Research Topics
| H G PreussSummaryAffiliation: Georgetown University Country: USA Publications
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Publications
Protective effects of a novel niacin-bound chromium complex and a grape seed proanthocyanidin extract on advancing age and various aspects of syndrome XHarry G Preuss
Department of Physiology, Georgetown University Medical Center, Washington, D C 20007, USA
Ann N Y Acad Sci 957:250-9. 2002..These natural strategies possess a highly favorable risk/benefit ratio...- Efficacy of a novel calcium/potassium salt of (-)-hydroxycitric acid in weight controlH G Preuss
Department of Physiology and Biophysics, Georgetown University Medical Center, Basic Science Building, Room 231 B, 4000 Reservoir Rd, N W, Washington, DC 20057, USA
Int J Clin Pharmacol Res 25:133-44. 2005..We conclude that dosage levels, timing of administration, subject compliance and bioavailability of HCA-SX significantly affect results and that when taken as directed, HCA-SX is a highly effective adjunct to healthy weight control... - Comparing metabolic effects of six different commercial trivalent chromium compoundsHarry G Preuss
Georgetown University Medical Center, Department of Physiology, Washington, DC 20057, United States
J Inorg Biochem 102:1986-90. 2008..Furthermore, both NBC and picolinate were protective in lessening free radical formation and DNA damage in the liver and kidneys... - Changes in total body bone mineral density following a common bone health plan with two versions of a unique bone health supplement: a comparative effectiveness research studyJoel E Michalek
Integrative Health Technologies, Inc, 4940 Broadway, San Antonio, Texas 78209, USA
Nutr J 10:32. 2011..This study is a response to this call to action... - Lowering the glycemic index of white bread using a white bean extractJay K Udani
Medicus Research LLC, Northridge, CA 91325, USA
Nutr J 8:52. 2009..The objective of this study was to determine whether the addition of Phase 2 would lower the GI of a commercially available high glycemic food (white bread)... - Minimum inhibitory concentrations of herbal essential oils and monolaurin for gram-positive and gram-negative bacteriaHarry G Preuss
Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC 20057, USA
Mol Cell Biochem 272:29-34. 2005.... - Citrus aurantium as a thermogenic, weight-reduction replacement for ephedra: an overviewHarry G Preuss
Department of Physiology, Medicine and Pathology, Georgetown University Medical Center, Washington, DC 20057, USA
J Med 33:247-64. 2002..At present, Citrus aurantium may be the best thermogenic substitute for ephedra. However, more studies are needed to establish this definitively... - Wild garlic has a greater effect than regular garlic on blood pressure and blood chemistries of ratsH G Preuss
Department of Physiology, Georgetown University Medical Center, Washington, DC 20007, USA
Int Urol Nephrol 32:525-30. 2001..In addition, AU decreased total cholesterol significantly and tended to increase HDL compared to AS. Accordingly, the results suggest that AU has a greater therapeutic benefit compared to AS at a given concentration... - Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight lossH G Preuss
Department of Physiology and Biophysics, Georgetown University Medical Center, Georgetown, Washington, DC 20057, USA
Diabetes Obes Metab 6:171-80. 2004..NBC has demonstrated its ability to maintain healthy insulin levels, while GSE has been shown to regulate weight loss and blood sugar levels... - Whole cinnamon and aqueous extracts ameliorate sucrose-induced blood pressure elevations in spontaneously hypertensive ratsHarry G Preuss
Department of Physiology, Georgetown University Medical Center, Washington, DC 20057, USA
J Am Coll Nutr 25:144-50. 2006..Accordingly, the purpose of the present study was to examine the effects of dietary cinnamon on systolic BP (SBP), and various glucose- and insulin-related parameters in spontaneously hypertensive rats (SHR)... - Enhanced insulin-hypoglycemic activity in rats consuming a specific glycoprotein extracted from maitake mushroomHarry G Preuss
Department of Physiology, Georgetown University Medical Center, 231 B Basic Science Building, 4000 Reservoir Rd, NW, Washington, DC 20057, USA
Mol Cell Biochem 306:105-13. 2007.... - Randomized trial of a combination of natural products (cernitin, saw palmetto, B-sitosterol, vitamin E) on symptoms of benign prostatic hyperplasia (BPH)H G Preuss
Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC 20007, USA
Int Urol Nephrol 33:217-25. 2001..The combination of natural products caused no significant adverse side effects... - High dose astaxanthin lowers blood pressure and increases insulin sensitivity in rats: are these effects interdependent?Harry G Preuss
