Research Topics
| L L LeapeSummaryAffiliation: Harvard University Country: USA Publications
| Collaborators
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Detail Information
Publications
Medication safety in the ambulatory chemotherapy settingTejal K Gandhi
Division of General Internal Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
Cancer 104:2477-83. 2005..Little is known concerning the safety of the outpatient chemotherapy process. In the current study, the authors sought to identify medication error and potential adverse drug event (ADE) rates in the outpatient chemotherapy setting...
Reducing adverse drug events: lessons from a breakthrough series collaborativeL L Leape
Harvard School of Public Health, Boston, MA 02115, USA
Jt Comm J Qual Improv 26:321-31. 2000....
Assessing the level of healthcare information technology adoption in the United States: a snapshotEric G Poon
Division of General Medicine and Primary Care, Brigham and Women s Hospital, Boston, MA, USA
BMC Med Inform Decis Mak 6:1. 2006..Comprehensive knowledge about the level of healthcare information technology (HIT) adoption in the United States remains limited. We therefore performed a baseline assessment to address this knowledge gap...
Transforming healthcare: a safety imperativeL Leape
Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
Qual Saf Health Care 18:424-8. 2009..In future roundtable sessions, the Institute will further elaborate on the meaning of each concept, identify the challenges to implementation, and issue recommendations for policy makers, organizations, and healthcare professionals...
Five years after To Err Is Human: what have we learned?Lucian L Leape
Department of Health Policy and Management, Harvard School of Public Health, Boston, Mass 02215, USA
JAMA 293:2384-90. 2005..The Agency for Healthcare Research and Quality should bring together all stakeholders, including payers, to agree on a set of explicit and ambitious goals for patient safety to be reached by 2010...
Ethical issues in patient safetyLucian L Leape
Harvard School of Public Health, Department of Health Policy and Management, Boston, MA 02215, USA
Thorac Surg Clin 15:493-501. 2005..This is an immense challenge. It is not easy to "first, do no harm." But only we as a profession can meet this challenge. No one else can do it; we must...
Problem doctors: is there a system-level solution?Lucian L Leape
Harvard School of Public Health and Harvard Medical School, Boston, Massachusetts 02215, USA
Ann Intern Med 144:107-15. 2006....
Full disclosure and apology--an idea whose time has comeLucian L Leape
Harvard University, USA
Physician Exec 32:16-8. 2006
Developing and implementing new safe practices: voluntary adoption through statewide collaborativesL L Leape
Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
Qual Saf Health Care 15:289-95. 2006..In a statewide initiative we developed a framework for (1) selecting two safe practices, (2) developing operational details of implementation, (3) enlisting hospitals to participate, and (4) facilitating implementation...
Adherence to practice guidelines: the role of specialty society guidelinesLucian L Leape
Department of Health Policy and Management, Harvard School of Public Health, Boston, Mass 02115, USA
Am Heart J 145:19-26. 2003..We investigated whether physician adherence to guidelines for percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass grafting (CABG) varied by source, development methods, or the extent of their evidence-base...
When good doctors go bad: a systems problemLucian L Leape
Harvard Medical School, Boston, MA 02115, USA
Ann Surg 244:649-52. 2006
Scope of problem and history of patient safetyLucian L Leape
Harvard School of Public Health, Boston, MA 02115, USA
Obstet Gynecol Clin North Am 35:1-10, vii. 2008..This article addresses the issue of patient safety, discussing its history, and organizations and practices that are helping to make it more of a reality in today's health care environment...
What practices will most improve safety? Evidence-based medicine meets patient safetyLucian L Leape
Department of Health Policy and Management, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
JAMA 288:501-7. 2002
Errors in medicineLucian L Leape
Harvard School of Public Health, Boston, MA 02115, United States
Clin Chim Acta 404:2-5. 2009..We move our models of care from reliance on independent, individual performance excellence to interdependent, collaborative, interprofessional teamwork; 6. Accountability is universal and reciprocal, not top-down...
Rating recommendations for consumers about patient safety: sense, common sense, or nonsense?Saul N Weingart
Center for Patient Safety, Dana Farber Cancer Institute, Boston, USA
Jt Comm J Qual Patient Saf 35:206-15. 2009..Although many organizations offer advice about the consumer's role in improving patient safety, little is known about these recommendations...
Race and gender disparities in rates of cardiac revascularization: do they reflect appropriate use of procedures or problems in quality of care?Arnold M Epstein
Division of General Medicine Section on Health Services and Policy Research, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Med Care 41:1240-55. 2003..However, few studies have examined whether these differences reflect problems in quality of care...
Patient-reported medication symptoms in primary careSaul N Weingart
Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Boston, MA, USA
Arch Intern Med 165:234-40. 2005....
