Research Topics
| K C GorsonSummaryCountry: USA Publications
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Publications
Approach to neuromuscular disorders in the intensive care unitKenneth C Gorson
Neuromuscular Service, St Elizabeth s Medical Center, Tufts University School of Medicine, Boston, MA 02135, USA
Neurocrit Care 3:195-212. 2005....
Rituximab treatment in patients with IVIg-dependent immune polyneuropathy: a prospective pilot trialKenneth C Gorson
Department of Neurology, Caritas St Elizabeth s Medical Center, Tufts University School of Medicine, 736 Cambridge Street, Boston, Massachusetts 02135, USA
Muscle Nerve 35:66-9. 2007..There was no improvement in secondary endpoints. No adverse events occurred. In this small prospective study, rituximab did not reduce IVIg requirements in the majority of patients with IVIg-dependent, immune-mediated polyneuropathies...
Chronic inflammatory demyelinating polyneuropathy disease activity status: recommendations for clinical research standards and use in clinical practiceKenneth C Gorson
Department of Neurology, St Elizabeth s Medical Center, Tufts University School of Medicine, Boston, MA 02135, USA
J Peripher Nerv Syst 15:326-33. 2010..0001). The CDAS is considered a simple and reproducible tool to classify patients with CIDP according to disease activity and treatment status that can be applied easily in practice and potentially to select patients for clinical trials...
Acute brachial diplegia due to Lyme diseaseKenneth C Gorson
St Elizabeth s Medical Center, Tufts University School of Medicine Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02135, USA
Neurologist 17:24-7. 2011..to describe acute brachial diplegia as the initial manifestation of Lyme disease...
Non-length dependent small fibre neuropathy/ganglionopathyK C Gorson
Department of Neurology, St Elizabeth s Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02135, USA
J Neurol Neurosurg Psychiatry 79:163-9. 2008..To describe the clinical and laboratory features of a painful non-length dependent, small fibre ganglionopathy (SFG)...
Vasculitic neuropathies: an updateKenneth C Gorson
Tufts University School of Medicine, Boston, Massachusetts, USA
Neurologist 13:12-9. 2007..These conditions are defined pathologically by tissue biopsy demonstrating disruption or destruction of the vessel wall with inflammatory cell infiltrates...
Additional causes for distal sensory polyneuropathy in diabetic patientsK C Gorson
Department of Neurology, St Elizabeth s Medical Center, 736 Cambridge Street, Boston, MA 02135, USA
J Neurol Neurosurg Psychiatry 77:354-8. 2006..To assess the frequency of additional causes of distal sensory polyneuropathy (DSP) in patients with diabetes mellitus (DM)...
Efficacy of mycophenolate mofetil in patients with chronic immune demyelinating polyneuropathyKenneth C Gorson
Division of Neurology, St Elizabeth s Medical Center, Tufts University School of Medicine, Boston, MA 02135, USA
Neurology 63:715-7. 2004..The authors found that MMF induced a modest benefit in ~20% of their patients and stabilized patient condition, allowing reduction of steroid or IVIg therapy...
Treatment experience in patients with anti-myelin-associated glycoprotein neuropathyK C Gorson
Division of Neurology, St Elizabeth s Medical Center, Tufts University School of Medicine, 736 Cambridge Street, Boston, Massachusetts 02135, USA
Muscle Nerve 24:778-86. 2001..There were no clinical or electrodiagnostic features associated with a treatment response, nor did a reduction of the anti-MAG antibody titer correlate with clinical improvement...
Influence of diabetes mellitus on chronic inflammatory demyelinating polyneuropathyK C Gorson
Division of Neurology, St Elizabeth s Medical Center, 736 Cambridge Street, Boston, Massachusetts 02135, USA
Muscle Nerve 23:37-43. 2000..These differences most likely reflect the additive effects of superimposed diabetic axonal polyneuropathy in patients who develop CIDP...
