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Genomes and GenesSpecies | Scott DavisSummaryAffiliation: Fred Hutchinson Cancer Research Center Country: USA Publications
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Health risks associated with environmental radiation exposuresScott Davis
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, USA
J Radiol Prot 32:N21-5. 2012..Any new environmental study that is initiated should focus on special circumstances; additional ecological studies are not recommended...
Residential magnetic fields, light-at-night, and nocturnal urinary 6-sulfatoxymelatonin concentration in womenS Davis
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Am J Epidemiol 154:591-600. 2001..These results suggest that exposure to nighttime residential 60-Hz magnetic fields can depress the normal nocturnal rise in melatonin...
Soil ingestion in children and adults in the same familyScott Davis
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
J Expo Sci Environ Epidemiol 16:63-75. 2006..Adult mean soil ingestion rates ranged from 23 to 625 mg/day depending on the tracer, with the highest value based on titanium as a tracer. Soil ingestion rate estimates were more variable in adults than in children...
Childhood leukaemia in Belarus, Russia, and Ukraine following the Chernobyl power station accident: results from an international collaborative population-based case-control studyS Davis
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Int J Epidemiol 35:386-96. 2006..There is little evidence regarding the risk of leukaemia in children following exposure to radionuclides from the Chernobyl Nuclear Power Plant explosion on April 26, 1986...
Thyroid neoplasia, autoimmune thyroiditis, and hypothyroidism in persons exposed to iodine 131 from the hanford nuclear siteScott Davis
Programs in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
JAMA 292:2600-13. 2004..The risk of thyroid disease resulting from prolonged environmental 131I exposure is poorly understood...
Risk of thyroid cancer in the Bryansk Oblast of the Russian Federation after the Chernobyl Power Station accidentScott Davis
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Radiat Res 162:241-8. 2004..These findings are consistent with descriptive reports from contaminated areas of Ukraine and Belarus, and the quantitative estimate of thyroid cancer risk is generally consistent with estimates from other radiation-exposed populations...
Medication use and the risk of breast cancerScott Davis
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center and Department of Epidemiology, University of Washington, Seattle, WA 98109 1024, USA
Eur J Epidemiol 22:319-25. 2007..To investigate whether the use of commonly-prescribed medications, primarily antihypertensives and antidepressants, is associated with an increased risk of breast cancer...
Effects of 60-Hz magnetic field exposure on nocturnal 6-sulfatoxymelatonin, estrogens, luteinizing hormone, and follicle-stimulating hormone in healthy reproductive-age women: results of a crossover trialScott Davis
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Ann Epidemiol 16:622-31. 2006....
Circadian disruption, shift work and the risk of cancer: a summary of the evidence and studies in SeattleScott Davis
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, and Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98109 1024, USA
Cancer Causes Control 17:539-45. 2006..It is anticipated that collectively these studies will enhance our understanding of the role of circadian disruption in the etiology of cancer...
Residential magnetic fields, medication use, and the risk of breast cancerScott Davis
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
Epidemiology 18:266-9. 2007..Exposure to 60-Hz magnetic fields may increase breast cancer risk by suppressing the nocturnal production of melatonin. The use of medications associated with reduced melatonin levels could modify this relationship...
Night shift work, light at night, and risk of breast cancerS Davis
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Natl Cancer Inst 93:1557-62. 2001..This study investigated whether such exposure is associated with an increased risk of breast cancer in women...
Residential magnetic fields and the risk of breast cancerScott Davis
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North MP 474, Seattle, WA 98109 1024, USA
Am J Epidemiol 155:446-54. 2002..These data do not support the hypothesis that exposure to residential magnetic fields is associated with an increased risk of developing breast cancer...
Childhood thyroid cancer, radiation dose from Chernobyl, and dose uncertainties in Bryansk Oblast, Russia: a population-based case-control studyKenneth J Kopecky
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
Radiat Res 166:367-74. 2006....
Timing of menarche and first birth in relation to risk of breast cancer in A-bomb survivorsJean A McDougall
Department of Epidemiology, University of Washington, Health Sciences F 263, Box 357236, Seattle, WA 98195 7236, USA
Cancer Epidemiol Biomarkers Prev 19:1746-54. 2010....
