Research Topics
Genomes and GenesSpecies | Susanna F GreerSummaryAffiliation: Georgia State University Country: USA Publications
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Detail Information
Publications
Roles for common MLL/COMPASS subunits and the 19S proteasome in regulating CIITA pIV and MHC class II gene expression and promoter methylationOlivia I Koues
Division of Cellular and Molecular Biology and Physiology, Georgia State University, Atlanta, Georgia, USA
Epigenetics Chromatin 3:5. 2010..CONCLUSION: Taken together, these experiments suggest that the 19S proteasome plays a crucial role in the initial reorganization of events enabling the relaxation of the repressive chromatin structure surrounding inducible promoters...
Early epigenetic events regulate the adaptive immune response gene CIITANinad T Mehta
Division of Cellular and Molecular Biology and Physiology, Department of Biology, Georgia State University, Atlanta, GA, USA
Epigenetics 6:516-25. 2011....
The 19S proteasome positively regulates histone methylation at cytokine inducible genesOlivia I Koues
Division of Molecular Genetics and Biochemistry, Department of Biology, Georgia State University, Atlanta, Georgia 30302, USA
Biochim Biophys Acta 1789:691-701. 2009....
Regulation of acetylation at the major histocompatibility complex class II proximal promoter by the 19S proteasomal ATPase Sug1Olivia I Koues
Division of Molecular Genetics and Biochemistry, Department of Biology, Georgia State University, Atlanta, Georgia 30302, USA
Mol Cell Biol 28:5837-50. 2008..Our current study strongly implicates the 19S ATPase Sug1 in modifying histones to initiate MHC-II transcription and provides novel insights into the role of the proteasome in the regulation of mammalian transcription...
The 19S ATPase S6a (S6'/TBP1) regulates the transcription initiation of class II transactivatorAgnieszka D Truax
Division of Cellular and Molecular Biology and Physiology, Department of Biology, College of Arts and Sciences, Georgia State University, Atlanta, GA 30302, USA
J Mol Biol 395:254-69. 2010..These analyses demonstrate the importance of 19S ATPases in the assembly of CIITApIV transcription machinery and provide additional insight into the regulatory mechanisms of the 19S proteasome in mammalian transcription...
Proteolytic and non-proteolytic roles of ubiquitin and the ubiquitin proteasome system in transcriptional regulationKavita P Bhat
Division of Cellular and Molecular Biology and Phsyiclogy, Department of Biology, Georgia State University, Atlanta, GA 30302, USA
Biochim Biophys Acta 1809:150-5. 2011..This article is part of a Special Issue entitled The 26S Proteasome: When degradation is just not enough!..
The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcriptionKavita P Bhat
Division of Cellular and Molecular Biology and Physiology, Department of Biology, Georgia State University, Atlanta, Georgia 30302, Atlanta, GA 30302 4010, USA
Mol Immunol 45:2214-24. 2008..Taken together, these data demonstrate that both 19S and 20S subunits of the 26S proteasome play specific and critical roles in regulating CIITA activity and MHC class II transcription...
ChIP and Re-ChIP assays: investigating interactions between regulatory proteins, histone modifications, and the DNA sequences to which they bindAgnieszka D Truax
Division of Cellular and Molecular Biology and Physiology, Department of Biology, Georgia State University, Atlanta, GA, USA
Methods Mol Biol 809:175-88. 2012..The protocols that follow describe general strategies used to perform ChIP and Re-ChIP assays for the study of specific protein-DNA interactions...
