Research Topics
| William L BakerSummaryAffiliation: Hartford Hospital Country: USA Publications
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Detail Information
Publications
Azithromycin for the secondary prevention of coronary artery disease: a meta-analysisWilliam L Baker
School of Pharmacy, University of Connecticut, Storrs, and Division of Cardiology, Hartford Hospital 06102, USA
Am J Health Syst Pharm 64:830-6. 2007..A meta-analysis of randomized, controlled trials that evaluated the effect of the macrolide antibiotic, azithromycin, on clinical outcomes in patients with coronary artery disease (CAD) was conducted...- Probable enoxaparin-induced hepatotoxicityErica L Baker
Evidence Based Practice Center, Hartford Hospital, Hartford, CT, USA
Am J Health Syst Pharm 66:638-41. 2009..A case of probable enoxaparin-induced hepatotoxicity is described... - The role of soluble fiber in the management of patients with hypercholesterolemia: a review of the literatureWilliam L Baker
Evidence-based Practice Center, Hartford Hospital, USA
Conn Med 72:465-8. 2008 - Role of prasugrel, a novel P2Y(12) receptor antagonist, in the management of acute coronary syndromesWilliam L Baker
Evidence Based Practice Center, Hartford Hospital, Hartford, Connecticut 06102 5037, USA
Am J Cardiovasc Drugs 9:213-29. 2009.... - Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors or angiotensin II-receptor blockers for ischemic heart diseaseWilliam L Baker
University of Connecticut Hartford Hospital Evidence Based Practice Center, 80 Seymour Street, Hartford, CT 06102, USA
Ann Intern Med 151:861-71. 2009..Patients with ischemic heart disease and preserved ventricular function experience considerable morbidity and mortality despite standard medical therapy... - Differing effect of statins on insulin sensitivity in non-diabetics: a systematic review and meta-analysisWilliam L Baker
University of Connecticut School of Pharmacy, Storrs, CT, USA
Diabetes Res Clin Pract 87:98-107. 2010..To determine whether individual statins had differing effects on insulin sensitivity (IS) in patients without pre-existing diabetes mellitus... - The effect of adding plant sterols or stanols to statin therapy in hypercholesterolemic patients: systematic review and meta-analysisJennifer M Scholle
University of Connecticut School of Pharmacy, and Director, Pharmacoeconomics and Outcomes Studies Group, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102 5037, USA
J Am Coll Nutr 28:517-24. 2009..To characterize the effect of plant sterols/stanols on serum lipids in hypercholesterolemic patients on concurrent statin therapy, we conducted a meta-analysis of randomized controlled trials... - Association between CHADS?risk factors and anticoagulation-related bleeding: a systematic literature reviewWendy T Chen
University of Connecticut School of Pharmacy, Storrs, CT, USA
Mayo Clin Proc 86:509-21. 2011.... - The effect of plant sterols or stanols on lipid parameters in patients with type 2 diabetes: a meta-analysisWilliam L Baker
The Evidence Based Practice Center, Hartford Hospital, Hartford, CT 06102 5037, United States
Diabetes Res Clin Pract 84:e33-7. 2009..Upon meta-analysis, plant sterols/stanols significantly reduced total and LDL cholesterol, with a trend towards improvement in HDL. No beneficial effect on triglycerides was apparent... - The association among blood transfusions, white blood cell count, and the frequency of post-cardiothoracic surgery atrial fibrillation: a nested cohort study from the Atrial Fibrillation Suppression Trials I, II, and IIINitesh Sood
Division of Cardiology, Hartford Hospital, Hartford, CT 06102, USA
J Cardiothorac Vasc Anesth 23:22-7. 2009..To evaluate the impact of postoperative red blood cell transfusions and white blood cell (WBC) counts on post-cardiothoracic surgery atrial fibrillation... - Effect of ascorbic acid on inflammatory markers after cardiothoracic surgeryJennifer A Colby
Hartford Hospital, CT 06102, USA
Am J Health Syst Pharm 68:1632-9. 2011..The effect of ascorbic acid on inflammatory markers after cardiothoracic surgery (CTS) was studied... - The effects of barley-derived soluble fiber on serum lipidsRipple Talati
University of Connecticut School of Pharmacy, Storrs, Connecticut, USA
Ann Fam Med 7:157-63. 2009..We wanted to determine the association between consumption of barley and changes in plasma lipids in healthy and hypercholesterolemic men and women... - Combination therapy for the management of hypertension: A review of the evidenceNitesh Sood
Department of Cardiology, Hartford Hospital, CT, USA
Am J Health Syst Pharm 67:885-94. 2010..Evidence regarding combination therapy for the management of hypertension is reviewed... - A meta-analysis evaluating the impact of chitosan on serum lipids in hypercholesterolemic patientsWilliam L Baker
University of Connecticut School of Pharmacy, Storrs, CT, USA
