Research Topics | M PrabhakaranSummaryAffiliation: Florida International University Country: USA Publications
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Publications
Molecular modeling studies of surface decoration of hemoglobin by maleimide PEGM Prabhakaran
Department of Biomedical Engineering, Florida International University, Miami, Florida 33174, USA
Artif Cells Blood Substit Immobil Biotechnol 34:381-93. 2006..The modeling shows the adequate surface coverage of the protein hemoglobin with six copies of PEG-5K chains and also exhibits more surface coverage of the hemoglobin as compared to that afforded by two copies of PEG-20K chains...
Large scale motions in a biosensor protein glucose oxidase: a combined approach by QENS, normal mode analysis, and molecular dynamics studiesSujit S Tatke
Biomedical Engineering Department, FL International University, Miami, FL, USA
Biopolymers 89:582-94. 2008..The frequency of vibration calculated from the three methods is used to derive the large scale motions. Theses studies were used to predict the suitable lysine residues for linkage with carbon nanotubes...
Site-specific PEGylation of hemoglobin at Cys-93(beta): correlation between the colligative properties of the PEGylated protein and the length of the conjugated PEG chainB N Manjula
Albert Einstein College of Medicine, Bronx, New York 10461, USA
Bioconjug Chem 14:464-72. 2003..Thus, the biochemically homogeneous PEGylated Hbs described in the present study, surface-decorated with PEG chains of appropriate size, could serve as potential candidates for Hb-based oxygen carriers...
