Research Topics
| JULIUS MATTEO GUCCIONESummaryCountry: USA Publications
| Collaborators
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Detail Information
Publications
Mechanism underlying mechanical dysfunction in the border zone of left ventricular aneurysm: a finite element model studyJ M Guccione
Department of Surgery, University of California, San Francisco, USA
Ann Thorac Surg 71:654-62. 2001..The mechanism of this regional dysfunction is poorly understood...
The effect of anteroapical aneurysm plication on end-systolic three-dimensional strain in the sheep: a magnetic resonance imaging tagging studyJulius M Guccione
Department of Surgery, University of California, San Francisco, Calif, USA
J Thorac Cardiovasc Surg 131:579-586.e3. 2006..The primary goal of this study was to quantify the effect of anteroapical aneurysm plication on systolic deformation in noninfarcted adjacent (border zone) and remote left ventricular regions in sheep...
Myosplint decreases wall stress without depressing function in the failing heart: a finite element model studyJulius M Guccione
Department of Surgery, School of Medicine, University of California, and San Francisco Veterans Affairs Medical Center, CA 94121, USA
Ann Thorac Surg 76:1171-80; discussion 1180. 2003..We used a realistic mathematical (finite element) model of the dilated human LV to test the hypothesis that Myosplint decreased regional ventricular fiber stress and improved LV function...
Residual stress produced by ventricular volume reduction surgery has little effect on ventricular function and mechanics: a finite element model studyJ M Guccione
Department of Surgery, University of California, San Francisco, Calif, USA
J Thorac Cardiovasc Surg 122:592-9. 2001....
Magnetic resonance imaging-based finite element stress analysis after linear repair of left ventricular aneurysmJoseph C Walker
Joint Graduate Group in Bioengineering, University of California, San Francisco, Calif, USA
J Thorac Cardiovasc Surg 135:1094-102, 1102.e1-2. 2008..Linear repair of left ventricular aneurysm has been performed with mixed clinical results. By using finite element analysis, this study evaluated the effect of this procedure on end-systolic stress...
Effect of ventricular size and patch stiffness in surgical anterior ventricular restoration: a finite element model studyAlan B C Dang
School of Medicine of the University of California, San Francisco, San Francisco, California, USA
Ann Thorac Surg 79:185-93. 2005..CONCLUSIONS: These simulations support the use of SAVER in dilated hearts without a patch...
Altered left ventricular geometry changes the border zone temporal distribution of stress in an experimental model of left ventricular aneurysm: a finite element model studyPavlos Moustakidis
Department of Surgery, Division of Cardiothoracic Surgery, Washington University, St. Louis, MO, USA
Circulation 106:I168-75. 2002..Correlation of this finding with the corresponding regional blood flow, oxygen consumption, and mechanical systolic performance may help elucidate the mechanism underlying the observed global LV dysfunction...
Left ventricular volume and function after endoventricular patch plasty for dyskinetic anteroapical left ventricular aneurysm in sheepPeng Zhang
Department of Surgery, University of California, San Francisco, Calif, USA
J Thorac Cardiovasc Surg 130:1032-8. 2005..Unlike linear repair, left ventricular volume changes seem stable. The ejection fraction is improved, and left ventricular function (stroke volume and the Starling relationship) is maintained...
Endoventricular patch plasty for dyskinetic anteroapical left ventricular aneurysm increases systolic circumferential shortening in sheepPeng Zhang
Department of Surgery, University of California, San Francisco, Calif, USA
J Thorac Cardiovasc Surg 134:1017-24. 2007..We tested the hypotheses that the Dor procedure increases systolic circumferential shortening and longitudinal shortening in noninfarcted left ventricular regions in sheep...
Akinetic myocardial infarcts must contain contracting myocytes: finite-element model studyAlan B C Dang
Division of Cardiothoracic Surgery, School of Medicine, University of California-San Francisco, and SF Dept. of Veterans' Affairs Medical Center, 4150 Clement St, San Francisco, CA 94121, USA
Am J Physiol Heart Circ Physiol 288:H1844-50. 2005..Without contracting myocytes, C = 250 kPa was necessary to achieve akinesis. If infarct stiffness is <285 times normal, contracting myocytes are required to prevent dyskinetic infarct wall motion...
A computationally efficient formal optimization of regional myocardial contractility in a sheep with left ventricular aneurysmKay Sun
Department of Surgery, University of California, San Francisco, USA
J Biomech Eng 131:111001. 2009..The computation time of less than 5 hours associated with our proposed method for estimating regional myocardial contractility in vivo makes it a potentially very useful clinical tool...
Effect of adjustable passive constraint on the failing left ventricle: a finite-element model studyChoon Sik Jhun
Department of Surgery, University of California, San Francisco, California, USA
Ann Thorac Surg 89:132-7. 2010..This study determined the relationship between constraint, diastolic wall stress, chamber stiffness, and pump function. We tested the hypothesis that passive constraint at 3 mm Hg reduces wall stress with minimal change in pump function...
Dor procedure for dyskinetic anteroapical myocardial infarction fails to improve contractility in the border zoneKay Sun
Department of Surgery, University of California, San Francisco, Calif, USA
J Thorac Cardiovasc Surg 140:233-9, 239.e1-4. 2010..Endoventricular patch plasty (Dor) is used to reduce left ventricular volume after myocardial infarction and subsequent left ventricular remodeling...
First finite element model of the left ventricle with mitral valve: insights into ischemic mitral regurgitationJonathan F Wenk
Department of Surgery, University of California, San Francisco, California, USA
Ann Thorac Surg 89:1546-53. 2010..Left ventricular remodeling after posterobasal myocardial infarction can lead to ischemic mitral regurgitation. This occurs as a consequence of leaflet tethering due to posterior papillary muscle displacement...
Biomechanical perspective on the porcine pulmonary root prior to Ross remodelingPeter B Matthews
Department of Surgery, University of California at San Francisco Medical Center UCSF, 94143 0118, USA
J Heart Valve Dis 18:682-90. 2009..The study aim was to determine differences in regional pulmonary root material properties, and to identify changes in wall stress at both pulmonary and systemic pressure...
