Research Topics
Genomes and Genes | Kate G AckermanSummaryAffiliation: Harvard University Country: USA Publications
Research Grants
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Detail Information
Publications
Gata4 is necessary for normal pulmonary lobar developmentKate G Ackerman
Division of Genetics, Brigham and Women s Hospital, Harvard Medical School New Research Building 458, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
Am J Respir Cell Mol Biol 36:391-7. 2007..Fog2 and Gata4 in the early pulmonary mesenchyme participate in patterning the secondary bronchus of the accessory lobe...- Development of the diaphragm and genetic mouse models of diaphragmatic defectsKate G Ackerman
Division of Genetics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Am J Med Genet C Semin Med Genet 145:109-16. 2007..However, at this time we do not have enough knowledge to make more mechanistic or genetic classifications though with time, genetic progress in the field of diaphragm development will allow us to do this... - Congenital diaphragmatic hernia candidate genes derived from embryonic transcriptomesMeaghan K Russell
Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Boston, MA 02114, USA
Proc Natl Acad Sci U S A 109:2978-83. 2012.... - Infants with Bochdalek diaphragmatic hernia: sibling precurrence and monozygotic twin discordance in a hospital-based malformation surveillance programBarbara R Pober
Genetics and Teratology, MassGeneral Hospital for Children, Boston, Massachusetts, USA
Am J Med Genet A 138:81-8. 2005..The twin data also raise the possibility that epigenetic abnormalities contribute to the development of CDH... - Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heartBin Zhou
Department of Cardiology, Children s Hospital Boston and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA
J Clin Invest 119:1462-76. 2009..Loss of the FOG2 or FOG2-GATA4 interaction altered the expression of a panel of angiogenesis-related genes. Collectively, our data indicate that FOG2 regulates adult heart function and coronary angiogenesis... - The naive airway hyperresponsiveness of the A/J mouse is Kit-mediatedEmily Cozzi
Division of Genetics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 108:12787-92. 2011..Remarkably, introduction of the Vga9 Mitf mutation into the A/J background resulted in the ablation of MCs but did not ameliorate AHR. These results indicate that c-Kit is required for development of AHR in an MC-independent fashion... - Characterization of the chromosome 1q41q42.12 region, and the candidate gene DISP1, in patients with CDHSibel Kantarci
Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Am J Med Genet A 152:2493-504. 2010.... - Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in miceXiaoli Liu
Pulmonary and Critical Care Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
Circulation 119:261-8. 2009..Depending on the cell type, Speg isoforms may serve as markers of striated or smooth muscle differentiation... - Congenital diaphragmatic hernia and pulmonary hypoplasia: new insights from developmental biology and geneticsKate G Ackerman
Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
Am J Med Genet C Semin Med Genet 145:105-8. 2007 - Interacting genetic loci cause airway hyperresponsivenessKate G Ackerman
Division of Genetics, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Physiol Genomics 21:105-11. 2005....
Research Grants
- Role of Fog2 in Lung and Diaphragm DevelopmentKate Ackerman; Fiscal Year: 2007..She is a well supported candidate who will benefit highly from a Clinical Scientist Development Award. ..