Estimation of thyroid radiation doses for the hanford thyroid disease study: results and implications for statistical power of the epidemiological analysesKenneth J Kopecky
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Health Phys 87:15-32. 2004..The distribution of estimated doses provided the Hanford Thyroid Disease Study with sufficient statistical power to test for dose-response relationships between thyroid outcomes and exposure to Hanford's I...
Age-related variation in the relationship between menopausal hormone therapy and the risk of dying from breast cancerKerryn W Reding
Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, USA
Breast Cancer Res Treat 126:749-61. 2011..07-2.65]). Beyond the influence of EPT use on screening uptake, these data indicate that the improved survival associated with pre-diagnostic EPT use may be due in part to the development of more favorable tumor characteristics...
Thyroid ultrasound abnormalities in persons exposed during childhood to 131I from the Hanford nuclear siteKenneth J Kopecky
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Department of Biostatistics, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98109 1024, USA
Thyroid 15:604-13. 2005..This study does not support the hypothesis that 131I exposure at Hanford's dose levels and dose rates during infancy and childhood increases the prevalence of adult thyroid US abnormalities...
The relationship between multiple myeloma and occupational exposure to six chlorinated solventsLaura S Gold
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Occup Environ Med 68:391-9. 2011..We evaluated associations between multiple myeloma and occupational exposure to six chlorinated solvents: 1,1,1-trichloroethane, trichloroethylene (TCE), methylene chloride (DCM), perchloroethylene, carbon tetrachloride and chloroform...
Occupation and multiple myeloma: an occupation and industry analysisLaura S Gold
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Am J Ind Med 53:768-79. 2010..Multiple myeloma (MM) is an incurable plasma cell malignancy with a poorly understood etiology. The purpose of our research was to examine the relationships between lifetime occupations and MM in a relatively large case-control study...
Locating members of a cohort identified retrospectively from limited data in 50-year-old records: successful approaches employed by the Hanford Thyroid Disease StudyScott Davis
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, M4 B874, PO Box 19024, Seattle, WA 98109 1024, USA
Ann Epidemiol 18:187-95. 2008..Few such studies have been conducted, however, that rely on very old source records, perhaps because of concern that identification and location of a cohort based on very old records would not be feasible...
Incidence of myelodysplastic syndromes within a nonprofit healthcare system in western Washington state, 2005-2006Anneclaire J De Roos
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, Seattle, WA 98109 1024, USA
Am J Hematol 85:765-70. 2010....
Melatonin as a biomarker of circadian dysregulationDana K Mirick
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 A830, P O Box 19024, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 17:3306-13. 2008..Several studies have shown melatonin to be useful in measuring diurnal type, which is of increasing interest as it becomes more apparent that successful adaptation to shift work may be dependent on diurnal preference...
Hyperparathyroidism in persons exposed to iodine-131 from the Hanford Nuclear SiteThomas E Hamilton
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98195, USA
J Clin Endocrinol Metab 90:6545-8. 2005..The risk of primary hyperparathyroidism from exposure to external radiation has been well documented in the last 20 yr. However, it remains unclear whether hyperparathyroidism might also be caused by internal exposure to radioactive iodine...
Testing the circadian gene hypothesis in prostate cancer: a population-based case-control studyYong Zhu
Department of Epidemiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
Cancer Res 69:9315-22. 2009....
Stability of Wertheimer-Leeper wire codes as a measure of exposure to residential magnetic fields over a 9- to 11-year intervalShelley S Tworoger
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
J Expo Anal Environ Epidemiol 12:448-54. 2002..Although the wire code detected less than half of electrical configuration changes, misclassification of exposure over time may change odds ratios and mask possible dose-response relationships...
Shift work, hCLOCK T3111C polymorphism, and endometriosis riskJennifer L Marino
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA, USA
Epidemiology 19:477-84. 2008..One such exposure may be night shift work, which has been associated with menstrual disruption and increased risk of 2 other estrogen-influenced diseases, breast cancer and adverse coronary events...
