Heather B Jaspan

Summary

Affiliation: Fred Hutchinson Cancer Research Center
Country: USA

Publications

  1. ncbi Quantitative competitive reverse transcription polymerase chain reaction is not a useful method for quantification of CD4 and CD8 cell status during HIV infection
    Heather B Jaspan
    Interdisciplinary Program in Molecular and Cellular Biology Tulane University School of Medicine, New Orleans, LA 70112, USA
    J Negat Results Biomed 2:2. 2003
  2. ncbi Amniotic fluid has higher relative levels of lentivirus-specific antibodies than plasma and can contain neutralizing antibodies
    Heather B Jaspan
    Interdisciplinary Program in Molecular and Cellular Biology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA
    J Clin Virol 31:190-7. 2004
  3. ncbi Preventing neonatal HIV: a review
    Heather B Jaspan
    Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70119, USA
    Curr HIV Res 1:321-7. 2003
  4. ncbi Expression of granzyme B mRNA is altered in human immunodeficiency virus infected patients
    Heather B Jaspan
    Molecular and Cellular Biology Program, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA
    Exp Mol Pathol 74:13-6. 2003
  5. ncbi Scientific justification for the participation of children and adolescents in HIV-1 vaccine trials in South Africa
    Heather B Jaspan
    Desmond Tutu HIV Centre, University of Cape Town, South Africa
    S Afr Med J 95:685-7. 2005
  6. ncbi The maturing immune system: implications for development and testing HIV-1 vaccines for children and adolescents
    Heather B Jaspan
    AIDS 20:483-94. 2006
  7. ncbi Adolescent HIV prevalence, sexual risk, and willingness to participate in HIV vaccine trials
    Heather B Jaspan
    Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa
    J Adolesc Health 39:642-8. 2006
  8. ncbi The role of polyclonal intravenous immunoglobulin in treating HIV-infected children with severe bacterial infections: a retrospective cohort study
    Lyen C Huang
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa
    BMC Infect Dis 8:127. 2008

Detail Information

Publications8

  1. ncbi Quantitative competitive reverse transcription polymerase chain reaction is not a useful method for quantification of CD4 and CD8 cell status during HIV infection
    Heather B Jaspan
    Interdisciplinary Program in Molecular and Cellular Biology Tulane University School of Medicine, New Orleans, LA 70112, USA
    J Negat Results Biomed 2:2. 2003
    ..Such a method would also be useful in assessing the immune status of patients retrospectively...
  2. ncbi Amniotic fluid has higher relative levels of lentivirus-specific antibodies than plasma and can contain neutralizing antibodies
    Heather B Jaspan
    Interdisciplinary Program in Molecular and Cellular Biology, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA
    J Clin Virol 31:190-7. 2004
    ..CONCLUSIONS: Active immunity to HIV-1 resulting in virus-specific antibodies in amniotic fluid exists, and may be a natural barrier to in utero infection. This may provide hope for stimulating neutralizing antibody via vaccine design...
  3. ncbi Preventing neonatal HIV: a review
    Heather B Jaspan
    Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, LA 70119, USA
    Curr HIV Res 1:321-7. 2003
    ..However, post-natal transmission via breast milk remains a major challenge. As we continue to find cost-effective answers to protect infants worldwide, the search for a HIV-1 vaccine continues...
  4. ncbi Expression of granzyme B mRNA is altered in human immunodeficiency virus infected patients
    Heather B Jaspan
    Molecular and Cellular Biology Program, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA
    Exp Mol Pathol 74:13-6. 2003
    ..Cell-mediated cytotoxicity during HIV-1 infection may be impaired due to a deficient quantity of active cytotoxic granules or to their abnormal regulation...
  5. ncbi Scientific justification for the participation of children and adolescents in HIV-1 vaccine trials in South Africa
    Heather B Jaspan
    Desmond Tutu HIV Centre, University of Cape Town, South Africa
    S Afr Med J 95:685-7. 2005
  6. ncbi The maturing immune system: implications for development and testing HIV-1 vaccines for children and adolescents
    Heather B Jaspan
    AIDS 20:483-94. 2006
  7. ncbi Adolescent HIV prevalence, sexual risk, and willingness to participate in HIV vaccine trials
    Heather B Jaspan
    Desmond Tutu HIV Centre, University of Cape Town, Cape Town, South Africa
    J Adolesc Health 39:642-8. 2006
    ..To determine human immunodeficiency virus (HIV) prevalence, sexual risk behaviors, and attitudes toward HIV vaccine trials among 11-19 year-olds in a peri-urban community near Cape Town, South Africa...
  8. ncbi The role of polyclonal intravenous immunoglobulin in treating HIV-infected children with severe bacterial infections: a retrospective cohort study
    Lyen C Huang
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa
    BMC Infect Dis 8:127. 2008
    ..We examined the impact of IVIG as an adjuvant therapy in reducing mortality and length of hospital stay in HIV-infected children with serious bacterial infections...