Reducing the frequency of errors in medicine using information technologyD W Bates
Harvard Medical School, Boston, Massachusetts, USA
J Am Med Inform Assoc 8:299-308. 2001..Washington, DC: National Academy Press, 1999) described the magnitude of the problem, and the public interest in this issue, which was already large, has grown...
Robert E. Gross Lecture. Making health care safe: are we up to it?Lucian L Leape
Department of Health Policy and Management, Harvard School of Public Health, Boston, MA 02115, USA
J Pediatr Surg 39:258-66. 2004
Patient risk factors for adverse drug events in hospitalized patients. ADE Prevention Study GroupD W Bates
Department of Medicine, Brigham and Women s Hospital, Boston, Mass 02115, USA
Arch Intern Med 159:2553-60. 1999..Adverse drug events (ADEs) are common in hospitalized patients, but few empirical data are available regarding the strength of patient risk factors for ADEs...
Preventable medical injuries in older patientsJ M Rothschild
Division of General Medicine, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
Arch Intern Med 160:2717-28. 2000..The success of intervention varies by type of complications. For medications, various interventions have been successful, and fall prevention programs have been demonstrated to be effective in the nursing home and home...
Communicating critical test results: safe practice recommendationsDoris Hanna
Massachusetts Coalition for the Prevention of Medical Errors, Boston, USA
Jt Comm J Qual Patient Saf 31:68-80. 2005..Hospitals' team members tested changes and shared successful strategies that improved the reliability of communicating critical test results. An evaluation of the results of this collaborative is underway...
Incidence of adverse events and negligence in hospitalized patients: results of the Harvard Medical Practice Study I. 1991T A Brennan
Division of General Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA
Qual Saf Health Care 13:145-51; discussion 151-2. 2004..0001), but no differences in the percentage due to negligence. CONCLUSIONS: There is a substantial amount of injury to patients from medical management, and many injuries are the result of substandard care...
Racial differences in cardiac revascularization rates: does "overuse" explain higher rates among white patients?E C Schneider
Department of Health Policy and Management, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115
Ann Intern Med 135:328-37. 2001..Overuse of cardiac revascularization varied significantly by geographic region...
Reporting of adverse eventsLucian L Leape
Harvard School of Public Health, Boston, USA
N Engl J Med 347:1633-8. 2002
Adverse drug events in ambulatory careTejal K Gandhi
Division of General Internal Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
N Engl J Med 348:1556-64. 2003..However, few data are available on adverse drug events among outpatients. We conducted a study to determine the rates, types, severity, and preventability of such events among outpatients and to identify preventive strategies...
Outpatient prescribing errors and the impact of computerized prescribingTejal K Gandhi
Division of General Internal Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
J Gen Intern Med 20:837-41. 2005..Medication errors are common among inpatients and many are preventable with computerized prescribing. Relatively little is known about outpatient prescribing errors or the impact of computerized prescribing in this setting...
Reconciling medications at admission: safe practice recommendations and implementation strategiesGina Rogers
Massachusetts Coalition for the Prevention of Medical Errors, Burlington, USA
Jt Comm J Qual Patient Saf 32:37-50. 2006..Fifty hospitals collaborated in a patient safety initiative developed and implemented by the Massachusetts Coalition for the Prevention of Medical Errors and the Massachusetts Hospital Association...
The godfather of patient safety sees progress. Interview by Mark CraneLucian L Leape
Med Econ 80:29-30, 33-4. 2003
Reliability of clinical guideline development using mail-only versus in-person expert panelsDonna L Washington
VA Greater Los Angeles Healthcare System, Los Angeles, California 90073, USA
Med Care 41:1374-81. 2003..The RAND-UCLA Appropriateness Method is one commonly used method for collecting expert opinion. We tested whether a less expensive, mail-only process could substitute for the standard in-person process normally used...
Doing better with critical test resultsDavid W Bates
Jt Comm J Qual Patient Saf 31:66-7, 61. 2005..Health care should achieve the goals that no critical test result is lost and that all such results are managed with a speed appropriate to their urgency...
Errors are not diseases: they are symptoms of diseasesLucian L Leape
Laryngoscope 114:1320-1. 2004
Striving for perfectionLucian L Leape
Clin Chem 48:1871-2. 2002
Regionalization and the underuse of angiography in the Veterans Affairs Health Care System as compared with a fee-for-service systemLaura A Petersen
Houston Center for Quality of Care and Utilization Studies, Houston Veterans Affairs Medical Center, and the Section for Health Services Research, Baylor College of Medicine, Houston, TX 77030, USA
N Engl J Med 348:2209-17. 2003..Further work should focus on how regionalization policies could be improved with effective referral and triage processes...
Is it defensible to use volume standards for purchasing care?Lucian L Leape
Ann Surg 238:168-9. 2003
An interview with Lucian LeapeLucian L Leape
Jt Comm J Qual Saf 30:653-8. 2004