Antiperspirant use and the risk of breast cancerDana K Mirick
Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
J Natl Cancer Inst 94:1578-80. 2002..9 and P =.40; for deodorant, OR = 1.2 and P =.16). These findings do not support the hypothesis that antiperspirant use increases the risk for breast cancer...
Migraine in postmenopausal women and the risk of invasive breast cancerRobert W Mathes
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 17:3116-22. 2008..Given the strong relationship between endogenous estrogen levels and breast cancer risk, migraine sufferers may experience a reduced risk of breast cancer...
Microarray comparative genomic hybridization reveals genome-wide patterns of DNA gains and losses in post-Chernobyl thyroid cancerRobert R Kimmel
Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Radiat Res 166:519-31. 2006..2, 16q21-q12.2, 17q25.1, 19p13.31-qter, 22q11.21 and 22q13.2. Copy number changes, particularly gains, in post-Chernobyl thyroid cancer are influenced by radiation exposure and age at exposure, in addition to the neoplastic process...
Thyrotropin levels in a population with no clinical, autoantibody, or ultrasonographic evidence of thyroid disease: implications for the diagnosis of subclinical hypothyroidismThomas E Hamilton
Program in Epidermology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
J Clin Endocrinol Metab 93:1224-30. 2008..The current debate regarding whether to decrease the upper limit for the TSH reference range to 2.5 microIU/ml has considerable potential impact on the diagnosis and treatment of subclinical hypothyroidism worldwide...
Do cases and controls matched on the first eight digits of their telephone number share geographic proximity and socioeconomic characteristics?Lynda F Voigt
Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Ann Epidemiol 16:299-304. 2006..The aim of this study is to assess the geographic proximity of cases and controls who share the same "stem" of their telephone number (area code, prefix, and next two digits) and compare their socioeconomic characteristics...
Spatial clustering of myelodysplastic syndromes (MDS) in the Seattle-Puget Sound region of Washington StateMichelle E Ross
Department of Biostatistics, University of Washington, Seattle, WA, USA
Cancer Causes Control 21:829-38. 2010..In this investigation, we described small-scale incidence patterns of MDS within the Seattle-Puget Sound region from 2002 to 2006 and identified potential spatial clusters to inform planning of future studies of MDS etiology...
Relationship between radiation exposure and risk of second primary cancers among atomic bomb survivorsChristopher I Li
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Departments of Epidemiology and Biostatistics, University of Washington, Seattle, WA 98109 1024, USA
Cancer Res 70:7187-98. 2010..Radiation is a potent carcinogen and those with substantial exposures who are diagnosed with a first primary cancer should be carefully screened for second primary cancers, particularly for cancers that are radiation-sensitive...
Associations of common variants in genes involved in metabolism and response to exogenous chemicals with risk of multiple myelomaLaura S Gold
Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Cancer Epidemiol 33:276-80. 2009....
Night shift work and hormone levels in womenScott Davis
Corresponding Author Dana K Mirick, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 A830, P O Box 19024, Seattle, WA 98109
Cancer Epidemiol Biomarkers Prev 21:609-18. 2012..We investigated whether night shift work is associated with decreased levels of urinary 6-sulfatoxymelatonin, the primary metabolite of melatonin, and increased urinary reproductive hormone levels...
Risk of subsequent breast cancer in relation to characteristics of screening mammograms from women less than 50 years of ageDavid B Thomas
Program in Epidemiology, The Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Cancer Epidemiol Biomarkers Prev 11:565-71. 2002..Women <50 years of age with class 1 or 2 calcifications or mammographically dense breasts, or both, should receive high priority for further evaluation and regular breast cancer screening...
Trends in childhood leukemia in Basrah, Iraq, 1993-2007Amy Hagopian
Department of Global Health, School of Public Health, University of Washington, 4534 11th Avenue NE, Seattle, WA 98105, USA
Am J Public Health 100:1081-7. 2010..Through a sister-university relationship between the University of Basrah and the University of Washington, we analyzed Ibn Ghazwan Hospital's leukemia registry data to evaluate trends in childhood leukemia since 1993...