Georgetown University Medical Center, Department of Biochemistry, Washington, DC 20057, USA
Int J Med Sci 8:126-38. 2011..Also, Asta at higher doses lessens restraint stress, whereas, captopril and pioglitazone did not at the doses examined, even though they influenced the BP and glucose-insulin systems respectively... - Maitake mushroom extracts ameliorate progressive hypertension and other chronic metabolic perturbations in aging female ratsHarry G Preuss
Georgetown University Medical Center, Department of Physiology, Washington, DC 20057, USA
Int J Med Sci 7:169-80. 2010.... - Influence of gel and powdered formulations of coenzyme Q10 on metabolic parameters in ratsHarry G Preuss
Department of Physiology, Georgetown University Medical Center, Basic Science Building, Room 231B, 3900 Reservoir Road, N W, Washington, DC 20057, USA
Mol Cell Biochem 340:169-73. 2010..From the data, we conclude that the choice of the formulation containing Co Q10 to be used should be based on the desired healthful benefits... - Bean amylase inhibitor and other carbohydrate absorption blockers: effects on diabesity and general healthHarry G Preuss
Georgetown University Medical Center, Departments of Physiology, Medicine and Pathology, 4000 Reservoir Road, NW, Washington, D C 20057, USA
J Am Coll Nutr 28:266-76. 2009..This paper reviews many aspects of diabesity and the use of "carb blockers" to prevent and ameliorate the situation. In many respects, carb blockers mimic the beneficial effects of fibers... - Niacin-bound chromium increases life span in Zucker Fatty RatsHarry G Preuss
Georgetown University Medical Center, Department of Biochemistry Physiology, Washington, D C 20057, United States
J Inorg Biochem 105:1344-9. 2011..We attribute lack of a similar aging effect in the formula group to either lower dosing of NBC and/or that various ingredients in the formula counteracted the antiaging effect(s) of NBC... - Long-term effects of chromium, grape seed extract, and zinc on various metabolic parameters of ratsH G Preuss
Department of Physiology and Biophysics, Georgetown University Medical School, Washington, DC, USA
Mol Cell Biochem 223:95-102. 2001.... - An overview of the safety and efficacy of a novel, natural(-)-hydroxycitric acid extract (HCA-SX) for weight managementH G Preuss
Department of Physiology, Medicine and Pathology Georgetown University Medical Center, Washington, DC 20057, USA
J Med 35:33-48. 2004..No significant adverse effects were reported. These results demonstrate the safety, bioavailability and efficacy of HCA-SX in weight management... - Effects of oral glucosamine and chondroitin sulfate alone and in combination on the metabolism of SHR and SD ratsB W Echard
Department of Physiology and Biophysics, Georgetown University Medical Center Washington, DC 20007, USA
Mol Cell Biochem 225:85-91. 2001..From the above result, we conclude that glucosamine and chondroitin sulfate given alone or together do not produce insulin resistance or other related perturbations in two rat strains highly sensitive to sugar-induced insulin resistance... - High sucrose diets increase blood pressure of both salt-sensitive and salt-resistant ratsH G Preuss
Department of Medicine, Georgetown University Medical Center, Washington, DC 20007
Am J Hypertens 5:585-91. 1992..However, it is also possible that the high sugar/low protein diet creates in DSS and DSR the situation responsible for salt induction in DSS.(ABSTRACT TRUNCATED AT 250 WORDS).. - Blood pressure responses to sucrose ingestion in four rat strainsH G Preuss
Department of Medicine (Nephrology Division, Georgetown University Medical Center, Washington, DC
Am J Hypertens 5:244-50. 1992.... - Effects of canrenone on RRM-sucrose hypertension in WKYH G Preuss
Department of Medicine Nephrology Division, Georgetown University Medical Center, Washington, D C
Clin Exp Hypertens A 13:917-23. 1991..Therefore, like the RRM-salt model, evidence suggests that the RRM-sucrose model is also caused, at least in part, by a digoxin-like factor (DLF)... - Effects of niacin-bound chromium, Maitake mushroom fraction SX and (-)-hydroxycitric acid on the metabolic syndrome in aged diabetic Zucker fatty ratsNadeem Talpur
Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC 20057, USA
Mol Cell Biochem 252:369-77. 2003..These results demonstrate that elderly diabetics and even aging individuals might benefit from a similar regimen... - Excess sucrose and glucose ingestion acutely elevate blood pressure in spontaneously hypertensive ratsM el Zein
Department of Medicine (Nephrology, Georgetown University Medical Center, Washington, DC 20007
