Research Topics
Species | Micah J BensonSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Distinction of the memory B cell response to cognate antigen versus bystander inflammatory signalsMicah J Benson
Department of Microbiology and Immunology, Dartmouth Medical School and Norris Cotton Cancer Center, Lebanon, NH 03756, USA
J Exp Med 206:2013-25. 2009..The absence of a B(MEM) response to nonspecific inflammatory signals clearly shows that B(MEM) proliferation and differentiation is a process tightly controlled by the availability of cognate antigen...
Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRILMicah J Benson
Department of Microbiology and Immunology, Dartmouth Medical School, The Norris Cotton Cancer Center, Lebanon, NH 03756, USA
J Immunol 180:3655-9. 2008..These data define the BAFF/APRIL-dependent and -independent components of long-lived humoral immunity...
Molecular mechanism and function of CD40/CD40L engagement in the immune systemRaul Elgueta
Department of Microbiology and Immunology, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
Immunol Rev 229:152-72. 2009..Lastly, we discuss the role of CD40 as a target in harnessing anti-tumor immunity. This review underscores the essential role CD40 plays in adaptive immunity...
Affinity of antigen encounter and other early B-cell signals determine B-cell fateMicah J Benson
Department of Microbiology and Immunology, Dartmouth Medical School, Lebanon, NH 03756, USA
Curr Opin Immunol 19:275-80. 2007..We hypothesize that graded interferon regulatory factor-4 levels driven by signals to B cells, including B-cell receptor signal strength, are responsible for this branch point in the B-cell terminal differentiation pathway...
Strategies for selective priming of memory B cellsVanitha S Raman
Department of Microbiology and Immunology, Dartmouth Medical School, Lebanon, NH 03756, USA
Immunol Lett 109:93-100. 2007..Furthermore, these studies suggest that the signals that govern the expansion and differentiation of B(mem) can be uncoupled from those that induce long-lived BM PCs...
B cell survival: an unexpected mechanism of lymphocyte vitalityMicah J Benson
Department of Microbiology and Immunology, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
Immunol Cell Biol 86:485-6. 2008
Retinoic acid in the immune systemKarina Pino-Lagos
Department of Microbiology and Immunology, Dartmouth College, Dartmouth Medical School, Lebanon, NH 03756, USA
Ann N Y Acad Sci 1143:170-87. 2008..Historically, vitamin A deprivation and repletion and RA agonists have been shown to profoundly affect immunity. Now these findings can be interpreted in light of the revelations that RA controls leukocyte homing and T(reg) function...
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulationMicah J Benson
Department of Microbiology and Immunology, Dartmouth Medical School and Norris Cotton Cancer Center, Lebanon, NH 03756, USA
J Exp Med 204:1765-74. 2007....