Sleep outcomes in children with hemifacial microsomia and controls: a follow-up studyYona K Cloonan
Department of Epidemiology, Michigan State University, East Lansing, Michigan 48823, USA
Pediatrics 124:e313-21. 2009..Nevertheless, most children with HFM are not referred for sleep studies. We hypothesized that sleep outcomes would be worse in children with HFM versus control subjects...
Residential proximity to industrial facilities and risk of non-Hodgkin lymphomaA J De Roos
Fred Hutchinson Cancer Research Center and the University of Washington Department of Epidemiology, 1100 Fairview Avenue North, M4 B874, Seattle, WA 98109 1024, USA
Environ Res 110:70-8. 2010..However, future studies designed to include greater numbers of persons living near specific types of industries, along with fate-transport modeling of chemical releases, would be informative...
Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the Cardiovascular Health StudyCara L Carty
Department of Epidemiology, University of Washington, WA, USA
J Atheroscler Thromb 16:419-30. 2009..Interaction of the SAA genes with genetic variants of their regulators, IL-1, IL-6 and TNF-alpha in influencing CVD was also explored...
A population-based study of survival in patients with secondary myelodysplastic syndromes (MDS): impact of type and treatment of primary cancersAnneclaire J De Roos
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Department of Epidemiology, University of Washington, Seattle, WA 98109 1024, USA
Cancer Causes Control 18:1199-208. 2007..Clinical observations suggest a worse prognosis for secondary than for primary MDS, but differences in survival have not been studied in a general population sample...
Persistent organochlorine chemicals in plasma and risk of non-Hodgkin's lymphomaAnneclaire J De Roos
Fred Hutchinson Cancer Research Center and University of Washington Department of Epidemiology, Seattle, Washington 98109 1024, USA
Cancer Res 65:11214-26. 2005..02-1.79). Our results add to existing literature, which suggests that exposure to organochlorines contributes to non-Hodgkin's lymphoma risk; these risks were most apparent for certain PCBs and furans...
Implementation of the Women's Health Initiative study designGarnet L Anderson
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA
Ann Epidemiol 13:S5-17. 2003
Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph ConsortiumNathaniel Rothman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Lancet Oncol 7:27-38. 2006..We aimed to test this hypothesis using previously unpublished data from eight European, Canadian, and US case-control studies of the International Lymphoma Epidemiology Consortium (InterLymph)...
Dietary flavonoid intake and non-Hodgkin lymphoma riskCara L Frankenfeld
Division of Cancer, Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
Am J Clin Nutr 87:1439-45. 2008..Dietary flavonoids are polyphenolic compounds proposed to be anticarcinogenic. Flavonoids are well-characterized antioxidants and metal chelators, and certain flavonoids exhibit antiproliferative and antiestrogenic effects...
Blood transfusion, anesthesia, surgery and risk of non-Hodgkin lymphoma in a population-based case-control studyJames R Cerhan
Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 5905, USA
Int J Cancer 123:888-94. 2008..Multiple surgical procedures and/or repeated administration of anesthesia have not been previously reported to be associated with risk of NHL and these exposures warrant further evaluation...
ret/PTC activation is not associated with individual radiation dose estimates in a pilot study of neoplastic thyroid nodules arising in Russian children and adults exposed to Chernobyl falloutR Michael Tuttle
Endocrinology Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
Thyroid 18:839-46. 2008....
Immune-related conditions and immune-modulating medications as risk factors for non-Hodgkin's lymphoma: a case-control studyEric A Engels
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20852, USA
Am J Epidemiol 162:1153-61. 2005..02), but dermatomyositis was absent in cases themselves. Family history of remaining conditions was unrelated to NHL. Results suggest that disordered immunity in some immune-related conditions can lead to NHL...
Anthropometrics, physical activity, related medical conditions, and the risk of non-hodgkin lymphomaJames R Cerhan
Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Cancer Causes Control 16:1203-14. 2005..Physical inactivity increases the risk of obesity and of type 2 diabetes, but there are few data on the association of physical activity with risk of NHL...
