Research Topics
| Costas G HadjipanayisSummaryAffiliation: Emory University Country: USA Publications
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Publications
Brain cancer propagating cells: biology, genetics and targeted therapiesCostas G Hadjipanayis
Laboratory of Molecular Neuro Oncology, Department of Neurosurgery, Emory University, School of Medicine, Atlanta, GA 30322, USA
Trends Mol Med 15:519-30. 2009..Ultimately, treatments that include specific targeting of BCPCs might potentially be more effective at treating the entire tumor mass, translating to improved patient survival and quality of life...
Current and future clinical applications for optical imaging of cancer: from intraoperative surgical guidance to cancer screeningCostas G Hadjipanayis
Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA 30322, USA
Semin Oncol 38:109-18. 2011..The use of optical imaging is now being applied in the clinic and operating room for the localization and resection of malignant tumors in addition to screening for cancer...
Therapeutic efficacy of a herpes simplex virus with radiation or temozolomide for intracranial glioblastoma after convection-enhanced deliveryCostas G Hadjipanayis
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Mol Ther 16:1783-8. 2008..01), respectively. Intracerebral d106 CED resulted in a significant increase in athymic nude mouse survival when combined with IR or TMZ. d106 CED allows for distribution of HSV-1 in human GBM xenografts and persistent viral infection...
EGFRvIII antibody-conjugated iron oxide nanoparticles for magnetic resonance imaging-guided convection-enhanced delivery and targeted therapy of glioblastomaCostas G Hadjipanayis
Brain Tumor Nanotechnology Laboratory, Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Cancer Res 70:6303-12. 2010....
Tumor initiating cells in malignant gliomas: biology and implications for therapyCostas G Hadjipanayis
Departments of Neurosurgery, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 33022, USA
J Mol Med (Berl) 87:363-74. 2009..The development of new therapeutic strategies selectively targeting TICs while sparing NSCs may provide for more effective treatment of malignant gliomas...
Full scope of optionsCostas G Hadjipanayis
Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia 30322, USA
Neurosurgery 67:197-203; discussion 203-4. 2010..This illustration is accompanied by a brief review of the literature on the topic...
Inhibition of DNA repair by a herpes simplex virus vector enhances the radiosensitivity of human glioblastoma cellsCostas G Hadjipanayis
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
Cancer Res 65:5310-6. 2005....
Exciting new advances in neuro-oncology: the avenue to a cure for malignant gliomaErwin G Van Meir
Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA
CA Cancer J Clin 60:166-93. 2010....
Open biopsy in patients with acute progressive neurologic decline and absence of mass lesionAlbert J Schuette
Department of Neurological Surgery, Emory University, Atlanta, GA, USA
Neurology 75:419-24. 2010....
Magnetic nanoparticles: an emerging technology for malignant brain tumor imaging and therapyMamta Wankhede
Brain Tumor Nanotechnology Laboratory, Department of Neurosurgery, Emory University School of Medicine, Winship Cancer Institute of Emory University, 1365B Clifton Road NE, Suite 6200, Atlanta, GA 30322, USA
Expert Rev Clin Pharmacol 5:173-86. 2012..Future translational studies are in progress to understand the promising impact of MNPs in the treatment of malignant brain tumors...
Surgery of intrinsic cerebral tumorsMitchel S Berger
Department of Neurosurgery, University of California at San Francisco, 505 Parnassus Avenue, Room M787, San Francisco, California 94143, USA
Neurosurgery 61:279-304; discussion 304-5. 2007..This would be a paradigm shift away from stimulation mapping, which currently deactivates the cortex, as opposed to identifying an activation function which identifies functional cortex...
Individualized treatment of pediatric craniopharyngiomasA Leland Albright
Department of Neurosurgery, Childrens Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA
Childs Nerv Syst 21:649-54. 2005..We performed this study to correlate the clinical and radiographic features at the time of presentation with the multimodality treatments the children received...
The role of stereotactic radiosurgery for low-grade astrocytomasCostas G Hadjipanayis
Department of Neurological Surgery, Center for Image Guided Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Neurosurg Focus 14:e15. 2003..This study was conducted to examine the role of radiosurgery in the management of patients with recurrent or unresectable low-grade astrocytomas...
Management of cystic craniopharyngiomas with phosphorus-32 intracavitary irradiationToshinori Hasegawa
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA
Neurosurgery 54:813-20; discussion 820-2. 2004..CONCLUSION: For patients with cystic craniopharyngiomas, (32)P intracavitary irradiation proved effective, with a low risk of complications, for the control of tumor cysts but not of solid tumor components...
