Research Topics
Species | Jhodie R DuncanSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
The effect of maternal smoking and drinking during pregnancy upon (3)H-nicotine receptor brainstem binding in infants dying of the sudden infant death syndrome: initial observations in a high risk populationJhodie R Duncan
Department of Pathology, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
Brain Pathol 18:21-31. 2008..Future studies are needed to establish the role of adverse prenatal exposures in altered brainstem neurochemistry in SIDS...
The development of nicotinic receptors in the human medulla oblongata: inter-relationship with the serotonergic systemJhodie R Duncan
Department of Pathology, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
Auton Neurosci 144:61-75. 2008..This study indicates parallel dynamic and complex changes in the medullary nicotinic and 5-HT systems throughout early life, i.e., the period of risk for SIDS...
Brainstem deficiency of the 14-3-3 regulator of serotonin synthesis: a proteomics analysis in the sudden infant death syndromeKevin G Broadbelt
Department of Pathology, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts
Mol Cell Proteomics 11:M111.009530. 2012..These data suggest a potential molecular defect in SIDS related to TPH2 regulation, as 14-3-3 is critical in this process...
Prenatal nicotine-exposure alters fetal autonomic activity and medullary neurotransmitter receptors: implications for sudden infant death syndromeJhodie R Duncan
Dept of Pathology, Enders 1112 1, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
J Appl Physiol 107:1579-90. 2009..Thus increased risk for SIDS due to maternal smoking may be partly related to the effects of nicotine on 5-HT and/or nicotinic receptors...
Brainstem serotonergic deficiency in sudden infant death syndromeJhodie R Duncan
Department of Pathology, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
JAMA 303:430-7. 2010..Abnormalities of serotonin (5-hydroxytryptamine [5-HT]) receptor binding in regions of the medulla oblongata involved in this control have been reported in infants dying from SIDS...