Ann Nutr Metab 55:368-74. 2009..To better characterize the impact of chitosan on serum lipids in hypercholesterolemic patients, we performed a meta-analysis of randomized controlled trials... - Efficacy and Safety of Innovator versus Generic Drugs in Patients with Epilepsy: A Systematic ReviewRipple Talati
From the University of Connecticut Hartford Hospital, Evidence Based Practice Center, Hartford, Connecticut
Pharmacotherapy 32:314-22. 2012.... - Pharmacologic treatments for chronic obstructive pulmonary disease: a mixed-treatment comparison meta-analysisWilliam L Baker
Hartford Hospital Drug Information Center, Hartford, Connecticut 06102 5037, USA
Pharmacotherapy 29:891-905. 2009..To assess the comparative efficacy of pharmacologic agents for the maintenance treatment of chronic obstructive pulmonary disease (COPD)... - Improved glucose control associated with i.v. chromium administration in two patients receiving enteral nutritionOlivia J Phung
University of Connecticut UC Hartford Hospital HH Evidence Based Practice Center, Hartford, CT 06102 5037, USA
Am J Health Syst Pharm 67:535-41. 2010..The effect of i.v. chromium administration on glucose control in two patients receiving enteral nutrition is described... - Effect of magnesium L-lactate on blood pressure in patients with an implantable cardioverter defibrillatorWilliam L Baker
Evidence Based Practice Center, Hartford, CT, USA
Ann Pharmacother 43:569-76. 2009..Previous studies have evaluated the impact of oral magnesium on blood pressure; however, they used magnesium salts with low bioavailability, had methodological issues, and showed differing results... - Antihypertensive medication and their impact on cancer incidence: a mixed treatment comparison meta-analysis of randomized controlled trialsCraig I Coleman
University of Connecticut, School of Pharmacy, Hartford, Connecticut 06102 5037, USA
J Hypertens 26:622-9. 2008..The aim of this article is to determine the association between commonly used antihypertensive agents and the incidence of cancer... - Intravenous hydralazine for blood pressure management in the hospitalized patient: its use is often unjustifiedPatrick Campbell
Division of Hypertension and Clinical Pharmacology, Calhoun Cardiology Center, Farmington, CT, USA
J Am Soc Hypertens 5:473-7. 2011..Thus, this agent may not be useful for treating hypertension in many hospitalized patients and may cause harm if used inappropriately... - Effect of cinnamon on glucose control and lipid parametersWilliam L Baker
Department of Pharmacy Practice, School of Pharmacy, University of Connecticut, Storrs, Connecticut, USA
Diabetes Care 31:41-3. 2008..To perform a meta-analysis of randomized controlled trials of cinnamon to better characterize its impact on glucose and plasma lipids... - Effect of green tea catechins with or without caffeine on anthropometric measures: a systematic review and meta-analysisOlivia J Phung
University of Connecticut School of Pharmacy, Storrs, CT, USA
Am J Clin Nutr 91:73-81. 2010..Green tea catechins (GTCs) with or without caffeine have been studied in randomized controlled trials (RCTs) for their effect on anthropometric measures and have yielded conflicting results... - Prasugrel: a critical comparison with clopidogrelKurt M Reinhart
Department of Pharmacy, Hartford Hospital, Hartford, Connecticut 06102, USA
Pharmacotherapy 29:1441-51. 2009..Given the totality of data available, prasugrel appears to be a promising treatment option for patients with acute coronary syndromes who are undergoing percutaneous coronary interventions... - Dopamine agonists in the treatment of early Parkinson's disease: a meta-analysisWilliam L Baker
School of Pharmacy, University of Connecticut, CT, USA
Parkinsonism Relat Disord 15:287-94. 2009.... - Feverfew for migraine prophylaxis: a systematic reviewElisa Saranitzky
University of Connecticut, School of Pharmacy, Storrs, Connecticut, USA
J Diet Suppl 6:91-103. 2009..Pharmacologically, there is some potential for concern with long-term dosing given its cyclooxygenase-2 inhibiting effects and longer-term studies will be needed to ameliorate these concerns in coronary disease patients... - The development of new-onset type 2 diabetes associated with choosing a calcium channel blocker compared to a diuretic or beta-blockerEffie L Kuti
School of Pharmacy, University of Connecticut, Storrs, CT, USA
Curr Med Res Opin 23:1239-44. 2007..Pharmacologic data has shown improved insulin sensitivity with ACEIs and ARBs. Controversy persists regarding the influence of calcium channel blockers on the development of new-onset diabetes... - Effect of nonergot dopamine agonists on symptoms of restless legs syndromeWilliam L Baker
University of Connecticut School of Pharmacy, Storrs, Connecticut, USA
Ann Fam Med 6:253-62. 2008..We performed a meta-analysis of randomized placebo-controlled trials of nonergot dopamine agonists (NEDAs) for the treatment of restless legs syndrome... - Effect of glucomannan on plasma lipid and glucose concentrations, body weight, and blood pressure: systematic review and meta-analysisNitesh Sood
