Research Topics
| Lawrence PhillipsSummaryAffiliation: Emory University Country: USA Publications
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Publications
Once- and twice-daily dosing with rosiglitazone improves glycemic control in patients with type 2 diabetesL S Phillips
Division of Endocrinology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Diabetes Care 24:308-15. 2001..To determine the efficacy of rosiglitazone compared with placebo in reducing hyperglycemia...- An endocrinologist-supported intervention aimed at providers improves diabetes management in a primary care site: improving primary care of African Americans with diabetes (IPCAAD) 7Lawrence S Phillips
Division of Endocrinology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA
Diabetes Care 28:2352-60. 2005..We asked whether interventions targeting clinical inertia can improve outcomes... - Glucose challenge test screening for prediabetes and undiagnosed diabetesL S Phillips
Division of Endocrinology and Metabolism, Emory University School of Medicine, 101 Woodruff Circle, WMRB Room 1027, Atlanta, GA 30322, USA
Diabetologia 52:1798-807. 2009..e. a 50 g oral glucose challenge test (GCT) performed at any time of day, regardless of meal status, with one 1 h sample... - All pre-diabetes is not the same: metabolic and vascular risks of impaired fasting glucose at 100 versus 110 mg/dl: the Screening for Impaired Glucose Tolerance study 1 (SIGT 1)Lawrence S Phillips
Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Emory University Hospital, 1364 Clifton Road, Atlanta, GA 30322, USA
Diabetes Care 29:1405-7. 2006 - The Improving Primary Care of African Americans with Diabetes (IPCAAD) project: rationale and designLawrence S Phillips
Division of Endocrinology, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Control Clin Trials 23:554-69. 2002..We will compare two readily generalizable program interventions that should delineate approaches effective in a primary care setting as needed to improve care and prevent complications in urban African Americans with type 2 diabetes... - Clinical inertiaL S Phillips
Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
Ann Intern Med 135:825-34. 2001..Physicians will need to build into their practice a system of reminders and performance feedback to ensure necessary care... - Postmenopausal hormone therapy: critical reappraisal and a unified hypothesisLawrence S Phillips
General Clinical Research Center, Emory University Hospital, Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Fertil Steril 83:558-66. 2005.... - Diabetes management by residents in training in a municipal hospital primary care site (IPCAAD 2)Christopher D Miller
Divisions of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
Ethn Dis 15:649-55. 2005.... - Association of younger age with poor glycemic control and obesity in urban african americans with type 2 diabetesImad M El-Kebbi
Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
Arch Intern Med 163:69-75. 2003..001). CONCLUSION: Our data show a high prevalence of obesity and poor glycemic control in young adult urban African Americans with diabetes... - Random plasma glucose in serendipitous screening for glucose intolerance: screening for impaired glucose tolerance study 2David C Ziemer
Division of Endocrinology and Metabolism, Emory University School of Medicine, Atlanta, GA, USA
J Gen Intern Med 23:528-35. 2008..With positive results from diabetes prevention studies, there is interest in convenient ways to incorporate screening for glucose intolerance into routine care and to limit the need for fasting diagnostic tests... - Glucose-independent, black-white differences in hemoglobin A1c levels: a cross-sectional analysis of 2 studiesDavid C Ziemer
Division of Endocrinology, Emory University School of Medicine, 49 Jesse Hill Jr Drive SE, Atlanta, GA 30303, USA
Ann Intern Med 152:770-7. 2010..A previous study of participants with prediabetes found that hemoglobin A(1c) (HbA(1c)) levels differed between black and white participants with no differences in glucose concentration... - Rapid A1c availability improves clinical decision-making in an urban primary care clinicChristopher D Miller
Emory University School of Medicine, Atlanta, Georgia 30303, USA
