A Panov

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease
    Alexander V Panov
    Emory Center for Neurodegenerative Diseases, Emory University School of Medicine, Whitehead Biomedical Research Building, 615 Michael Street, Room 575, Atlanta, GA 30322, USA
    Arch Biochem Biophys 410:1-6. 2003
  2. ncbi Quantitative evaluation of the effects of mitochondrial permeability transition pore modifiers on accumulation of calcium phosphate: comparison of rat liver and brain mitochondria
    Alexander V Panov
    Department of Neurology and the Center for Neurodegenerative Disease, Emory University, Whitehead Biomedical Research Building, Room 575, 615 Michael St, Atlanta, GA 30322, USA
    Arch Biochem Biophys 424:44-52. 2004
  3. ncbi Ca2+-induced permeability transition in human lymphoblastoid cell mitochondria from normal and Huntington's disease individuals
    Alexander V Panov
    Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, GA 30322, USA
    Mol Cell Biochem 269:143-52. 2005
  4. ncbi Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines
    Alexander V Panov
    Department of Neurology, Emory University School of Medicine, Whitehead Biomedical Research Building, 615 Michael Street, Atlanta, Georgia 30322, USA
    Nat Neurosci 5:731-6. 2002
  5. ncbi An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage
    Todd B Sherer
    Center for Neurodegenerative Disease and Department of Neurology, Emory University, Atlanta, Georgia 30322, USA
    J Neurosci 22:7006-15. 2002
  6. ncbi Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease
    Todd B Sherer
    Center for Neurodegenerative Disease, Rollins School of Public Health, Atlanta, Georgia 15213, USA
    J Neurochem 100:1469-79. 2007

Detail Information

Publications6

  1. ncbi In vitro effects of polyglutamine tracts on Ca2+-dependent depolarization of rat and human mitochondria: relevance to Huntington's disease
    Alexander V Panov
    Emory Center for Neurodegenerative Diseases, Emory University School of Medicine, Whitehead Biomedical Research Building, 615 Michael Street, Room 575, Atlanta, GA 30322, USA
    Arch Biochem Biophys 410:1-6. 2003
    ..These results suggest that the mitochondrial calcium handling defects seen in Huntington's disease cell lines and transgenic mice may be due, in part, to direct, deleterious effects of mutant huntingtin on mitochondria...
  2. ncbi Quantitative evaluation of the effects of mitochondrial permeability transition pore modifiers on accumulation of calcium phosphate: comparison of rat liver and brain mitochondria
    Alexander V Panov
    Department of Neurology and the Center for Neurodegenerative Disease, Emory University, Whitehead Biomedical Research Building, Room 575, 615 Michael St, Atlanta, GA 30322, USA
    Arch Biochem Biophys 424:44-52. 2004
    ..We also conclude that ANT affects PT by changing mitochondrial capacity for energization...
  3. ncbi Ca2+-induced permeability transition in human lymphoblastoid cell mitochondria from normal and Huntington's disease individuals
    Alexander V Panov
    Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, GA 30322, USA
    Mol Cell Biochem 269:143-52. 2005
    ..We suggest that HD-htt promotes low H+ conductance of the mitochondria by interacting with proteins at the contacts sites without directly promoting PT or hampering mitochondrial oxidative phosphorylation...
  4. ncbi Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines
    Alexander V Panov
    Department of Neurology, Emory University School of Medicine, Whitehead Biomedical Research Building, 615 Michael Street, Atlanta, Georgia 30322, USA
    Nat Neurosci 5:731-6. 2002
    ..Thus, mitochondrial calcium abnormalities occur early in HD pathogenesis and may be a direct effect of mutant huntingtin on the organelle...
  5. ncbi An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage
    Todd B Sherer
    Center for Neurodegenerative Disease and Department of Neurology, Emory University, Atlanta, Georgia 30322, USA
    J Neurosci 22:7006-15. 2002
    ....
  6. ncbi Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease
    Todd B Sherer
    Center for Neurodegenerative Disease, Rollins School of Public Health, Atlanta, Georgia 15213, USA
    J Neurochem 100:1469-79. 2007
    ....