Am J Hypertens 3:380-6. 1990..This is secondary, at least in part, to alterations in NE metabolism... - Long-term effects of excess sucrose ingestion on three strains of ratsM el Zein
Georgetown University Medical Center, Department of Medicine (Nephrology, Washington, D.C. 20007
Am J Hypertens 3:560-2. 1990..Consistent changes in body weights between the rats on the different diets were lacking. We conclude that excess ingestion of sucrose can cause chronic elevations in BP, the pattern of which varies among rat strains... - Antifungal activities of origanum oil against Candida albicansV Manohar
Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC 20007, USA
Mol Cell Biochem 228:111-7. 2001.... - Antihypertensive and metabolic effects of whole Maitake mushroom powder and its fractions in two rat strainsNadeem A Talpur
Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC 20007, USA
Mol Cell Biochem 237:129-36. 2002..We conclude that the examined forms of Maitake mushroom have antihypertensive and antidiabetic potential which differ among rat strains. The ES fraction may decrease SBP in SHR via alteration in the renin-angiotensin system... - Inhibition by natural dietary substances of gastrointestinal absorption of starch and sucrose in rats 2. Subchronic studiesHarry G Preuss
Georgetown University Medical Center, Department of Physiology, Washington, DC 20057, USA
Int J Med Sci 4:209-15. 2007.... - Effects of a water-soluble extract of maitake mushroom on circulating glucose/insulin concentrations in KK miceV Manohar
Department of Physiology, Georgetown University Medical Center, Washington, DC 20007, USA
Diabetes Obes Metab 4:43-8. 2002..The lowering of both circulating glucose and insulin concentrations suggests that FXM works primarily by enhancing peripheral insulin sensitivity... - Effects of Maitake mushroom fractions on blood pressure of Zucker fatty ratsNadeem Talpur
Department of Physiology, Medicine and Pathology, Georgetown University Medical Center, Washington, DC 20057, USA
Res Commun Mol Pathol Pharmacol 112:68-82. 2002..We conclude that fraction SX of Maitake mushroom may be useful to treat insulin resistance alone or combined with other natural products such as bitter melon and niacin-bound chromium... - Hepatoprotective ability of a novel botanical formulation on mild liver injury in rats produced by acute acetaminophen and/or alcohol ingestionB W Echard
Department of Physiology and Biophysics, Georgetown University Medical Center, Washington, DC 20007, USA
Res Commun Mol Pathol Pharmacol 110:73-85. 2001..We conclude that oral ingestion of a novel botanical formulation (a combination of medicinal herbs) is effective in lessening drug-induced hepatotoxicity produced by acetaminophen and/or ethyl alcohol in an animal model... - Effect of sodium and potassium ingestion on renal growth in ratsC Garcia
Department of Medicine (Nephrology, Georgetown University Medical Center, Washington, DC 20007
Am J Hypertens 3:65-8. 1990..Based on RNA, DNA and protein metabolism, the form of growth (hypertrophy or hyperplasia) is also not influenced by renal electrolyte handling... - Influence of a combination of herbs on appetite suppression and weight loss in ratsN A Talpur
Department of Medicine, Renal Division, Georgetown University Medical Center, Washington, DC 20007, USA
Diabetes Obes Metab 3:181-5. 2001..CONCLUSIONS: Data collected on rats suggest that the herbal formulation examined might be a useful and safe combination to overcome the overweight state and obesity... - Presence of a serum vasoconstrictive factor following unilateral nephrectomyM H Razavi
Department of Medicine (Nephrology Division, Georgetown University Medical Center, Washington, D.C. 20007
Am J Hypertens 1:91S-95S. 1988.... - Does renotropin have a role in the pathogenesis of hypertension?H G Preuss
Department of Medicine, Georgetown University Medical Center, Washington, D.C. 20007
Am J Hypertens 2:65-71. 1989.... - Inhibition by natural dietary substances of gastrointestinal absorption of starch and sucrose in rats and pigs: 1. Acute studiesHarry G Preuss
Georgetown University Medical Center, Department of Physiology, Washington, DC 20057, USA
Int J Med Sci 4:196-202. 2007..These results support the hypothesis that the enzyme inhibitors examined here at reasonable doses can safely lower the glycemic loads starch and sucrose... - The rabbit renotropic systemJ Areas
Department of Medicine, Georgetown University Medical Center, Washington, D. C. 20007
Am J Hypertens 1:152-7. 1988..We conclude that the primary rabbit kidney culture assay for renotropin is highly sensitive and will be an important tool to comprehend the role of renotropin in the pathogenesis of hypertension... - Colorimetry of p-aminohippurate in the presence of sulfamethoxazoleH G Preuss