Diabetes Care 26:1158-63. 2003..1 to 8.0%, P = 0.31). CONCLUSIONS: Availability of rapid A1c measurements increased the frequency of intensification of therapy and lowered A1c levels in patients with type 2 diabetes in an urban neighborhood health center... - Diabetes: update on management and treatmentLawrence S Phillips
Division of Endocrinology and Metabolism, Emory University School of Medicine, USA
Ethn Dis 13:S3-32-3. 2003 - The impact of outpatient diabetes management on serum lipids in urban African-Americans with type 2 diabetesDiane M Erdman
Grady Health System Atlanta, Emory University School of Medicine, Atlanta, Georgia 30303, USA
Diabetes Care 25:9-15. 2002.... - Use of a glucose algorithm to direct diabetes therapy improves A1C outcomes and defines an approach to assess provider behaviorChristopher D Miller
Division of Endocrinology, Emory University, 100 Woodruff Circle, Room 1027, Atlanta, GA 30322, USA
Diabetes Educ 32:533-45. 2006.... - Diabetes care in black and white veterans in the southeastern U.SJennifer G Twombly
Division of Endocrinology and Metabolism, Emory University School of Medicine, Atlanta, Georgia, USA
Diabetes Care 33:958-63. 2010..We investigated whether there were differences in diabetes care in the Veterans Administration (VA), where health care access should be relatively uniform... - Age, BMI, and race are less important than random plasma glucose in identifying risk of glucose intolerance: the Screening for Impaired Glucose Tolerance Study (SIGT 5)David C Ziemer
Division of Endocrinology and Metabolism, Emory University, Atlanta, Georgia 30322, USA
Diabetes Care 31:884-6. 2008.... - The "metabolic syndrome" is less useful than random plasma glucose to screen for glucose intoleranceEman A El Bassuoni
Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Prim Care Diabetes 2:147-53. 2008..To compare the utility of metabolic syndrome (MetS) to random plasma glucose (RPG) in identifying people with diabetes or prediabetes... - An intervention to overcome clinical inertia and improve diabetes mellitus control in a primary care setting: Improving Primary Care of African Americans with Diabetes (IPCAAD) 8David C Ziemer
Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine and Grady Health Systems, Atlanta, GA 30322, USA
Arch Intern Med 166:507-13. 2006..Similar approaches may aid health care provider behavior and improve diabetes outcomes in other primary care settings... - A simple meal plan emphasizing healthy food choices is as effective as an exchange-based meal plan for urban African Americans with type 2 diabetesDavid C Ziemer
Division of Endocrinology and Metabolism, Emory University School of Medicine, Atlanta, Georgia 30303, USA
Diabetes Care 26:1719-24. 2003..To compare a simple meal plan emphasizing healthy food choices with a traditional exchange-based meal plan in reducing HbA(1c) levels in urban African Americans with type 2 diabetes... - Many Americans have pre-diabetes and should be considered for metformin therapyMary K Rhee
Department of Medicine, Division of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, Georgia, USA
Diabetes Care 33:49-54. 2010..To determine the proportion of the American population who would merit metformin treatment, according to recent American Diabetes Association (ADA) consensus panel recommendations to prevent or delay the development of diabetes... - Intravenous intralipid-induced blood pressure elevation and endothelial dysfunction in obese African-Americans with type 2 diabetesGuillermo E Umpierrez
Department of Medicine, General Clinical Research Center, Emory University School of Medicine, 49 Jesse Hill Jr Drive, Atlanta, Georgia 30303, USA
J Clin Endocrinol Metab 94:609-14. 2009..We evaluated the effect of sustained elevations of FFA on blood pressure, endothelial function, insulin secretion, inflammatory markers, and renin-angiotensin system... - Diabetes management in urban African Americans: review of a public hospital experienceDavid C Ziemer
Department of Endocrinology, Emory University School of Medicine, Atlanta, Georgia, USA
Ethn Dis 18:336-41. 2008..To review characteristics of an urban (primarily African American) diabetes patient population and discuss experience with treatment strategies, we summarize key retrospective and prospective analyses conducted during 15 years... - Use of a uniform treatment algorithm abolishes racial disparities in glycemic controlMary K Rhee
Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
Diabetes Educ 34:655-63. 2008..The purpose of this study is to compare glycemic control between blacks and whites in a setting where patient and provider behavior is assessed, and where a uniform treatment algorithm is used to guide care... - Screening for diabetes and pre-diabetes with proposed A1C-based diagnostic criteriaDarin E Olson
Atlanta VA Medical Center, Decatur, Georgia, USA
Diabetes Care 33:2184-9. 2010..We hypothesized that screening for diabetes and pre-diabetes with A1C measurements would differ from using oral glucose tolerance tests (OGTT)... - Limited health care access impairs glycemic control in low income urban African Americans with type 2 diabetesMary K Rhee
Emory University School of Medicine, Atlanta, Georgia, USA
J Health Care Poor Underserved 16:734-46. 2005..08%; p=0.009). Policy decisions for improving diabetes outcomes should target barriers to health care access and focus on developing programs to help high-risk populations maintain a regular place of health care... - Screening adults for pre-diabetes and diabetes may be cost-savingRanee Chatterjee
Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
Diabetes Care 33:1484-90. 2010..Early detection would allow management to prevent or delay development of diabetes and diabetes-related complications. We investigated the economic justification for screening for pre-diabetes/diabetes... - Disturbed glucose metabolism among patients taking olanzapine and typical antipsychoticsBoadie W Dunlop
Mood and Anxiety Disorders Program, Department of Psychiatry, Emory University School of Medicine, Atlanta, GA 30329, USA
Psychopharmacol Bull 37:99-117. 2003.... - Clinical inertia contributes to poor diabetes control in a primary care settingDavid C Ziemer
Division of Endocrinology, Department of Medicine, Emory University School of Medicine, Grady Health Systems, Atlanta, GA, USA
Diabetes Educ 31:564-71. 2005..To improve diabetes management and glycemic control nationwide, physicians in training and generalists must learn to overcome clinical inertia, to intensify therapy when appropriate, and to use insulin when clinically indicated... - Utility of casual postprandial glucose levels in type 2 diabetes managementImad M El-Kebbi
Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30303, USA
Diabetes Care 27:335-9. 2004.... - Patient adherence improves glycemic controlMary K Rhee
Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30303, USA
Diabetes Educ 31:240-50. 2005..The purpose of this study was to assess the influence of appointment keeping and medication adherence on HbA1c... - Dual mechanism for type-2 diabetes resolution after Roux-en-Y gastric bypassEdward Lin
Department of Surgery, Emory University School of Medicine, 1364 Clifton Road H124, Atlanta, GA 30322, USA
Am Surg 75:498-502; discussion 502-3. 2009..Patients undergoing AB only exhibited reduction in peripheral insulin resistance at 6 months but no changes in insulin secretion... - Calcium plus vitamin D supplementation and the risk of fracturesRebecca D Jackson
Division of Endocrinology, Ohio State University, 485 McCampbell, 1581 Dodd Dr, Columbus, OH 43210, USA
N Engl J Med 354:669-83. 2006..The efficacy of calcium with vitamin D supplementation for preventing hip and other fractures in healthy postmenopausal women remains equivocal... - Little time for diabetes management in the primary care settingCatherine S Barnes
Divisions of Endocrinology and Metabolism, and General Internal Medicine, Department of Medicine, Emory University School of Medicine, Grady Health Systems, Atlanta, Georgia, USA
Diabetes Educ 30:126-35. 2004..Given the time pressures on the primary care practitioner and the need for better diabetes care, it is essential to teach an efficient but systematic approach to diabetes care... - Relationship of depression to diabetes types 1 and 2: epidemiology, biology, and treatmentDominique L Musselman
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Biol Psychiatry 54:317-29. 2003..Future research will confirm whether response to psychotherapy and/or psychopharmacologic treatment improves glucose control, encourages compliance with diabetes treatment, and perhaps even increases longevity... - Increases in adiponectin predict improved liver, but not peripheral, insulin sensitivity in severely obese women during weight lossEdward Lin
