed to elucidate the role of vaccination in pregnant women and those over 65 years of age, and also to determine whether further booster doses of Tdap are needed... - Higher prevalence of pharyngeal than nasal Staphylococcus aureus carriage in pediatric intensive care unitsMari M Nakamura
Division of Infectious Diseases, Department of Medicine, Children s Hospital Boston, Boston, MA, USA
J Clin Microbiol 48:2957-9. 2010..We examined the sensitivity of nasal and pharyngeal sampling for S. aureus colonization in 331 children admitted to intensive care units. Pharyngeal screening was more sensitive than nasal screening (92.6% versus 63.1%, P < 0.0001)... - Serotype specific invasive capacity and persistent reduction in invasive pneumococcal diseaseInci Yildirim
Department of Pediatrics, Boston University, School of Medicine, Boston, MA, USA
Vaccine 29:283-8. 2010..g. 33F, 22F) as successful colonizers resulting in increased IPD incidence due to replacement serotypes... - Misconceptions about colds and predictors of health service utilizationGrace M Lee
Division of Infectious Diseases, Children s Hospital, Boston, Massachusetts 02115, USA
Pediatrics 111:231-6. 2003..The objective of this study was to determine predictors of reported ED use and ambulatory care use for colds among families with young children... - Financial barriers to implementing combination vaccines: perspectives from pediatricians and policy makersCourtney A Gidengil
Center for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Medical School, Boston Massachusetts, USA
Clin Pediatr (Phila) 48:539-47. 2009..Financial issues for pediatric practices that purchase and provide vaccines for children may be an important barrier to offering combination vaccines... - Antibiotic treatment of children with sore throatJeffrey A Linder
Division of General Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
JAMA 294:2315-22. 2005..Penicillin, amoxicillin, erythromycin, and first-generation cephalosporins are the recommended antibiotics for treatment of sore throat due to GABHS... - Near real-time surveillance for influenza vaccine safety: proof-of-concept in the Vaccine Safety Datalink ProjectSharon K Greene
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Healthcare Institute, 133 Brookline Avenue, Boston, MA 02215 3920, USA
Am J Epidemiol 171:177-88. 2010..Near real-time surveillance for selected adverse events can be implemented prospectively to rapidly assess seasonal and pandemic influenza vaccine safety... - Active influenza vaccine safety surveillance: potential within a healthcare claims environmentJeffrey S Brown
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
Med Care 47:1251-7. 2009..Rapid safety assessment of novel vaccines, especially those targeted against pandemic influenza, is a public health priority... - Cost-effectiveness of adult pertussis vaccination in GermanyGrace M Lee
Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MO 02215, United States
Vaccine 26:3673-9. 2008..The incidence of pertussis in adults is high despite good childhood vaccination coverage. An adult formulation of an acellular pertussis vaccine is licensed and available for use in Germany... - Pertussis vaccination for health care workersThomas J Sandora
Division of Infectious Diseases, Children s Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Clin Microbiol Rev 21:426-34. 2008.... - Financing and systems barriers to seasonal influenza vaccine delivery in community settingsRobert B Penfold
Center for Child Health Care Studies, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, United States
Vaccine 29:9632-9. 2011..Community settings have become increasingly important venues for influenza vaccination. We sought to identify barriers to and solutions for expanding influenza vaccination in community settings... - Epidemiology and risk factors for Clostridium difficile infection in childrenThomas J Sandora
Division of Infectious Diseases, Children s Hospital Boston, Boston, MA 02115, USA
Pediatr Infect Dis J 30:580-4. 2011..Pediatric Clostridium difficile infection (CDI)-related hospitalizations are increasing. We sought to describe the epidemiology of pediatric CDI at a quaternary care hospital... - Outpatient urticaria diagnosis codes have limited predictive value for same-day influenza vaccine adverse event detectionKristen M Moore
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA, USA
J Clin Epidemiol 63:407-11. 2010..To assess the predictive value of claims-based outpatient urticaria diagnosis codes to identify potential vaccine-related adverse events (AEs) when recorded on the same day as influenza vaccination... - Test characteristics of commercial influenza assays for detecting pandemic influenza A (H1N1) in childrenThomas J Sandora
Division of Infectious Diseases, Department of Medicine, Children s Hospital Boston, Boston, MA 02115, USA
Pediatr Infect Dis J 29:261-2. 2010..The sensitivities of BinaxNOW (59.6%) and direct fluorescence antibody (57.3%) were similar. The specificity of each test was >99%... - Perceived impact of the Medicare policy to adjust payment for health care-associated infectionsGrace M Lee
Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, Boston, MA Department of Laboratory Medicine and Division of Infectious Diseases, Children s Hospital Boston, Boston, MA
Am J Infect Control 40:314-9. 2012..We sought to understand the impact of the CMS payment policy on infection prevention efforts... - Signal identification and evaluation for risk of febrile seizures in children following trivalent inactivated influenza vaccine in the Vaccine Safety Datalink Project, 2010-2011Alison Tse
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA 02215, United States
Vaccine 30:2024-31. 2012..Because of the importance of preventing influenza and pneumococcal infections and associated complications, our findings should be placed in a benefit-risk framework to ensure that population health benefits are maximized... - Projected cost-effectiveness of new vaccines for adolescents in the United StatesIsmael R Ortega-Sanchez
National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Mail Stop A 47, Atlanta, GA 30333, USA
Pediatrics 121:S63-78. 2008..However, important considerations that limit the utility of these assessments, such as the diversity of approaches used, are often overlooked and should be better understood... - Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants recommendations of the Advisory Committee on Immunization Practices (ACIP)Trudy V Murphy
Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Atlanta, GA 30333, USA
MMWR Recomm Rep 57:1-51. 2008.... - Preventing tetanus, diphtheria, and pertussis among adults: use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine recommendations of the Advisory Committee on Immunization Practices (ACIP) and recommendation of ACIP, supported bKatrina Kretsinger
Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, CDC, Atlanta, GA 30333, USA
MMWR Recomm Rep 55:1-37. 2006.... - Varicella vaccination in adults: is it cost-effective?Grace M Lee
Clin Infect Dis 44:1049-50. 2007 - Changing epidemiology of acute rheumatic fever in the United StatesGrace M Lee
Clin Infect Dis 42:448-50. 2006
Research Grants
- Intended and Unintended Consequences of Nonpayment for Preventable ComplicationsGrace Lee; Fiscal Year: 2009..g. for-profit vs. not-for-profit); and (4) To assess whether reduced reimbursement for HAIs as a result of NPPC disproportionately affects hospitals that care for a high proportion of poor or minority patients. ..
- Intended and Unintended Consequences of Nonpayment for Preventable ComplicationsGrace M Lee; Fiscal Year: 2010..g. for-profit vs. not-for-profit);and (4) To assess whether reduced reimbursement for HAIs as a result of NPPC disproportionately affects hospitals that care for a high proportion of poor or minority patients. ..