University of Connecticut Schools of Medicine and Drug Information, Hartford Hospital, Hartford, CT 06102 5037, USA
Am J Clin Nutr 88:1167-75. 2008..Several clinical trials have investigated the impact of glucomannan on plasma lipids, body weight, fasting blood glucose (FBG), and blood pressure (BP), but have yielded conflicting results and had only modest sample sizes... - Use of N-acetylcysteine to reduce post-cardiothoracic surgery complications: a meta-analysisWilliam L Baker
University of Connecticut School of Pharmacy, Storrs, CT, USA
Eur J Cardiothorac Surg 35:521-7. 2009..Currently, the most compelling data for using NAC in CTS patients is in post-CTS AF prevention. However, additional, larger randomized controlled trials evaluating this and other postoperative complication endpoints are needed... - Assessing the usefulness of health-related quality-of-life trials: a clinician's perspective using two COPD examplesOlivia J Phung
University of Connecticut Hartford Hospital Evidence Based Practice Center, Hartford, CT 06102, USA
Ann Pharmacother 43:1496-505. 2009..To empower clinicians to discern when health-related quality-of-life (HRQoL) evidence from a single trial, or from constituent trials within a systematic review or meta-analysis, is compelling enough to alter clinical practice... - Meta-analysis to assess the quality of warfarin control in atrial fibrillation patients in the United StatesWilliam L Baker
University of Connecticut Hartford Hospital Evidence Based Practice Center, Hartford, CT 06102, USA
J Manag Care Pharm 15:244-52. 2009.... - Dabigatran: an oral direct thrombin inhibitor for use in atrial fibrillationStephen D Bendel
Schools of Pharmacy and Medicine, Storrs and Farmington CT and Department of Hematology Oncology, University of Connecticut, Farmington, USA
Adv Ther 28:460-72. 2011..Dabigatran offers a unique alternative to warfarin in patients with nonvalvular AF and can be beneficial in patients requiring anticoagulation therapy... - Effect of perioperative corticosteroid use on the incidence of postcardiothoracic surgery atrial fibrillation and length of stayWilliam L Baker
University of Connecticut School of Pharmacy, Storrs, Connecticut, USA
Heart Rhythm 4:461-8. 2007..Corticosteroids have been traditionally used to reduce inflammation, and when administered perioperatively, they may decrease the incidence of atrial fibrillation... - Renin-angiotensin system inhibitors for prevention of new-onset atrial fibrillationWilliam L Baker
University of Connecticut School of Pharmacy, Division of Cardiology and Drug Information, Hartford Hosptial, Hartford, USA
Conn Med 71:205-9. 2007 - Increased clinical failures when treating acute otitis media with macrolides: a meta-analysisJoshua D Courter
Connecticut Children s Medical Center, Hartford, CT 06106, USA
Ann Pharmacother 44:471-8. 2010.... - Azilsartan medoxomil: a new angiotensin II receptor antagonist for treatment of hypertensionWilliam L Baker
School of Pharmacy, University of Connecticut, Farmington, CT, USA
Ann Pharmacother 45:1506-15. 2011.... - Pitavastatin: a new 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor for the treatment of hyperlipidemiaWilliam L Baker
Schools of Pharmacy and Medicine, University of Connecticut, 263 Farmington Ave, MC2205, Storrs and Farmington, CT 06030, USA
Adv Ther 28:13-27. 2011.... - Post-cardiothoracic surgery atrial fibrillation: a review of preventive strategiesWilliam L Baker
School of Pharmacy, University of Connecticut, Hartford, CT, USA
Ann Pharmacother 41:587-98. 2007..To review the available literature addressing preventive strategies of post-cardiothoracic surgery atrial fibrillation (post-CTS atrial fibrillation)... - Cardiovascular effects of migraine therapyWilliam L Baker
Department of Pharmacy Practice, UCONN School of Pharmacy, Hartford, CT 0615, USA
Prog Cardiovasc Nurs 18:151-7,161. 2003 - Sizing a trial to alter the trajectory of health behaviours: methods, parameter estimates, and their applicationDavid M Murray
Division of Epidemiology, School of Public Health, The Ohio State University, B222 Starling Loving Hall, 320 West 10th Street, Columbus, OH 43210, USA
Stat Med 26:2297-316. 2007..We provide estimates for the parameters required for those calculations for a number of adolescent health behaviours. We also show how the estimates can be used to plan a future trial... - A comparison of permutation and mixed-model regression methods for the analysis of simulated data in the context of a group-randomized trialDavid M Murray
Department of Psychology, The University of Memphis, TN 38152 3230, USA
Stat Med 25:375-88. 2006..Binomial group- and member-level errors did not otherwise change the relative performance of the two methods with regard to confounding...