Clinical features, evaluation, and treatment of patients with polyneuropathy associated with monoclonal gammopathy of undetermined significance (MGUS)K C Gorson
Neurology Service, St Elizabeth s Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02135, USA
J Clin Apher 14:149-53. 1999..In addition to plasma exchange, chlorambucil, and cyclophosphamide, interferon-alpha is a novel therapy that holds promise for patients with IgM neuropathies associated with anti-myelin associated antibodies...
Rapid infusion of intravenous immune globulin in patients with neuromuscular disordersJ A Grillo
Division of Neurology, St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, MA 02135, USA
Neurology 57:1699-701. 2001..Fourteen of 17 patients (82%) receiving maintenance therapy preferred rapid IVIg infusion because of its convenience. Rapid-infusion IVIg can be given safely and conveniently in many patients with neuromuscular disorders...
Nonpoliovirus poliomyelitis simulating Guillain-Barré syndromeK C Gorson
Division of Neurology, St Elizabeth s Medical Center, 736 Cambridge St, Boston, MA 02135, USA
Arch Neurol 58:1460-4. 2001....
Intramuscular interferon beta-1a in chronic inflammatory demyelinating polyradiculoneuropathyR A C Hughes
Department of Neurology, St Elizabeth s Medical Center, 736 Cambridge Street, Boston, MA 02135, USA
Neurology 74:651-7. 2010..Because IM interferon beta-1a (IM IFNbeta-1a) is an effective and safe treatment for MS, we conducted a dose-ranging efficacy study of IFNbeta-1a in patients with CIDP...
Successful treatment of dermatomyositis during pregnancy with intravenous immunoglobulin monotherapyLloyd Williams
Tufts University School of Medicine, Boston, MA 02135, USA
Obstet Gynecol 109:561-3. 2007..Corticosteroids are a standard treatment for dermatomyositis in pregnancy, but they have adverse effects. Intravenous immune globulin is an effective therapy for this condition and may have few adverse effects...
Efficacy of intravenous immunoglobulin in patients with IgG monoclonal gammopathy and polyneuropathyKenneth C Gorson
Division of Neurology, St Elizabeth s Medical Center, Tufts University School of Medicine, 736 Cambridge St, Boston, MA 02135, USA
Arch Neurol 59:766-72. 2002..Plasma exchange has been shown to be effective but alternative therapies have not been systematically evaluated...
Influence of critical illness on axonal loss in Guillain-Barré syndromeDoreen Ho
Department of Neurology, St Elizabeth s Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02135, USA
Muscle Nerve 39:10-5. 2009..11), in the ICU (26 vs. 15), and in the hospital (29 vs. 18). Sixty-eight percent of patients with GBS in the ICU developed axon loss, but this was not related to the usual precipitants of CIP...
Vascular endothelial growth factor gene transfer for diabetic polyneuropathy: a randomized, double-blinded trialAllan H Ropper
Department of Neurology, Brigham and Women s Hospital, Boston, MA 02115, USA
Ann Neurol 65:386-93. 2009..Randomized, blinded trial of intramuscular gene transfer using plasmid vascular endothelial growth factor (VEGF) to treat diabetic polyneuropathy...
Positive salivary gland biopsy, Sjögren syndrome, and neuropathy: clinical implicationsKenneth C Gorson
Division of Neurology, St Elizabeth s Medical Center, Tufts University School of Medicine, 736 Cambridge Street, Boston, Massachusetts 02135, USA
Muscle Nerve 28:553-60. 2003..ataxic neuropathy is uncommon; and (4). the lack of sicca symptoms or anti-SSA or SSB antibodies in patients with neuropathy does not exclude Sjögren syndrome based upon salivary gland pathology...
The use of complementary and alternative medicines by patients with peripheral neuropathyBrian Brunelli
Division of Neurology, St Elizabeth s Medical Center, 736 Cambridge Street, Boston, MA 02135, USA
J Neurol Sci 218:59-66. 2004..CAM users were better educated than nonusers, but most did not discuss CAM treatments with their physician. Neuropathic pain was substantially more common in CAM users, and lack of pain control was the most common reason for CAM use...