Meat and meat-mutagen intake and risk of non-Hodgkin lymphoma: results from a NCI-SEER case-control studyAmanda J Cross
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20892, USA
Carcinogenesis 27:293-7. 2006..39 (0.22-0.70); P trend = 0.004]. Overall, our study suggests that consumption of meat, whether or not it is well-done, does not increase the risk of NHL. Furthermore, neither HCAs nor B[a]P from meat increase the risk of NHL...
Alcohol consumption and risk of non-Hodgkin lymphoma: a pooled analysisLindsay M Morton
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
Lancet Oncol 6:469-76. 2005..Further study designs are needed to determine whether confounding lifestyle factors or immunomodulatory effects of alcohol explain this association...
Organochlorines in carpet dust and non-Hodgkin lymphomaJoanne S Colt
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
Epidemiology 16:516-25. 2005..The incidence of non-Hodgkin lymphoma (NHL) has risen over the past several decades. Reasons for this increase are largely unexplained...
Residential herbicide use and risk of non-Hodgkin lymphomaPatricia Hartge
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland
Cancer Epidemiol Biomarkers Prev 14:934-7. 2005..Environmental exposure to herbicides has been hypothesized to contribute to the long-term increase in non-Hodgkin lymphoma (NHL)...
Cigarette smoking and risk of non-Hodgkin lymphoma: a pooled analysis from the International Lymphoma Epidemiology Consortium (interlymph)Lindsay M Morton
Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, Conneticut, USA
Cancer Epidemiol Biomarkers Prev 14:925-33. 2005....
Epidemiologic evaluation of measurement data in the presence of detection limitsJay H Lubin
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Environ Health Perspect 112:1691-6. 2004..We illustrate various approaches using measurements of pesticide residues in carpet dust in control subjects from a case-control study of non-Hodgkin lymphoma...
Case-control study of simian virus 40 and non-Hodgkin lymphoma in the United StatesEric A Engels
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, 6120 Executive Blvd, EPS 8010, Rockville, MD 20892, USA
J Natl Cancer Inst 96:1368-74. 2004..S. non-Hodgkin lymphoma (NHL) patients. SV40 accidentally contaminated U.S. poliovirus vaccines that were widely administered from 1955 through 1962. However, epidemiologic data linking SV40 with NHL are lacking...
Risk of non-Hodgkin's lymphoma and family history of lymphatic, hematologic, and other cancersNilanjan Chatterjee
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 13:1415-21. 2004..An elevated risk of developing non-Hodgkin's lymphoma (NHL) has been associated with a family history of NHL and several other malignancies, but the magnitude of risks and mechanisms are uncertain...
Hepatitis C virus infection and non-Hodgkin lymphoma: results of the NCI-SEER multi-center case-control studyEric A Engels
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
Int J Cancer 111:76-80. 2004..Our study demonstrates an association between HCV infection and NHL in the United States. HCV infection may be a cause of NHL...
Comparison of pesticide levels in carpet dust and self-reported pest treatment practices in four US sitesJoanne S Colt
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH DHHS, 6120 Executive Boulevard, Room 8112, Rockville, MD 20852, USA
J Expo Anal Environ Epidemiol 14:74-83. 2004..Dust sampling provides an objective measure of specific compounds to which a person may have been exposed through personal use of a pesticide or by drift-in or track-in from outside, and avoids recall bias...
Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: a pooled analysis within the InterLymph ConsortiumKarin Ekstrom Smedby
Department of Medicine, Clinical Epidemiology Unit, Karolinska University Hospital, SE 171 76 Stockholm, Sweden
Blood 111:4029-38. 2008..Thus, specific autoimmune disorders are associated with NHL risk beyond the development of rare NHL subtypes in affected organs. The pattern of associations with NHL subtypes may harbor clues to lymphomagenesis...
Residential insecticide use and risk of non-Hodgkin's lymphomaJoanne S Colt
Occupational and Environmental Epidemiology Branch, Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, Maryland 20852, USA
Cancer Epidemiol Biomarkers Prev 15:251-7. 2006..We concluded that chlordane treatment of homes for termites may increase residents' NHL risk...
