Research Topics
| J HuebnerSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Coagulase-negative staphylococci: role as pathogensJ Huebner
Dept of Infectious Diseases, Children s Hospital, Boston, Massachusetts, USA
Annu Rev Med 50:223-36. 1999..Intravenous treatment of systemic infections is usually required because coagulase-negative staphylococci have become increasingly resistant to multiple antibiotics...
Prophylactic and therapeutic efficacy of antibodies to a capsular polysaccharide shared among vancomycin-sensitive and -resistant enterococciJ Huebner
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Infect Immun 68:4631-6. 2000..These data indicate that CP antigens from enterococci are potential targets of protective antibodies and that these antibodies may be useful for prophylaxis and treatment of enterococcal infections...
Distribution of four capsular serotypes of Enterococcus faecalis among clinical isolates from different geographical origins and infection sitesM Hufnagel
Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
Infection 34:22-5. 2006..CONCLUSION: Half of the strain collection could be typed with four serotype-specific sera. No serotype from a given country or infection site clearly predominated...
Control of multiply resistant cocci: do international comparisons help?S Harbarth
Children s Hospital, and Harvard Medical School, Boston, USA
Lancet Infect Dis 1:251-61. 2001..Finally, we suggest that a macro-level perspective on antibiotic resistance can broaden the understanding of this worldwide calamity, and help prevent further dissemination of multiply resistant microorganisms...
Structure of an antigenic teichoic acid shared by clinical isolates of Enterococcus faecalis and vancomycin-resistant Enterococcus faeciumY Wang
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115 5804, USA
Carbohydr Res 316:155-60. 1999..It was composed of glucose, glycerol, and phosphate as determined by chemical and GC-MS analysis. The repeating-unit structure was elucidated by a series of 1H, 13C, and 31P NMR spectroscopy to be the following: [formula: see text]..
Analysis of the specific immune response against capsular polysaccharides of two patients with systemic enterococcal infectionsM Hufnagel
Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
Infection 33:373-6. 2005..We conclude, therefore, that systemic infection with enterococci does not lead to higher antibody concentrations or better opsonic killing against the causative capsular serotype...
In vitro assessment of the host response against Enterococcus faecalis used in probiotic preparationsA Kropec
Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
Infection 33:377-9. 2005..This information may be helpful in assessing the safety of a given bacterial isolate used and could detect likely enterococcal candidates for probiotic preparations...
