Research Topics
| I R ArkhipovaSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Retroelements containing introns in diverse invertebrate taxaIrina R Arkhipova
Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA
Nat Genet 33:123-4. 2003..The ability of Penelope-like elements (PLEs) to retain introns, their separate phylogenetic placement and their peculiar structural features make them a novel class of eukaryotic retroelements...
Massive horizontal gene transfer in bdelloid rotifersEugene A Gladyshev
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
Science 320:1210-3. 2008..One such gene, apparently of bacterial origin, was overexpressed in Escherichia coli and yielded an active enzyme. The capture and functional assimilation of exogenous genes may represent an important force in bdelloid evolution...
Diverse DNA transposons in rotifers of the class BdelloideaIrina R Arkhipova
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138 2019, USA
Proc Natl Acad Sci U S A 102:11781-6. 2005....
[Transposable elements in the Animal Kingdom]I R Arkhipova
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
Mol Biol (Mosk) 35:196-207. 2001....
Three retrotransposon families in the genome of Giardia lamblia: two telomeric, one deadI R Arkhipova
Department of Molecular and Cellular Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA
Proc Natl Acad Sci U S A 98:14497-502. 2001..Thus, the entire genome of this protozoan, which is not known to reproduce sexually, contains only retrotransposons that are either confined to telomeric regions and possibly beneficial, or inactivated and completely nonfunctional...
Distribution and phylogeny of Penelope-like elements in eukaryotesIrina R Arkhipova
Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA
Syst Biol 55:875-85. 2006....
Mobile genetic elements and sexual reproductionI R Arkhipova
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
Cytogenet Genome Res 110:372-82. 2005....
Deleterious transposable elements and the extinction of asexualsIrina Arkhipova
Department of Molecular and Cellular Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA
Bioessays 27:76-85. 2005....
Complex patterns of transcription of a Drosophila retrotransposon in vivo and in vitro by RNA polymerases II and IIII R Arkhipova
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138 2092, USA
Nucleic Acids Res 23:4480-7. 1995..A possible role of pol III transcription in mechanisms controlling the expression of full-length mdg1-encoded transcripts in the developing fly, which are apparently relaxed in cell culture, is discussed...
A deep-branching clade of retrovirus-like retrotransposons in bdelloid rotifersEugene A Gladyshev
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
Gene 390:136-45. 2007..We describe the retrovirus-like structure of the new elements, containing gag, pol, and env-like open reading frames, and discuss their possible origins, transmission, and behavior in bdelloid genomes...
Telomere-associated endonuclease-deficient Penelope-like retroelements in diverse eukaryotesEugene A Gladyshev
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
Proc Natl Acad Sci U S A 104:9352-7. 2007....
Reverse transcriptase and endonuclease activities encoded by Penelope-like retroelementsKonstantin I Pyatkov
Institute of Cell Biophysics, Pushchino 142290, Russia
Proc Natl Acad Sci U S A 101:14719-24. 2004..We propose that the Penelope EN cleaves the target DNA during transposition, generating a primer for reverse transcription. Our results show that an active Uri EN has been adopted by a retrotransposon...