Dept of Medicine Nephrology Division, Georgetown University Medical Center, Washington, DC 20007
Clin Chem 34:422-3. 1988..We found that isoamyl acetate removes sulfamethoxazole from the samples without influencing PAH. The extraction is simple, inexpensive, and reproducible... - Comparison of Saw Palmetto (extract and whole berry) and Cernitin on prostate growth in ratsNadeem Talpur
Department of Physiology, Georgetown University Medical Center, Washington, DC 20007, USA
Mol Cell Biochem 250:21-6. 2003..In conclusion, these studies show the ability of Saw Palmetto (whole berry and extract) and Cernitin to influence prostatic hyperplasia via effects on androgen metabolism... - Overview of resistance training, diet, hormone replacement and nutritional supplements on age-related sarcopenia--a minireviewAlexander D de los Reyes
Department of Physiology, Georgetown University Medical Center, Washington, DC 20057, USA
Res Commun Mol Pathol Pharmacol 113:159-70. 2003.... - A Dietary supplement containing standardized Phaseolus vulgaris extract influences body composition of overweight men and womenLeonardo Celleno
Cosmetic Research Center, dell Università Cattolica di Roma, Rome, Italy
Int J Med Sci 4:45-52. 2007.... - Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extractDebasis Bagchi
Creighton University School of Pharmacy and Allied Health Professions, Omaha, NE 68178, USA
Indian J Exp Biol 40:717-26. 2002.... - Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extractDebasis Bagchi
Department of Pharmacy Sciences, Medical Center, School of Pharmacy and Creighton University Health Professions, 2500 California Plaza, Omaha, NE 68178, USA
Mutat Res 523:87-97. 2003..These results demonstrate that GSPE may serve as a potential therapeutic tool in promoting cardiovascular health via a number of novel mechanisms... - Efficacy of a novel chitosan formulation on fecal fat excretion: a double-blind, crossover, placebo-controlled studyJorge Barroso Aranda
Oasis of Hope Hospital, Tijuana, Baja California, Mexico
J Med 33:209-25. 2002..Using multiple comparisons, it was ascertained that the novel formulation containing chitosan plus psyllium husk seeds increases fecal fat excretion... - Cellular protection with proanthocyanidins derived from grape seedsDebasis Bagchi
Department of Pharmacy Services, Creighton University School of Pharmacy and Allied Health Professions, Omaha, Nebraska 68178, USA
Ann N Y Acad Sci 957:260-70. 2002..These results demonstrate that GSPE is highly bioavailable and may serve as a potential therapeutic tool in protecting multiple target organs from structurally diverse drug- and chemical-induced toxicity... - Evaluating efficacy of a chitosan product using a double-blinded, placebo-controlled protocolGilbert R Kaats
Health and Medical Research Center, 4940 Broadway, Suite 201, San Antonio, TX 78209, USA
J Am Coll Nutr 25:389-94. 2006..To examine the safety and efficacy of a chitosan dietary supplement on body composition under free-living conditions... - Blood pressure lowering effects of niacin-bound chromium(III) (NBC) in sucrose-fed rats: renin-angiotensin systemNicholas V Perricone
Michigan State University College of Human Medicine, East Lansing, MI 48824 136, USA
J Inorg Biochem 102:1541-8. 2008..Other findings suggest that the NO system is important in sucrose-induced BP elevations as well... - Bioefficacy of a novel calcium-potassium salt of (-)-hydroxycitric acidBernard W Downs
InterHealth Research Center, Benicia, CA, USA
Mutat Res 579:149-62. 2005.... - Comparison of acute absorption of chromium(III) supplementsFrancis C Lau
J Trace Elem Med Biol 21:274-5; author reply 275-6. 2007 - Cytotoxicity and oxidative mechanisms of different forms of chromiumDebasis Bagchi
Department of Pharmacy Sciences, Creighton University School of Pharmacy and Health Professions, 2500 California Plaza, Omaha, NE 68178, USA
Toxicology 180:5-22. 2002..The safety of chromium(III) is largely dependent on the ligand, and adequate clinical studies are warranted to demonstrate the safety and efficacy of chromium(III) for human consumption... - Effects of acute and chronic oval exposure of lead on blood pressure and bone mineral density in ratsDebasis Bagchi
Department of Pharmacy Sciences, Creighton University Medical Center, Omaha, NE 68178, USA
J Inorg Biochem 99:1155-64. 2005..Early accumulation of Pb over a short period was also associated with decreased BMD at the end of one year. Chelation after the initial Pb challenge at various times favorably influenced the SBP but could not prevent the lowering of BMD...