Department of Surgery, Emory University School of Medicine, 1364 Clifton Road, Atlanta, GA 30322, USA
Diabetes 56:735-42. 2007..Thus, in severely obese women, specific loss of VAT leads to acute improvements in hepatic insulin sensitivity mediated by increases in adiponectin and in peripheral insulin sensitivity mediated by decreases in CRP... - Improvement in ß-cell function in patients with normal and hyperglycemia following Roux-en-Y gastric bypass surgeryEdward Lin
Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA
Am J Physiol Endocrinol Metab 299:E706-12. 2010..For both normoglycemic and hyperglycemic subjects, further improvement or stabilization of ?-cell function over the 2 yr is due largely to improved Si associated with reduced adiposity... - Estrogen plus progestin and the risk of peripheral arterial disease: the Women's Health InitiativeJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Circulation 109:620-6. 2004..This analysis evaluates clinical peripheral arterial disease among generally healthy women in the Women's Health Initiative randomized trial of estrogen plus progestin... - Efficacy of inhaled insulin in patients with type 2 diabetes not controlled with diet and exercise: a 12-week, randomized, comparative trialRalph A DeFronzo
University of Texas Health Science Center, Diabetes Division, 7703 Floyd Curl Dr, San Antonio, TX 78284, USA
Diabetes Care 28:1922-8. 2005..This study investigates whether inhaled insulin (INH; Exubera) can achieve target glycemic control in patients failing on diet and exercise... - Relative risk of glucose elevation during antipsychotic exposure in a Veterans Administration populationErica Duncan
Mental Health Service, Atlanta VA Medical Center, Decatur GA 30033, USA
Int Clin Psychopharmacol 22:1-11. 2007..These data indicate that patients with no previously observed glucose elevations develop diabetes-level hyperglycemia during antipsychotic treatment, particularly in patients receiving olanzapine... - Comment on: Buchanan (2007) (How) can we prevent type 2 diabetes? Diabetes 56:1502-1507Lawrence S Phillips
Diabetes 56:e19. 2007 - Validity of diabetes self-reports in the Women's Health Initiative: comparison with medication inventories and fasting glucose measurementsKaren L Margolis
HealthPartners Research Foundation, Minneapolis, MN 55440 1524, USA
Clin Trials 5:240-7. 2008..Therefore, we studied whether self-report of prevalent and incident diabetes in Women's Health Initiative (WHI) participants was concordant with other diagnostic evidence of diabetes... - Proteomic profiling of nonenzymatically glycated proteins in human plasma and erythrocyte membranesQibin Zhang
Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
J Proteome Res 7:2025-32. 2008.... - Oophorectomy, hormone therapy, and subclinical coronary artery disease in women with hysterectomy: the Women's Health Initiative coronary artery calcium studyMatthew A Allison
University of California San Diego, La Jolla, CA, USA
Menopause 15:639-47. 2008..In this study, we aimed to determine the associations between coronary artery calcium (CAC) and hysterectomy, oophorectomy, and hormone therapy use with a focus on the duration of menopause for which there was no hormone therapy use... - Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: a retrospective cohort studyThomas E Delea
Policy Analysis, Brookline, Massachusetts 02455, USA
Diabetes Care 26:2983-9. 2003..To compare the incidence of heart failure in individuals with type 2 diabetes receiving thiazolidinediones (TZDs) versus other oral antihyperglycemic agents... - It's time to overcome clinical inertiaLawrence S Phillips
Ann Intern Med 148:783-5. 2008
Research Grants
- IMPROVING PRIMARY CARE OF AFRICAN AMERICANS WITH NIDDMLawrence Phillips; Fiscal Year: 2001..Our interventions should delineate approaches effective in a primary care setting, as needed to improve care and prevent complications in urban African-Americans with NIDDM. ..
- Screening for IGT: Glucose Challenge vs Predictive ModelLawrence Phillips; Fiscal Year: 2007..By applying existing knowledge to disease control and prevention, our Specific Aims are the critical first steps to solve this problem. ..