W D Funk

Summary

Affiliation: Geron Corporation
Country: USA

Publications

  1. ncbi Telomerase expression restores dermal integrity to in vitro-aged fibroblasts in a reconstituted skin model
    W D Funk
    Geron Corporation, 230 Constitution Drive, Menlo Park, California 94025, USA
    Exp Cell Res 258:270-8. 2000
  2. ncbi Telomerase expression prevents replicative senescence but does not fully reset mRNA expression patterns in Werner syndrome cell strains
    D Choi
    Geron Corporation, Menlo Park, California 94025, USA
    FASEB J 15:1014-20. 2001
  3. ncbi The RNA component of human telomerase
    J Feng
    Geron Corporation, Menlo Park, CA 94025, USA
    Science 269:1236-41. 1995

Collaborators

Detail Information

Publications3

  1. ncbi Telomerase expression restores dermal integrity to in vitro-aged fibroblasts in a reconstituted skin model
    W D Funk
    Geron Corporation, 230 Constitution Drive, Menlo Park, California 94025, USA
    Exp Cell Res 258:270-8. 2000
    ..Thus, telomerase activity not only confers replicative immortality to skin fibroblasts, but can also prevent or reverse the loss of biological function seen in senescent cell populations...
  2. ncbi Telomerase expression prevents replicative senescence but does not fully reset mRNA expression patterns in Werner syndrome cell strains
    D Choi
    Geron Corporation, Menlo Park, California 94025, USA
    FASEB J 15:1014-20. 2001
    ....
  3. ncbi The RNA component of human telomerase
    J Feng
    Geron Corporation, Menlo Park, CA 94025, USA
    Science 269:1236-41. 1995
    ..HeLa cells transfected with an antisense hTR lost telomeric DNA and began to die after 23 to 26 doublings. Thus, human telomerase is a critical enzyme for the long-term proliferation of immortal tumor cells...