Cyclin D1 splice variant and risk for non-Hodgkin lymphomaSophia S Wang
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, EPS MSC 7234, Bethesda, Rockville, MD 20892 7234, USA
Hum Genet 120:297-300. 2006..4, 95% CI = 1.1-1.8, P-trend = 0.021), which was consistent for four B-cell subtypes. As CCND1 expression indicates poor NHL prognosis, our results, if true, would support its potentially dual importance in NHL etiology and survival...
Common genetic variants in proinflammatory and other immunoregulatory genes and risk for non-Hodgkin lymphomaSophia S Wang
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20892 7234, USA
Cancer Res 66:9771-80. 2006..Our results require replication but potentially provide important clues for investigating common genetic variants as susceptibility factors and in disease outcomes, treatment responses, and immunotherapy targets...
Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control studyUnhee Lim
Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Rockville, MD 20852, USA
Blood 109:3050-9. 2007..13; 95% CI = 0.04-0.39), and MTRR Ex5+136T>CTT (OR = 0.67; 95% CI = 0.47-0.97) genotypes. Warranting replication, our finding of gene-nutrient interactions in one-carbon metabolism supports their etiologic involvement in lymphomagenesis...
Family history of hematopoietic malignancies and risk of non-Hodgkin lymphoma (NHL): a pooled analysis of 10 211 cases and 11 905 controls from the International Lymphoma Epidemiology Consortium (InterLymph)Sophia S Wang
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
Blood 109:3479-88. 2007..0; 95% CI = 1.6-5.6). The pattern of NHL heritability appeared to be uniform across NHL subtypes, but risk patterns differed by specific hematopoietic malignancies and the sex of the relative, revealing critical clues to disease etiology...
Vegetables, fruit, and antioxidant-related nutrients and risk of non-Hodgkin lymphoma: a National Cancer Institute-Surveillance, Epidemiology, and End Results population-based case-control studyLinda E Kelemen
Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Am J Clin Nutr 83:1401-10. 2006..91; P for trend = 0.02). An effect modification by exercise and NHL subtype was observed with some food groups and nutrients. CONCLUSION: Higher intakes of vegetables, lutein and zeaxanthin, and zinc are associated with a lower NHL risk...
Hobbies with solvent exposure and risk of non-Hodgkin lymphomaJoanne S Colt
Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Cancer Causes Control 18:385-90. 2007..We conclude that participation in hobbies involving exposure to organic solvents is unlikely to increase NHL risk...
Genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2) and risk of non-Hodgkin lymphomaLindsay M Morton
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
Pharmacogenet Genomics 16:537-45. 2006..15-5.20, P = 0.02). Our data provide evidence that NAT1 and NAT2 genotypes are associated with NHL risk and support a contributory role for carcinogenic aromatic and/or heterocyclic amines in the multi-factorial etiology of NHL...
Cancer consequences of the Chernobyl accident: 20 years onElisabeth Cardis
International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
J Radiol Prot 26:127-40. 2006....
Vegetables- and antioxidant-related nutrients, genetic susceptibility, and non-Hodgkin lymphoma riskLinda E Kelemen
Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN, 55905, USA
Cancer Causes Control 19:491-503. 2008..Although most associations have not been examined previously with NHL, our results suggest the examined polymorphisms are not modifiers of the association between vegetable and zinc intakes and NHL risk...
Immune mechanisms in non-Hodgkin lymphoma: joint effects of the TNF G308A and IL10 T3575A polymorphisms with non-Hodgkin lymphoma risk factorsSophia S Wang
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20892 7234, USA
Cancer Res 67:5042-54. 2007....
Sun exposure, vitamin D receptor gene polymorphisms and risk of non-Hodgkin lymphomaMark P Purdue
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8009, Rockville, MD 20892, USA
Cancer Causes Control 18:989-99. 2007....
Polymorphisms in oxidative stress genes and risk for non-Hodgkin lymphomaSophia S Wang
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA
Carcinogenesis 27:1828-34. 2006....
Non-Hodgkin lymphoma and obesity: a pooled analysis from the InterLymph ConsortiumEleanor V Willett
Epidemiology and Genetics Unit, Department of Health Sciences, University of York, Heslington, York YO10 5DD, United Kingdom
Int J Cancer 122:2062-70. 2008....
Ultraviolet radiation, dietary vitamin D, and risk of non-Hodgkin lymphoma (United States)Patricia Hartge
Division of Cancer Epidemiology and Genetics, National Cancer Institue, Rockville, MD 20852, USA
Cancer Causes Control 17:1045-52. 2006....
Effect of a nighttime magnetic field exposure on sleep patterns in young womenShelley S Tworoger
Channing Laboratory, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02115, USA
Am J Epidemiol 160:224-9. 2004..The intervention magnetic field had no effect on sleep patterns, suggesting that this exposure may not be an important factor in predicting sleep of young women who sleep at home...
Risk of non-Hodgkin lymphoma (NHL) in relation to germline variation in DNA repair and related genesDeirdre A Hill
Cancer Center and Department of Internal Medicine, UNM School of Medicine, 1 University of New Mexico, MSC 10 5550, Albuquerque, NM 87131 0001, USA
Blood 108:3161-7. 2006..03) in the nonhomologous end joining (NHEJ)/V(D)J pathway. These NHEJ/V(D)J-related gene variants represent promising candidates for further studies of NHL etiology and require replication in other studies...
Antibody responses to simian virus 40 T antigen: a case-control study of non-Hodgkin lymphomaEric A Engels
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, 6120 Executive Boulevard, EPS 8010, Rockville, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 14:521-4. 2005..We found no association between the presence of T antibody and NHL, arguing against SV40 as a cause of NHL. Infrequent and low-level T antibody responses among humans could represent cross-reactivity to BK virus T antigen...
Hair dye use, genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphomaLindsay M Morton
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
Carcinogenesis 28:1759-64. 2007..Several previous studies have found non-Hodgkin lymphoma (NHL) risk to be associated with hair dye use, particularly use of permanent, dark colors and use before 1980, when hair dye formulations changed...
A method for cross-species gene expression analysis with high-density oligonucleotide arraysWan Ji
ViaGen Inc, 12357 A Riata Trace Parkway, Suite 100, Austin, TX 78727, USA
Nucleic Acids Res 32:e93. 2004..In addition, we validated cross-species hybridization results by quantitative PCR using randomly selected genes. The method shown herein could be applied to both plant and animal research...
Antibodies to JC and BK viruses among persons with non-Hodgkin lymphomaEric A Engels
Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20892, USA
Int J Cancer 117:1013-9. 2005..Additional research is needed to determine whether JCV replication is decreased in individuals with NHL and whether these findings are consistent with an etiologic role for JCV in NHL...
Prognostic significance of host immune gene polymorphisms in follicular lymphoma survivalJames R Cerhan
Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Blood 109:5439-46. 2007..Common variation in host immune genes warrants further evaluation as a promising class of prognostic factors in follicular lymphoma...
Research Grants
- Breast Cancer Risk and Molecular Change After ChernobylScott Davis; Fiscal Year: 2010....
- Breast Cancer Risk and Molecular Change After ChernobylScott Davis; Fiscal Year: 2009....
- Night Shift Work and Hormone Levels in MenScott Davis; Fiscal Year: 2009..Results will provide important new information regarding the underlying biological basis of the emerging evidence linking night shift work with cancer risk. ..
- Breast Cancer Risk and Molecular Change After ChernobylScott Davis; Fiscal Year: 2007....
- Night Shift Work and Hormone Levels in MenScott Davis; Fiscal Year: 2007..Results will provide important new information regarding the underlying biological basis of the emerging evidence linking night shift work with cancer risk. ..
- NIGHT SHIFT WORKERS AND HORMONE LEVELS IN WOMENScott Davis; Fiscal Year: 2006..Urine samples will be assayed for the primary urinary metabolite of melatonin, 6-sulphatoxymelatonin, and levels of LH, FSH, and estradiol. ..
- Molecular Change and Thyroid Cancer Risk After ChernobylScott Davis; Fiscal Year: 2006..g. recurrence) and individual thyroid radiation dose, patient characteristics, and molecular markers of genetic change. ..
- Night Shift Work and Hormone Levels in MenScott Davis; Fiscal Year: 2010..Results will provide important new information regarding the underlying biological basis of the emerging evidence linking night shift work with cancer risk. ..
